The invention discloses sobering-up tea and a preparation method thereof, wherein the sobering-up tea comprises the following raw materials in parts by weight: 10-15 parts of roselle, 10-15 parts of flos pueraria omeiensis, 15-20 parts of penthorum chinense pursh, 5-10 parts of fructus schisandrae chinensis, 5-10 parts of oroxylum indicum, 15-20 parts of calendula officinalis, 10-15 parts of persimmon leaves, 16-22 parts of small red bean flowers, 12-18 parts of verbena officinalis, 8-14 parts of orange peel, 10-15 parts of mung bean flowers, 7-13 parts of shaddock peel, 5-10 parts of rhizoma imperatae, 15-20 parts of broad bean leaves, and 10-15 parts of alpinia katsumadai. The sobering-up tea has double efficacies of inhibiting alcohol absorption and accelerating alcohol excretion, eliminates precipitation of residual alcohol in the liver and the stomach, achieves the sobering-up, liver-protecting and stomach-nourishing purposes, has a quite significant effect of relieving or neutralizing alcohol effects, can quickly eliminate all appearing discomfortableness due to alcohol drinking, effectively prevents drunkenness, and has the advantages of no stimulation, no adverse reaction, safety, reliability, easily available raw materials, and low cost.