The invention discloses a graphene shoulder and neck pain patch comprising a backing layer, a graphene film layer, a raw material medicine layer and an anti-sticking release paper layer. The raw material medicine layer is placed between the anti-sticking release paper and the backing layer; a raw material medicine is in the middle position of the raw material medicine layer and comprises the following substances: radix angelica sinensis, rhizoma gastrodiae, pilose antler, radix saposhnikoviae, notopterygium root, radix angelicae tuhuo, baked ginger, asarum sieboldii, fructus evodiae, safflower, radix dipsaci and garden balsam stem; the raw material medicine is also mixed with sodium hydroxymethylcellulose, sodium alginate and glycerol, so the raw material medicine is uniform in coating, has good adhesion and does not produce greater fluidity; the outer side of the raw material medicine is laid with the graphene film layer which can effectively activate the vitality of damaged cells andrestore normal function. The graphene shoulder and neck pain patch has the advantages of low price and convenient and quick use, and has the functions of relaxing tendons and dredging collaterals, activating blood circulation and promoting qi. The graphene film layer at the bottom layer can effectively promote the transmission of drugs, accelerates the absorption of the raw material medicine, andhas a good healing effect on shoulder and neck pain and other symptoms.