156 results about "Borylation" patented technology

Designed functionality is incorporated onto a preformed aromatic polymer. The preformed aromatic polymer is provided in a reactive medium. Within that reactive medium is provided a borylation reagent and a catalyst for C—H borylation. A; and a C—H position on an aromatic ring on the preformed aromatic polymer is catalytically borylated with the borylating agent to form a borylated aromatic moiety on the preformed aromatic polymer as an incorporated boryl functionality. That boryl functionality may then be reacted with designed alternative functionalities.

The invention relates to an efficient, energy-saving and wear-resistant repairing agent with extreme pressure resistance (strong bearing capacity) and strong wear resistance, which greatly improves the performances of lubricating oil and lubricating grease, also greatly reduces energy consumption and mechanical wear and has a function of automatically repairing slight mechanical wear. The efficient, energy-saving and wear-resistant repairing agent with extreme pressure resistance and strong wear resistance comprises a coupling agent, a wear resistant agent, a lubricating agent, a reaction accelerant, a repairing factor and a dispersant and concretely comprises 0.5-2% of aluminium compound, 0.25-2% of calcium compound, 0.25-2% of magnesium compound, 0.25-2% of molybdenum compound, 1-6% of boronized amide, 0.5-5% of the coupling agent, 0.25-2% of the reaction accelerant, 50-95% of stabilizing agent and the dispersant. 3-5% of engine oil is added in the lubricating oil of an engine or gear. Detection results are as follows: the extreme pressure resistance is up to 108kg and is remarkably increased by three grades, the friction coefficient is reduced as comparison with the friction coefficient during no addition and is up to 55.6%, and the wear resistant effect is remarkable. During practical running tests of various vehicles, the oil saving efficiency is up to 11.0-20.90%.

The invention relates to a directional power-assisted oil composition and its application and mainly solves the problems of poor compatibility between a directional power-assisted oil and a rubber sealing member and the fault of a power steering system due to deformation or failure of the rubber sealing member with the application of a power-assisted oil composition in the power-assisted steering system in the prior art. The directional power-assisted oil composition comprises the following components of: by weight, a) 0.1-5 parts of boron polyisobutylene succinimide; b) 95-99.9 parts of base oil. By the adoption of the technical scheme, the problems are greatly solved. In addition, the technical scheme can be used in the industrial production of the directional power-assisted oil composition provided by the invention.

The invention discloses a high selectivity method for synthesizing moxifloxacin. The method comprises the following steps of: reacting boric anhydride with trifluoro acetic anhydride to obtain a chelant; reacting 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester with the chelant, cooling to room temperature, adding ice water, performing suction filtration, and washing a filter cake with water until neutrality to obtain a 1-ethyl-7-chloro-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid methyl ester trifluoroacetic anhydride boronized chelate; and reacting the 1-ethyl-7-chloro-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid methyl ester trifluoroacetic anhydride boronized chelate with (S,S)-2,8-diazabicyclo[4,3,0]nonane to obtain a 1-cyclopropyl-6-fluoro-7-([S,S]-2,8-diazabicyclo[4,3,0]nonane-8-methoxy-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid ethyl ester trifluoroacetic anhydride boronized chelate, recycling a solvent under reduced pressure, adding alkali, refluxing, discoloring, filtering, freezing, performing suction filtration, and drying a filter cake. The method is simple, mild in conditions, and high in selectivity, avoids difficultly separated impurities, is high in reaction yield and product purity, and is suitable for industrial production.

The invention relates to a new method for preparing crystalline transitional metal boride CoB (cobalt boride) with oxide or hydroxide of cobalt and borohydride of cobalt through solid phase reaction. The method provided by the invention comprises the steps as follows: uniformly mixing oxide or hydroxide of cobalt and borohydride of cobalt according to the molar ratio of 1:1 to 1:1.5, tabletting under the pressure of 15 to 20 MPa, keeping the temperature of 400 to 800 DEG C for 6 to 24 hours under the protection of argon gas, and cooling to the ambient temperature slowly; and the obtained product is washed fully with deionized water and alcohol and then vacuum dried, thus the product CoB can be obtained. The method has the characteristics that the synthetic method is novel, the adopted process is simple, and pure crystalline CoB can be obtained without high temperature, high pressure or other complicated procedures; and the used raw materials are simple and easy to obtain, and the cost is low, so that the method is applicable to mass production.

