11 results about "Ammonium iodide" patented technology

The application discloses a method for synthesizing N-(hetero) aryl sulfonamide compounds. The method uses bipyridine as a ligand, nickel acetate or nickel chloride as a catalyst, low-cost low-activity (hetero) aryl chloride and different types of sulfonamides as substrates, 1,8-diazabicycloundec-7-ene, tetramethyl guanidine, 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene and the like as organic bases, and tetra-n-butylammonium iodide as an additive. The C-N coupling reaction of (hetero) aryl chloride and sulfonamide is realized by light-induced nickel catalysis in an argon atmosphere, so as to realize the synthesis of various (hetero) aryl sulfonamide compounds. The reaction system is simple, the operation is simple, the reaction condition is mild, the post-treatment is simple, the yield is good, the substrate range is wide, the use of traditional expensive metal catalysts and inorganic bases is avoided, the problems of complex catalytic system reaction and poor functional group compatibility are solved, and the method is a simple and efficient method for synthesizing (hetero) aryl sulfonamide compounds. The method has good application prospect.

This invention discloses a process and active carrier catalyst for the catalytic synthesis of acetyl empagliflozin. The process utilizes a yeast cell wall-mediated active carrier nickel-phosphorus composite catalyst. The catalyst is activated in a water / glycerol mixed solvent via microwave-ultrasound dual-field synergistic activation, catalyzing the reaction of compound 5 with compound 4 to obtain compound 3. In a supercritical CO2 / ionic liquid system, leveraging the photoisomerization properties of spiropyran-quaternary ammonium iodide, under low-voltage electrocatalysis and UV-Vis switching conditions, the directional glycosylation reaction of compound 3 with compound 2 is achieved to obtain compound 1. This invention utilizes the porous structure and functional groups of the yeast cell wall to stabilize nano-nickel-phosphorus particles, improving catalytic efficiency and reusability. Through the synergistic guiding effect of photoresponsive molecules and ionic liquids, high selectivity of the reaction is achieved. The entire process uses green solvents, and a closed-loop catalyst recovery process is established, offering advantages such as environmental friendliness, low cost, and high product purity.

This invention relates to the field of solid-state refrigeration materials with pressure-sensitive effects, and discloses a technical method for improving the adiabatic temperature change decay of plastic crystal materials under constant pressure cycling conditions. The method involves uniformly mixing ammonium iodide plastic crystal grains with silicone oil to form a coating composite system with lubricating and isolating functions. A spherical shell encapsulation structure is then fabricated using PA12 nylon powder via laser sintering 3D printing. The composite system is filled and sealed within the spherical shell to form a stable encapsulation unit. During programmed pressurization and depressurization cycles of the encapsulation unit under constant pressure conditions, the silicone oil effectively reduces inter-grain friction and stress concentration, while the spherical shell structure prevents the loss of the coating medium and maintains the integrity of the system, thereby significantly suppressing the decay of the adiabatic temperature change of the plastic crystal material with increasing cycle count.

The application discloses a kind of supermolecular hybrid hydrogel continuously generating hydroxyl radical, wherein the supermolecular hybrid hydrogel is composed of sodium hyaluronate and a nanocomposite, the sodium hyaluronate is the substance forming the network structure of the supermolecular hybrid hydrogel, the nanocomposite is distributed in the network structure, and the nanocomposite is the complex of beta-cyclodextrin modified upconversion nanoparticle and (ferrocene methyl) trimethyl ammonium iodide;Wherein the mass ratio of beta-cyclodextrin modified upconversion nanoparticle and (ferrocene methyl) trimethyl ammonium iodide complex: sodium hyaluronate: deionized water is 52: (17.5-20): 1000.The supermolecular hybrid hydrogel of the application can catalyze the reverse Fenton reaction under the tumor microenvironment, in situ cyclic generation of hydroxyl radical, and has potential application in the treatment of malignant tumors.

Manufacturing semiconductor device includes forming photoresist layer. Photoresist layer is selectively exposed to actinic radiation and developed to form pattern. Photoresist composition includes: iodine-containing sensitizer, photoactive compound, polymer. Iodine-containing sensitizer includes ammonium, phosphonium, or heterocyclic ammonium iodides,where X1, X2, X3, and X4 are independently direct bond, C6-C30 iodo-aryl group, C1-C30 iodo-alkyl group, C3-C30 iodo-cycloalkyl group, C1-C30 iodo-hydroxylalkyl group, C2-C30 iodo-alkoxy group, C3-C30 iodo-alkoxyl alkyl group, C1-C30 iodo-acetyl group, C2-C30 iodo-acetylalkyl group, C1-C30 iodo-carboxyl group, C2-C30 iodo-alky carboxyl group, and C4-C30 iodo-cycloalkyl carboxyl group; C3-C30 saturated or unsaturated iodo-hydrocarbon ring, or C3-C30 iodo-heterocyclic group; A1, A2, A3, A4 are independently acid labile group selected from C6-C15 iodo-aryl group, C4-C15 iodo-alkyl group, C4-C15 iodo-cycloalkyl group, C4-C15 iodo-hydroxylalkyl group, C4-C15 iodo-alkoxy group, and C4-C15 iodo-alkoxyl alkyl group.

