The invention discloses a method for refining gamma-TiAl alloy by accurately controlling metastable structure stabilization, the gamma-TiAl alloy comprises the following components in atomic percent: 47.0%-48.5% of Al, 1.0%-2.5% of Nb, 0.0%-2.0% of Cr, 1.0%-3.0% of Ta, 0.01%-0.1% of B and the balance of Ti, and the method comprises the following steps: 1, preparing a gamma-TiAl alloy ingot; 2, carrying out hot isostatic pressing and homogenization treatment; thirdly, heating and heat preservation are conducted in an alpha single-phase region and an alpha + gamma two-phase region in sequence, and the heat treatment process is circulated multiple times; and fourthly, heating and heat preservation are conducted in the alpha single-phase region, and the gamma-TiAl alloy of the fine-grain fully lamellar structure is obtained. According to the method, alloy element adding is combined with circulating heat treatment, the metastable structure is continuously regulated and controlled, grain refinement in the gamma-TiAl alloy is achieved, and the room-temperature plasticity, strength and other performance of the gamma-TiAl alloy are improved.