125 results about "Zinc Supplements" patented technology

Methods and compositions are provided for increasing responsiveness to therapeutic metalloproteases including increasing and/or maximizing responsiveness and preventing botulinum and tetanus toxin resistance due to a functional deficiency of zinc. Also provided are methods for zinc replacement or supplement in lacking individuals comprising the administration of a zinc supplement for a loading period and/or administration of a phytase supplement together with the zinc supplement. Also provided are methods for standardization of botulinum toxin potency assays that provide for greater certainty and margins of safety in the use of products from different manufacturers.

The invention discloses an artificial culture method of a zinc-rich cordyceps militaris fruit body and a culture medium thereof. The culture medium comprises the following components by weight portions: 40-65 portions of rice, 0.5-2.0 portions of a yeast extract, 60-85 portions of water and 0.01-1.0 portion of zinc sulfate with the natural PH value. The artificial culture method comprises the following steps: preparation of the culture medium, canning and sterilization; cooling and inoculation; culture; collection of the fruit body; drying and granulation. The method has the advantages of simple operation, short culture period, high yield of the fruit body, no pollution, no waste and zinc supplement function, and the method is suitable for industrialized production.

The invention relates to a preparation method for polypeptide chelating zinc salt from the fish skin of tilapia, which is characterized in that the fish skin of tilapia is adopted as the material; the enzymatic method is adopted to prepare fish skin polypeptide (TSP-I); the water bath heating method is adopted to prepare the polypeptide chelating zinc salt from the fish skin of tilapia with the fish skin polypeptide liquid and zinc sulfate; and the chelating reaction conditions of the two are that: the content of polypeptide in the TSP-I solution is adopted as index; the mass ratio of polypeptide to zinc sulfate is 3 : 1; the chelating temperature is 60 DEG C; the pH value of reaction is 6.0; and the reaction time is 0.5 hr. The preparation method for polypeptide chelating zinc salt from the fish skin of tilapia has the advantages that the resource waste problem of tilapia leftover is solved; the high-efficiency preparation method of zinc supplement agent is provided; and the preparedpolypeptide chelating zinc salt from the fish skin is a popular and natural production with health function.

The invention discloses a preparation method for polyaspartic acid zinc as an agricultural zinc supplement. The method comprises the following steps of: a, adding a proper amount of acid into a solution of polyaspartic acid calcium, wherein the mass percentage of the solution is 20 to 40 percent, stirring the solution and adjusting the pH value of the solution to 4 to 5 to obtain the acidic polyaspartic acid calcium solution, wherein the molecular weight of the polyaspartic acid calcium is 1,500 to 50,000; and b, adding quantitative amount of zinc sulfate into the acidic polyaspartic acid calcium solution, stirring the solution for 2 to 4 hours at the heating temperature of 40 to 80 DEG C, and filtering the solution to obtain the solution of the polyaspartic acid zinc. The preparation method is simple and convenient to perform and low in cost; the effect is stable; the purity is high; and the solubility of the obtained polyaspartic acid zinc is good.

The invention provides a preparation method and application of soybean-source zinc chelating peptide and peptide-zinc chelate. Soybeans as a material are produced into soybean protein isolate by an extraction and separation process, the soybean protein isolate and protease carry out hydrolysis reaction, active peptide with small molecular weight is obtained by enzymolysis, the peptide reacts with zinc salt, and thereby the peptide-zinc chelate is prepared. By adopting the high-quality soybeans as the material, the high-quality soybean protein isolate is prepared by the invention through the extraction and separation process; the protein is put into an enzymatic vessel and added with an appropriate amount of water to prepare protein pulp, the pH value of the soybean protein pulp is regulated, the protease is then added for hydrolysis reaction, the reaction solution is put into boiled water and cooked for enzyme deactivation after hydrolysis is complete, and thereby hydrolysate is obtained; the hydrolysate is centrifuged, and after the supernate is dried, the crude powder of the zinc chelating peptide is obtained. The zinc chelating peptide prepared by the invention can be directly used as a natural antioxidant to delay aging. In addition, the zinc chelating peptide can also be used to prepare an excellent parent for the peptide-zinc chelate, and the peptide-zinc chelator can be chelated with different trace elements to prepare zinc supplements which are used for treating the nutrient element deficiency symptoms of the body.

