29 results about "Polycarbonate membrane" patented technology

The invention discloses a therapeutic nano-vesicle preparation rich in mitochondrial functional protein, a preparation method of the therapeutic nano-vesicle preparation and application of the therapeutic nano-vesicle preparation in treatment of radioactive skin injury. The preparation method comprises the following steps: culturing, amplifying and cleaning umbilical cord mesenchymal stem cells, dispersing the umbilical cord mesenchymal stem cells in a suspension, mechanically extruding the umbilical cord mesenchymal stem cells into a crude solution through a multistage aperture polycarbonate membrane, and centrifuging, concentrating and purifying the crude solution to obtain the preparation. The preparation has the remarkable advantages that local administration can be realized, inflammation can be quickly inhibited, oxidative stress is reduced, and a repair pathway is activated, so that the preparation is suitable for treating acute radioactive skin injury; the preparation method is easy to standardize and scale, high in stability and convenient for emergency storage and delivery, and avoids the defects of cell therapy; a plurality of targets such as immune inflammation, oxidative stress and the like can be synergistically regulated, the biological effect of hUMSCs is simulated and partially replaced, and the limitation caused by the cell survival rate and the microenvironment dependency is avoided; the key function of hUMSCs is covered in function, and the clinical feasibility, safety and emergency suitability of the application level are higher.

The utility model relates to the technical field of myopia prevention and control lenses, in particular to a myopia prevention and control lens, which comprises a resin lens, a central micro lens is fixedly embedded in the middle of the resin lens, an edge micro lens is fixedly sleeved on the circumference of the outer wall of the central micro lens, the edge micro lens is divided into four quadrants, the bottom end of the resin lens is provided with an anti-blue-light layer, the bottom end of the anti-blue-light layer is provided with an anti-ultraviolet layer, the bottom end of the anti-ultraviolet layer is provided with a bonding layer, and the bottom end of the bonding layer is provided with an anti-scratch wear-resistant layer. According to the myopia prevention and control lens, the blue light prevention capability of the lens can be improved and eyes of a user can be protected through the blue light prevention layer made of the blue PET film layer, the eyes can be prevented from being damaged by ultraviolet light through the ultraviolet-proof layer made of the polycarbonate film layer, and the scratch-proof and wear-resistant capability of the lens can be improved through the scratch-proof and wear-resistant layer made of the nano-particle resin layer; the service life of the lens is prolonged.

This invention belongs to the field of polymer membrane material technology and discloses a method for extracting uranium (UO2) from seawater. 2+ This invention discloses a novel separation membrane material, specifically a amine-oxime-modified polycarbonate membrane, its preparation method, and its applications. The invention uses polycarbonate (PC) as a matrix. First, cyano-modified polycarbonate (PCAN) is prepared by grafting cyano groups. Then, PC and PCAN are blended, and a base membrane material is prepared using a phase inversion method. Finally, through in-situ amine-oxime modification, an amine-oxime-modified polycarbonate membrane (PCAO) is obtained, which possesses advantages such as high adsorption capacity, easy recovery, good stability, and excellent recyclability. Furthermore, the polycarbonate membrane modified with amine-oxime groups exhibits highly efficient selective adsorption capacity for uranium, enabling the effective development of uranium resources in seawater. This not only alleviates the domestic shortage of these key energy materials but also significantly improves economic benefits.

The invention provides a hard coating liquid and a preparation method thereof, a hard coating film for an HUD dustproof cover and a preparation method of the hard coating film, and belongs to the technical field of vehicle HUD. The hard coating liquid comprises a resin matrix, the resin matrix comprises a swelling monomer, the swelling monomer comprises at least one of an amide group, a cyclic ether oxygen group and bisphenol A, and the mass ratio of the swelling monomer in the resin matrix is 10 wt%-30 wt%. The swelling monomer containing at least one of an amide group, a cyclic ether oxygen group and bisphenol A is selected and added into the hard coating liquid arranged on the surface of the polycarbonate film, and the swelling monomer has the ability to swell polycarbonate, so that after the hard coating liquid is arranged on the surface of the polycarbonate film, the swelling monomer partially permeates into the surface layer of the polycarbonate, and the hardness of the hard coating liquid is improved. And in the subsequent UV curing process, an interpenetrating network is formed between the polycarbonate surface layer and the hard coating surface layer, so that the prepared hard coating has high hardness, abrasion resistance, solvent wiping resistance and relatively high adhesive force under high temperature and high humidity for a long time.

