The invention discloses a coffee grounds seedling raising matrix nutrition pot and a manufacturing method of the coffee grounds seedling raising matrix nutrition pot and belongs to the technical field of plant seedling raising devices. A pot body comprises, by weight, 3-6 percent of mature bacteria, 3-6 percent of functional bacteria, 0-5 percent of sugar, 0-3 percent of adhesive, 0-10 percent of water-retaining agent, and the balance of coffee grounds. In the time of preparation, the coffee grounds are smashed into 40-60 meshes, moisture content is adjusted to be 65-75 percent, and then alkaloid degrading bacteria are sequentially and evenly stirred with sugar and the coffee grounds and fermented for one to two days under the temperature of 20 DEG C to 30 DEG C. Phenol degrading bacteria are mixed into the obtained solution and fermented for two to three days under the temperature of 30 DEG C to 40 DEG C, grease degrading bacteria are stirred into the obtained solution for being fermented for two to three days under the temperature of 40 DEG C to 50 DEG C, and when the temperature is reduced to be 30 DEG C to 40 DEG C, functional bacteria are mixed into the obtained solution and fermented for one to two days. When materials are dried and the moisture content of the materials is within a range of 6-8 percent, the water-retaining agent and the adhesive are mixed into the obtained solution, and the solution is packed into a bag and formed in a compression mode. The pot body is high in content of organic matter and humus, good in air permeability and water permeability, high in seedling growing survival rate and capable of degrading naturally. The manufacturing method can achieve oriented,staged and sustainable decomposition of chemical constituents in the coffee grounds, the nutrient releasing cycle is long, the production cycle is short, and technology is simple.