32 results about "Diquat" patented technology

The invention discloses a herbicide and a preparation method thereof, and belongs to the technical field of herbicides. The herbicide is mainly prepared in the mode that graphene oxide adsorbs diquat molecules and is loaded on ZIF-8, and the ZIF-8 is spontaneously formed on the outer layer. The herbicide has visible light and pH responsiveness, graphene oxide can be rapidly combined with diquat molecules, meanwhile, the good photo-thermal conversion effect is achieved, disintegration of materials is accelerated through heat absorption under irradiation of visible light, the release rate of the herbicide is increased, the problem that the release rate of ZIF-8 wrapped herbicides in practical application is not consistent with the requirement is solved, and the herbicide has good application prospects. The ZIF-8 can improve the adhesion on the leaves, increase the retention volume of diquat on the leaf surfaces of weeds, increase the utilization rate of diquat, enable the diquat to have longer effect time, and have good application prospects in practical application.

The utility model relates to an aquacide dichlorine water agent mixing and batching device, which aims to solve the technical problem that the stirring and mixing effect is influenced because the current stirring area is not changed, and comprises a batching tank and a hollow shaft, the hollow shaft penetrates through the top of the batching tank and extends to the lower side of the inner cavity of the batching tank, and the upper side of the outer wall of the hollow shaft is fixedly sleeved with a gear ring; according to the stirring device, the electric push rod is used for driving the lifting column to ascend and descend, so that the movable rod is driven to ascend and descend, the rack can be driven to drive the gear to rotate, the stirring blades are driven to rotate, and the stirring blades are driven to rotate. The stirring blades are driven to alternately rotate in a reciprocating manner, so that the liquid stirring angle can be changed, stirring in the horizontal direction can be achieved, the stirred liquid has the tendency of moving up and down, and the material stirring and mixing effect is improved.

The invention relates to the technical field of oil and gas well development, in particular to a temperature-resistant thixotropic agent and a preparation method and application thereof. The preparation method comprises the following steps: carrying out graft modification on diquat glue by adopting acrylic acid and N-vinyl pyrrolidone to obtain modified diquat glue; and compounding the modified diquat and aluminum-magnesium silicate to prepare the temperature-resistant thixotropic agent. The temperature-resistant thixotropic agent prepared by the invention can remarkably improve the thixotropic property of magnesium oxychloride cement in a high-temperature environment of an oil and gas well, effectively improve the rheological property of cement paste, enhance the retention capacity of the cement paste in cracks, improve the plugging stability and the like, and has a wide application prospect in oil and gas well engineering. And powerful support is provided for solving the well leakage problem of the fractured formation in the oil and gas well drilling process.

The invention belongs to the field of pesticide poisoning prognosis, and particularly discloses a method for establishing an acute diquat pesticide poisoning prediction death risk index, which comprises the following steps: collecting data; establishing a death risk index model based on demographic characteristics and blood routine test results; and carrying out model training, internal verification and external verification. The death risk index provided by the invention comprehensively considers age, diquat blood concentration, leukocyte count and glutamic oxalacetic transaminase concentration, and aims to accurately evaluate the death risk of acute diquat pesticide poisoning patients in an index form. Through deep analysis of large-scale clinical data, the death risk index of the invention not only has scientificity and accuracy on the data level, but also can play an important role in clinical practice, can be applied to construction of acute diquat pesticide poisoning death risk prediction terminal equipment, helps medical teams to distribute medical resources more reasonably, and has a good application prospect. High-risk patients are preferentially processed, so that the overall treatment effect and the survival opportunity of the patients are improved.

The present application belongs to the field of pesticides, and particularly relates to a herbicidal composition containing a fused ring substituted aromatic compound and application thereof. The composition comprises a herbicidally effective amount of active ingredient A and active ingredient B, wherein the active ingredient A is or a salt / ester thereof; the active ingredient B is selected from one or more of the following compounds and salts / esters thereof: glyphosate, glufosinate-ammonium, glufosinate-P, paraquat, diquat, ACCase inhibitors, PPO inhibitors, etc. The composition can effectively control / eliminate grass weeds and broadleaf weeds, etc., and has the characteristics of expanding the herbicidal spectrum, reducing the application amount, being able to produce a synergistic effect and solving the problem of resistant weeds, etc.