The application relates to the technical field of composite materials, and discloses a mixed-fiber fabric reinforced thermoplastic composite material laminated plate and a preparation method and application thereof. The laminated plate is obtained by die molding a preformed body, wherein the preformed body comprises a plurality of mixed-fiber fabrics and thermoplastic resin films which are sequentially stacked in layers, and the thermoplastic resin film is selected from one or more of a polyamide film, a polyphenylene sulfide film, a polyether ether ketone film, a poly (aryl ether ketone) film, a polycarbonate film and a polysulfone film. The prepared thermoplastic laminated plate is uniform in resin distribution and excellent in comprehensive mechanical properties.

The utility model discloses a protective device capable of removing a touch screen of an electric control cabinet, the electric control cabinet is provided with a touch screen protruding out of the surface of the electric control cabinet, the protective device comprises a cover body, the cover body comprises a transparent protective film, a positioning frame and a connecting frame which are sequentially arranged from front to back, the transparent protective film is a polycarbonate film or an acrylic acid film, and the connecting frame is a transparent protective film. The positioning frame is arranged at the position, close to the edge, of the rear side of the transparent protective film, the positioning frame is a flexible frame, the connecting frame is a soft magnetic strip frame, a containing space used for containing the touch screen is defined by the transparent protective film, the positioning frame and the connecting frame jointly, and the cover body covers the touch screen and is magnetically attracted to the surface of an electric control cabinet through the connecting frame. The touch screen is located in the containing space of the cover body. Compared with the prior art, the touch screen has the advantages that the touch screen is protected from potential damage such as dust, greasy dirt and cleaning agents, the touch screen can be operated at the same time, and installation and removal are convenient and fast.

The application relates to the technical field of polycarbonate film production, in particular to a polycarbonate film flow coating device. The existing flow coating device is inconvenient for limiting a winding drum, the winding drum is prone to moving during winding, the winding quality is affected, and bulging is prone to occurring during polycarbonate film cooling; after coating is completed, the tail end of the polycarbonate film is prone to being damaged and polluted due to the lack of support. The polycarbonate film flow coating device comprises a base plate and the like; a vertical plate is fixedly connected to the base plate; a winding motor and a rotating motor are fixedly connected to one side of the vertical plate; a forming mechanism is arranged on one side of the vertical plate; and the forming mechanism is connected with the winding motor and the rotating motor. The winding drum is not prone to moving during winding after being limited, and the winding quality is improved.

The utility model relates to the technical field of cell culture, and discloses a biological reaction vessel for in-vitro culture of tissue engineering skin cells, which comprises a liquid storage tank, the top of the liquid storage tank is fixedly connected with a culture bin through supporting legs, and the culture bin is used for culturing cell samples. A plurality of placing grooves are formed in a supporting ring arranged at the top of a culture bin to place polycarbonate films, so that multiple groups of cells can be conveniently cultured by adopting the same culture solution, and floating rods are arranged on the outer walls of the polycarbonate films, so that the polycarbonate films can float on the liquid surface, and the culture efficiency is improved. In order to facilitate the culture mode of skin cells on a polycarbonate film, gas-liquid interface culture is mainly adopted, the gas-liquid interface culture method can realize the multi-layer growth of the cells, the cells in contact with the liquid level of a culture medium have growth and reproduction capabilities in the culture process, and only the cells in contact with air are keratinized, so that the actual growth environment of the skin cells can be simulated, and the skin cells can be effectively cultured. And the cultured data is more referential.

The invention belongs to the technical field of optical devices, and discloses a high-polarization dustproof plate for a vehicle-mounted HUD (Head Up Display) and a preparation method of the high-polarization dustproof plate. The polarization dustproof plate comprises a polarization element sub-layer, a first optical compensation layer and a second optical compensation layer, wherein the polarization element sub-layer is clamped between the first optical compensation layer and the second optical compensation layer; wherein the first optical compensation layer and the second optical compensation layer are both polycarbonate films, and the compensation value Re of the polycarbonate films meets the following relational expression: Re < = 50nm or Re > = 3000nm; the polarizer layer is a polyvinyl alcohol polarizing film, and the degree of polarization of the polyvinyl alcohol polarizing film is larger than or equal to 99%. The optical compensation layers with low compensation value or high compensation value functions are arranged on the two sides of the polarization element sub-layer, and the polarization element sub-layer with high polarization degree is adopted, so that the problems of rainbow lines and ghosting are solved, glare and reflection are reduced, the display definition is improved, and the application requirement of large-size HUD projection display can be met.

