32 results about "Copper Chelation" patented technology

The present invention relates to a structure and a method for selectively forming a compact and precise metal pattern on a plastic substrate surface. The structure comprises three layers of materials such as a plastic substrate, nickel or zinc or an indium tin oxide material, and a metal subsequently deposited on the material, wherein the nickel or the zinc or the indium tin oxide material is formed through adopting laser to irradiate the plastic substrate, decomposing an additive previously added to the plastic, and adopting reductive chemical plating to treat. The manufacturing method comprises: adopting laser to selectively scan the plastic substrate. According to the present invention, the additive does not adopt a copper-containing oxide, a copper chelate, a copper complex and a metal oxide having a spinel structure, and adopts the environmentally friendly non-toxic inorganic salt containing nickel and zinc, and the indium tin oxide material, the coupling agent is adopted to carry out coating modification to prepare the additive having a core-shell structure, and the additive is added to the plastic to prepare the laser composite plastic; the laser is adopted to decompose the shell part of the additive so as to release active ingredients in the core; the present invention belongs to a new material based advanced assembly and manufacturing technology in the field of electronic and electric apparatuses; and the structure and the method are used for manufacturing mobile phone antennas, transparent lamp parts, automobile parts, three-dimensional circuits and other products.

The invention discloses a chelated compound trace element fertilizer and a preparation method thereof. The chelated compound trace element fertilizer comprises the following components: EDTA (ethylene diamine tetraacetic acid) chelated copper, EDTA chelated zinc, EDTA chelated iron, EDTA chelated manganese, borax decahydrate and ammonium molybdate. The preparation method comprises the steps of preparing EDTA chelated copper, EDTA chelated zinc, EDTA chelated iron and EDTA chelated manganese; purchasing borax decahydrate and ammonium molybdate; mixing the raw materials, drying, grinding and packaging to obtain a finished product. The prepared trace element fertilizer can be sprayed or flushed, and has a good effect on improving the symptoms such as small leaves, yellow leaves, undergrowth and the like of vegetables caused by deficiency of trace elements.

The invention provides a preparation production method of a composite peptide-copper chelate by utilizing a meat processing byproduct and a corresponding product composite peptide-copper chelate. The preparation method of the composite peptide-copper chelate comprises the following steps: carrying out enzymolysis on the meat processing byproduct (blood powder, feather meal and the like) with proteolytic enzyme in a certain condition to obtain enzymatic hydrolysate with small peptide as a main component; carrying out a chelation reaction on a copper salt solution and the enzymatic hydrolysate serving as ligand, and controlling the temperature, pH and reaction time of a reaction system so as to prepare a better chelated product through a two-step chelation reaction by adopting a method of determining a charge rate according to the copper ion coordination characteristics and small peptide detection result for the first time. The product composite peptide-copper chelate can be effectively absorbed by animals including ruminant, livestock and aquatic animals, so that the application range of byproducts can be enlarged, and the utilization rate of the byproducts can be improved. The preparation method is less in investment, and is easy to produce on large scale.

The invention discloses chelate resin, a preparation method of the chelate resin and application of the chelate resin in nickel-copper containing solution deep copper removal. The chelate resin is grafted with a 2-amino methyl pyridine functional group containing a tertiary amine group and an ester group at the same time; the functional group only causes physical absorption with nickel (II) and causes a chemical chelation effect with copper (II), special functions of the functional group are sufficiently utilized and grafted to matrixes such as silica gel and polystyrene, a series of chelate resin is obtained, the chelate resin reserves special selective copper chelation function of the functional group, can be easily separated from a solution, can be applied in selectively removing copper in the nickel-copper containing solution and is particularly applicable to high-selectivity deep-purification copper removal of nickel anodic electrolyte in a chloride system and a chloride-sulfate mixed system, and the copper content in the solution with copper removed and the copper-nickel mass ratio of the desorbed solution can both meet industrial requirement for deeply removing copper through nickel anodic electrolyte.

