17 results about "Guanidine nitrate" patented technology

The invention relates to the technical field of guanidine nitrate preparation, in particular to a method for preparing guanidine nitrate by a continuous dynamic tubular reaction process, which comprises the following steps: uniformly mixing dicyandiamide, target ammonium nitrate and target ammonium carbonate according to a mass ratio of 1: (1-3): (1-0.5); conveying the uniformly mixed material to a feeding section in a dynamic tubular reactor through a first conveying screw rod for mixing treatment, wherein the dynamic tubular reactor further comprises a heating section, a reaction section and a cooling section; sequentially conveying the target mixed material to a heating section for heating melting treatment, a reaction section for synthesis reaction treatment and a cooling section for cooling forming treatment through a second conveying screw rod to obtain an initial product; conveying the initial product into a cooling and crushing device for cooling and slicing to obtain a target guanidine nitrate product. According to the method disclosed by the invention, the mass and heat transfer efficiency can be improved, the online quantity and liquid holdup of the material are reduced, meanwhile, the raw material ratio and the reaction path are optimized, and the safety and the product purity are improved.

The invention relates to the technical field of pharmaceutical analysis, in particular to a method for detecting the content of guanidine nitrate by precolumn derivatization-high performance liquid chromatography, which comprises the following steps: oscillating and uniformly mixing a guanidine nitrate reference substance or sample and pure water at room temperature, adding sulfuric acid concentrated liquor in cold water bath to perform derivatization reaction, after the reaction is finished, placing at room temperature, and performing column chromatography to obtain the guanidine nitrate content. Adding liquid caustic soda for neutralization, carrying out gradient constant volume by using a mobile phase, and filtering by using a microporous filter membrane to respectively obtain a derivatization reference solution and a derivatization sample solution; and respectively injecting the derivatization reference substance solution and the derivatization sample solution into HPLC, recording peak areas, and calculating the content of guanidine nitrate in the sample by adopting an external standard method. The guanidine nitrate sample is pretreated through the precolumn derivatization reaction, the guanidine nitrate derivative generated through the reaction has the advantages of being high in stability and easy to separate, ammonium nitrate and nitric acid impurities can be effectively prevented from interfering the detection result, the explosive picric acid is not adopted in the detection method, and the detection method is simple, safe and easy to implement.

The invention discloses a method for realizing continuous synthesis and crystallization control of nitroguanidine by using a continuous flow multi-stage stirring reactor. The method comprises the following steps: weighing perfluorinated sulfonic acid resin, placing the perfluorinated sulfonic acid resin in a catalyst cage, and mounting the catalyst cage in the continuous flow multi-stage stirring reactor; setting the temperature of a reaction section to be 20-50 DEG C and the temperature of a crystallization section to be-20-10 DEG C; introducing concentrated sulfuric acid in advance to fill an internal channel of the continuous flow multi-stage stirring reactor; guanidine nitrate and concentrated sulfuric acid are premixed and then introduced into the reactor, and the retention time of a reaction section is 0.5-10 min; water is introduced into the crystallization section, and the standing time in the crystallization section is 1-30 min; and collecting a reaction product solution, washing with cold water, and filtering. The continuous synthesis of the nitroguanidine prepared by the sulfuric acid method is realized, the mass and heat transfer efficiency is greatly improved, the reaction time is greatly shortened, the product yield is greatly improved, and the maximum yield of the nitroguanidine is 98%.

A gas generant composition for passive inflatable restraint systems (e.g., airbags) for automobiles is provided that comprises a melamine oxalate compound. The gas generant may be a cool burning gas generant composition that comprises a melamine oxalate compound, a co-fuel, such as guanidine nitrate, and an oxidizer, such as basic copper nitrate. The gas generant composition has advantageous combustion properties, including a maximum flame temperature at combustion (Tc) of ≤about 1700K (1,427° C.), a linear burn rate of ≥about 18 mm per second at a pressure of about 10 megapascals (MPa), a gas yield of the gas generant composition of ≥about 5.7 moles / 100 cm3, and a linear burn rate pressure exponent of ≤about 0.35.