The present invention relates to the field of pharmaceutical technology, and in particular, to a daptomycin nano-FORMULATION, a method for preparing same, and use thereof. The method comprises: A, encapsulating daptomycin with a copolymer poly(lactic-co-glycolic acid) to give a nanoparticle (NP); and B, sonicating a cell membrane vesicle overexpressing RANK and the nanoparticle (NP) in a water bath for 3 min, and then sequentially extruding the mixture through polycarbonate membranes of 800 nm, 400 nm, and 200 nm to give the daptomycin nano-formulation. The weight ratio of the membrane protein to PLGA is 0.25. By the method of the present invention, a daptomycin nano-formulation targeting rheumatoid arthritis is successfully prepared. The daptomycin nano-formulation prepared by the present invention has good stability. The daptomycin nano-formulation of the present invention has good therapeutic effects against RA.

The utility model relates to the technical field of polycarbonate film processing, in particular to a polycarbonate film producing and processing device which comprises a processing table, a controller is arranged on one side of the processing table, an installation opening is formed in one side of the processing table, and two connecting frames are symmetrically arranged in the installation opening in parallel. The machining device comprises a machining table, two connecting frames are arranged on the machining table, an adjusting assembly is arranged between the two connecting frames, guiding and shaping assemblies are arranged in the two connecting frames, two guiding assemblies are arranged on one side of the machining table, and the two guiding assemblies are distributed in a high-low structure. Therefore, the distance between the connecting frames can be accurately adjusted, the production requirements of polycarbonate films of different specifications can be quickly met, and the production efficiency and the universality of equipment are improved.

The invention discloses a track etching gradient pore density polycarbonate film and a preparation method thereof, and relates to the field of polycarbonate film preparation, the preparation method comprises the following steps: forming a latent track density gradient on a polycarbonate film a according to a preset pattern by an irradiation method to obtain a polycarbonate film b; etching the polycarbonate film b for the first time by matching an alternating electric field with an etching solution to form an initial hole with a non-circular hole opening and a quasi-circular hole wall, so as to obtain a polycarbonate film c; etching the polycarbonate film c for the second time, and constructing a conical pore channel to obtain a polycarbonate film d; and carrying out termination and post-treatment on the polycarbonate film d to obtain the gradient pore density polycarbonate film. Through the synergistic effect of the gradient hole density, the non-circular hole openings and the conical hole channels, graded interception and internal deep loading of particles are achieved, the long-term operation stability, the impact load resistance and the filtering efficiency of the membrane are effectively improved, and meanwhile the cleaning frequency and the operation cost are reduced.

The invention provides a lutein liposome preparation process for improving bioavailability. The lutein liposome preparation process comprises the following steps: S1, preparing raw materials; s2, preparing a lutein lipid solution: dissolving lutein and a lipid phase in a trichloromethane methanol solution to obtain the lutein lipid solution; s3, forming a thin film: carrying out rotary evaporation on the lutein lipid solution, and removing the organic solvent to form a uniform thin film; s4, preparation and hydration of a composite polyphenol solution: dissolving composite polyphenol in a thermal phosphate solution to obtain the composite polyphenol solution, dropwise adding the composite polyphenol solution into the film for hydration, and performing rotary evaporation to remove an organic solvent to form a uniform film; s5, redissolution and ultrasonic treatment: adding the film into a bile salt solution for redissolution, performing ultrasonic treatment under the ice-water bath stirring condition, and continuing stirring after ultrasonic treatment; and S6, centrifuging and purifying: centrifuging the dispersion liquid to remove unembedded xanthophyll, extruding the dispersion liquid through a polycarbonate film, and removing excessive composite polyphenol through a sephadex column to obtain the composite polyphenol xanthophyll liposome. By adopting the preparation process, the bioavailability of the xanthophyll can be improved.

The application provides a preparation method of autologous cell source nanovesicle loaded miRNA in intervertebral disc degeneration, and steps include: (1) adding miRNA mimics into PBS resuspension of nucleus pulposus cells; (2) using polycarbonate membrane with gradient pore size reduction and NV preparation instrument to extrude the nucleus pulposus cells, and obtaining autologous cell source NV loaded miRNA after sterilization and centrifugation; the autologous cell source nanovesicle loaded miRNA is used in preparation of drugs and complex drugs for treating intervertebral disc degeneration. The application provides a method of autologous cell source nanovesicle loaded miRNA, stress response key miRNA in intervertebral disc degeneration and biological functions thereof are recognized, and autologous nucleus pulposus cell source NV is used to load the stress response key miRNA, effective delivery of miRNA in intervertebral disc is realized, and finally the function of delaying intervertebral disc degeneration under abnormal stress load is played.