The invention discloses a method for separating copper proteome by using copper-chelated magnetic beads, and relates to the technical field of protein chemistry. The method comprises the following steps: taking a biological tissue or cell, after fully grinding with liquid nitrogen, adding protein extracting liquid, and after uniformly mixing, carrying out low-temperature centrifugation, so as to obtain a denatured protein solution; mixing the copper-chelated magnetic beads with the denatured protein solution, and incubating to obtain a magnetic bead protein mixed solution; adding a buffer solution 1 with the volume 1 time of that of the magnetic bead protein mixed solution into the magnetic bead protein mixed solution for suspension, pouring half of the supernate under the external magnetic field, and repeating for 4-5 times to obtain a mixed solution A; adding a buffer solution 2 with the volume 1 time of that of the mixed solution A into the mixed solution A, separating all the specific copper-binding proteins, namely, the copper proteome, and collecting the copper proteome under the external magnetic field. According to the method, the metalloproteome is separated under a denaturing condition by using magnetic bead-IDA, so that the procedures are greatly simplified, and the obtaining efficiency of metalloproteins is improved; a method suitable for separating the metalloproteome from the tissue or cell under the excess heavy metal treatment condition is established.

The invention provides magnetic copper (II) chelating ferroferric oxide @carbon nanoparticles and a preparation method thereof, and a method for immobilizing laccase. The preparation method comprisesthe steps of firstly preparing hydroxyl / carboxyl functionalized magnetic Fe3O4@C nanoparticles by a hydrothermal method, then performing coordination adsorption on Cu2+ ions to obtain magnetic Cu(II)chelating Fe3O4@C nanoparticles, and finally through the coordination effects of laccase histidine residues and Cu(II), preparing magnetic Cu(II) chelating Fe3O4@C nanoparticle immobilized laccase which is high in stability, high in activity and reusable. Compared with the prior art, the prepared magnetic Cu(II) chelating Fe3O4@C nanoparticle immobilized laccase is simple to operate, economic andenvironmentally-friendly; and the enzyme loading quantity is high, immobilized laccase is high in catalytic activity and high in stability, can be simply cycled and reused, and has great application prospects, and actual production cost can be effectively reduced.

The invention provides a preparation method of marine biological protein peptide copper chelate. The method comprises the following specific steps of: carrying out enzymolysis on sea fish processing leftovers through alkaline compound protease, and carrying out centrifugal filtration to obtain protein peptide solution; adjusting the pH value of the protein peptide solution, and adding soluble copper salt to carry out chelation reaction; and after the chelation reaction is finished, removing free copper ions in the obtained reaction solution through a nano-filtration system, carrying out triple-effect concentration on the filtrate, and carrying out high-temperature spray drying to obtain the marine biological protein peptide copper chelate. The prepared marine biological protein peptide copper chelate is high in copper chelation rate, and can remarkably strength the enzyme activity in the animals and improve the utilization rate of protein, fat and vitamins after being added into feeds, so as to improve the growth performance of the animals.

The invention discloses a long-acting total-nutrient wheat special-purpose fertilizer suitable for straw turnover. The long-acting total-nutrient wheat special-purpose fertilizer suitable for straw turnover is composed of, by weight, 400 to 550 parts of urea, 150 to 300 parts of potassium chloride, 200 to 300 parts of monoammonium phosphate, 1 to 10 parts of inhibitor NAM, 1 to 10 parts of boric acid, 1 to 10 parts of EDTA chelated zinc, 1 to 10 parts of EDTA chelated copper, 1 to 10 parts of EDTA chelated manganese, 1 to 10 parts of EDTA chelated iron, 0.1 to 0.4 part of ammonium heptamolybdate, and 0.1 to 0.4 part of a bacterial preparation. The long-acting total-nutrient wheat special-purpose fertilizer possesses following advantages: 1, the appearance is smooth, caking is not easily caused; 2, nutrient combination is balance, and stable; 3, fertilizer effect lasts long, utilization rate is high, labor intensity is reduced, and environment pollution is reduced; 4, nutrients are comprehensive; and 5, the bacterial preparation is contained.

