Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

55results about How to "There is no problem of drug resistance" patented technology

Composite traditional Chinese medicinal sterilizing agent for dairy farm

The invention discloses a composite traditional Chinese medicinal sterilizing agent for a dairy farm which has no medicine residue and is environmentally friendly. The composite traditional Chinese medicinal sterilizing agent product is prepared by compounding traditional Chinese herbs such as gallnut, houttuynia cordata, coptis chinensis, scutellaria baicalensis, folium isatidis, herba andrographitis, radix isatidis, wild chrysanthemum flower, gingko, rhizoma acori graminei, magnolia officinalis, thyme, lysimachia christinae hance and the like in an ultrasonic auxiliary two-step extraction process. The composite traditional Chinese medicinal sterilizing agent has advantages the that the production process of ultrasonic auxiliary ethanol extraction of traditional Chinese herb and decoction is adopted in the preparation process of the composite traditional Chinese medicinal sterilizing agent, so that the aqueous soluble and alcohol soluble antibacterial active substances in the traditional Chinese herbs can be more adequately utilized; secondly, tween 80 and propanediol are added in the composite traditional Chinese medicinal sterilizing agent, so that the stability, adsorption property and viscosity of the sterilizing agent can be improved, and the effect of the composite traditional Chinese medicinal sterilizing agent can be further improved; thirdly, the product is environmentally friendly and safe, has no adverse effect on cow and has no problems such as medicine residue and drug resistance.
Owner:成都科宏达科技有限公司

Preparation method and application of Chinese herbal immunopotentiator for Salmo trutta marmoratus

The invention discloses a fermented Chinese herbal immunopotentiator for Salmo trutta marmoratus. The fermented Chinese herbal immunopotentiator has various effects such as prevention, healthcare, treatment, immunoregulation and the like so as to be a novel ideal green safe feed additive capable of substituting antibiotic drugs. The fermented Chinese herbal feed additive is prepared from a compound Chinese herbal medicine through a process comprising the steps: carrying out ultrasonic-assisted extraction on a Chinese herbal medicine, and carrying out two-step fermentation on multiple strains, so that the fermented Chinese herbal feed additive has double advantages of the Chinese herbal medicine and probiotics and can be used for efficiently regulating the intestinal health of the Salmo trutta marmoratus, treating both symptoms and root causes, consolidating the basis, keeping the intestinal microecology balanced and in the optimal immune state, increasing the digestibility of nutrient substances, improving the immunity of the organism of the Salmo trutta marmoratus, increasing the breeding income and reducing the breeding risk; and the fermented Chinese herbal immunopotentiator is used for replacing antibiotics and is free of adverse effects to the Salmo trutta marmoratus, safe in use and free of the problems such as drug residues, drug resistance and the like so as to have a wide market prospect.
Owner:QINGDAO JIARUI BIOLOGICAL TECH

Targeting antitumor drug using magnetic micro-nano material to destroy tumor blood vessels under driving of alternating magnetic field or radio frequency

The present invention discloses a novel use of a magnetic micro-nano material. The new use is application of the magnetic micro-nano material in manufacture of a targeting tumor treatment drug, the magnetic micro-nano material has all the following properties: (1) the magnetic micro-nano material is magnetic, sol that the magnetic micro-nano material can produce mechanical destructive effects on tumor blood vessel endothelial cells under driving of an alternating magnetic field or radio frequency; (2) the magnetic micro-nano material has a hydrophilic surface; (3) the magnetic micro-nano material has certain electronegativity on surface; and (4) the particle size range of the magnetic micro-nano material is 10-500nm, so that the magnetic micro-nano material has rigidity (namely, is not easy to deform). The magnetic micro-nano material can be specifically gathered and retained in tumor blood vessel parts by EPR effect after intravenous injection, and the mechanical destructive effects produced under driving of the alternating magnetic field or radio frequency can act on the tumor blood vessel endothelial cells highly selectively to further destroy tumor blood vessels to lead to tumor rapid necrosis and achieve the efficient tumor targeting treatment purpose.
Owner:赤峰福纳康生物技术有限公司 +1

Feed additive for weaned pigs, capable of controlling respiratory diseases and improving immunity

The invention discloses a feed additive for weaned pigs, capable of controlling respiratory diseases and improving immunity. The feed additive comprises the following raw materials by mass: a composite Chinese herbal medicine extract, amino acid chelate trace elements, vitamin C, folic acid, biotin, acidic pectinase, neutral protease, amylase, xylanase, phytase, cellulase, taurine, cysteamine, sodium butyrate and a microecological preparation, wherein composite Chinese herbal medicines comprise forsythia suspensa, honeysuckles, Chinese thorowax, acanthopanax bark, platycodon roots, field thistle herbs, nutgrass galingale rhizomes, folium isatidis, astragalus membranaceus, licorice roots, radix isatidis, mint, radix codonopsis, atractylodes rhizomes and glossy privet fruits. According to the feed additive disclosed by the invention, the composite Chinese herbal medicine extract, the amino acid chelate trace elements, the multizyme preparation, the microecological preparation and the like are in scientific compounding, so that the effect of synergistic reaction that various Chinese herbal medicines are compounded to have better effects than separate Chinese herbal medicine, is achieved, the products are notable in effects, and the respiratory disease of the weaned pigs can be effectively controlled. The feed additive is safe and convenient to use, the problems of drug residues, drug tolerance and the like are solved, and the feed additive has broad market prospects.
Owner:SHANDONG LVDUANTE VETERINARY DRUG IND

