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10 results about "Iodide sodium" patented technology

Vehicle-mounted sodium iodide detection system

1. Name of the product in this design: Vehicle-mounted sodium iodide detection system. 2. Purpose of this design: To receive and process signals from a sodium iodide detector. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.
Owner:SHANGHAI SIM-MAX TECH CO LTD Y

A method for selectively synthesizing 4-amino-N-(hetero)arylsulfonamide compounds

This invention discloses a method for the selective synthesis of 4-amino-N-(hetero)arylsulfonamide compounds. Using bipyridine as a ligand and nickel as a catalyst, and inexpensive and readily available low-activity (hetero)aryl chlorides and 4-aminobenzenesulfonamides as substrates, 1,8-diazabicycloundec-7-ene and other organic bases are used, along with sodium iodide and other additives. The synthesis of various 4-amino-N-(hetero)arylsulfonamide compounds is achieved through a photo-driven nickel-catalyzed selective C-N coupling reaction of (hetero)aryl chlorides and 4-aminobenzenesulfonamides under an argon atmosphere. This invention features a simple reaction system, convenient operation, mild reaction conditions, and simple post-processing. It exhibits good selectivity for target compounds and high yields, avoiding the problems of complex catalytic systems and poor functional group compatibility caused by the use of traditional expensive metal catalysts and inorganic bases. Therefore, it has significant application value and market prospects.
Owner:SHAANXI NORMAL UNIV

Culture medium and culture method of hiPSC-sourced thyroid organoid

PendingCN121801809ACulture processArtificial cell constructsThyroid hormonesSecretion
The invention provides a culture medium and a culture method of a hiPSC-derived thyroid organ, and belongs to the technical field of thyroid organ culture. The invention relates to a culture method of a hiPSC-derived thyroid organ. The culture method comprises the following steps: (1) putting a resuscitated hiPSC-derived thyroid organ into a proliferation culture medium for culturing; and (2) when the thyroid organoid is cultured in the step (1) until the size of the thyroid organoid is 120-150 microns, replacing the proliferation culture medium with a differential culture medium, and continuously culturing. Sodium iodide with a specific concentration is added during thyroid organoid culture, so that the secretion amount of in-vitro thyroxine T4 of the organoid reaches 5ng / ml and is far higher than that (0.023 ng / ml) in the prior art. The invention provides a culture medium and a culture method capable of obviously promoting the maturity of the thyroid organoid, and the culture medium and the culture method have a wide application prospect.
Owner:BEIJING UNIV OF CHINESE MEDICINE SUN SIMIAO HOSPITAL

A processing method of a large-size sodium iodide scintillation crystal for nuclear radiation detection

The present application relates to the field of sodium iodide crystal cutting, and particularly relates to a processing method of large-size sodium iodide scintillation crystal for nuclear radiation detection, comprising: determining an initial cutting point based on a required capacity length; before cutting processing is performed on the single initial cutting point, determining whether to adjust the position of the initial cutting point to obtain an execution cutting point based on a defect cracking index corresponding to the initial cutting point; based on a defect feature interference condition corresponding to a to-be-cut surface of the execution cutting point, determining whether to adjust a cutting speed setting mode from a self-adjusting speed cutting to a minimum speed cutting; and cutting is completed to obtain a target sub-crystal. The present application improves the cutting flexibility and cutting precision of the large-size sodium iodide crystal.
Owner:BEIJING SHENGTONGHEJING SCI & TECH

Synthesis method of 3-mercaptobenzoic acid

The invention discloses a synthesis method of 3-mercaptobenzoic acid, and belongs to the technical field of organic synthesis, the synthesis method comprises the following steps: mixing benzoic acid with a first part of chlorosulfonic acid, reacting at 100-110 DEG C, adding a second part of chlorosulfonic acid, reacting at 120-130 DEG C, cooling, and stirring at 0-5 DEG C to obtain 3-chlorosulfonyl benzoic acid; the preparation method comprises the following steps: mixing anhydrous ethyl lactate, tetrabutylammonium iodide and 3-chlorosulfonylbenzoic acid in an inert environment, heating to 50-55 DEG C, adding a sodium iodide / acetonitrile solution, keeping the temperature, heating to 80-85 DEG C, adding triphenylphosphine, adding formic acid, reacting at 80-85 DEG C, cooling to 60-65 DEG C, adding water, and reacting; the synthesis method provided by the invention can solve the problems of high raw material toxicity, low product yield, poor quality, serious three-waste pollution, high cost and unsuitability for industrialization in the synthesis method of 3-mercaptobenzoic acid in the prior art.
Owner:SHOUGUANG FUKANG PHARMA +4