This invention provides an ultra-micro agarose gel DNA purification kit and a method for purifying DNA, relating to the field of biotechnology. The kit includes: a sol solution, a purification solution, a washing solution, an elution buffer, an ion adsorption column, and a collection tube. The purification solution comprises 4-6M urea, 2-3M NaCl, and 70%-80% anhydrous ethanol. The ion adsorption column uses a double-layer nanomembrane, with the upper nanomembrane being a polycarbonate membrane and the lower nanomembrane being a polyamide membrane. The kit is low-cost and has high recovery efficiency. This invention also discloses a method for purifying DNA, using a unique buffer system and centrifugal adsorption column method, including steps such as sol-gel, purification, washing, and elution, for the recovery of DNA and PCR products from agarose gel. The method is simple, fast, has high recovery efficiency, and is safe and environmentally friendly.

The invention discloses a construction method of a small intestine organoid and liver organoid co-culture system, and relates to the field of biological tissue engineering, and the construction method comprises the following steps: uniformly spreading a layer of matrigel on a polycarbonate film between a cell cell nesting upper chamber and a cell cell nesting lower chamber, and solidifying to form an isolation layer; the method comprises the following steps: coating mouse small intestine organoid which is just passaged with matrigel, inoculating the mouse small intestine organoid to the bottom of a cell cell nesting upper chamber, adding a small intestine organoid culture medium, and culturing until embryoid bodies are formed and preliminarily germinate; inoculating the matrigel-coated mouse liver organoid to the bottom of the lower chamber of the cell chamber nesting, and waiting until the matrigel is solidified; a liver organoid culture medium is added into the cell cell nesting lower chamber, and a complete cell cell nesting system is placed in a carbon dioxide incubator for continuous co-culture; in the co-culture period, the two kinds of organs can keep good forms, activities and functions, and a reliable in-vitro model is provided for studying intestinal-hepatic axis interaction, drug metabolism, toxicity evaluation and the like.

The invention relates to a preparation method of an anti-inflammatory-cartilage protection double-effect synergistic osteoarthritis microneedle, which comprises the following steps: mixing lecithin, cholesterol, baicalein, naringenin and chloroform methanol to obtain a lipid film, and drying; adding poly (butylene succinate) into the lipid film, hydrating to obtain a liposome suspension, extruding the liposome suspension through a polycarbonate film to obtain a drug-loaded liposome solution, and storing the drug-loaded liposome solution; preparing a mold; adding hyaluronic acid into the drug-loaded liposome solution, uniformly mixing, and pouring into a mold to form a needle body of the microneedle; polyvinylpyrrolidone and polyvinyl alcohol are added into the mold, and a flexible lining plate is formed at the tail of the needle body; and demolding and storing the microneedle. Baicalein and naringenin are jointly loaded into a Baii + Nr microneedle, OA inflammation and cartilage degradation are inhibited at the same time through a complementary mechanism, and synergistic interaction treatment is achieved. Hyaluronic acid is adopted as a matrix, so that the hydrogel has excellent biocompatibility and degradability, and the local drug concentration can be improved.

The invention relates to eye drops based on a boar semen source exosome as well as a preparation method and application of the eye drops, and belongs to the technical field of medicines. The invention relates to a preparation method of eye drops based on a boar semen source exosome. The preparation method comprises the following steps: preparing the boar semen source exosome from fresh boar semen through a differential centrifugation method; mixing carbon quantum dots, manganese dioxide nanoparticles and glucose oxidase, and centrifuging to obtain nano-enzyme; then mixing the obtained exosome with nano enzyme, performing co-extrusion through a polycarbonate film in a liposome extruder to obtain the exosome entrapped with the nano enzyme, and performing incubation and ultrafiltration on the exosome entrapped with the nano enzyme and DSPE-PEG2000-FA to obtain the final eye drops. The exosome derived from the boar semen can reversibly open tight connection in an eye barrier and shows excellent eye infiltration capacity, eye drops prepared by taking the exosome as a carrier can remarkably improve the non-invasive drug delivery efficiency, and the exosome has important significance in promoting development of non-invasive fundus disease treatment.