The present invention relates to a novel method for ruthenium-catalyzed selective boronation reaction of amides. According to the method, a hexacoordinated metal ruthenium complex containing a norbornadiene (NBD) ligand is taken as a catalyst, an N,N-disubstituted amide and bis(pinacolato)diboron are taken as reaction substrates, and in the absence of reaction solvents and under mild reaction conditions, a carbon-hydrogen bond of methylene at the ortho position of a nitrogen atom in the N,N-disubstituted amide is selectively subjected to a boronation reaction under efficient catalysis, so thata corresponding amide borate product is obtained. Compared with currently reported methods, the novel method generally has the advantages of wide substrate applicability, low catalyst usage amount, simple operation and the like. The method of the present invention realizes for the first time a selective C(sp3)-H boronation reaction of N,N-dimethyl substituted aromatic amide derivatives. In addition, the method realizes for the first time a metal-ruthenium-catalyzed selective dehydro-boronation reaction of N,N-disubstituted amides, and provides a completely new reaction strategy for organic synthetic intermediates of amide borates.

The invention provides a preparation method of a rutile type boron-doped titania (B-TiO2) microsphere with an exposed high energy crystal face {001} and belongs to the technical field of the preparation of inorganic material. The preparation method comprises the following specific steps: adding titanium boride (TiB) into a hydrochloric acid solution hydrazine containing natrium fluoride (NaF) to obtain a mixed solution, forcefully agitating, then transferring the mixed solution to a reactor with a polytetrafluoroethene lining, keeping the mixed solution at a constant temperature of 200 DEG C for 12-24 hours, naturally cooling the mixed solution to the room temperature so as to obtain a product, filtering the product, respectively washing and settling the product with distilled water and absolute ethyl alcohol for three times, drying the product at a temperature of 60-80 DEG C for 12-24 hours, and finally preparing the B-TiO2 microsphere with the exposed high energy crystal face {001}, of which exposing rate nearly reaches 100 percent. The preparation method is simple in preparation technology and good in repeatability; the prepared B-TiO2 microsphere is controllable and uniform in size and has a diameter of 3-5 micron; the element boron is doped, and is uniform in distribution and controllable in the amount of dopping; in addition, the prepared B-TiO2 microphere has excellent visible light catalytic activity, and is likely to be widely applied in the fields of photolytic water hydrogen preparation, organic contaminant degradation and the like.

The invention discloses polyaryletherketone containing a boric acid ester, azo polyaryletherketone and a preparation method thereof, and belongs to the technical field of preparation of a high polymer material. The method comprises the following steps: firstly, synthetizing bisphenol A polyaryletherketone, and carrying out catalytic boriding reaction under a 1,5-cyclooctadiene chloride iridium dipolymer by using the polyaryletherketone and boron pinacol ester; secondly, synthetizing a 4-iodine-4'-(N,N-dimethyl amine) azobenzene monomer; finally, reacting with the 4-iodine-4'-(N,N-dimethyl amine) azobenzene monomer under catalysis of tetrakispalladium by using a polyaryletherketone material containing the boric acid ester, so as to prepare the azo polyaryletherketone. By adopting the method, an azo monomer can be successfully led to the polyaryletherketone, but the performance of the polyaryletherketone is not affected, biphenyl structure azo polyaryletherketone with stable performance also can be generated, and the storage stability of the azo material can be improved. Therefore, the method is expected to be applied in the aspect of preparation of a novel azo polymer material.

The invention discloses a method for high-purity and high-yield preparation of p-chlorophenylboronic acid. The method comprises: (1) carrying out a Grignard reaction on magnesium chips and 1,4-dichlorobenzene under the action of an initiator to obtain a 4-chlorophenyl magnesium chloride Grignard reagent; and (2) carrying out a deep low temperature reaction on the 4-chlorophenyl magnesium chloride Grignard reagent obtained in the step (1) and trialkyl borate, carrying out acidolysis, and treating to obtain p-chlorophenylboronic acid. With the technical scheme of the present invention, the raw material cost and the production cost are substantially reduced, the reaction effect is good, the conversion rate during the boronization reaction is increased, the generation of the by-product impurities is reduced, the post-treatment is simple, the product purity is high, and the environmental pollution is reduced.

The invention discloses a synthesis method of cycloalkene-1-boronic acid pinacol ester. The synthesis method comprises three reaction steps of enabling cycloketone to react with phosphorus pentachloride to obtain 1-cycloolefin chloride, preparing cycloalkene-1-boronic acid through 1-cycloolefin chloride, lithium metal and a boronizing agent by the one-step method, and enabling cycloalkene-1-boronic acid to react with pinacol to obtain the final product. According to the method, the reaction is under mild conditions, 1-cycloolefin chloride can directly enter the next reaction without distilling and purifying, and intermediates and products obtained in each step do not need distilling, so that the operation is simple, and moreover, the raw materials are low in cost and easy to obtain, and as a result, mass production can be performed.