The invention discloses a preparation method of an MF (at) NH2 (at) Ag SERS (Surface Enhanced Raman Scattering) sensor for detecting paraquat and diquat, belongs to the field of nano material synthesis and spectral analysis, and solves the problems that a traditional detection method is complicated in process and cannot detect pesticides and free radicals thereof at the same time, and a traditional SERS substrate is poor in enhancement effect and low in stability. The preparation method comprises the following steps: firstly segmenting melamine foam, cleaning and drying, soaking in hydrochloric acid, soaking in a polyethyleneimine aqueous solution to modify amino, drying, soaking in a silver nitrate solution for ultrasonic treatment, adding a sodium borohydride solution under an ice bath, stirring and reducing, and finally cleaning and drying to obtain the sensor. The sensor takes three-dimensional melamine foam as a support, silver nanoparticles are uniformly loaded on the surface of the three-dimensional melamine foam, paraquat, aquacide and free radicals thereof are enriched through electrostatic interaction based on a localized surface plasma resonance principle, and Raman signal enhancement is realized. The detection limit is 10 <-9 > mol / L, the signal stability and repeatability are excellent, the applicability to actual water sample detection is good, the detection of other pesticides can be expanded, and the method is suitable for on-site rapid trace detection.

The invention discloses a method for continuously preparing flake diquat dichloride by a microfluidic reactor, which includes: using a feeding pump to input liquid 2,2'-bipyridine or a 2,2'-bipyridine solution dissolved in a solvent, dichloroethane or a dichloroethane solution into the microfluidic reactor, quickly mixing and precipitating, separating solid from liquid, washing with toluene, and drying to obtain flake diquat dichloride; a dispersant is added to the liquid 2,2'-bipyridine or the 2,2'-bipyridine solution dissolved in a solvent, dichloroethane or the dichloroethane solution, either both or one of them. The method of the invention has the advantages of simple operation, stable process, strong safety, and continuous and stable production. The synthesized diquat dichloride is in a flake structure, which can effectively avoid dust and is helpful for the production and packaging of various pesticide formulations. The method of the invention uses a surfactant, which effectively avoids the agglomeration phenomenon of diquat dichloride.

The present invention discloses a non-bipyridyl salt herbicide and its preparation method and application, specifically, the present invention provides a dienediamine compound having the structure of Formula I or a tricyclodienepiperazine structure shown in Formula II. The non-bipyridyl salt compound can be converted to paraquat or diquat under light irradiation and air conditions, and has the same herbicidal performance as paraquat or diquat but no obvious toxicity. Therefore, the non-bipyridyl salt compound of the present invention can be used as a non-toxic substitute for paraquat or diquat as a herbicide.

The invention relates to an aquacide microsphere preparation and a preparation method thereof, aquacide is entrapped in a polylactic acid-glycolic acid copolymer carrier through a W / O / W type re-emulsification-solvent evaporation method, the microsphere preparation is prepared, slow and continuous release of drugs can be realized, the lasting period is prolonged, the drug application frequency is reduced, and the drug wastage rate and the environmental risk are reduced; meanwhile, the pesticide is in a solid state, is suitable for long-distance transportation, can be redissolved before being used, and has important practical application and commercial values.

The present invention belongs to the field of prognosis of pesticide poisoning. Specifically disclosed is a method for establishing a mortality risk prediction index for acute diquat pesticide poisoning, comprising: collecting data; establishing a mortality risk index model based on demographic characteristics and routine blood test results; and training, internally validating, and externally validating the model. The mortality risk index provided by the present invention comprehensively considers age, blood concentration of diquat, white blood cell count, and aspartate aminotransferase concentration, aiming to accurately evaluate, in the form of an index, the mortality risk of patients suffering from acute diquat pesticide poisoning. Through in-depth analysis of large-scale clinical data, the mortality risk index of the present invention possesses scientific validity and accuracy at the data level, and can also play an important role in clinical practice. Further, the present invention can be applied to construct a terminal device for predicting the mortality risk of acute diquat pesticide poisoning, assisting medical teams in more reasonably allocating medical resources and prioritizing high-risk patients, thereby improving overall treatment outcomes and the patients' chances of survival.

