The invention discloses acid-resistant pipeline steel and a pipe making method, and relates to the field of steel and iron materials. The acid-resistant pipeline steel comprises the chemical compositions of, by mass, 0.014%-0.024% of C, 0.10%-0.35% of Si, 0.60%-0.80% of Mn, less than or equal to 0.012% of P, less than or equal to 0.0010% of S, 0.030%-0.070% of Nb, 0.006%-0.020% of Ti, 0.10%-0.30%of Ni, 1.00%-1.10% of Cr, 0.15%-0.20% of Mo, 0.10%-0.30% of Cu, 0.010% of V, 0.015%-0.050% of Al, and the balance Fe and impurities. According to the acid-resistant pipeline steel and the pipe makingmethod, unique composition design is adopted, pipe making is carried out through edge milling, prebending, forming, welding, flaw detection, hole enlargement and hydraulic testing and other processesto meet the pipe making requirements of the acid-resistant pipeline steel.