The invention discloses a fertilizer special for urea-ammonium nitrate liquid spray and drop irrigation crops and belongs to the technical field of fertilizers special for liquid spray and drop irrigation crops.The fertilizer is prepared from a urea-ammonium nitrate solution, monoammonium phosphate, potassium carbonate, citric acid chelated copper, EDTA chelated zinc, borax, potassium fulvic, sodium carboxymethyl cellulose and water.Compared with an existing technology, the fertilizer has the advantage of low cost, comprehensive nutrients and high fertilizer utilization rate.

The present invention relates to the discovery that non-traditional export of certain pro-inflammatory cytokines lacking a signal sequence from a cell can be inhibited by copper chelation and / or administration to the cell of a truncated form of S100A13 lacking the basic residue portion. Further, copper chelation inhibits, inter alia, neointima formation, macrophage infiltration and associated inflammation, cell proliferation, secretion of extracellular matrix, intimal thickening, adventitial angiogenesis, restenosis, and the like, associated with vascular vessel injury. Thus, the present invention provides novel methods of preventing and treating, and for identifying novel compounds also useful as therapeutics for, such conditions.

The present invention relates to the discovery that non-traditional export of certain pro-inflammatory cytokines lacking a signal sequence from a cell can be inhibited by copper chelation and / or administration to the cell of a truncated form of S100A13 lacking the basic residue portion. Further, copper chelation inhibits, inter alia, neointima formation, macrophage infiltration and associated inflammation, cell proliferation, secretion of extracellular matrix, intimal thickening, adventitial angiogenesis, restenosis, and the like, associated with vascular vessel injury. Thus, the present invention provides novel methods of preventing and treating, and for identifying novel compounds also useful as therapeutics for, such conditions.

The invention relates to the technical field of organic chemical synthesis, in particular to a preparation method of L-theanine. The preparation method of the L-theanine comprises the following steps:(a) reacting L-glutamic acid with a copper salt in a solvent to obtain a chelate A; (b) carrying out an esterification reaction on the chelate A and methanol to obtain a compound B; and (c) after a reaction of the compound B with an aqueous ethylamine solution is finished, adding a decoppering reagent, carrying out stirring for a reaction, and removing a solvent to obtain a crude L-theanine product. According to the preparation method of the L-theanine, the L-glutamic acid is used as an initial raw material and is easy to obtain; in addition, residues in amino acid are protected by adopting acopper chelate manner, so the reaction process is green and environment-friendly. In the step (c), the safer aqueous ethylamine solution is used for the reaction, so the safety of the reaction is improved, requirements on equipment are reduced, production cost is greatly saved, and industrial production is easier.

The embodiment of the invention provides a double-sided intravascular stent with a nitric oxide catalytic release function and a preparation method of the double-sided intravascular stent, and relates to the field of cardiovascular interventional therapy instruments. The double-sided intravascular stent comprises a stent body, the inner wall of the stent body is coated with an adhesion layer, a bionic pattern structure is carved on the outer wall of the stent body, and active drugs are arranged in the bionic pattern structure; the adhesion layer contains primary amino and o-phenolic hydroxyl, and the surface, away from the stent body, of the adhesion layer is grafted with a Cu chelate. The adhesion layer of the double-sided intravascular stent takes surface primary amino as a reaction site, copper chelate can be covalently grafted to catalyze release of NO based on carbodiimide chemical cross-linking reaction, a bionic pattern structure is engraved and constructed on the outer surface of the stent body through a laser technology, and a bioactive medicine with a complementary function with NO is loaded, so that the double-sided intravascular stent is prepared. NO can be stably released through synergistic cooperation of the inner surface and the outer surface of the stent body, and the functions of synergistic anticoagulation, anti-inflammation and diseased vascular tissue regeneration and repair promotion of the double-sided modified coating are creatively exerted.