This invention belongs to the field of fine chemicals and discloses a method for preparing dichlorvos. The method includes: reacting 2,2'-bipyridine with a haloalcohol compound of formula I to generate a bipyridine monosalt compound of formula I; after the reaction, separating the bipyridine monosalt compound from the haloalcohol compound; using water as the reaction solvent, reacting the bipyridine monosalt compound with a hydrohalic acid under the action of a catalyst to obtain a reaction solution containing dichlorvos; adjusting the pH of the reaction solution to 4-6 to obtain a dichlorvos solution. This invention provides a novel method for preparing dichlorvos, with a simple synthetic route, high overall yield, lower total cost, and less waste generation, making it more environmentally friendly.

The present invention discloses a method for synthesizing diquat dichloride, comprising: using an alcohol solvent as a reaction solvent, reacting pyridine and dichloroethane in the presence of a catalyst A to generate a quaternary pyridinium ammonium salt; adding water after the reaction, cooling to room temperature, separating the liquids, and removing the alcohol solvent from the aqueous phase under reduced pressure to obtain an aqueous phase containing the quaternary pyridinium ammonium salt represented by Formula II; adding a catalyst B and a ligand to the aqueous phase containing the quaternary pyridinium ammonium salt, performing a coupling reaction to generate a crude diquat dichloride; filtering the reaction solution, distilling the filtrate under reduced pressure until the diquat dichloride is precipitated, cooling the filtrate to room temperature for crystallization, and filtering to obtain a refined diquat dichloride. The method is simple to operate and reduces the complexity of post-processing; and the second step uses water as a solvent, which is environmentally friendly and greatly reduces the generation of "three wastes". The method significantly reduces the production cost of diquat dichloride and has high industrial application value.

The invention discloses a method for preparing diquat dichloride dry powder, and belongs to the field of preparation of agricultural chemicals. According to the method, a high-purity pyridine derivative is selected as a raw material, drying pretreatment is performed under inert gas shielding, a composite catalyst based on MOF derivation is matched, and a reaction is performed under specific reaction conditions. And after the reaction is finished, removing the solvent through reduced pressure distillation, converting a crude product solution into dry powder by adopting an innovative multi-stage cyclone spray drying method, and carrying out strict quality detection on the dry powder. According to the method, the preparation process is remarkably simplified, the cost is effectively reduced, the product quality and stability are greatly improved, the use convenience is greatly improved, and a high-quality diquat dichloride dry powder product is provided for agricultural production.

The present invention belongs to the field of chemical detection technology, specifically a diquat detection kit, including a medicine container and a reaction container, the medicine container includes a double-position protective shell, the top of the double-position protective shell is plugged with a threaded top cover, symmetrical threaded notches are provided on both sides of the inner cavity of the threaded top cover, and test tube containers are symmetrically arranged on the front and back sides of the inner wall of the double-position protective shell, and a control device is arranged on the top of the test tube container, and the test tube container includes a long tube, and the bottom of the inner wall of the long tube is fixedly connected with a medicine barrel. The device can be used for semi-quantitative detection of urine of patients poisoned by bipyridine herbicides, and the detection speed is fast, and the identification of diquat poisoning can be completed within tens of seconds; it can provide a basis for diagnosis, implement targeted rescue measures as soon as possible, and buy precious time for improving the patient's recovery; the overall design is simple, the operation steps are simple, and it is easy to master; the product is small in size and easy to transport and store.

The application discloses a method for determining quaternary ammonium salt pesticides in blood by using liquid chromatography mass spectrometry, which draws a standard working curve of whole blood (plasma, serum) matrix by liquid chromatography mass spectrometry analysis, obtains peak areas of target quantitative ion peaks and peak areas of internal standard quantitative ion peaks of different concentrations of paraquat, diquat, wild wheat, chlormequat, and mepiquat, and then draws a standard working curve; and under the same conditions, liquid chromatography mass spectrometry analysis is carried out on whole blood sample liquid, peak areas of target quantitative ion peaks and peak areas of internal standard quantitative ion peaks in the whole blood sample liquid are obtained at the same time, and the content of each quaternary ammonium salt pesticide is calculated according to the standard working curve. The application can simply, quickly and simultaneously detect the content of five kinds of quaternary ammonium salt pesticides in whole blood of poisoned patients, and has the characteristics of simplicity, accuracy, good repeatability and high sensitivity.