The invention discloses a method for realizing one-step continuous synthesis and crystallization control of nitroguanidine by acoustic resonance enhancement, which comprises the following steps of: 1, purging the interior of a whole reactor by using inert gas, and introducing concentrated nitric acid and the inert gas in advance; 2, starting an acoustic resonance reaction platform, and adjusting the resonance frequency and the acceleration of the acoustic resonance reaction platform; 3, guanidine nitrate and nitric acid are premixed and then introduced into the continuous reactor, and meanwhile inert gas is controlled to be introduced into the continuous reactor; and 4, collecting a reaction product, washing with cold water, and filtering. According to the method, the mass transfer and heat transfer efficiency is greatly improved, the reaction time is greatly shortened, the product yield is greatly improved, and the highest yield of nitroguanidine is 98%; by adjusting the resonant frequency and the acceleration, the granularity of the product can be accurately controlled, and the granularity requirement of the industry is met.

Gas generating composition for use in safety devices for vehicles, with a gas yield of at least 85%, the composition consisting of 75 to 98 wt% guanidine nitrate as fuel, 2 to 25 wt.% of a combustion accelerator selected from the group of transition metal compounds, metal nitrates, metal chlorates, metal perchlorates, ammonium perchlorate and mixtures thereof, wherein the transition metal compounds are selected from the compounds of the transition metals Ti, Cr, Mn, Fe, Cu, Zn, Zr and Mo and have an average grain size of at most 5 µm and a specific surface area of ​​at least 1 m 2 / g, 0 to 5 wt.% combustion moderators and / or coolants, and 0 to 3 wt.% processing aids from the group of flow aids, pressing aids and lubricants, each based on the total composition, and wherein the gas generating composition has a burning rate of 3 to 17 mm / s at 20 MPa.

The invention relates to the technical field of preparation of fine chemical intermediates, in particular to a method for preparing nitroguanidine by a continuous static tubular reaction process, which comprises the following steps: pumping a sulfuric acid solution in a batching tank into a static tubular reactor; the guanidine nitrate in the feeding hopper is pushed to a static tubular reactor through a solid feeder installed at an output port of the feeding hopper, and the mass ratio of the sulfuric acid solution to the guanidine nitrate is controlled to be 1.0: (1.0-5.0); uniformly mixing a sulfuric acid solution and guanidine nitrate through a high-shear pump, and conveying the mixture to a reaction section of the static tubular reactor for reaction; conveying a reaction product into a hydrolysis kettle, and sequentially carrying out hydrolysis and preliminary cooling treatment; and conveying the initial product into a crystallization mechanism for cooling crystallization, and carrying out filtering centrifugal treatment and drying treatment to obtain a target nitroguanidine product. According to the method, high-efficiency, safe and continuous nitroguanidine production is realized, and the purity and quality of the target product nitroguanidine are also effectively improved.

A method of forming a fuel mixture for a gas generating composition according to various implementations comprises the step of providing a mixture of melamine and water and adding nitric acid to the mixture to form melamine nitrate. Guanidine carbonate is mixed in to form guanidine nitrate. The guanidine carbonate mixing step may be performed at room temperature for at least 10 minutes. The melamine nitrate and guanidine nitrate form a solid precipitate fuel mixture which is filtered and rinsed with water. The rinsed fuel mixture is then dried. The drying step may be performed at a temperature in the range of 100° C. to 110° C. The nitric acid may be added as an aqueous solution having a molarity of 0.1 to 0.25. Also disclosed is a gas generating composition for use in airbag gas generators comprising the melamine nitrate and guanidine nitrate fuel mixture.