The invention discloses a silicon boron polymer and a preparation method therefor and an application thereof. The preparation method for the silicon boron polymer comprises two steps: firstly carrying out a reaction between 30-40 parts of a boron-containing compound and 20-30 parts of polyol to prepare a polyol ester; and then carrying out a reaction between 3-20 parts of the boronized polyol ester, 1-10 parts of methylsilicone oil, 60-100 parts of hydroxyl silicone oil, 0.1-15 parts of white carbon black and 0.01-0.5 part of a plasticizer unsaturated fatty acid to obtain the silicon boron polymer. Plasticine made from the synthetic silicon boron polymer has good bounce and stretchability; the elongation at break reaches 1000-2000%; the tensile strength is just 1-2 MPa; and the T type peel strength is just 0.1-1 kN/m. The preparation method disclosed by the invention is simple in process, short in preparation period and strong in operating controllablity; the stability of product performance can be improved; and the energy consumption is reduced, so that large-scale production is further facilitated. The prepared silicon boron polymer can be widely applied to the fields of toys for children, artistic molding, industrial molding and the like.

The invention discloses a carbon-based ferronickel bimetallic oxygen evolution catalyst and a preparation method thereof. The preparation method of the catalyst comprises the steps of: mixing carbon nanotubes and a boron-containing organic matter to obtain mixed powder, and calcining the mixed powder to obtain boronized carbon nanotubes; dispersing the boronized carbon nanotubes in water, adding anickel salt and an iron salt, performing full dipping to obtain a mixed material, conducting separation to obtain a solid substance, and performing drying to obtain precursor powder; and placing theprecursor powder in an inert atmosphere for heat treatment, and then conducting natural cooling to room temperature to obtain a target product. According to the preparation method, boron is used for modifying the surfaces of the carbon nanotubes, the reducing capacity of the surfaces of the carbon nanotubes is reduced, NiFeOOH clusters are successfully grown on the surface of the carbon nanotubes,the NiFeOOH cluster catalyst loaded by the carbon nanotubes is obtained, and the catalyst has the advantages of good conductivity, large specific surface area and the like, shows extremely high catalytic activity and has higher oxygen evolution activity. The production cost is low, and industrial application can be achieved.

The invention relates to a boron-induced amorphous layered double hydroxide electrocatalyst as well as preparation and application thereof. The preparation method comprises the following steps: firstly, synthesizing a transition metal layered double hydroxide nanosheet crystal precursor on a foamed nickel substrate by utilizing an in-situ growth method; and amorphizing the crystal precursor through a room-temperature boronizing method to finally prepare the self-supporting hydrogen evolution catalyst of the amorphous layered double hydroxide nanosheet. Compared with the prior art, the method for inducing the amorphization of the layered double hydroxide crystals by doping boron atoms enables the electrocatalyst to have more active sites, lower electron transfer impedance and better corrosion resistance. When the electrocatalyst is used in a hydrogen evolution reaction, the electrocatalyst can show excellent electrocatalytic activity and stability under the condition of great current density.

The invention belongs to the technical field of functional materials and discloses a soluble graphene nanoribbon as well as a synthetic method and an application thereof. The synthetic method comprises the steps that 2,6-dibromo-4-nitroaniline and alkyl/alkoxy arylboronic acid have a Suzuki coupling reaction, 2,6-bis(4-alkyl/alkoxy benzene)-4-nitroaniline is obtained and reduced, 2,6-bis(4-alkyl/alkoxy benzene)-1,4-phenylenediamine is obtained and has halogenation, 2,6-bis(4-alkyl/alkoxy benzene)-1,4-dibromo/iodobenzene is obtained and has an Miyaura borylation reaction, and 2,6-bis(4-alkyl/alkoxy benzene)-4-boronic acid pinacol ester-1-bromo/iodobenzene is obtained; then a poly-para-phenylene derivative is generated through the Suzuki coupling reaction, and a product is obtained through oxidative dehydrogenation. The soluble graphene nanoribbon can be applied to the fields of field effect transistors, photovoltaic cells, non-linear optics and sensing.

The invention belongs to the field of nano material preparation, and particularly relates to a novel method for preparing hafnium boride powder through a coprecipitation method. The specific process comprises the following steps: (1) dissolving HfCl4 in acetic acid to obtain a transparent solution A; dissolving boric acid and D-sorbitol in acetic acid, and stirring until the boric acid and the D-sorbitol are completely dissolved to obtain a transparent solution B; (2) after the solution B is cooled to room temperature, dropwise adding the solution A into the solution and stirring until white floccules are separated out and the solution becomes milk white; (3) drying an obtained sol; (4) fully grinding to obtain a white powdery hafnium boride precursor; and (5) calcining the hafnium boride precursor at a high temperature to obtain the nano hafnium boride powder. The preparation method is easy to operate, conditions are easy to control, and the production period is short; the prepared hafnium boride powder has nano-scale particle size and uniform distribution, and has good morphological characteristics, ultrahigh purity and high yield. And a technical basis is provided for realizing engineering and industrial preparation of high-performance, high-strength and ultrahigh-temperature ceramic materials.