Chinese medicinal composition for promoting growing and fattening of meat chicken and preparation thereof

The invention relates to a Chinese medicinical composition for promoting broiler chicken to gain weight and the prepare method thereof, which comprises by weight parts of components: 30-60 parts by weight of cinnamon, 10-30 parts by weight of dried ginger, 5-15 parts by weight of liquorice, 5-15 parts by weight of fennel, 1-10 parts by weight of fried soybeans. The prepare method has the following steps:(1). weighing each component according to the proportioning by weight; (2). crushing every component mentioned above, through 40 mesh sieve, placing them in the groove type mixer together and stirring for 10-30 minutes; (3). through 100-300 mesh superfine comminution, the Chinese medicinical composition for promoting broiler chicken to gain weight is produced. The Chinese medicinical composition is pure Chinese medicinical preparation which is safe, environmental friendly without resistance problem. Every component in the prescription is coordinated and complemented for warming the middle-Jiao to remove cold, nourishing spleen and enriching qi, stimulating appetite, at the same time has functions of antibacterium, anti-inflammatory and improving body immunity. The product is used for promoting weight of broiler chicken, improving production and chicken flavor. The medicine material is convenient to access, has cheap price and good effect, can reduce production cost, and is suitable for large-scale production.
Owner:吴忠尚

Green immunopotentiator for pigs

The invention discloses a green immunopotentiator for pigs. The green immunopotentiator has various functions of prevention, healthcare, treatment, immunoregulation and the like. The green immunopotentiator for the pigs is an ideal, green, environment-friendly, safe and novel feed additive replacing an antibiotic drug. Compound Chinese herbal medicines such as houttuynia cordata, kudzu vine roots, gynostemma pentaphylla, isatis roots, glossy privet fruits, enteromorpha, liquorice, radix scutellariae, acanthopanax, folium isatidis, Chuanxiong rhizome, honeysuckle and stevia are subjected to 'Chinese herbal medicine ultrasonic wave-assisted extraction, multi-strain aerobic fermentation and anaerobic fermentation combined two-step fermentation' to obtain the fermented Chinese herbal medicine feed additive. The fermented Chinese herbal medicine feed additive has double advantages of the Chinese herbal medicines and probiotics, health of pig intestinal tracts can be efficiently conditioned, both principal and secondary aspects of diseases are treated, vital essence is reinforced, primordial qi is strengthened, intestinal micro-ecological balance and optimal immune state are kept, the digestion and absorption rate of nutrient substances is increased, pig body immunity is enhanced, raising income is increased, raising risk is reduced, and the feed additive replaces antibiotics, has no negative effect on the pigs, avoids the problems of drug residues, drug resistance and the like, and has a wide market prospect.
Owner:裕龙农牧科技股份有限公司

Fermented selenium-rich vegetable feed additive

The invention discloses a fermented selenium-rich vegetable feed additive. A preparation method of the fermented selenium-rich vegetable feed additive comprises the following three steps: (1) preparation of a selenium-rich yeast culture solution, (2) preparation of a traditional Chinese medicine fermentation culture medium and (3) traditional Chinese medicine fermentation. The preparation method is characterized in that the step (2) comprises the following steps: (2.1) preparation of a Chinese herbal medicine probiotics culture medium and (2.2) inoculation. The fermented selenium-rich vegetable feed additive designed by the invention is a novel environmentally-friendly safe feed additive which contains fermented traditional Chinese medicines and organic selenium and is capable of resisting heat stress of pigs. By adequately combining with physiological characteristics of heat stress pigs and taking oxidative stress resistance as the main characteristic, after pigs are fed with the additive, the weight increment and feed to gain ratio of the pigs in a high-temperature environment can be remarkably improved, the oxidation resistance and immunologic functions of the pigs can be enhanced, and the stress resistance of the pigs is effectively exerted; and after the additive is used for a long time, no toxic and side effects are generated, and no harmful substance is remained.
Owner:池州市兴牧饲料有限公司

Liver protecting Chinese medicine preparation for aquiculture animals and preparation method thereof