The application provides a hybridoma cell strain secreting monoclone antibody of diquat and application thereof, and relates to the technical field of immune detection. The monoclone antibody secreted by the hybridoma cell strain has good sensitivity to diquat, the IC 50 1.13 ng / mL, so that the monoclone antibody can detect trace diquat. In addition, the monoclone antibody has no cross reaction to structural analogs of diquat, such as alachlor, acetochlor, butachlor, propanil, diquat and diquat, so that the monoclone antibody can accurately detect low concentration diquat.

The present invention provides a fluorescence detection method for bipyridine compounds. This method utilizes sulfonic acid groups and biphenyl structures on the surface of DSD acid-functionalized carbon quantum dots as recognition elements, enabling the DSD acid-functionalized carbon quantum dots to generate electrostatic and π-π interactions with compounds containing bipyridine structures. This static quenching mechanism quenches the fluorescence of the DSD acid-functionalized carbon quantum dots, thereby enabling the DSD acid-functionalized carbon quantum dots to act as a highly sensitive fluorescence sensor for detecting bipyridine compounds. Given the significant difference in binding ability between paraquat and DSD acid-functionalized carbon quantum dots in their excited and ground states, while no significant difference exists for diquat, the present fluorescence detection method can also be used to detect the presence of paraquat in diquat herbicide samples.

The present application relates to the technical field of agricultural product quality improvement, and specifically provides a method for improving the content of tocopherol in sesame by using diquat. It is found for the first time that diquat can improve the content of tocopherol in sesame. The method provided by the present application comprises: spraying a diquat solution 5-15 days before the harvesting of sesame; the diquat solution is a 20% diquat water agent with a volume percentage concentration of 0.167%-0.5%, and the spraying amount of the diquat solution is 10-30 L per mu. The present application provides a reference for improving the content of tocopherol in sesame in production and technical support for the creation of high-quality edible vegetable oil.

The present application belongs to the field of pesticides, and particularly relates to a herbicidal composition containing R-type pyridyloxy carboxylic acid derivatives and application thereof. The herbicidal composition comprises a herbicidal effective amount of active ingredient A and active ingredient B, wherein the active ingredient A is selected from one or more of R-type pyridyloxy carboxylic acids and salt, ester derivatives thereof as shown in formula I: wherein R1 and R2 independently represent halogen, C1-C6 alkyl, halogenated C1-C6 alkyl, C3-C6 cycloalkyl; R3 represents hydrogen, halogen, C1-C6 alkyl, halogenated C1-C6 alkyl; Q represents C1-C6 alkyl, etc.; Y represents amino, etc. The active ingredient B is selected from one or more of glyphosate, glufosinate-ammonium, endothall, paraquat or acid / salt thereof. The composition can effectively prevent various weed problems in crop fields, has the characteristics of expanding the herbicidal spectrum, reducing the application amount, being able to produce a synergistic effect and solving the problem of resistant weeds, etc.

The invention belongs to the technical field of biology, and particularly relates to an in-vivo trapping agent for diquat molecules and a preparation method and application thereof.The in-vivo trapping agent O-TCP (at) M is obtained by synthesizing carboxymethyl alpha-cyclodextrin, constructing rotaxane, preparing a crosslinked polyethyleneimine encapsulated rotaxane compound and finally using macrophages for loading. The carboxymethyl alpha-cyclodextrin highly matched with the aquacide molecular structure is utilized to realize accurate recognition and combination of toxin molecules, and the TK-PEI dendrimer with positive electricity is used for wrapping, so that the structural stability and ROS responsiveness are enhanced. The in-vivo accurate capture and inflammation regulation effects are achieved, poisoning symptoms are relieved, and kidney functions are protected and tissue damage is reduced by accurately capturing and neutralizing toxins.

