The present invention discloses a pumpkin residue feed for promoting shrimp growth, and a preparation method thereof, wherein the raw materials comprise, by weight, 250-280 parts of pumpkin residue, 2-3 parts of zanthoxylum bungeanum shell, 15-16 parts of phaseolus coccineus, 10-12 parts of ivy mosses, 15-18 parts of black rice, 3-4 parts of marinating water, 2-3 parts of radish leaf, 2-3 parts of caulis polygoni multiflori, 1-2 parts of bamboo shoot, 17-19 parts of earthworm powder, 13-16 parts of wheat bran, 7-9 parts of tomato residue, 0.3-0.5 part of baker's yeast, 15-17 parts of soybean protein powder, 3-5 parts of sesame skin, 2-3 parts of selaginella doederleinii powder, 1-2 parts of angelica powder, and 1-2 parts of dictyophora indusiata powder. According to the present invention, the pumpkin residue feed has characteristics of aroma, feeding attraction, good palatability, shrimp growth and development promoting, nutrition absorption and utilization enhancing, shrimp protein synthesis promoting, shrimp growth and weight gain promoting, feed digestibility improving, material consumption reducing, and feed cost reducing.