The invention relates to a liver protecting Chinese medicine preparation for aquiculture animals and a preparation method thereof. The liver protecting Chinese medicine preparation for the aquiculture animals is prepared from raw materials of turmeric concrete and corn starch according to certain mass ratio, and the method comprises the following steps: A. taking turmeric herb powder, and reflux-extracting with 500 mL 80 % v / v ethanol; B. filtering extracting solution, combining, and condensing through a rotary evaporator; C. transferring the turmeric extracting solution into a beaker at certain temperature, and adding the corn starch to mix uniformly; D. placing the turmeric extracting solution in a baking oven, and drying at certain temperature; E. taking dried medicine out, screening, and gaining the Chinese medicine preparation. The preparation protects livers of aquatic animals free from being damaged or from being relieved damage, avoids other concurrence diseases caused by the liver damage, and reduces the happening of aquatic animal disease. The medicine is plant-derived medicine, and is safe and effective; curcumin extracted through the method is high in total curcumin content, the recipe is reasonable, the effect is good, the method is feasible, the operation is convenient, and the requirement of intensive and large-scale cultivating of mixed feed in aquiculture is particularly facilitated.
Owner:武汉中博水产生物技术有限公司 +1

Multi-functional aquatic feed additive and preparation method thereof

The invention discloses a multi-functional aquatic feed additive. The multi-functional aquatic feed additive comprises the following raw materials in parts by weight: 5-15 parts of radix astragali, 10-20 parts of scutellaria lateriflora, 10-14 parts of radix codonopsis, 6-8 parts of caulis spatholobi, 3-7 parts of honeysuckle flowers, 3-5 parts of rheum officinale, 2-3 parts of taurine, 2-4 parts of biologically active peptides, 1-2 parts of probiotics, 3-5 parts of prebiotics, 0.1-1 part of malathion, 4-8 parts of rapeseed cakes, 20-30 parts of food processing wastes, and 2-3 parts of a biologically active bacterial agent. The multi-functional aquatic feed additive disclosed by the invention has advantages of both Chinese herbal medicines and the probiotics. The multi-functional aquatic feed additive is capable of efficiently conditioning intestinal health of aquatic animals, maintaining micro-ecological balance and optimal immune status of the intestinal track, increasing digestion and absorption rates to nutrients, enhancing immunity of animal bodies, improving aquaculture yields and reducing aquaculture risks; moreover, the multi-functional aquatic feed additive can be used instead of antibiotics, and is free of adverse effects on the aquatic animals, safe to use, and free of problems, such as drug residues, drug resistance and so on. In addition, a preparation method of the multi-functional aquatic feed additive provided by the invention is relatively low in material cost, easy in raw materials obtaining and simple in processes, and thus, the preparation method thereof has good application prospects.
Owner:安徽帝都农业生态园有限公司

Nano-enzyme bactericide based on bimetal organic framework as well as preparation method and application of nano-enzyme bactericide

The invention discloses a nano-enzyme bactericide based on a bimetallic organic framework as well as a preparation method and application of the nano-enzyme bactericide. The preparation method comprises the following steps of: (1) by taking a solution as a reaction medium, reacting cerium nitrate, copper nitrate and pyromellitic acid at room temperature to obtain a bimetal organic framework; and (2) calcining the bimetal organic framework in an air atmosphere at 200-400 DEG C for 1.5-3.5 hours to obtain the nano-enzyme bactericide based on the bimetal organic framework, which is used for inhibiting food-borne pathogenic bacteria. The nano-enzyme bactericide disclosed by the invention is a two-dimensional flaky quasi-MOFs material derived from the bimetal organic framework through low-temperature oxidation; the ano-enzyme bactericide has the biological enzyme-like catalytic activity, maintains the structural characteristics of the MOFs through the low-temperature oxidation, has improvedstability, enhances the electron transfer between metal sites, and greatly enhances the catalytic effect of nano-enzyme through the combination of the synergistic catalytic effect of double metals soas to achieve an efficient sterilization purpose.
Owner:SOUTH CHINA UNIV OF TECH

Hydrogel of lubricating coating, preparation method of hydrogel, hydrogel freeze-dried powder and application of hydrogel freeze-dried powder

The invention relates to the technical field of high polymer materials, and particularly discloses a hydrogel and a preparation method and application of freeze-dried powder of the hydrogel, and preparation raw materials of the hydrogel comprise acrylamide substances, chitosan substances and polyvinylpyrrolidone. The preparation method of the hydrogel comprises the following steps: preparing a chitosan substance into a solution A; preparing an acrylamide substance into a solution B with the mass concentration of 5-30%, adding an initiator and a cross-linking agent into the solution B, and mixing to obtain a solution C; mixing the solution A and the solution C, and adding polyvinylpyrrolidone with the mass concentration of 5-20% to obtain a solution D; and irradiating the solution D with ultraviolet light to obtain the hydrogel, and freeze-drying and grinding the hydrogel to obtain the hydrogel freeze-dried powder. The hydrogel has a double-network structure, is high in gel strength, is not easy to damage when being used for lubricating the interventional medical catheter, is small in friction coefficient, has good lubricity, and can be used for the medical interventional catheter or a medical interventional instrument.
Owner:INST OF MEDICINE & HEALTH GUANGDONG ACAD OF SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products