The utility model relates to a radioactive source technical field especially relates to a kind of alpha instrument scale source and its preparation method.The alpha instrument scale source includes source core and substrate;The source core includes first polycarbonate film and second polycarbonate film, the side of the first polycarbonate film is adsorbed with the precipitate containing radionuclide, the other side of the first polycarbonate film is connected with the substrate by conductive glue, the side of the first polycarbonate film adsorbed with the precipitate containing radionuclide is integrated structure with the second polycarbonate film by hot-press packaging.The novel structure's alpha instrument scale source provided by the utility model is firm in structure, safe and reliable, and excellent in performance, and nuclide universality is good and easy to quantify.

The invention relates to the technical field of radioactive sources, in particular to an alpha instrument scale source and a preparation method thereof. The alpha instrument scale source comprises a source core and a substrate. The source core comprises a first polycarbonate film and a second polycarbonate film, a precipitate containing radionuclide is adsorbed on one side of the first polycarbonate film, and the other side of the first polycarbonate film is connected with the substrate through a conductive adhesive; one side of the first polycarbonate film, which is adsorbed with the sediment containing radionuclide, and the second polycarbonate film are packaged into an integral structure through hot pressing. The alpha instrument scale source with the novel structure is firm in structure, safe, reliable, excellent in performance, good in nuclide universality, easy to quantify, simple in preparation process and high in first-pass yield, and the radiation dose of operators is reduced.

The present invention relates to waterborne coating formulations with polyhedral oligomeric silsesquioxane for hard coating application. The coating composition includes a functionalized polymeric hard coating material, at least one co-polymerizable reactive diluent, a photo initiator or a thermal initiator, and one or more additives. The coating composition can be applied on polycarbonate (PC) film, polyethylene terephthalate (PET) film and paper by conventional coating techniques. The waterborne hard coating features a pencil hardness of more than 4H on PC and PET. The coating developed by internal and external emulsification of POSS which is used as a protective topcoat for various substrates. The resulting coating with high transparency and excellent anti-scratch resistance.

The application discloses a preparation method of an MXene-CMC composite film for salinity gradient energy collection, and specifically comprises the following steps: step 1, preparing an MXene solution; step 2, preparing a CMC solution; step 3, placing the MXene solution prepared in step 1 into the CMC solution prepared in step 2, and dissolving the same through electromagnetic stirring to obtain a mixed dispersion liquid; step 4, taking a polycarbonate film, placing the polycarbonate film as a substrate into a suction filter bottle, taking the mixed dispersion liquid into the suction filter bottle to perform vacuum-assisted suction filtration, and obtaining a polycarbonate film covered with the MXene-CMC composite film; and step 5, stripping the polycarbonate film covered with the MXene-CMC composite film, filtering water, and obtaining the MXene-CMC composite film for salinity gradient energy collection. The application further discloses the MXene-CMC composite film for salinity gradient energy collection. The composite film prepared by the application has the characteristics of high power density, good stability and high economic value.

A water-resistant lens and eyeglasses. The water-resistant lens comprises a substrate layer, an adhesive, and a polarizing lens (500). The substrate layer is made of a polycarbonate film material, the adhesive is a photocurable resin adhesive, and the adhesive is provided between the substrate layer and the polarizing lens (500), such that the substrate layer and the polarizing lens (500) are bonded. In the water-resistant lens, the polycarbonate film material is used as a substrate to replace a traditional cellulose triacetate substrate, and the photocurable resin adhesive is used to replace a traditional water-based adhesive, thereby improving the problem of poor water resistance of traditional multi-layer laminated polarizing eyeglasses.

The application discloses a sea-air interface micro-plastic aerosolization detection system and a detection method. The first box body is a closed box body. An air inlet and an air outlet are arranged on the top cover of the first box body. An overflow pipe is horizontally arranged on the top of the first box body. A horizontal slit is arranged on the overflow pipe. The inlet of the overflow pipe is connected with seawater through a pump. The air inlet is connected with a clean air source. The air outlet is connected with a low-pressure cascade impactor. A first box body overflow port is arranged at a set height of the first box body. The first box body overflow port is sequentially connected with a multi-stage pre-filter and a polycarbonate membrane-glass sand core filter. Aerosol particles generated by breaking waves are collected into an atmospheric particulate matter grading sampler. Micro-plastic particles in seawater and air are identified and counted through different light excitation channels of a fluorescence microscope. Finally, the aerosolization degree of micro-plastics at the sea-air interface is quantified through a micro-plastic aerosolization formula.