The present invention provides a compound, calcium guanidine nitrate, and a birefringent calcium guanidine nitrate crystal, as well as a preparation method and use thereof. The chemical formula of the compound is [C(NH2)3]2Ca(NO3)4(H2O)2, the molecular weight is 444.33, and the compound is prepared by a solvent thermal method. The crystal chemical formula is [C(NH2)3]2Ca(NO3)4(H2O)2, the molecular weight is 444.33, and the crystal belongs to the monoclinic system with a space group of C 2 / c , the unit cell parameters are a =20.319(3)Å, b =6.5717(8)Å, c =14.2195(16)Å, α =90°, β =116.399(5)°, c =90°, the unit cell volume is 1700.8(4)Å 3 , with a transmittance range of 281-1600 nm and a birefringence index between 0.152 (1064 nm) and 0.23 (281 nm). Grown using a room-temperature aqueous solution method, the resulting birefringent crystals possess moderate mechanical hardness, are easily cut, polished, and stored, and are easy to grow under simple growth conditions. They are insoluble in water, non-deliquescent, and stable in air. They exhibit a wide transmittance range and birefringence, and can be used to fabricate polarization beam splitters, phase delay devices, and electro-optical modulators.

The invention provides a high-yield synthesis method of trimethoprim, which comprises the following steps: (a) adding 3-methoxypropionitrile and 3, 4, 5-trimethoxybenzaldehyde into an organic alcohol alkali-organic alcohol solution, heating to 30-45 DEG C, and carrying out condensation reaction; (b) directly decompressing the condensation product obtained in the step (a) to remove most organic alcohol, then adding an alcohol ether solvent and guanidine nitrate, heating to 70-80 DEG C, and reacting until the reaction is finished; and cooling to 0-5 DEG C to obtain a trimethoprim crude product. The trimethoprim with high yield can be obtained only by using a one-pot method without treating an intermediate, so that the process is simple, and the working procedure and the working hour are saved; alcohol ether is used as a solvent in the ring closing step, so that the yield is further improved.

The present disclosure provides a gas-generating agent composition, a gas-generating agent, and a preparation method and the use. The gas-generating agent composition comprises the following components, in percentages by mass: 30-70% of guanidine nitrate, 20-60% of basic copper nitrate, 0-10% of basic copper carbonate, 1-10% of ammonium perchlorate and 1-15% of a slag-forming agent, wherein the slag-forming agent comprises a first component and a second component, the first component being selected from aluminum hydroxide, and the second component being selected from at least one of a zirconate and a silicate.

A filtering device for guanidine nitrate production belongs to the field of devices for guanidine nitrate production and comprises a filtering unit, a collecting unit and a stirring unit, the collecting unit is fixed at the lower end of the filtering unit, and the stirring unit is rotatably connected in the filtering unit. The problems that in the background technology, an existing guanidine nitrate filter needs to be detached after being used and then is cleaned, time and labor are wasted, and the cleaning is not convenient enough are solved.

The invention relates to the technical field of new energy automobile batteries, in particular to a new energy automobile battery heat dissipation device.A fire extinguishing assembly comprises a material box fixed in a heat dissipation bin, sliding grooves are formed in the top and the bottom of the material box, a supporting frame is slidably connected to the interior of the material box along the sliding grooves, and a first air bag is fixed in the supporting frame; the material box is slidably connected with an ejector rod, a conventional magnet is fixed to the end, located outside the material box, of the ejector rod, and in the fire extinguishing state, the second wheel repeatedly rubs with the first wheel to generate high temperature when rotating highly, and the high temperature is transmitted into the material box through a hollow pipe to rapidly preheat guanidine nitrate; according to the preheating purpose, guanidine nitrate can be rapidly heated, oxidized and reduced to generate nitrogen in the battery cell bin, oxygen in air is diluted or exhausted through the nitrogen in the two air bags and the nitrogen generated through guanidine nitrate oxidation and reduction, so that the concentration of oxygen around a battery fire source is reduced, oxygen needed by combustion is insufficient, and flames are extinguished.