The invention discloses a zinc supplement method for cultivating chrysanthemum. The zinc supplement method includes steps of performing cutting for the chrysanthemum, and controlling water in a vain growth period of the chrysanthemum from July to August so that the chrysanthemum withers; piecing stems at lower ends of leaves of growing points of the chrysanthemum by a disinfected needle; performing topping, in other words, shearing 1-2cm tops of branches by scissors after lengths of the branches of the chrysanthemum reach 10-15cm and the weather keeps sunny for 2-3 days continuously; and applying fertilizers to the chrysanthemum. The zinc supplement method for cultivating the chrysanthemum has the advantages that the chrysanthemum is subjected to cutting ahead of schedule, tops of the chrysanthemum are removed ahead of schedule, accordingly, development of root systems of the chrysanthemum is promoted, a foundation is laid for future strong seedlings of the chrysanthemum, the chrysanthemum is effectively dwarfed by means of controlling the water, piecing the stems, applying the organic fertilizers and the like, nutrients rich in zinc are mixed into soil by means of spraying zinc fertilizers, and an effect of supplementing the zinc into the chrysanthemum is realized.

The invention discloses a preparation method of a dictyophora indusiata polysaccharide-zinc chelate with antitumor activity. The method comprises the following steps of (1) extracting dictyophora indusiata polysaccharide; (2) separating the dictyophora indusiata polysaccharide; (3) purifying the dictyophora indusiata polysaccharide; (4) adding an inorganic zinc source in a dictyophora indusiata polysaccharide solution to carry out chelation reaction; (5) carrying out alcohol precipitation; and (6) carrying out freeze drying to obtain the dictyophora indusiata polysaccharide-zinc chelate. The dictyophora indusiata polysaccharide-zinc chelate researched by the invention is effectively applied to preparation of zinc supplementing health products and medicines; and proven by an MTT method, a flow cytometry method, a Hoechst33258 staining method and a DNALadder and JC-1 staining method, the chelate has remarkable antitumor bioactivity so as to be expected to become an efficient and low-toxicity drug for treating cancers particularly liver cancer.

The invention relates to a zinc calcium gluconate oral solution. The zinc calcium gluconate oral solution is prepared from zinc calcium gluconate and cane sugar which serve as main raw materials and auxiliary materials in a certain ratio. According to the zinc calcium gluconate oral solution, ingredients and a process meet the specifications of Food Hygiene Law of the People's Republic of China and Provisions for Health Food Registration, so the zinc calcium gluconate oral solution has a good mouthfeel, is uniform and stable and can be absorbed by human bodies easily, and is suitable for the calcium supplement and zinc supplement of people.

An zinc supplement used for the forage of animals and fowls and human health-care food or medicine is a porous mineral material carried superfine Zn powder. It is prepared through providing mineral material as micro reactor and reducing the Zn salt to obtain superfine Zn powder.

The invention discloses a preparation method of a polysaccharide-zinc complex and a zinc supplement, and relates to the technical field of preparation of zinc supplements. The preparation method of the polysaccharide-zinc complex comprises the following steps: adding zinc acetate into a polysaccharide solution and adjusting pH to 6-7 to obtain a mixed solution; performing a reaction on the mixed solution for 2-3 hours under a temperature of 60-70 DEG C under a water-bath condition to obtain a reaction solution; and dialyzing the cooled reaction solution with flowing water, and separating and purifying a retentate to obtain the polysaccharide-zinc complex. A chelation reaction condition (temperature, pH, reaction time and the like) of polysaccharide molecules and zinc is optimized, so thatthe yield and the loading capacity of the zinc in the polysaccharide-zinc complex are greatly increased; in addition, the zinc supplement provided by the invention uses a codonopsis polysaccharide-zinc complex and a carboxymethyl pachyman-zinc complex as main effective components, so that the defects of low absorption efficiency and availability of the existing inorganic metal salt zinc supplementare overcome.

