45results about How to "Reduce anti-aging" patented technology

The present invention is continuous water milling production process of extracting buckwheat starch, buckwheat protein, flavone and dietary fiber. Buckwheat is water soaked, milled into milk and separated in a horizontal sieve to obtain buckwheat slurry and buckwheat dreg; buckwheat slurry is separated continuously to obtain buckwheat starch-I, buckwheat starch-II, buckwheat protein-I, buckwheat protein-II and buckwheat protein-III; and buckwheat dreg is separated to obtain buckwheat protein-IV, flavone and dietary fiber. The present invention obtains eight kinds of product with high additional value from buckwheat, and the production process has less investment, high production efficiency, low cost, no environmental pollution and other advantages.

The invention discloses a preparation method for extracting flavone from purslane and application thereof. The medicine is characterized by a purslane alcohol extract. The preparation method comprises the following steps: 1. cleaning and drying the purslane; 2. cutting the purslane into short sticks; 3. extracting the flavone in the purslane by the reflux of alcohol; 4. performing the pumping filtration on the extracting solution; and 5. concentrating the liquid obtained after pumping filtration. The application method of the extract comprises the following steps: 1. inoculating tumor cells; 2. randomly dividing mice into four groups; 3. performing the group treatment; 4. sampling the blood, and weighing tumor; 5. obtaining blood serum; 6. measuring the content of blood urea nitrogen; and 7. measuring the content of serum creatinine. Animal tests prove that the extract can effectively resist kidney damage caused by the anticancer drug cisplatin; moreover, the extract has the advantages of convenient drug application, good effect and no toxic and side effects; and the purslane is wide in source, and low in price, so that the extract also has the advantages of low price and good quality.

The invention provides low-calorie oat nutrition tablets and a preparation method thereof. The nutrition tablets mainly comprise 35 to 45 parts of original oatmeal, 8 to 15 parts of whole milk powder, 10 to 20 parts of vegetable fat powder, 0.1 to 10 parts of stevioside, 0.5 to 15 parts of erythritol, 5 to 10 parts of maltodextrin, 0.1 to 0.5 part of fresh milk essence and 0.1 to 0.3 part of malt essence. In the invention, the pure natural and zero-calorie stevioside is taken as a sweetener instead of sucrose or an artificial sweetener in an ordinary oat product; and the product can be eaten by diabetics, fat people and crowds who are required to reduce energy intake, has a higher health-care effect, and overcomes the disadvantages of the conventional oatmeal on the market.

The invention discloses a manufacturing method of a cranberry fruit wine, which comprises the following steps: screening out mature and fresh cranberries without diseases; and cleaning, pulping, performing composite enzyme treatment, juicing, filtering, performing yeast fermentation, aging, packaging, and sterilizing to obtain the finished product. According to the invention, a composite enzyme enzymolysis technology is used, the cellulose and hemicellulose decomposition rate of the cranberries is effectively enhanced, and the juice extraction rate of the cranberries is enhanced, thereby better reserving nutrient substances of the cranberries, improving the utilization ratio of the raw material, and ensuring that the fruit wine is rich in fruity flavor, mellow in mouthfeel, stable in color and abundant in nutrition. Besides, the fruit wine has the actions of reducing cardiovascular aging and pathological changes, resisting aging, performing facial care and the like.

The invention provides an artificial sponge soil for urban green space, and relates to the technical field of artificial soil. The artificial sponge soil for urban green space includes a surface layerof buffering pervious bed and a ground layer of aquifer, wherein the buffering pervious bed comprises the following components in a volume ratio: 35%-45% of sandy soil, 20%-30% of industrial and mining waste, 15%-25% of agricultural and forestry waste decomposed substrate, 15%-25% of perlite, 0.5%-1% of granule agent, and 0.5%-1% of stabilizer; the aquifer includes the following components in a volume ratio: 30%-40% of clay soil, 20%-30% of agricultural and forestry waste decomposed substrate, 0.1%-1% of granule agent, 5%-15% of bentonite, 10%-15% of vermiculite, 15%-25% of plant fiber, 0.05%-1% of microbial agent, and 2%-8% of fertilizer; the thickness of the buffering pervious bed is 3 cm to 10 cm; and the thickness of the aquifer is 10 cm to 30 cm. The artificial sponge soil for urbangreen space has the characteristics of strong water permeability, high water storage capacity, good erosion resistance and the like, thus being able to improve the quality of rainwater infiltrated into the soil, reduce pollution to urban groundwater, achieve the purpose of rainwater infiltration, storage and purification, and greatly reduce the high cost of sponge city construction.

