The invention relates to a preparation method of 2-aminobenzimidazole, and belongs to the technical field of compound synthesis. The preparation method comprises the following steps: adding water into a reactor, adding o-phenylenediamine, and uniformly dispersing; slowly adding
guanidine salt, uniformly dispersing, and controlling the temperature of the
system in the feeding process to be not higher than 70 DEG C; and adding alkali liquor to adjust the pH value of the
system to be alkalescent, then heating and carrying out a heat preservation reaction, and after the reaction is finished, carrying out post-treatment to obtain the 2-aminobenzimidazole product. The
guanidine salt is at least one of
guanidine hydrochloride,
guanidine sulfate and
guanidine nitrate. The
molar ratio of the o-phenylenediamine to the guanidine salt is 1: (1.1-1.5). When the o-phenylenediamine and the guanidine salt react, the
reaction temperature is 60-90 DEG C, and the reaction time is 6-10 hours. The preparation method has the advantages of cheap and easily available raw materials, high conversion rate, high atom
utilization rate and better industrial application prospect.