The invention relates to a preparation method of 2-aminobenzimidazole, and belongs to the technical field of compound synthesis. The preparation method comprises the following steps: adding water into a reactor, adding o-phenylenediamine, and uniformly dispersing; slowly adding guanidine salt, uniformly dispersing, and controlling the temperature of the system in the feeding process to be not higher than 70 DEG C; and adding alkali liquor to adjust the pH value of the system to be alkalescent, then heating and carrying out a heat preservation reaction, and after the reaction is finished, carrying out post-treatment to obtain the 2-aminobenzimidazole product. The guanidine salt is at least one of guanidine hydrochloride, guanidine sulfate and guanidine nitrate. The molar ratio of the o-phenylenediamine to the guanidine salt is 1: (1.1-1.5). When the o-phenylenediamine and the guanidine salt react, the reaction temperature is 60-90 DEG C, and the reaction time is 6-10 hours. The preparation method has the advantages of cheap and easily available raw materials, high conversion rate, high atom utilization rate and better industrial application prospect.

The present application relates to a kind of 2-amino benzimidazole preparation method, belong to compound synthesis technical field.The preparation method is: in reactor, water is added, and o-phenylenediamine is uniformly dispersed;Then slowly add guanidine salt and uniformly dispersed, control the temperature of system during feeding process not higher than 70 DEG C;Add lye to adjust the pH of system to weak alkaline, then heat and keep warm reaction, after reaction is finished, 2-amino benzimidazole product is obtained after post-processing.The guanidine salt is at least one of guanidine hydrochloride, guanidine sulfate, guanidine nitrate.The molar ratio of o-phenylenediamine used and guanidine salt is 1: (1.1-1.5).When the o-phenylenediamine and guanidine salt react, the reaction temperature is 60-90 DEG C, and the reaction time is 6-10h.The raw material of the preparation method is cheap and easy to obtain, conversion rate is high, atom utilization rate is high, and has better industrial application prospect.

The application belongs to the technical field of disinfection and sterilization of medical systems, and provides a visible light photocatalytic disinfectant for aerosol attached pathogenic bacteria in emergency rooms as well as a preparation method and application thereof. The disinfectant comprises composite nanoparticles of guanidine nitrate C3N4 and deionized water. The non-metallic guanidine nitrate is compounded with the C3N4-based photocatalyst, the antibacterial and bacteriostatic activity of the guanidino functional group is effectively utilized, the ecological risk caused by the metal-based photocatalyst is avoided, the high active oxygen free radicals ROS generated by the photocatalyst are utilized to persistently interfere with the material metabolism of microorganisms, and the reproduction of pathogenic bacteria is limited and apoptosis occurs without inhibiting the growth of beneficial bacteria. The disinfectant nanoparticles with photocatalytic function are in the form of a spray, are convenient to apply, can be directly disinfected by using indoor visible light resources, show a significant inhibitory effect on pathogenic bacteria carried by aerosol particulate matters in emergency rooms and in all seasons, and can be sprayed on the surface of medical equipment to help reduce the reproduction of pathogenic bacteria and the spread of viruses.

The invention discloses a guanidine nitrate gas production drug for an airbag and a preparation method thereof, the guanidine nitrate gas production drug comprises the following components by mass percentage: 45%-49% of guanidine nitrate, 19%-21% of potassium perchlorate, 24%-26% of strontium nitrate, 3%-5% of copper oxide, 3%-5% of polyvinyl alcohol, and 0.3%-0.5% of free-flowing auxiliary materials, and the sum of the mass percentage of the components is 100%. The obtained gas production medicine is large in gas production rate, stable in combustion performance, small in residue amount and low in sensitivity, and a direction is provided for developing miniaturized safety airbags and improving essential safety of medicine manufacturing; the preparation method effectively ensures the product quality and stability in the production process.