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271 results about "Decreased serum IgA" patented technology

Application of polyhydroxy bromo-benzophenone compound and derivatives thereof in treatment and prevention of atherosclerosis

The invention discloses application of a polyhydroxy bromo-benzophenone compound and derivatives of the polyhydroxy bromo-benzophenone compound in treatment and prevention of atherosclerosis, and belongs to the technical field of medicines. According to the application of the polyhydroxy bromo-benzophenone compound in the treatment and the prevention of the atherosclerosis, an active ingredient is the polyhydroxy bromo-benzophenone compound 2,4',5'-trihydroxy-5,2'-dibromo-benzophenone, and according to the application of the derivatives of the polyhydroxy bromo-benzophenone compound in the treatment and the prevention of the atherosclerosis, active ingredients are medicinal salt, medicinal ester and medicinal ether of the 2,4',5'-trihydroxy-5,2'-dibromo-benzophenone. Due to the fact that the expression of triglyceride (TG) and low density lipoprotein-cholesterol (LDL-C) in blood serum is reduced, and the expression of inflammatory factors including interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) and adhesion molecules sICAM-1 in the blood serum is restrained, vascular endothelial injuries are restrained, and vascular endothelia are protected, so that occurrence and development of the atherosclerosis (AS) are restrained, and more broad prospects are opened up for clinical medication.
Owner:SHANXI MEDICAL UNIV

Dihydrochalcone derivates and use thereof

The invention relates to the technical field of medicines. Chalcone is a natural component in plants and has antibiotic and antifungal effects, and derivatives of the chalcone also have the effect of resisting tumors and the like. At present, no document is reported that the derivatives of the chalcone have the effect of reducing activity of blood fat and protecting the liver. The invention provides derivatives of the dihydrochalcone having a general formula I. Through tests of reducing blood fat, the results show that the derivatives of the dihydrochalcone have the effects of obviously reducing serum total cholesterol and low-density lipoprotein cholesterol, and can be used to prepare medicines or health products for reducing blood fat, preventing and treating hyperlipoidemia, fatty liver, hepatocirrhosis and atherosclerosis and protecting the liver.
Owner:SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY

Traditional Chinese medicine composition for treatment of chronic renal diseases and chronic renal failure and its preparation method and use

The invention provides a traditional Chinese medicine composition for treatment of chronic renal diseases and chronic renal failure and its preparation method. The traditional Chinese medicine composition is prepared from the following raw material medicines by weight: 6-40 parts of rheum officinale, 10-95 parts of astragalus and 5-65 parts of salvia miltiorrhiza by a certain extraction and purification process into an injection, a freeze-dried powder injection or other oral preparations. Animal experiments confirm that, the traditional Chinese medicine composition can obviously improve the hemodynamic indexes of rats subjected to chronic glomerulonephritis, reduces serum IL-6, IL-8, and TNF (tumor necrosis factor)-alpha levels, significantly reduces serum creatinine and urea nitrogen and other indexes of rats subjected to hypertensive nephropathy, significantly reduces serum urea nitrogen and serum creatinine contents of rats subjected to the chronic renal failure, increases serum albumin content, and also can improve each hemodynamic index of rats subjected to the chronic renal failure; and pathological results show that the traditional Chinese medicine composition can improve and inhibit injures on kidney caused by the chronic renal diseases and chronic renal failure.
Owner:XIAN SHIJISHENGKANG PHARMA IND

Fructo-oligosaccharide bovine bone marrow peptide powder composition and application thereof

The present invention discloses a fructo-oligosaccharide bovine bone marrow peptide powder composition. The composition comprises fructo-oligosaccharides, bovine marrow peptide powder and probiotic powder. In the fructo-oligosaccharide bovine bone marrow peptide powder composition, functions of the bovine bone marrow peptide powder are mainly hematopoiesis and blood supplementation, contained phosphorus can help calcium precipitation and absorption, and thus improve human body immune system, functions of the fructo-oligosaccharide are promoting expelling of toxins (expelling of liver toxins),lowering serum cholesterol and triglycerides, promoting absorption of calcium and other minerals, and enhancing immune regulation, and functions of the probiotic powder are supplementing losses of probiotics during the toxin expelling process; the process of the fructo-oligosaccharide in lowering the serum cholesterol and triglycerides is the process of removing human body waste, so that an original "body deficiency" is manifested, then the hematopoiesis and blood supplementation of the bovine bone marrow peptide powder enable human body immune system to be truly enhanced; and the three substances achieve a very good synergistic effect and the fructo-oligosaccharide bovine bone marrow peptide powder is an excellent blood-supplementing and human-immunity-enhancing health-care product.
Owner:广东肽世家生物科技有限公司