The invention relates to the field of health-care food, in particular to nutritional soup and a making method thereof. The nutritional soup is made from, by weight, 120-270 parts of nuts and 100-500 parts of lotus root powder. The nuts and the lotus root powder are reasonably matched and can fully achieve the synergistic effect, and the nutritional soup provides various nutrients for the human body, has the health-care effects of strengthening the brain, protecting heart and cerebral vessels, reducing fire, nourishing blood, tonifying the body, tonifying the spleen and promoting appetite, and is good in taste and easy to digest.

The invention relates to the field of health care food, and particularly provides ginger tea and a preparation method thereof. The ginger tea is prepared from the following raw materials in parts by weight: 5 to 35 parts of ginger, 100 to 260 parts of nuts, 10 to 50 parts of red dates and 50 to 250 parts of brown sugar. According to the ginger tea provided by the invention, the ginger, the nuts, the red dates and the brown sugar are reasonably matched; the synergistic effect can be sufficiently achieved; protein, various vitamins, sugar, grease, mineral substance elements, cellulose and various kinds of trace elements can be provided for the human body; the comprehensive health care effects of replenishing blood, tonifying the kidney, strengthening the brain, warming the stomach, eliminating cold and clearing dampness are achieved; meanwhile, the fatigue can be eliminated; the human body immunity is improved.

The invention provides an edible fungi functional beverage and a preparation method thereof. The edible fungi functional beverage comprises the following raw materials: an edible fungi extracting solution, a Chinese wolfberry extracting solution, a red date extracting solution, a Chinese gooseberry extracting solution, a laminaria extracting solution, honey and purified water. The preparation method comprises the steps of preparation and mixing of the raw materials. The edible fungi functional beverage has the benefits of adjusting human immunity, and supplementing body's vitamin, mineral substances and electrolyte, has the motor functions of reducing consumption and recovering physical strength, can supplement water and nutrient elements fast, is comprehensive in function, and contains no additive, thereby avoiding impact on a human body, protecting people's body health comprehensively, and being suitable for long-term drinking, good in drinking effect, and favorable for popularization.

The invention discloses an edible or health vinegar brewed and distilled from pure grain, which comprises the following parts: 50-70% bran, 20-40% maize, 1-5% rice, 2-10% rice hull and 1-2% yeast. The invention improves the purity without stimulating feeling, which is fit for preparing medical vinegar.

The invention discloses a blueberry coarse cereal-fermented beverage and a preparation method thereof. The blueberry coarse cereal-fermented beverage is prepared from the following components in parts by weight: 60-80 parts of blueberry, 300-400 parts of purified water, 50-60 parts of soybean, 30-40 parts of pearl barley, 20-30 parts of oat, 10-15 parts of yam, 5-10 parts of walnut, 3-5 parts of brown sugar, 3-5 parts of compound protease, 3-5 parts of lactic acid bacteria flora and 1-3 parts of yeast flora. The blueberry coarse cereal-fermented beverage disclosed by the invention is rich in nutrition, has the effects of enhancing the immunity of the human body, reducing blood pressure and blood fat, resisting ageing and the like and is used for effectively preventing cardiovascular and cerebrovascular diseases.

The invention discloses a method for making cranberry fruit wine, and belongs to the field of processing of a beverage. The method is characterized in that a processing technological flow comprising the following steps is adopted: selecting cranberry fruits, cleaning the cranberry fruits, peeling off the cleaned cranberry fruits, trimming the peeled cranberry fruits, blanching the trimmed cranberry fruits, draining off the blanched cranberry fruits, crushing and squeezing the drained cranberry fruits, adjusting juice, blending honey, conducting inoculated fermentation, conducting pre-fermentation, changing a barrel, conducting post-fermentation, aging, filtering, and bottling to obtain a finished product. The method disclosed by the invention has the beneficial effects that the finished product disclosed by the invention is in carmine, and the product is clear and transparent, intense in fruit fragrance, mellow in taste, stable in color and rich in nutrition, and the product reserves the special fruit fragrance and mellow taste of the cranberry fruit wine; the product is rich in various nutrient substances, and the product, as a pure, natural, nutrient and healthy green beverage, has functions of relieving cardiovascular aging and lesion, resisting aging, maintaining beauty and keeping young, and the like. The cranberry fruit wine is easy for storage, convenient to carry, and is suitable for drinking in all seasons.