Dental pulp-derived stem cells expressing sodium iodide symporter

It is an object of the present invention to provide cells, which accumulate in cancer tissues, are guaranteed to be safe for humans, and can be stably prepared. Moreover, it is another object of the present invention to provide a method for diagnosing a cancer and a method for treating a cancer, using the above-described cells expressing NIS, and to provide a composition for use in the diagnostic method and the treatment method. More specifically, the present invention relates to: dental pulp-derived pluripotent stem cells, which express a sodium iodide symporter (NIS); a composition for use in the treatment or diagnosis of a cancer, which is characterized in that the aforementioned cells are combined with a radionuclide; and a method for treating a cancer and a method for diagnosing a cancer, using the aforementioned composition.
Owner:THE UNIV OF TOKYO +1

A material pretreatment device for sodium iodide preparation

This utility model discloses a material pretreatment device for sodium iodide preparation, comprising: a reaction vessel, and a stirring mechanism disposed within the reaction vessel. The stirring mechanism includes: a motor, which is fixedly connected to one outer wall of the reaction vessel; a transmission rod is rotatably connected to one inner wall of the reaction vessel; one end of the motor output shaft passes through the reaction vessel and is fixedly connected to one end of the transmission rod; a first gear is rotatably connected to one inner wall of the reaction vessel, and one side of the first gear is fixedly connected to the other end of the transmission rod; two transmission plates are provided on the circumferential inner wall of the reaction vessel. The motor drives the transmission rod, and the first gear on the transmission rod meshes with the second gear, which in turn meshes with the tooth block in the through hole, thereby causing the transmission plates to drive the first stirring rod to rotate; simultaneously, in the reversing assembly on the transmission rod, the connecting plate drives the shearing rod to rotate, and the second stirring rod and the shearing rod are alternately distributed, which enables all-round and multi-angle stirring of the material in the reaction vessel.
Owner:XUZHOU HUAYI PHARM CO LTD

A dairy cow teat disinfectant that promotes the repair of damaged epidermis, its preparation method and application

This invention relates to the field of disinfectant technology, and more particularly to a dairy cow teat disinfectant that promotes the repair of damaged epidermis, its preparation method, and its application. By weight, the dairy cow teat disinfectant that promotes the repair of damaged epidermis comprises the following raw materials: 0.2-2 parts iodine, 0.1-5 parts sodium iodide, 0.1-0.5 parts sodium iodate, 0.1-10 parts skin-repairing active ingredients, 1-10 parts surfactant, 0.05-0.5 parts thickener, 2-10 parts lubricant, 0.1-0.5 parts wetting agent, and 0.15-1 part pH adjuster, with the balance being water. A novel surfactant, alkyl glycoside, is selected. In the disinfectant system, alkyl glycoside can efficiently complex with iodine to form highly stable complexed iodine, extending the shelf life of the formulation. In addition, the cow teat disinfectant in this solution also contains skin repair ingredients. While maintaining a highly effective bactericidal effect, it can also promote the repair of skin damaged by bacterial infection, promote the healing of abrasions on the cow teat epidermis, and reduce the risk of infection by pathogens due to exposed teat epidermal wounds.
Owner:SOUTH CHINA AGRICULTURAL UNIVERSITY +1

Preparation equipment and method of montelukast sodium intermediate

The application relates to the technical field of pharmaceutical engineering, in particular to a preparation device and method for a montelukast sodium intermediate; the device comprises an evaporation tower and a base at the bottom of the evaporation tower; a liquid inlet pipe is fixed to the lower position of the inner and outer walls of the evaporation tower; a tower cover is arranged on the upper end of the evaporation tower; the lower end of the tower cover is lower than the upper end of the evaporation tower; an air outlet pipe is arranged at the top of the tower cover, and a discharge pipe is arranged at the bottom of the tower cover; a motor is fixed to the top of the tower cover; a central shaft fixed to the output end of the motor extends to the inside center of the evaporation tower; a spiral plate is fixed to the outer wall of the central shaft; the solution at the bottom of the evaporation tower can be continuously stirred into the spiral gap, so that the solution at the bottom of the evaporation tower spreads on the upper surface of the spiral plate after being heated, the heated area of the solution is increased, the evaporation effect of the solution is improved, and the evaporation crystallization efficiency of the potassium iodide or sodium iodide solution is improved.
Owner:BINHAI SANYONG PHARM CHEM CO LTD