The present application relates to the field of biotechnology, in particular to an antibody against diquat and application thereof. The present application overcomes technical barriers, and a new hapten molecule is used to prepare an antibody with high affinity to diquat, and cross interference with non-selective herbicides such as paraquat, glufosinate-ammonium and glyphosate with similar structures to diquat can be avoided, which has great significance for the immune detection of diquat.

The invention relates to the technical field of pharmaceutical preparations, in particular to a bionic nano preparation applied to acute diquat poisoning as well as a preparation method and application of the bionic nano preparation. The bionic nano preparation is formed by loading epigallocatechin gallate nano particles on PVA-PLGA (Polyvinyl Acetate-Poly (Lactic-co-Glycolic Acid) nano particles wrapped by an erythrocyte membrane. The bionic nano preparation with a three-layer composite structure is achieved, the purpose of nano preparation escape immune recognition is achieved, and meanwhile the anti-oxidation effect of the medicine is achieved. The preparation method is simple and easy to implement, conditions are controllable, good repeatability is achieved, and the stability of the epigallocatechin gallate can be improved. The prepared erythrocyte membrane bionic EGCG nano preparation has good stability and solubility and can be stored at-20 DEG C for a long time, and the storage life and the service life of the product are prolonged. The nano preparation shows a better diquat detoxification effect, and provides a new drug choice for diquat detoxification.

The application provides a kind of SSZ-112 zeolite molecular sieve and its preparation method and application, it is related to the technical field of molecular sieve.The SSZ-112 zeolite molecular sieve (AFT topology) synthesized by the new double organic template system of Et6-diquat-n dibromide (n=2~10) and bromo 1-propyl-1-methyl pyrrole as organic template agent has high crystallinity, and no amorphous.The SSZ-112 zeolite molecular sieve prepared by the application has excellent carbon dioxide selective adsorption separation performance, and has a broad prospect in the field of flue gas carbon dioxide capture application.Meanwhile, the SSZ-112 zeolite molecular sieve prepared by the application also has excellent catalytic performance in the field of denitration catalysis.

The invention relates to the technical field of pesticides, in particular to a soluble concentrate containing aquacide dichloride and refined glufosinate ammonium and a preparation method of the soluble concentrate. The herbicide comprises the following components: diquat dichloride, refined glufosinate ammonium, a dispersing agent and water, the dispersing agent comprises a plant alkyl betaine mixture and alkylamine polyoxyethylene ether quaternary ammonium salt. The dispersing agent comprises a plant alkyl betaine mixture and alkylamine polyoxyethylene ether quaternary ammonium salt, and can improve the normal temperature stability of the soluble concentrate of diquat dichloride and refined glufosinate ammonium salt; the weight ratio of the alkylamine polyoxyethylene ether quaternary ammonium salt to the plant alkyl betaine mixture is 1: (2-5), so that the low-temperature and high-temperature storage stability of the soluble concentrate can be further improved.

The invention provides a quantitative / semi-quantitative detection method of paraquat or diquat and application, and relates to the technical field of analysis and detection. The quantitative detection method comprises the following steps: adding a reducing sugar solution and an alkaline buffer solution into a to-be-detected sample, uniformly mixing, determining an absorbance value by using a microplate reader, and calculating according to a standard curve to obtain the concentration of paraquat or diquat so as to realize quantitative detection of paraquat or diquat, in addition, semi-quantitative detection can be realized by a colorimetric method after a reducing sugar solution and an alkaline solution are added. Compared with a quantitative or semi-quantitative method in the prior art, the technical scheme provided by the invention is safer and more economical, has the characteristics of simplicity in operation, high analysis speed, stable solution color development and high clinical accessibility, and is beneficial to batch comparison of samples collected at different time points; environment detection of paraquat or diquat and rapid and real-time detection of blood and urine samples of poisoned patients are realized.