Treatments are disclosed for inflammatory, autoimmune, or other disorders characterized by excessive activity of calprotectin, a protein that normally defends against microbial infections by sequestering available zinc, at a site of infection. Excessive calprotectin activity, which can cause zinc deficiencies in localized tissues, can create or aggravate various disorders. However, ingestion of systemic (oral) zinc supplements tends to activate offsetting mechanisms, and such supplements therefore usually are ineffective. Accordingly, targeted treatments are disclosed herein for suppressing and controlling excessive calprotectin activity, in local tissues. Such methods include targeted injections of zinc solutions, and plasmapheresis treatment. Screening tests also are described for identifying non-protein drugs that can either (i) bind specifically to the zinc-binding sites of calprotectin, or (ii) suppress the release of calprotectin by neutrophil cells.

The invention mainly relates to the field of food processing, and discloses zinc supplementing edible salt. The zinc supplementing edible salt is prepared from the following raw materials in parts by weight: iodine-free table salt, peanuts, eggs, Angel saccharomyces cerevisiae, acetic acid bacteria, complex enzymes, papain, zinc sulfate and a purslane herb extract. The zinc supplementing edible salt provided by the invention is balanced in nutrients and rich in amino acids, vitamins and organic zinc, and can protect heart and cerebral vessels, promote growth and development, enhance immunity and delay senescence; the used main raw material is the iodine-free table salt, so that the iodine content in finished products is reduced, and the production of high-iodine symptoms is avoided; and the zinc supplementing edible salt is convenient to eat, the sale volume of the zinc supplementing edible salt is increased by 11.6%, the economic benefits are increased by 10.2%, and the zinc absorptivity of the zinc supplementing edible salt disclosed by the invention is increased by 35.6% compared with that of zinc supplementing edible salt sold in the market.

The invention discloses a preparation method and application of a marine polypeptide-zinc chelate. Firstly, the protein in marine animals and plants and their leftovers is extracted by alkali-dissolving acid precipitation method, or the marine animals and plants and their leftovers are crushed, After refining, add protease to the obtained protein or slurry for enzymolysis, inactivate the enzyme, and prepare a marine polypeptide complex solution; then use inorganic zinc acetate solution or zinc sulfate solution to chelate with marine polypeptide to obtain marine polypeptide-zinc chelation The obtained marine polypeptide-zinc chelate can be further prepared into snack food, nutraceutical or medicine. The preparation process of the present invention is simple; the prepared marine polypeptide-zinc chelate and its products have a unique chelation system and transport mechanism, are safe, non-toxic, easy to be absorbed, and can supplement amino acids and zinc at the same time, and will surely become a zinc supplement It provides a new idea for the application of marine animals and plants and their leftovers.

The invention relates to the field of food and food processing, in particular to a zinc-supplementing children steak and a preparation method thereof. The zinc-supplementing children steak is prepared from raw materials namely sirloin, salt, white granulated sugar, phosphate, protein isolate, starch, edible zinc powder, spice, black pepper powder, monosodium glutamate, essence, glutamine transaminase and ice water by means of processes of unfreezing, cutting, material liquid preparation, injection, double rolling and rubbing, filling, standing, quick freezing and the like. Trace elements zinc can be uniformly added into children steak by means of the process, and the total zinc intake quantity of children is accurately calculated and controlled according to the steak intake quantity of the children, and the aim of reasonably supplementing zinc is finally achieved.