The invention discloses a chelated compound trace element fertilizer and a preparation method thereof. The chelated compound trace element fertilizer comprises the following components: EDTA chelated copper, EDTA chelated zinc, EDTA chelated iron, EDTA chelated Manganese, borax decahydrate and ammonium molybdate; Its preparation method comprises: the preparation of EDTA chelated copper, EDTA chelated zinc, EDTA chelated iron and EDTA chelated manganese, borax decahydrate and ammonium molybdate are purchased, and above-mentioned The raw materials are mixed, dried, pulverized and packaged to make finished products. The prepared trace element fertilizer can be sprayed or flushed, and has a good effect on improving various symptoms such as small leaves, yellow leaves, and poor growth of vegetables caused by the lack of trace elements.

The invention discloses a special high photosynthetic efficiency formula fertilizer for fusant pelleting corn and a preparation method of the special high photosynthetic efficiency formula fertilizer and belongs to the field of production technologies of crop special fertilizers. The special high photosynthetic efficiency formula fertilizer is prepared from the follow raw materials: urea, monoammonium phosphate, potassium chloride, anhydrous magnesium sulfate, borax, EDTA chelate iron, EDTA chelate copper and EDTA chelate zinc. The formula fertilizer is mainly applied in corn seeding period and big bellmouthed period, the efficiency for solar energy utilization of corn can be obviously improved, photosynthesis of the corn can be promoted, and then accumulation of organic matters is increased so as to finally achieve the effect of increasing both production and income.

The invention discloses a multifunctional tree infusion liquid based on water bloom algae utilization and a preparation method thereof. The multifunctional tree infusion liquid is composed of a main nutrient solution and an auxiliary nutrient solution according to a ratio of 1000 ml: 10 ml. The main nutrient solution contains a water bloom algae extracting solution, a stress-resistant osmotic adjusting substance, superoxide dismutase, catalase, peroxidase, antibiotics, chelated calcium, chelated iron, chelated manganese, chelated zinc, chelated copper, chelated boron, chelated molybdenum, abscisic acid and the balance of purified water, and the total volume is 1000ml; the auxiliary nutrient solution contains potassium chloride, chelated magnesium and the balance of purified water, and the total volume is 10ml. The invention can provide the tree infusion liquid which is wide in source, environment-friendly in production process and closer to nutritional ingredients in a tree body, so that the tree nutrition can be efficiently supplemented, the physiology of the tree can be regulated, and the stress resistance of the tree can be improved.

The invention provides mesotrione copper chelate form I and mesotrione copper chelate form II. A process for preparing mesotrione copper chelate form I and mesotrione copper chelate form II is also disclosed. Further, the present invention provides process for preparing mesotrione metal chelate polymorphs and agrochemical formulations comprising such polymorphs.

The invention discloses a preparation method of copper glycinate chelate, is used for improving a drying method of the copper glycinate chelate and belongs to the technical field of trace element fertilizers. The preparation method of the copper glycinate chelate comprises the following steps: dissolving glycine in distilled water, adding a copper salt and a catalyst, reacting at 35-60 DEG C for 0.8-1.2 h, performing cooling crystallization, separating the crystal to obtain a crystal solid, removing impurities, sending the crystal solid into a rotary flash evaporation drying tower for drying,and carrying out microwave drying to finally obtain the copper glycinate chelate. According to the invention, the rotary flash evaporation drying tower and the microwave drying are combined, so that the copper glycinate chelate is dispersed and crushed and the uniformity and dispersity of product particles are improved; the method can also act inside copper glycinate chelate particles, quickly removes water and redundant crystal water which are not diffused inside, greatly shortens the drying time, improves the drying efficiency, enables the product to be low in moisture content, good in dispersity, loose and not prone to caking, and improves the product quality.