The application discloses a kind of Au@4-MBA@Ag surface-enhanced Raman probe preparation methods, belong to nanomaterial and spectroscopic detection technical field.The probe is Au nanoparticle as core, 4-mercapto benzoic acid as intermediate layer, outside coating Ag shell, through the Au-S bond of 4-MBA is fixed in gold core, carboxyl induces Ag+ Coordination deposition, realize Ag shell controllable growth, form core-shell structure.Preparation contains Au nanoparticle, Au@4-MBA nanoparticle, Au@4-MBA@Ag probe three-step core technology, reaction condition is mild, process is easy to control.The probe uses Ag shell plasmon resonance to form electromagnetic enhancement zone, combined with the adsorption enrichment effect of 4-MBA, realize trace detection of paraquat, diquat and its free radical such as dipyridyl herbicide, with high sensitivity, high selectivity and good repeatability, detection limit is low and the requirement of sample pretreatment is low, can also be extended to other pesticide and pollutant detection, suitable for environmental and food safety on-site rapid detection.

The invention discloses diquat dichloride preparation, crystallization and separation equipment and a separation method, and relates to the field of diquat dichloride filtration, the diquat dichloride preparation, crystallization and separation equipment comprises an outer cylinder, a filter cylinder is coaxially fixed to an inner cylinder of the outer cylinder, a separation gap is formed between the outer cylinder and the filter cylinder, the outer cylinder is connected with a feeding port, the feeding port is used for conveying materials into the separation gap, and a discharging port is formed in the bottom of the filter cylinder; the filter cartridge is provided with a discharge port, the discharge port is connected with a negative pressure pump, the negative pressure pump sucks the discharge port to generate negative pressure in the filter cartridge, liquid materials in the separation gap penetrate through the filter cartridge and then are discharged from the discharge port, particle materials are retained in the separation gap, and a spiral plate is arranged in the separation gap. While filtering, the rotating spiral plate is used for scraping diquat dichloride particles adsorbed on the surface of the filter cartridge and conducting and collecting the diquat dichloride particles upwards, so that the filter cartridge is kept to have good permeability, and efficient continuous crystallization and separation work of the diquat dichloride particles is realized.

This invention belongs to the field of biotechnology and specifically relates to an in vivo capture agent for diquat molecules, as well as its preparation method and application. The invention synthesizes carboxymethyl α-cyclodextrin, constructs a rotaxane, prepares a cross-linked polyethyleneimine-encapsulated rotaxane complex, and finally uses macrophages for loading to obtain the in vivo capture agent O-TCP@M. The invention utilizes carboxymethyl α-cyclodextrin, which is highly structurally compatible with diquat, to achieve precise recognition and binding of toxin molecules. The positively charged TK-PEI dendrimers are then used for encapsulation, enhancing structural stability and ROS responsiveness. This invention achieves precise in vivo capture and inflammation regulation, alleviating poisoning symptoms while also protecting kidney function and reducing tissue damage by precisely capturing and neutralizing toxins.

The present invention discloses a non-bipyridyl salt herbicide, its preparation method, and application. Specifically, the present invention provides a diene diamine compound having a structure of Formula I or a tricyclic diene piperazine structure of Formula II. The non-bipyridyl salt compound can be converted into paraquat or diquat under light and air conditions, exhibiting comparable herbicidal properties to paraquat or diquat without significant toxicity. Therefore, the non-bipyridyl salt compound of the present invention can serve as a non-toxic alternative to paraquat or diquat as a herbicide. #imgabs0#

According to the aquacide dichloride soluble concentrate provided by the invention, by reasonably selecting the variety and content of auxiliaries, the stability of a product is improved, the cold storage stability and the heat storage stability are good, the uniform state can be kept in different temperature environments, the problems of layering, crystallization / precipitation and the like are not prone to occurring, and the aquacide dichloride soluble concentrate can adapt to high-hardness water dilution. The preparation method of the aquacide dichloride soluble concentrate is simple and easy to operate, the production cost is low, and through strict quality control indexes, the impurity content in the product is effectively reduced, and the pollution to the environment is reduced. The aquacide dichloride soluble concentrate disclosed by the invention is mainly used for preventing and controlling weeds in uncultivated areas, can be quickly absorbed by green tissues of the weeds, is high in weeding speed and good in effect, has small influence on non-target organisms under a specified dosage, and meets the requirements of environmental protection and safety.