The invention provides a method for preparing an insulation board. The method comprises the following steps: firstly, adding 4,4'-diaminodiphenyl ether into dimethyl fomamide to prepare mixed solution; mixing sepiolite powder and glass beads, adding the mixture into the mixed solution, uniformly stirring to obtain a mixture; respectively adding triethylamine and aceticanhydride into the mixture, and adding 3,3',4,4'-benzophenone tetracarboxylic dianhydride into the mixture for reaction to prepare a blend; and demolding the blend after the blend is extruded in a mould, and naturally cooling the blend to room temperature to obtain the insulation board. In the method, the sepiolite powder and the glass beads serving as inorganic phases and polyimide serving as an organic phase are adopted to prepare the insulation board which is high-temperature resistant and has long service life. Compared with common insulation materials, by sufficiently utilizing the advantages of corrosion resistance, light weight, low heat conductivity of the sepiolite powder and the glass beads, and high temperature resistance, water prevention, high adhesiveness and the like of the polyimide, the material has the advantages of low heat conductivity, light weight, acid and alkali resistance, corrosion resistance, wide application temperature range and the like, thereby having great market prospect.