The application provides a BiOI with iodine defects 1‑x Rod-like material, preparation method and application thereof. Bismuth nitrate pentahydrate and 1,3,5-benzene tricarboxylic acid are added into methanol in proportion, and a metal organic framework [Bi9(C9H3O6)·9(H2O)9] is synthesized by heating at 100-140 DEG C for 20-24 h; the metal organic framework is mixed with ammonium iodide in proportion, and then is subjected to water bath at 60-100 DEG C for 0.5-1.5 h to derive rod-like BiOI; the obtained BiOI is calcined in a muffle furnace at 350-450 DEG C to obtain the rod-like BiOI material with iodine defects, which is represented as BiOI 1‑x . The material has the rod-like microstructure of the precursor [Bi9(C9H3O6)·9(H2O)9], the axial size is slightly reduced, the diameter of the rod is about 1-2 microns, the length is about 3-8 microns, the surface is rough, and the material has a porous structure. The material can be used as a photocatalyst for degradation of gaseous formaldehyde and liquid tetracycline, and both have excellent degradation performance.

A method for electrochemically driving 2-(1-alkynyl)benzamide derivative to cyclize and synthesize iodoisoindolone, in which 2-(1-alkynyl)benzamide derivative and tetrabutylammonium iodide are used in an electrolyte and a solvent at room temperature to obtain iodoisoindolone. The electrochemical driving efficiency is higher, the substrate conversion rate is increased to 95%, heavy metal residues are avoided, the requirements of drug intermediates are met, no temperature control energy consumption is needed, the process is simplified, the efficiency is improved, and the functional group tolerance is better.

A method for preparing lignan-derived schisandrol A, belonging to the field of medicinal chemistry. The method comprises: 1. Preparing intermediate 1 using 3,4,5-trimethoxybenzaldehyde and N-bromosuccinimide; 2. Preparing intermediate 2 using intermediate 1, a nickel catalyst, a ligand, tetrabutylammonium iodide, and zinc powder; 3. Preparing intermediate 3 using intermediate 2, methyl chloropropionate, and an organic base; 4. Preparing intermediate 4 using intermediate 3, ethyltriphenylphosphine bromide, and potassium tert-butoxide; 5. Preparing intermediate 5 using intermediate 4, an alkaline solution, and hydrochloric acid; 6. Preparing lignan-derived schisandrol A using intermediate 5, a samarium catalyst, hexamethylphosphoramide, and tert-butanol. This invention optimizes the reaction pathway, requiring only 6 steps to efficiently synthesize schisandrol A, significantly shortening the traditional synthetic route, improving overall reaction efficiency and the total yield of the target product. Tests show that schisandrol A has good antibacterial activity against *Escherichia coli* and *Staphylococcus aureus*.

The application discloses a synthesis method of an electrochemical promoted selenophenyl substituted alkyne derivative. The specific steps are as follows: a four-necked flask is sequentially added with tetrabutylammonium iodide, a diselenide derivative and a solvent, an acetylene balloon is connected, and the reaction is stirred at room temperature under electricity for 7 hours; and the crude product is separated and purified through column chromatography to obtain the target product. The method realizes efficient synthesis of the selenophenyl substituted alkyne derivative under electrochemical conditions, does not need a metal catalyst and an equivalent toxic oxidant, and can realize effective fixation of acetylene only at room temperature and under normal pressure. The strategy has environmental friendliness and simple operation, and significantly improves the practicability of synthesis.

The application discloses a preparation method of 5,6-dimethoxy-1-indanone and belongs to the technical field of medical intermediates. The preparation method comprises the following steps: 5-indanol is used as raw material, and under the action of an oxidant and a tetrabutylammonium iodide catalyst, intermediate A and intermediate B mixture are generated; then, complex reaction with borate ester is carried out, and intermediate B is separated out through distillation; then, reduction reaction is carried out, and 5,6-indandiol is generated; then, methyl etherification reaction is carried out through dimethyl sulfate; finally, CrO3 and Ac2O oxidation system are used to oxidize, and 5,6-dimethoxy-1-indanone is generated. The application adopts borate ester to separate isomers, and the operation is simple, which provides a new idea for synthesizing the compounds.