The invention discloses a method for preparing a calcium-zinc stabilizer for shoe materials. The method comprises the following steps: S1. separately weighing 1-10 parts of zinc stearate, 10-25 partsof calcium stearate, 0.1-2 parts of zinc acetylacetone, 0.5-3 parts of calcium acetylacetonate, 20-50 parts of brucite, 5-15 parts of epoxidized soybean oil, 2-16 parts of lubricant, 5-20 parts of other metal soap, 5-25 parts of organic auxiliary heat stabilizer, 1-10 parts of unsaturated acid ester, 0.1-2 parts of antioxidant and 1-5 parts of dispersant; and S2. firstly, uniformly mixing variouspowder materials, then, adding a liquid ingredient, i.e., the epoxidized soybean oil, the lubricant and the dispersant, and continuing to carry out stirring until the material is of a wet powder or paste mixture, thereby obtaining the calcium-zinc stabilizer for the shoe materials. The calcium-zinc stabilizer for the shoe materials, prepared by the method, is free of organic lead salts and the like, thereby being environmentally friendly and safe; flying of dust can be effectively lowered; the whiteness and yellowing resistance of the shoe materials can be better guaranteed; the calcium-zinc stabilizer is difficult to separate out; and the color fastness and the like of the shoe materials can be improved.