The invention discloses a preparation method of hydroxyphenylboronic acid, which belongs to the technical field of boric acid synthesis in medical intermediates. The method comprises the following steps: starting from bromophenol, carrying out BOC, trimethylsilyl or benzyl protection, forming a Grignard reagent, reacting with borate, or carrying out one-pot reaction with borate and n-butyllithium,and hydrolyzing to obtain hydroxyphenylboronic acid. According to the invention, cheap and easily available protecting groups are adopted, so that the protecting groups are easy to remove during boronation reaction hydrolysis, industrial amplification is easy to realize, batch production is carried out on the scale of dozens of kilograms, and the process stability is good.

The invention belongs to the technical field of medicine synthesis, and in particular relates to a method for synthesizing a Crizotinib intermediate. The method comprises steps of: a) reacting a raw material 4-mesylate piperidine-1-formic acid tert-butyl ester (2) with 4-nitro pyrazole to prepare a compound 3; b) reducing nitro by using hydrazine hydrate to obtain an amino compound 4; and c) diazotizing the compound 4 by using tert-butyl nitrite, and reacting the compound 4 with a boric acid ester compound 5 in the presence of a free radical initiator benzoyl peroxide, so as to prepare the Crizotinib intermediate (1). Compared with an existing synthesis method, the method provided by the invention has the following advantages: a diazotization method is used to synthesize the boric acid ester product; and compared with an existing Miyaura boronation method catalyzed by Pd, the method avoids the usage of expensive palladium catalyst and ligand, and has the merits of mild reaction condition, high yield, simple operation, cheap and easily available raw materials and short reaction period, and is quite easy for industrialized mass production.

Provided are: a carbon material which has boron atoms and/or phosphorus atoms with their characteristic structures and functions intact introduced into a carbon material such as carbon nanotubes; anda method for manufacturing the carbon material. This carbon material has boron atoms and/or phosphorus atoms introduced to a proportion of the carbon atoms that constitute the carbon material, and ismanufactured by the method for manufacturing the carbon material, the method including: a step of bringing into contact a fluorination processing gas that includes a fluorine-containing gas with the carbon material to perform fluorination processing on the surface of the carbon material; and a step of bringing into contact a boronizing gas that includes a boron-containing gas with the carbon material after the fluorination processing to boronize the carbon material and/or bringing into contact a phosphorizing gas that includes a phosphorus-containing gas with the carbon material after the fluorination processing to phosphorize the carbon material.

Boronated polyphosphinohydrazide fire retardants are provided having the basic structural unit:

wherein,

Y is O or S;

R can be selected from H, alkyl (e.g., linear, branched, saturated, or unsaturated), aryl, heterocyclic, cycloaliphatic (e.g., saturated or unsaturated), or a metallocene (e.g., ferrocene, zirconocene or the like); and

n can be selected from 1 to 500.

The invention is directed to methods of converting a carboxylic acid group in a compound, via a redox active ester, to a corresponding boronic ester by treatment with bis(pinacolato)diboron-alkyllithium complex in the presence of a ligand, a Ni(ll) salt or a copper salt, and an Mg(ll) salt, in the presence of an alkyllithium or a lithium hydroxide or alkoxide salt. The product pinacolato boronateester can be cleaved to provide a boronic acid. The invention is also directed to methods of preparing various compounds of medical value comprising boronic acid groups, and to novel boronic-acid containing compounds of medicinal value, including an atorvastatin boronic acid analog, a vancomycin aglycone boronic acid analog, and boronic acid containing elastase inhibitors mCBK319, mCBK320, mCBK323, and RPX-7009.

The invention belongs to the field of ceramic material preparation, and discloses a method for preparing high-activity titanium boride ceramic powder through low-temperature microwave carbon thermal reduction. The process comprises the following steps: uniformly mixing boric acid, metatitanic acid, an organic carbon source and a reaction accelerator with deionized water, drying, and carrying out low-temperature carbon thermal reduction in a microwave atmosphere furnace to prepare the high-activity titanium boride ceramic powder. According to the invention, deionized water is used as a solvent, and a complex and lengthy sol-gel process is not needed; the raw materials directly react after being heated and decomposed, and the reaction activity is high; a reaction accelerator is introduced to improve the reaction rate and promote the reaction to be carried out at low temperature; and the high-activity TiB2 ceramic powder with fine crystal grains and uniform size is prepared by using microwaves at 1200-1550 DEG C within 5-50 minutes . Compared with an existing TiB2 powder preparation method with high energy consumption (1800-2100 DEG C) and high cost, the method has the advantages of being low in reaction temperature, short in reaction time, short in process, low in cost, environmentally friendly, capable of saving energy, reducing consumption and the like, simple and easy to control in process and suitable for industrial large-scale application.