The invention relates to a preparation method of geniposide food antiseptic and fresh-keeping materials. The method uses geniposide and copper sulfate as raw materials, that is, the copper sulfate solution is added dropwise to the geniposide solution, stirred while dropping, and the dropping is completed After that, let it cool and stand still, then take the supernatant and pass it through a silica gel column for purification, and the purified solution that flows out is concentrated and crystallized in a vacuum, and dried to obtain the finished geniposide food antiseptic and fresh-keeping material geniposide-copper (II) chelate. The present invention has the advantages: 1. Applying geniposide to the field of antiseptic and fresh-keeping of food expands the scope of use of geniposide, directly consumes more gardenia raw materials for agricultural materials, increases market demand for gardenia, and benefits gardenia sub-planter. 2. The geniposide food antiseptic and fresh-keeping material prepared by the method of the present invention can not only preserve food anti-corrosion and prolong the shelf life of food, but also meet the human body's demand for trace element copper.

The invention relates to the technical field of feed, in particular to a self-assembled small peptide chelated copper feed additive and a preparation method thereof. The preparation method comprises the following steps: S1, preparing small peptide powder, mixing amino acid and strong acid resin at 70-90 DEG C, stirring for 2-5 hours, removing the strong acid resin, and drying to obtain the small peptide powder; and S2, preparing small peptide chelated copper, dissolving the small peptide powder obtained in the step S1, then adding an inorganic copper solution, reacting for 0.8-2.5 h at the temperature of 60-80 DEG C, concentrating after the reaction, then adding methanol to separate out the small peptide chelated copper, and purifying to obtain the additive. The strong acid resin is adopted as a mold plate and a catalyst, and chelating of the obtained small peptide and inorganic copper is more stable. The obtained small peptide chelated copper compound is good in stability in animal stomachs and more comprehensive in nutrition, and can be used as the feed additive to supplement trace elements of daily ration and improve the immune function and growth speed of animal bodies.

Biocidal materials and methods of forming are provided. The biocidal material includes a carrier and a plurality of treated copper-containing particles, the treated copper-containing particles including a particle surface pretreatment. The surface pretreatment material comprises a copper chelating material.

The invention discloses a preparation method of a cod skin collagen peptide copper chelate. The preparation method is characterized by comprising the following steps of: weighing a certain amount of cod skin collagen peptide and copper sulfate, putting the weighed cod skin collagen peptide and copper sulfate into a beaker, adding 100ml of distilled water, fully mixing and dissolving, and heating in a water bath. The cod skin collagen peptide copper chelate prepared by the method is simple in process method and less in environmental pollution, can obtain good economic and social benefits, and promotes the development of the deep processing industry of marine aquatic products.

The invention relates to a preparation method of a protein peptide copper chelate suitable for ruminants. The method comprises main steps of protein liquid preparation, enzymolysis, ultrafiltration, chelation and spray drying so as to obtain the protein peptide copper chelate. The method takes soybean protein wide in source as a protein peptide source and inorganic copper salt as an iron source, chelates copper element and protein peptide, and is simple in technological process, low in cost and suitable for large-scale industrial production. The product prepared by the method has high contentof micromolecular peptide and high content of chelated copper ion, and is a novel efficient copper supplement agent for feeds.

The invention discloses a plant growth regulator applied to cut dianthus caryophyllus flowers and an application method thereof. The plant growth regulator applied to cut dianthus caryophyllus flowers is composed of a seedling stage dianthus caryophyllus plant growth regulator, a vegetative stage dianthus caryophyllus plant growth regulator and a flowering stage dianthus caryophyllus plant growth regulator. The seedling stage dianthus caryophyllus plant growth regulator contains compound sodium nitrophenolate and a fertilizer, the fertilizer comprises urea, phosphorus pentoxide, potassium oxide, magnesium oxide, borax, EDTA chelated copper, EDTA chelated iron, EDTA chelated zinc and bentonite. The vegetative stage regulator contains DA-6, compound sodium nitrophenolate and the fertilizer. The flowering stage regulator contains DA-6 and the fertilizer. Root-irrigation is adopted for application of the regulators of various stages. The plant growth regulator applied to cut dianthus caryophyllus flowers provided by the invention increases the root length, root fresh weight, stem diameter, leaf number, flower diameter and petal number of dianthus caryophyllus, improves the quality of cut dianthus caryophyllus flowers, and then further strengthens the commodity competitiveness of cut dianthus caryophyllus flowers.

