The invention provides a nano-ferroferric oxide sol-gel method production process which adopts ferrous chloride, ferric chloride, ammonia water and oleic acid as main raw materials to synthesis of nano-ferroferric oxide, and adopts the oleic acid to carrying out modification. The method provided by the present invention has advantages of simple experiment equipment, convenient operation and large output. The nano-ferroferric oxide provided by the present invention has characteristics of uniform particle size, good dispersity, stable magnetism, a mean diameter of 15 nm, a saturation magnetization of 55 emu/g. In addition, due to presenting the superparamagnetic, the nano-ferroferric oxide materials can be applicable for a plurality of fields such as chemical engineering, machinery, electronic industry, printing, medicine and the like; meanwhile, due to remarkable magnetic susceptibility and gas and humidity sensing properties, the nano-ferroferric oxide provides great application prospects for a plurality of the fields such as high-density magnetic recording materials, air and humidity sensor parts, magnetic separation of immune cells, magnetic resonance imaging, drug controlled release and the like.