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107 results about "Crotonates" patented technology

Derivatives of BUTYRIC ACID that include a double bond between carbon 2 and 3 of the aliphatic structure. Included under this heading are a broad variety of acid forms, salts, esters, and amides that include the aminobutryrate structure.

Method for preparing butyrate clevidipine

The invention discloses a method for preparing butyrate clevidipine. The method comprises that 2, 3-dichlorobenzaldehyde, acetoacetate propionitrile ester and 3-amino-2-methyl crotonate are mixed and one-pot Hantzsch reaction is conducted, base catalyst is added to remove 2-cyanoethyl to obtain key intermediate, the key intermediate reacts with n-butyric acid chloromethyl ester to obtain butyrate clevidipine crude product, and the crude product is recrystallized to obtain high-purity butyrate clevidipine. Raw material 3-amino-2-methyl crotonate can be prepared by using low-price methyl acetoacetate. Raw material acetoacetate propionitrile ester can be prepared by using diketene. The synthesis of all raw materials requires no chromatographic separation for purification. The intermediate is synthesized through one-pot Hantzsch reaction, the reaction speed is fast, the condition is mild, the technological reliability is high and the purity of the intermediate is high. The conditions for the reaction of the key intermediate and the n-butyric acid chloromethyl ester can be easily controlled, the operation is simple and convenient, the cost is low, the post treatment requires no chromatographic separation for purification, the purity of the obtained butyrate clevidipine is above 99.5 percent and the mass production can be realized.
Owner:SUN YAT SEN UNIV +1

Ethyl 3-mercaptobutyrate as a perfuming agent and methods for preparing and using same

This invention pertains to a method for flavoring an ingestible composition with a flavoring agent in organoleptically purified form, unaccompanied by substances of natural origin present in mango. The flavoring agent may be used in a wide variety of ingestible vehicles such as chewing gum compositions, hard and soft confections, dairy products, beverage products including juice drinks and juice products, green vegetable and chicken products, and the like. The present invention also pertains to an ingestible composition comprising an ingestible vehicle and an organoleptically effective amount of the purified flavoring agent. The present invention further pertains to ethyl 3-mercaptobutyrate represented by the formula, CH3(SH)CHCH2COOCH2CH3, in purified form, unaccompanied by substances of natural origin present in mango. The present invention still further pertains to a method to confer, enhance, improve, or modify the odor properties of a perfuming composition or a perfumed article, which comprises adding to the perfuming composition or perfumed article, ethyl 3-mercaptobutyrate represented by the formula, CH3(SH)CHCH2COOCH2CH3. The present invention still further pertains to a perfuming composition or a perfumed article containing as an active perfuming ingredient, ethyl 3-mercaptobutyrate represented by the formula, CH3(SH)CHCH2COOCH2CH3. The present invention also pertains to a method for preparing ethyl 3-mercaptobutyrate which comprises reacting ethyl crotonate with sodium hydrogen sulfide and sodium bicarbonate to form the disulfide dimer of ethyl 3-mercaptobutyrate followed by reducing the disulfide dimer to yield ethyl 3-mercaptobutyrate.
Owner:BUSH BOAKE ALLEN LTD

Air purification material capable of releasing anions as well as preparation method and application of air purification material

The invention discloses an air purification material capable of releasing anions as well as a preparation method and application of the air purification material. The air purification material contains the following raw materials in parts by weight: 28-36 parts of akadama, 1-5 parts of ethyl crotonate, 11-19 parts of gypsum vitreum, 5-12 parts of butanediol and 3-7 parts of potassium tartrate. The preparation method comprises the following steps: crushing the akadama, mixing the akadama with an ethyl crotonate solution and butanediol, and carrying out sealed heating and stirring, so as to obtain a mixture A; crushing the gypsum vitreum, mixing the gypsum vitreum with a potassium tartrate solution, and carrying out sealed heating and stirring, so as to obtain a mixture B; and mixing the two mixtures, carrying out ultrasonic treatment, drying, and calcining at 500 DEG C, so as to obtain the air purification material. The air purification material prepared by virtue of the preparation method is capable of removing peculiar smell and eliminating formaldehyde, ammonia, benzene, xylene and the like, the treatment effect is remarkable, and the treatment time is short. The air purification material further has a function of releasing the anions, is capable of purifying the environment, further has the effects of preventing and treating diseases, caring health, opening mind and the like, is suitable for all peculiar smells of various occasions and is applicable to industrial production and large-scale use.
Owner:玛雅森林(北京)国际科技有限公司
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