23 results about "Zinc Supplements" patented technology

The present invention provides a selenium- and zinc-enriched yeast and its application, which relates to the field of microbial fermentation. The selenium- and zinc-enriched yeast provided by the present invention is obtained by culturing Saccharomyces cerevisiae mei2101.1 in a selenium- and zinc-enriched medium. Saccharomyces cerevisiae mei2101.1 can not only convert inorganic selenium and zinc into organic selenium and zinc simultaneously (the selenium enrichment amount is 1.99 mg / g, and the zinc enrichment amount is 48.80 mg / g), but also has high temperature resistance (resistant to high temperatures of 50-60 °C) and acid-base resistance (resistant to acidity with a pH of 4.5-5.6 and alkalinity with a pH of 11-12). When the selenium- and zinc-enriched yeast is added as a fermentation agent, selenium supplement, and zinc supplement to animal feeds that need to be granulated (such as piglet, fish, or layer chick feeds, etc.), it can resist the damage of high temperature during granulation to the yeast activity, greatly reduce the toxicity of inorganic selenium and zinc additives, and gradually replace zinc oxide and sodium selenite as an antibiotic-free livestock and poultry feed additive, having broad application prospects.

The present invention relates to a milk protein peptide with zinc chelating activity and its application in the preparation of zinc supplements. The sequence of the milk protein peptide is: EMPFPK (Glu-Met-Pro-Phe-Pro-Lys) and / or EAMAPKHKEMPFPK (Glu-Ala-Met-Ala-Pro-Lys-His-Lys-Glu-Met-Pro-Phe-Pro-Lys). The milk protein peptide not only has a strong zinc chelating ability (chelating rate reaches more than 64%), but also can increase the transport amount of zinc by human intestinal adenocarcinoma cell Caco-2 cell monolayer, and has a strong intestinal zinc absorption promoting activity. In addition, the milk protein peptide of the present invention is derived from milk, is non-toxic, and has high safety.

The invention discloses a lycium barbarum polysaccharide-zinc compound, a preparation method thereof and application of the lycium barbarum polysaccharide-zinc compound in a zinc supplementing preparation. The invention belongs to the technical field of high-molecular polysaccharide chelation. The invention solves the problems of high preparation cost, low yield and low zinc content of the zinc supplement preparation in the prior art. The lycium barbarum polysaccharide is subjected to incomplete hydrolysis to obtain the low-molecular-weight lycium barbarum polysaccharide with the weight-average molecular weight of about 3680Da, the zinc ion chelation rate of the lycium barbarum polysaccharide-zinc compound prepared with the small molecular weight can reach 95-98%, the zinc content can reach 28-35%, and the zinc ion chelation rate and the zinc content are far higher than those in the prior art. The lycium barbarum polysaccharide-zinc compound prepared by the invention has the advantages of high bioavailability, low toxicity, easiness in digestion and absorption and the like, shows excellent biological activity in the aspects of oxidation resistance, blood sugar reduction, inflammation resistance, bacteria resistance, liver protection and the like, and can also be used as a high-quality zinc supplementing agent.

The invention provides a preparation method of zinc-loaded attapulgite with high bioavailability, and belongs to the technical field of functional composite materials. The attapulgite is modified through activation, ultrasonic dispersion and acidizing treatment, the specific surface area of the attapulgite is increased, the cation exchange capacity is increased, the problem that zinc ions are loaded in the attapulgite less is further solved by optimizing the zinc loading condition, and finally, accurate putting of the zinc ions is achieved through coating operation, so that the content of the zinc ions in the attapulgite is increased. The bioavailability of zinc ions is improved, the discharge of unabsorbed zinc ions is remarkably reduced, the burden on the ecological environment is reduced, and the requirement of sustainable development is met. Compared with zinc oxide, the zinc-loaded attapulgite with high bioavailability prepared by the method can realize similar or better growth and health performance under the condition of using lower zinc dosage, provides an economical and efficient zinc supplement strategy, has obvious advantages when the zinc dosage needs to be optimized, and achieves the purposes of reducing the use amount and replacing zinc oxide.