The application discloses a preparation method of an oxidized graphene sodium alginate composite film for extracting marine osmotic energy, and specifically comprises the following steps: step 1, preparing a sodium alginate solution; step 2, preparing an oxidized graphene solution; step 3, placing the sodium alginate solution into the oxidized graphene solution, and obtaining a mixed dispersion liquid through electromagnetic stirring; step 4, taking a polycarbonate film, placing the polycarbonate film into a trace suction filter bottle with the polycarbonate film as a base, taking the mixed dispersion liquid into the trace suction filter bottle, and performing vacuum suction filtration to obtain a polycarbonate film covered with the oxidized graphene sodium alginate composite film; and step 5, stripping the polycarbonate film covered with the oxidized graphene sodium alginate composite film, and naturally drying to obtain the oxidized graphene sodium alginate composite film for extracting marine osmotic energy. The application further discloses the oxidized graphene sodium alginate composite film for extracting marine osmotic energy, and the prepared composite film has the characteristics of high power density, good stability and high economic value.

This utility model discloses a forestry ecological restoration monitoring device, relating to the field of forestry ecological restoration monitoring technology. The device includes a column, with a buffer rod slidably connected to the top of the column. A protective box is fixedly installed on the top of the buffer rod, and a supporting frame is fixedly installed on the surface of the protective box. A steel ring is fixedly installed at the end of the supporting frame away from the protective box. A box body is fixedly installed on the surface of the protective box, and a support rod is slidably connected inside the box body. When the support rod moves, a hanging ring slides on the steel ring, thereby unfolding multiple support rods and multiple polycarbonate films. This unfolds the polycarbonate films on the multiple supporting frames and steel rings, thus protecting the monitoring equipment on the column and preventing hail damage to the solar panels and monitoring equipment on the column. This improves the protection of the device, reduces damage to the monitoring equipment during hail weather, and ultimately reduces losses.

The invention discloses a preparation method of bacterial outer membrane vesicle-nano rehmannia polysaccharide for preparing a nano subunit vaccine, and particularly relates to the field of immunobiology. Comprising the following steps: 1, preparing bordetella outer membrane vesicles by adopting an ultrafiltration concentration method; step 2, preparing a nano rehmannia polysaccharide immunologic adjuvant by adopting a film dispersion method and an ultrasonic method; and step 3, mixing the prepared bordetella outer membrane vesicles and the nano rehmannia polysaccharide immunologic adjuvant in an isovolumetric manner, fusing through a nanoparticle extruder provided with a polycarbonate membrane, and extruding back and forth through the extruder to obtain a bacterial outer membrane vesicle-nano rehmannia polysaccharide product. The outer membrane vesicles of the bordetella are prepared by adopting an ultrafiltration method, and the outer membrane vesicles are repeatedly extruded by an extruder and are combined with nano rehmannia polysaccharide to construct the nano subunit vaccine aiming at the bordetella, so that the stability of single outer membrane vesicles is enhanced, and the immune effect of the outer membrane vesicles is improved.

Provided is a multilayer body, and a polarizing plate, a heat-bent molded body, and a lens using the same. The multilayer body has a polycarbonate film having a thickness of 150 to 3000 μm, and a transparent conductive layer containing polyethylene dioxythiophene and polystyrene sulfonic acid.

The invention discloses a preparation method of asiatic acid and curcumin co-loaded liposome, which comprises the following steps: respectively weighing egg yolk lecithin, cholesterol, DSPE-mPEG2k, asiatic acid and curcumin; the preparation method comprises the following steps: dissolving raw material components in a mixed solvent to obtain a first solution; removing the mixed solvent in the first solution by adopting a rotary evaporator, and forming a solid lipid membrane on the inner wall of the round-bottom flask; a phosphate buffer solution is added to the lipid membrane and stirred, so that the lipid membrane is hydrated to form LipoAA / Cur; continuously extruding the LipoAA / Cur through a series of polycarbonate films with different pore diameters by using a liposome extruder; purifying and removing the free medicine by using an ultrafiltration tube to obtain the purified asiatic acid and curcumin co-loaded lipidosome; according to the invention, the common encapsulation efficiency, the drug loading capacity, the solubility and the stability of the asiatic acid and the curcumin can be improved.