The invention relates to a preparation method of edible and medicinal fungi protein peptide-zinc chelate. The preparation method comprises the following steps: extracting proteins from edible and medicinal fungus by an alkali-soluble acid precipitation method or an ammonium sulfate precipitation method; performing restricted enzymatic hydrolysis on the edible and medicinal fungi proteins by alkaline proteases, neutral proteases or compound proteases, so that an enzymatic hydrolysate of the edible and medicinal fungi proteins is prepared; and chelating zinc in inorganic zinc acetate or zinc sulfate with the edible and medicinal fungi protein peptide, so that the edible and medicinal fungi protein peptide-zinc chelate is prepared. The alkali-soluble acid precipitation method or the ammonium sulfate precipitation method utilized in the method is capable of obviously improving extraction rates of the edible fungi proteins; and the time of the enzymatic hydrolysis is controlled so as to effectively control degradation degrees of the proteins. A preparation technology of the polypeptide-zinc chelate is simple. The zinc-peptide chelate prepared by the preparation metahod is unique in chelate system and transport mechanism, and is easy to absorb, safe, non-toxic and low in cost; the zinc-peptide chelate is capable of supplementing amino acids and zinc at the same time, so that the zinc-peptide chelate will become the first choice among zinc supplements. The preparation method of edible and medicinal fungi protein peptide-zinc chelate provides a new idea to edible fungi applications.

The invention relates to a starter for and a preparation method of yogurt enriched with zinc, belonging to the field of dairy and processing thereof. The method is specifically characterized by mixing and inoculating lactobacillus into the ZnSO4-containing MRS or TJA culture medium and enriching lactobacillus with zinc, then centrifugally collecting thalli at 2-6 DEG C and preparing the thalli into the starter for yogurt enriched with zinc and fermenting the fresh milk or reconstituted milk to produce the functional yogurt enriched with organic zinc. The main technical indexes of the yogurt prepared by the method conform to the relevant specifications in the national standard GB 2746-1999, and in the yogurt, the content of non-fat milk solids and the acidity is a bit high (the content of non-fat milk solids is not less than 8.2% and the acidity is not less than 72 degrees T) and the content of organic zinc is 6.1-11.2mg/kg. The yogurt prepared by the method can balance the intestinal flora, improve the immune, lower the cholesterol and promote the appetite, and the organic zinc in the yogurt is easy to absorb and utilize by human bodies, can reduce the side effect of inorganic zinc supplement on human bodies and is a good dairy product with the function of supplementing zinc.

The invention mainly relates to the technical field of fruit wine fermentation, and discloses a preparation method of zinc supplementing strawberry wine. The preparation method includes cleaning, pulping, enzymolysis, primary fermentation, secondary fermentation and filtering. Operation is facilitated, the zinc content of the strawberry wine is 4.17mg/100ml, the strawberry wine is heavy in aromatic flavor, sour, sweet, palatable and clear, the healthcare effect of the strawberry wine is improved, strawberry wine types on the market are increased, and nutrition and healthcare requirements of consumers are met. Fresh strawberries are washed and then soaked in salt solution and vitamin C solution, residual pesticides and stains in the strawberries can be leached, oxidization is avoided, and bright colors of the strawberries are kept. Chitosan solution is added in pulping, growth of sundry fungi can be inhibited, deposition of unstable substances in the fermentation process can be promoted, the wine is kept clear and stable, long-time clarifying treatment process after traditional fermentation is avoided, and fermentation efficiency is improved.

The invention discloses zinc-supplementing health porridge. The zinc-supplementing health porridge is prepared from the following raw materials: rice, unpolished rice, oat, highland barley, green soybeans, broom corn millet rice, peanuts, shiitake mushrooms, nostoc flagelliforme, watermelon seeds, chicken hearts, shrimps, traditional Chinese medicines, table salt, soybean oligosaccharides, lactic acid bacteria, zinc-enriching yeast and spirulina polysaccharides. The zinc-supplementing health porridge disclosed by the invention has moderate sweetness and comprehensive nutrients, contains rich organic zinc and is easy to digest; the zinc-supplementing health porridge has the effects of enhancing the immunity, protecting cordial vessels, promoting metabolism, promoting intestinal functions, resisting oxidization and resisting cancers; fruit and vegetable pulp and meat mash are fermented to generate micro-molecular probiotic substances; a fermentation aroma is rich and a meat smell is removed; the product has a moderate sour degree, is sour, sweet and palatable, has balanced nutrients and can promote the absorption of organisms; a plurality of types of traditional Chinese medicine extract and nutritional agents are added, and all the raw materials have a coordinating effect, so that the absorption and the utilization of the zinc element are promoted, and the zinc-supplementing health porridge is nutritional and healthy; and the zinc-supplementing health porridge is convenient to carry and eat and can be eaten while a package is opened, so that a fast-paced life manner is met, and the product is convenient to carry and eat when people go out to travel or have a business trip.