The invention discloses a preparation method of a novel zinc supplementing preparation with hydrogel as a carrier, and belongs to the field of food. The preparation method comprises the following steps: by taking commercially available fish skin gelatin as a raw material and adding sodium alginate as an auxiliary agent, firstly forming pH response type hydrogel through a self-assembly effect between the gelatin and the sodium alginate, then soaking the hydrogel in a zinc sulfate solution in combination with a Hough-Merster effect, and strengthening a gel structure by utilizing an effect of sulfate radicals, so as to prepare the hydrogel. Zinc ions are loaded in the hydrogel through permeation, so that a novel zinc supplementing preparation taking the hydrogel as a carrier is prepared. The hydrogel prepared by the method has certain pH responsiveness, the gel structure cannot be disintegrated in a stomach environment, zinc ions wrapped in the hydrogel can be protected from being interfered by the stomach environment and can be released in an intestinal environment, and the technical bottleneck problem of zinc supplement product development is solved.

The preparation method of the zinc-chelated salmon fishbone phosphopeptide comprises the following steps: adding water into salmon fishbone powder, homogenizing, centrifuging and drying to obtain salmon fishbone crude protein, hydrolyzing by using a compound enzyme, and filtering to obtain the zinc-chelated salmon fishbone phosphopeptide. Performing enzyme deactivation and centrifugation to obtain a salmon fish bone peptide solution, and performing dialysis and freeze drying to obtain salmon fish bone peptide freeze-dried powder; the preparation method comprises the following steps: compounding salmon fishbone peptide freeze-dried powder and sodium tripolyphosphate to prepare salmon fishbone phosphopeptide freeze-dried powder, dissolving the salmon fishbone phosphopeptide freeze-dried powder in water, carrying out chelation reaction on the salmon fishbone phosphopeptide freeze-dried powder and a zinc source to obtain a compound solution, and carrying out ethanol precipitation, centrifugal separation and drying treatment to obtain the zinc-chelated salmon fishbone phosphopeptide. The zinc-chelated salmon fishbone phosphopeptide prepared by the chelating reaction of the salmon fishbone compound enzyme phosphopeptide and zinc ions is high in antioxidant activity and strong in zinc binding capacity, the absorptivity and bioavailability of the zinc element are effectively improved, and the taste of the product is optimized.

The invention relates to a cow milk beta-casein derived intestinal zinc absorption promoting peptide and application thereof in preparation of a zinc supplement. The sequence of the peptide for promoting intestinal zinc absorption is YPVEPF, and the peptide is non-toxic, high in safety, capable of being specifically combined with Zn < 2 + >, high in zinc chelating capacity and capable of remarkably improving the zinc transport amount in a Caco-2 small intestine epithelial cell model, so that the peptide has the good activity of improving intestinal zinc absorption. The peptide capable of promoting intestinal zinc absorption can be obtained through a solid-phase synthesis method, so that large-scale production can be carried out, and the synthesized peptide capable of promoting intestinal zinc absorption is high in purity and stable in quality, and can meet current market requirements.

The invention discloses a steel member alloy co-permeation anti-corrosion process, and particularly relates to the technical field of zinc impregnation treatment, and the steel member alloy co-permeation anti-corrosion process comprises the following process steps: step 1, spraying a lanthanum hydroxide-containing ethanol activating solution on the surface of a polished steel member, drying and then charging; step 2, adding an impregnation agent into the zinc impregnation furnace layer by layer, wherein the bottom layer is an aluminum oxide anti-sticking agent, the middle layer is a mixture of zinc powder, aluminum powder, ammonium chloride and nano silicon dioxide, and the covering layer is a mixture of zinc powder and lanthanum hydroxide; and step 3, gradient temperature rise. According to the technology, under the condition of being compatible with an existing production line of a traditional technology, through the four innovative steps of rare earth pre-activation, gradient heating, dynamic zinc supplementing and inert gas cooling, the corrosion-resistant service life of a zinc impregnation layer is doubled, the workpiece deformation rate approaches zero, the cooling efficiency is improved, meanwhile, the cost of an anti-sticking agent and the loss of zinc powder are reduced, the comprehensive production cost is reduced, and the production efficiency is improved. And the industrial-grade precise zinc impregnation standard of zero rework, zero adhesion and zero performance fluctuation is achieved.

