The invention discloses a maintenance wiping method and a maintenance wiping wet tissue for an ink-jet printer nozzle. The maintenance wiping wet tissue is composed of the following components including, by weight, 10% of NPGDA, 33% of TPGDA, 24% of HDDA, 23% of DPGDA and 10% of a surfactant. A using method of the maintenance wiping method for the ink-jet printer nozzle comprises the following steps that 1, materials are prepared, wherein foam and a wet tissue body are prepared; 2, the foam is taken up and placed flatly; and 3, the viscous force of a hook-and-loop fastener loop surface and a hook-and-loop fastener hook surface are overcome, a fixing band is uncovered, and one end of the fixing band is far away from the foam. The maintenance wiping method and the maintenance wiping wet tissue for the ink-jet printer nozzle has the beneficial effects that a traditional ink-jet printer nozzle maintenance wiping method is changed, the wiped nozzle is not damaged, head drying, head blockingand damage of the nozzle cannot be caused, the wiping effect is obvious, the service life of the nozzle is prolonged, the cost is saved, and the consumption is reduced; and due to the addition of thesurfactant, the sterilization effect is improved.