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results about "Histidine Hydrochloride" patented technology
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STABLE INJECTION OF SECUKINUMAB AND PREPARATION PROCEDURE THEREOF
Active
MX433985B
Secukinumab
Alcohol sugars
The present invention relates to a stable secukinumab injection, characterized in that it comprises 50-250 mg / ml of secukinumab, 5-50 mmol / l of
histidine
and
histidine
hydrochloride
, 5-40 mmol / l of
methionine
, 150-370 mmol / l of low molecular weight
sugar
alcohol
and
polysorbate
80 at 0.01%-0.02% (v / v), in water for injection, pH 5.0-7.0, wherein the low molecular weight
sugar
alcohol
is
xylitol
.
Owner:
TONGHUA DONGBAO PHARMA
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Medicinal chemistry
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Hydrochloride
Xylitol
Sugar alcohol
Methionine