The invention discloses a zinc supplementing device for a zinc pot, and relates to the field of zinc plating processes, the zinc supplementing device comprises a zinc supplementing hanging frame, a supporting movable mechanism is arranged in the zinc supplementing hanging frame, the supporting movable mechanism comprises a plurality of movable rods arranged in the zinc supplementing hanging frame, the movable rods are alternately distributed up and down, and connecting rods are fixed to the two ends of each movable rod; floating assemblies are arranged between the multiple movable rods and the zinc supplementing hanging frame, a movable assembly is arranged between the two supporting beams, and turbulent flow mechanisms are arranged between the adjacent connecting rods. The movable assembly is used for driving the floating assembly, the floating assembly drives the multiple connecting rods to move, the multiple movable rods move in a staggered mode when supporting a zinc block, meanwhile, the turbulent flow mechanism generates forced convection in zinc liquid, and therefore the heat transfer process is remarkably accelerated, the time needed for zinc supplementing is shortened, and the production efficiency is improved; meanwhile, a low-temperature zinc liquid boundary layer on the surface of the zinc block can be taken away through fluid disturbance, and high-temperature zinc liquid is introduced.

The invention discloses a zinc supplementing machine which comprises a rack, a feeding and discharging guide mechanism is mounted on the inner wall of the rack, during use, a zinc supplementing brush roller is fixed to a mounting frame, a base is fixed to the set position of a cold bending machine, a preservative liquid barrel is fixed to the top of the mounting frame, a liquid conveying pipe at the lower end of the preservative liquid barrel is connected to the zinc supplementing brush roller, and preservative liquid is conveyed; according to the use requirement, the flow rate switch between the preservative liquid barrel and the liquid conveying pipe is adjusted, the flow rate is controlled, the feeding guide roller and the discharging guide roller are installed on the inner wall of the installation frame, and the roller support is adjusted through the installation frame according to the use requirement; after being stressed, the spring can generate elasticity to enable the zinc supplementing brush roller to be attached to the cut surface of a product all the time, the brush roller absorbs preservative liquid to continuously supplement zinc to the cut surface of the product, finally redundant zinc supplementing liquid drops into a material collecting box below the brush roller device, the product exits through a discharging guide roller, and therefore the zinc supplementing machine is completed.

The invention relates to milk protein peptide with zinc chelating activity and application of the milk protein peptide in preparation of a zinc supplement. The sequence of the milk protein peptide is as follows: EMPFPK (Glu-Met-Pro-Phe-Pro-Lys) and / or EAMAPKHKEMPFPK (Glu-Ala-Met-Ala-Pro-Lys-His-Lys-Glu-Met-Pro-Phe-Pro-Ly s), and the sequence of the milk protein peptide is as follows: EMPFPK (Glu-Met-Pro-Phe-Pro-Lys) and / or EAMAPKHKEMPFPK (Glu-Ala-Met- The milk protein peptide not only has relatively strong zinc chelation capacity (the chelation rate reaches 64% or above), but also can improve the zinc transport amount of a cell monomolecular layer of human intestinal adenocarcinoma cells Caco-2, and has relatively strong intestinal zinc absorption promoting activity. In addition, the milk protein peptide disclosed by the invention is derived from milk, and is non-toxic and high in safety.

The present invention discloses a calcium gluconate zinc effervescent tablet with a high calcium content and a preparation method thereof, belonging to the technical field of pharmaceutical preparations. The calcium content of a unit preparation of the calcium gluconate zinc effervescent tablet is not less than 100 mg, and the unit preparation weight is not more than 4.5 g. The prescription of the calcium gluconate zinc effervescent tablet comprises the following ingredients: calcium gluconate, zinc gluconate, an absorption enhancer, an acid source, an alkali source, a filler, an adhesive, a wetting agent, a lubricant, a sweetener, a colorant, and a flavor. The absorption enhancer comprises casein phosphopeptide. The calcium gluconate zinc effervescent tablet is prepared by wet granulation, drying, mixing, and tableting. The calcium gluconate zinc effervescent tablet of the present invention has a high calcium content, good stability, a good taste, and good calcium and zinc absorption, and is a calcium and zinc supplement that can be used long-term and safely.