Polystictus glycopeptide active component as well as preparation method and application thereof

InactiveCN108130280AGood treatment effectThe molecular weight of the substance decreasesFungiHydrolysed protein ingredientsCholesterolGlycopeptide
The invention discloses a polystictus glycopeptide active component as well as a preparation method and application thereof. The polystictus glycopeptide active component comprises the following steps: preparation of coriolus versicolor mycelium; extraction of the polystictus glycopeptide active component from the coriolus versicolor mycelium; separation, purification and enzymatic hydrolysis of the polystictus glycopeptide active component. The active component is found by comparing the therapeutical effect of the polystictus glycopeptide active component on an acute alcoholic liver injury mouse model to better reduce the vitalities of AST and ALT in serum, reduce the contents of Triglycerid, MDA, NEFA, TC and LDL-TC in the serum, improve the content of HDL-TC in the serum and realize thebetter therapeutical effect of resisting alcoholic liver injury. According to the preparation method disclosed by the invention, active functional factors for preventing and treating the alcoholic liver injury are found from natural food resources; the obtained polystictus glycopeptide active component can reduce indicators of the ALT, the AST, cholesterol, free fatty acid and the like in the serum, and has a good application value and a potential market prospect in aspects of preventing and treating alcoholic liver disease, fatty liver or hyperlipidemia.
Owner:JIANGSU SHENHUA PHARMA +1

Composite fungal intercellular polysaccharide composition with liver protecting function and preparation method

The invention discloses a composite fungal intercellular polysaccharide composition with a liver protecting function and a preparation method. The composite fungal intercellular polysaccharide composition comprises 10-45 weight parts of coprinus comatus intercellular polysaccharide, 20-50 weight parts of white fungus intercellular polysaccharide and 20-45 weight parts of hohenbuehelia serotina intercellular polysaccharide. The preparation method comprises the steps of fermenting fungi, crushing the separated mycelia, adding enzyme for reacting, and separating solid and liquid phases; adding distilled water into the solid phase, then performing ultrasonic treatment, adding ethanol liquid, collecting and drying the sediment; concentrating the liquid phase, adding ethanol, standing, centrifuging to separate the sediment; combining the sediments obtained by solid and liquid phase treatment to obtain homogenous intercellular polysaccharides; and mixing the coprinus comatus intercellular polysaccharide, the white fungus intercellular polysaccharide and the hohenbuehelia serotina intercellular polysaccharide obtained by the method respectively to obtain the composite fungal intercellular polysaccharide composition with the liver protecting function. The composition has the advantages of effectively reducing the ALT (alanine aminotransferase) and AST (aspartate aminotransferase) level of serum, obviously reducing the malonaldehyde content of injured liver and obviously promoting biliary excretion so that the function of the injured liver can be recovered.
Owner:JILIN MODERN TRADITIONAL CHINESE MEDICINE ENG RES CENT

Application of elaeagnus conferta roxb

The invention discloses an application of elaeagnus conferta roxb, namely the application of the elaeagnus conferta roxb in preparation of drugs for treating kidney stones, gall-stone and hyperuricemia. In the treatment of the kidney stones, the drug is used for reducing the rate of the kidney stones, improving kidney coefficient, reducing calcium content of the kidney, reducing serum urea nitrogen and reducing serum creatinine. In the treatment of the gall-stone, the elaeagnus conferta roxb is used for treating bile pigment gallstones and cholesterol gallstones; preferably in the treatment of bilirubin gallstones, the elaeagnus conferta roxb is used for reducing the rate of the gallbladder stones, calcium ion content in bile, total bilirubin concentration and free bilirubin concentration in the treatment of the bile pigment gallstones; in the treatment of the cholesterol gallstones, the elaeagnus conferta roxb is used for reducing the rate of the gallbladder stones and the cholesterol content in the bile; and in the treatment of hyperuricemia, the elaeagnus conferta roxb is used for reducing uric acid content in serum. The application of the elaeagnus conferta roxb can be spread to related products of the elaeagnus conferta roxb; and the related product includes a fruit aqueous extract of the elaeagnus conferta roxb, dewatered elaeagnus conferta roxb, capsules, troches, granulas, fruit vinegar, jam and fruit juice.
Owner:盛艳
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