The invention discloses a perfume concoction with an animal liver fragrance and a preparation method thereof. The perfume concoction comprises: by weight, 1 to 2% of ethyl maltol, 2 to 4% of 2-methyl butyraldehyde, 0.5 to 1% of furanone, 15 to 30% of 4-methyl-5-thiazoleethanol, 0.2 to 0.4% of 2-acetylpyrazine, 1 to 2% of butyric acid, 0.5 to 1% of 2,3,5-trimethylpyrazine, 0.5 to 1% of gamma-butyrolactone, 0.3 to 0.6% of 2,3,5,6-tetramethylpyrazine, 0.2 to 0.4% of 2-acetylthiophene, 0.02 to 0.05% of 2-methyl-3-mercaptofuran, 13 to 40% of glycerol triacetate, and 30 to 50% of liver extract. Theperfume concoction realizes that a substitute of a natural liver fragrance can be utilized as a feed additive to be used in pet feed. The preparation method of the perfume concoction is simple. Perfume materials composing the perfume concoction is safe and is easy for purchase. The fragrance of the perfume concoction is pleasant, stable and true to nature. The perfume concoction is preserved easily under the condition of package encapsulation.