The invention discloses a plant growth regulator applied to cut dianthus caryophyllus flowers and an application method thereof. The plant growth regulator applied to cut dianthus caryophyllus flowers is composed of a seedling stage dianthus caryophyllus plant growth regulator, a vegetative stage dianthus caryophyllus plant growth regulator and a flowering stage dianthus caryophyllus plant growth regulator. The seedling stage dianthus caryophyllus plant growth regulator contains compound sodium nitrophenolate and a fertilizer, the fertilizer comprises urea, phosphorus pentoxide, potassium oxide, magnesium oxide, borax, EDTA chelated copper, EDTA chelated iron, EDTA chelated zinc and bentonite. The vegetative stage regulator contains DA-6, compound sodium nitrophenolate and the fertilizer. The flowering stage regulator contains DA-6 and the fertilizer. Root-irrigation is adopted for application of the regulators of various stages. The plant growth regulator applied to cut dianthus caryophyllus flowers provided by the invention increases the root length, root fresh weight, stem diameter, leaf number, flower diameter and petal number of dianthus caryophyllus, improves the quality of cut dianthus caryophyllus flowers, and then further strengthens the commodity competitiveness of cut dianthus caryophyllus flowers.

The present invention relates to antifouling compositions comprising copper di(ethyl 4,4,4-trifluoroacetoacetate) (Cu(ETFAA)2) that are highly effective against marine biofouling of surfaces of ships and marine structures, their use for inhibiting marine biofouling, as well as antifouling paints comprising said compositions.

The invention provides a preparation method of marine biological protein peptide copper chelate. The method comprises the following specific steps of: carrying out enzymolysis on sea fish processing leftovers through alkaline compound protease, and carrying out centrifugal filtration to obtain protein peptide solution; adjusting the pH value of the protein peptide solution, and adding soluble copper salt to carry out chelation reaction; and after the chelation reaction is finished, removing free copper ions in the obtained reaction solution through a nano-filtration system, carrying out triple-effect concentration on the filtrate, and carrying out high-temperature spray drying to obtain the marine biological protein peptide copper chelate. The prepared marine biological protein peptide copper chelate is high in copper chelation rate, and can remarkably strength the enzyme activity in the animals and improve the utilization rate of protein, fat and vitamins after being added into feeds, so as to improve the growth performance of the animals.

The invention discloses a detecting method for fast identifying copper mothionine chelate and judging the stability of copper mothionine chelate, and relates and belongs to the field of fodder technology detection. The fast judging mode is based on the characteristic of copper mothionine chelat and the gastrointestinal tract environment of an animal. According to the detecting method, the total content of copper and methionine in copper mothionine chelate, the residual quantity of a copper source, the content of copper in a solution in different pH value conditions and the dissolving condition of copper mothionine chelate in pure water are measured, and the quality conditions of copper mothionine chelate produced by different factories are comprehensively compared and judged.

A biocide resin composition that includes one or more solutions of selected melamine-formaldehyde, urea-formaldehyde, phenol-formaldehyde, melamine-urea-formaldehyde, and phenolic resins, and more than one copper salt soluble in aqueous systems and melamine-formaldehyde, urea-formaldehyde, and phenolic solutions. Copper salts are of the copper citrate, copper lysinate, copper gluconate, copper salicylate, copper phthalocyanine, copper chelate, copper oxalate, copper acetate, copper methionine, copper tartrate, copper glycinate, copper picolinate, copper aspartate, ammoniacal copper complexes, EDTA (ethylenediaminetetraacetic acid)-copper complexes, copper glycolate, copper glycerate, copper ascorbate type and, in general, copper salts of the organic type, R—Cu, R1-Cu—R2, where R, R1, and R2 can be alkyl chains (C3-C18) with one or more acid, aldehyde, ester, ether, hydroxyls, amino, or others groups in its structure.