The invention relates to the field of zinc smelting, in particular to a process and device for replacing sponge lead with anode zinc. A device for replacing sponge lead with anode zinc comprises a replacement barrel, an upper cover is detachably connected to the replacement barrel, a liquid inlet pipe is connected to the upper cover, and a control valve is arranged on the liquid inlet pipe; the zinc supplementing assembly is arranged in the replacement barrel and connected with the upper cover; the liquid collecting ring is connected with the zinc supplementing assembly and communicates with the liquid inlet pipe; and the liquid discharge pipe is communicated with the replacement barrel, and the liquid discharge pipe is connected with a swirler. Through rotary friction of the conical cylinder and the friction cylinder, passivation layers generated on the surfaces of the zinc balls are continuously removed, continuous high activity of anode zinc is kept, the replacement efficiency is guaranteed, the stirring plate is matched with the bearing net, the surfaces of the zinc particles are further cleaned, movement of the zinc particles is promoted, complete reaction of the zinc particles is guaranteed, and generation of lead-containing zinc slag hazardous waste is avoided.

The invention relates to the technical field of bioactive peptide preparation and food processing, and particularly provides giant salamander peptide and zinc chelating peptide as well as a preparation method and application thereof. The technical problems that the deep processing level of existing giant salamanders is low, the bioavailability of traditional zinc supplements is low, and existing cranberry juice is single in nutrition function are solved. The giant salamander peptide is extracted from giant salamander muscles, and the zinc chelating peptide is prepared from the following raw materials in parts by mass: 1-5 parts of giant salamander peptide and 1 part of zinc sulfate heptahydrate. According to the invention, the giant salamander peptide and zinc sulfate heptahydrate are subjected to chelation reaction according to the proportion to prepare the zinc chelating peptide, and the zinc chelating peptide is applied to cranberry juice. According to the method, the deep processing way of the giant salamander raw materials is effectively expanded, the market category of giant salamander related high-added-value products is enriched, the nutritional quality of the cranberry beverage can be remarkably improved, the content of flavones and total phenols in the beverage is effectively increased, the requirements of consumers for healthy functional foods are met, and the method has wide application prospects and market value.

The present invention relates to a purple Talaromyces D2 and an application thereof, and belongs to the field of microbial technology. The purple Talaromyces D2 disclosed in the present invention has a deposit number of GDMCC NO.66320. The strain is obtained by isolating from soil and domesticating, and its zinc tolerance concentration can reach 2g / L, and the bacterium can efficiently convert inorganic zinc into organic active zinc that is easily absorbed and utilized by the human body. The organic zinc prepared by the bacterium has significant ABTS free radical scavenging ability, and at the same time has tyrosine kinase and 5-α reductase inhibitory ability; it shows that the organic zinc prepared by purple Talaromyces D2 can be used to prepare zinc supplement health products, and can also be used as a raw material for cosmetic active substances with both free radical scavenging and whitening effects, and has broad market application prospects.

The application discloses a casein peptide-zinc chelate TEDELQDKIHP-Zn for promoting zinc absorption, and an amino acid sequence of a polypeptide part of the casein peptide-zinc chelate is Thr-Glu-Asp-Glu-Leu-Gln-Asp-Lys-Ile-His-Pro; and a polypeptide and zinc chelate have a chelate ratio of 1:0.7. The casein peptide-zinc chelate TEDELQDKIHP-Zn has high gastrointestinal digestion stability, good absorption performance, and an effect of promoting zinc absorption is obviously better than that of traditional zinc supplements, such as zinc sulfate and zinc gluconate. The casein peptide-zinc chelate has very important significance for developing food, health products and medicines with a zinc supplement function.

The invention relates to the field of nutriment manufacturing, and discloses a preparation process of nano chelated calcium, magnesium and zinc. According to the preparation process, chelate and nanocrystalline technologies are combined, disodium ethylene diamine tetraacetate and soybean peptides are compounded, meanwhile, a precipitation-high-pressure homogenization process is combined, the chelation rate of the prepared nano chelated calcium, magnesium and zinc is as high as 97.3%, and the particle size D90 can reach 130 nm. Compared with the traditional calcium-magnesium-zinc supplements which are mostly inorganic mineral substances, have the general characteristics of water insolubility, poor in-vivo absorption and low bioavailability, the nano calcium-magnesium-zinc chelate prepared by the preparation method disclosed by the invention has the advantages that the bioavailability and solubility can be obviously improved.