The invention relates to a method for preparing zinc supplementing agent carboxymethyl chitosan oligosaccharide zinc, which is characterized in that 10g of carboxymethyl chitosan is taken and put into a three-neck flask, and is added with 90ml of 2% H2O2 in batches when being stirred for full reaction until the carboxymethyl chitosan is completely dissolved; pH value is adjusted to be 7, the precipitation is filtered out, the product is washed, and filtrate and washing liquid are collected; the filtrate and the washing liquid are decompressed and concentrated, and then precipitated, filtered and washed by ethanol; finally, the product is processed by vacuum drying with the drying temperature controlled to be 60 DEG C. The invention has the advantages that the carboxymethyl chitosan is prepared after chitosan oligosaccharide is modified, so as to have the pharmacological actions of arrhythmia resistance, anticoagulation, infection resistance and the like; the carboxymethyl chitosan oligosaccharide zinc is natural modified product and has better safety and biological activity compared with other zinc supplementing agents.

The invention relates to a preparation method of a protein peptide and zinc chelate suitable for ruminants. The preparation method mainly comprises the following steps: preparing a protein solution, carrying out enzymolysis, carrying out ultrafiltration, carrying out chelating, and carrying out spray drying, thus obtaining the protein peptide and zinc chelate. According to the method, soybean protein which is wide in source serves as a protein peptide source, inorganic zinc salt serves as a zinc source, the zinc element and the protein peptide are chelated, the technological process is simple,the cost is low, and the method is suitable for large-scale industrial production. The product prepared by the invention is high in small molecular peptide content and high in chelated zinc ion content, and is a novel high-efficiency zinc supplement agent for feed.

The invention mainly relates to the technical field of tea processing, and discloses a preparation method of zinc-rich white tea. The method comprises the following steps: picking tea leaves; carrying out first drying; carrying out zinc supplement; carrying out fermentation; carrying out withering; carrying out second drying; and carrying out packaging. The method is simple, and the white tea can be prepared in batches. The white tea has heavy aroma, and is fat, exquisite, full of down, and fresh and sweet in taste. The zinc content of the white tea is 1.64mg per 100g. The method maintains the yellowish green luster of the tea leaves, and can improve the health-care functions of the white tea. The white tea is edible for any population so as to extend marketing scope. Room temperature storage is used for the white tea so as to greatly save transportation costs and storage costs, and improve economic income by 13.7%. The white tea is organic tea picked at high attitude, has fresh and heavy aroma. The white tea is green, pollution-free, and safe and healthful for the human body. The tea leaves are picked, and then are dried in a dryer at moderate temperature, so that excessive nutrient consumption of the tea leaves caused by respiration is avoided, and the aroma and luster of the tea leaves are maintained.

The invention relates to the technical field of mycelium zinc polysaccharides, in particular to a Thelephoraganbajun Zang strain TG-1. The collection number of the Thelephoraganbajun Zang strain TG-1 is CGMCC No.12977. A preparation method of a Thelephoraganbajun Zang mycelium zinc polysaccharide comprises the following steps: fermenting the Thelephoraganbajun Zang strain TG-1 in a liquid culture medium added with a zinc salt; separating mycelia; extracting the Thelephoraganbajun Zang mycelium zinc polysaccharide. The invention further discloses an application of the Thelephoraganbajun Zang mycelium zinc polysaccharide to preparation of a zinc supplement anti-aging health-care product. The Thelephoraganbajun Zang strain TG-1 has very high zinc element absorption and transformation capabilities, a high zinc element endurance capability and a strong mycelium growth capability, and can well enrich zinc elements during liquid fermentation. Thus, The Thelephoraganbajun Zang strain TG-1 has very important significance to the production of the Thelephoraganbajun Zang mycelium zinc polysaccharide and increase in the content of zinc in the zinc polysaccharide.