The invention provides a multi-layer co-
extrusion packaging material having high 
moisture barrier and barrier properties and a preparation method of the multi-layer co-
extrusion packaging material; and the five-layer co-
extrusion packaging material disclosed by the invention comprises a 
polyethylene layer having 
high intensity and good 
adaptation as the first layer, a 
barrier layer as the second layer, an ultra-fine and ultra-strong water absorbent modified 
polyethylene layer as the third layer, a 
barrier layer as the fourth layer and a high-speed thermal sealing layer having excellent 
chemical stability as the fifth layer, wherein various 
layers are contacted with each other in sequence. In the multi-layer co-extrusion packaging material having high 
moisture barrier and barrier properties disclosed by the invention, the ultra-fine and ultra-strong water absorbent modified 
polyethylene layer has the strong function of absorbing 
moisture; other 
layers respectively have good barrier, thermal sealing and printable properties; in addition, by means of reasonable structural design and 
material selection, various 
layers have excellent packaging material having high 
moisture barrier and barrier properties. The five-layer co-extrusion packaging material disclosed by the invention has excellent 
moisture barrier property; simultaneously, other barrier properties (barrier of 
oxygen, 
nitrogen and the like) are also excellent; furthermore, the cost can be effectively reduced; and the 
processing technique is simple.