The present application relates to a kind of bovine milk beta-casein source intestinal zinc absorption promoting peptide and its application in the preparation of zinc supplement.The sequence of the intestinal zinc absorption promoting peptide is YPVEPF, which is not only non-toxic, high safety, but also can be combined with Zn 2+ Specific binding, strong zinc chelating ability, can significantly improve the zinc transport amount in Caco-2 small intestinal epithelial cell model, thereby having good activity of improving intestinal zinc absorption.The intestinal zinc absorption promoting peptide can be obtained by solid phase synthesis method, so it can be produced on a large scale, and the synthesized intestinal zinc absorption promoting peptide not only has high purity but also stable peptide quality, which can meet the current market demand.

This invention provides an Antarctic krill-derived zinc chelating peptide, its preparation method, and its applications, belonging to the field of marine bioactive peptide technology. This invention utilizes defatted Antarctic krill powder to prepare high-affinity zinc chelating peptides, and the obtained peptides exhibit excellent zinc chelating capabilities. Mass spectrometry identification identified four peptides, all of which possess excellent zinc chelating abilities. The Antarctic krill-derived zinc chelating peptide prepared by this invention significantly enhances the zinc chelating ability compared to currently confirmed Antarctic krill peptides, and can be used as a carrier for fourth-generation zinc supplements in the prevention and treatment of zinc deficiency in common foods, health foods, and pharmaceuticals. This invention achieves high-value and precise utilization of defatted Antarctic krill powder, a processing byproduct, effectively improving resource utilization and industrial value, while also providing a new feasible approach for the development of safe and efficient zinc supplements.

The invention discloses xylooligosaccharide oral liquid beneficial to zinc absorption and a preparation method of the xylooligosaccharide oral liquid, and belongs to the technical field of food and health care products. The oral liquid is prepared by taking xylooligosaccharide, xylose and the zinc supplement as main components and supplementing with the buffering agent, the sweetening agent and the water, the prepared oral liquid can increase the absorption efficiency of the zinc supplement, and the zinc content in serum is increased to 29.2 mu moL / mL and is increased by 44.6% compared with that of single use of the zinc supplement; the intestinal barrier can be effectively improved, the intestinal absorption capacity is recovered, and the intestinal flora structure and abundance are improved.

The utility model discloses a zinc supplementing device for a galvanized welded pipe, which relates to the technical field of zinc supplementing devices and comprises a zinc supplementing machine, a gun holding mechanism, a polishing mechanism and an angle limiting mechanism, a zinc supplementing gun is mounted at one end of the zinc supplementing machine, the gun holding mechanism is mounted at one end of the zinc supplementing gun, and the gun holding mechanism comprises a gun clamping handle, a rotating hole, a retention ring and a bearing shaft. A gun clamping handle is installed at one end of the zinc supplementing gun, a rotating hole is formed in one end of the gun clamping handle, a retention ring is installed at one end of the rotating hole, and a bearing shaft is installed at one end of the gun clamping handle. Through the arrangement of the zinc supplementing machine, the zinc supplementing gun and the grinding mechanism, the zinc supplementing machine is started to conduct zinc supplementing work on the rotating galvanized welded pipe through the zinc supplementing gun, and the motor is started to drive the grinding column to rotate in the grinding bearing hole of the upper pressing plate; and through the acting force of the torsion spring, the upper pressing plate always presses and attaches the polishing column to the galvanized welded pipe on the pressing plate shaft, the surface of the galvanized uneven steel pipe is polished and leveled, and the polishing efficiency of the device is improved.

The invention discloses a corn polysaccharide zinc complex and a preparation method and application thereof, and belongs to the field of functional food and biomedicine technology. The preparation method specifically comprises the following steps: corn kernels are pretreated to obtain defatted corn flour, then water extraction and alcohol precipitation, drying and extracting corn polysaccharides, deproteinizing the corn polysaccharides by the Sevag method, and using the deproteinized corn polysaccharides and zinc chloride as raw materials to prepare corn polysaccharide zinc complexes. The invention can simultaneously have the physiological functions of corn polysaccharides and zinc, not only has a synergistic effect in regulating immunity, but also can effectively improve bioavailability, making it a zinc supplement with less side effects and capable of improving body immunity, suitable for people of all ages, simple production process, solves the problems of low absorption efficiency and single product of existing zinc supplements, and also has the advantages of low price and easy availability of raw materials compared with other polysaccharide zinc complexes.