The invention discloses a functional yoghurt product with the inhibitory activity of alpha-glucosidase and tyrosinase, and a preparation method thereof. The functional yoghurt product is characterizedby performing superfine crushing on fleeceflower root and kudzuvine root, then performing mixing with water, skim milk powder and sugar in a certain proportion, and performing a process of stirring and uniform mixing, filtering, colloid mill emulsification, sterilization, cooling, Lactobacillus plantarum, Lactobacillus acidophilus and Streptococcus thermophilus starter addition, uniform mixing, filling, fermentation, cooling and post-ripening to obtain the yoghurt product with the inhibitory activity of alpha-glucosidase and tyrosinase and the anti-fatigue function. The advantages are that the content of polyphenols and flavonoid aglycones can be significantly increased, the activity of serum glutathione peroxidase, superoxide dismutase and lactate dehydrogenase in mice is increased, andthe content of malondialdehyde and urea nitrogen is reduced.

The invention discloses a high-resveratrol-content nutritional egg. Per 100g of the egg contains 0.3-0.5mg of resveratrol and 2.5-4.5mg of general flavones. A production method comprises the following steps: uniformly mixing and crushing 80 parts of basic ration, 5 parts of seaweed, 2.5 parts of semen cassiae, 2.5 parts of hawthorn, 2.5 parts of selfheal, 2.5 parts of pollen pini, 2.5 parts of grape pip and 2.5 parts of polygonum cuspidatum, fermenting by EM bacteria, then granulating, drying, and supplying the product for chicken in an egg producing period to freely ingest. The egg has multi-aspect health effects on human body.

The invention discloses a pitaya jujube compound jam and a preparation method thereof. Every 100g of mix pulp contains 0-16g of pitaya peel, 5-25g of derris eriocarpa extract, 0-1g of stevioside and 0-8g of lemon pulp. The mixed pulp is made up of pitaya pulp and jujube pulp in mass ratio of (3-7): (3-7). The preparation method comprises the following steps: S1: raw materials selection; S2: cleaning; S3: preparing pitaya pulp; S4: preparing jujube pulp; S5: processing ingredients; S6: mixing and concentrating; S7: filling and sterilization; S8: cooling and packaging and obtaining jam with bestquality by a single factor test under an orthogonal L9 (43) optimization test condition. The test results show that the pitaya jujube compound jam has the optimal mouthfeel and taste in case of 5: 5of mass ratio between the pitaya pulp and the jujube pulp (in 100g of mixed pulp), 12g of added pitaya peel, 15g + 0.5g of ratio between the derris eriocarpa extract and the stevioside and 6g of addedlemon.

The invention provides a weight reducing healthcare product. The weight reducing healthcare product is characterized by being prepared from 15-45 parts of vervain, 15-45 parts of oolong, 10-35 parts of shaddock peel, 8-25 parts of mint leaves and 8-20 parts of lemon grass. The adopted components coordinate to act to jointly achieve the effects of adjusting blood lipid, invigorating the stomach and helping digestion, expelling toxins and beautifying, and promoting urination and relaxing the bowls, and therefore the good effect of eliminating fat and reducing weight is achieved, the weight losing effect is stable, and no side effect exists.

The invention discloses soybean oil capable of resisting ageing and a preparation method of the soybean oil. The soybean oil is prepared from the following components in parts by weight: 1000-2000 parts of soybean oil, 0.01-0.2 part of ginkgo ketone ester, 0.1-20 parts of polyethylene glycol, 2-5 parts of tea polyphenol, 4-10 parts of vitamin E and 0.1-5 parts of lotus leaf extract. By adopting the technical scheme of the invention, the soybean oil has the health care efficacy of resisting ageing except being capable of providing balanced fatty acid.

The invention relates to a multifunctional health product composition. The multifunctional health product composition comprises, by weight, 25-30 parts of nanopowder, 1-3 parts of pyroligneous liquor, 2-6 parts of American ginseng, 10-15 parts of alga extract, 2-6 parts of Agaricus brasiliensis, 2-6 parts of Holy Thistle and 2-6 parts of Gynostemma pentaphylla. The above health product can reduce and avoid human body fatigue, and is especially suitable for diabetic patients. The nanopowder, pumpkin seed shell pyroligneous liquor, American ginseng, Holy Thistle, Agaricus brasiliensis, Codium fragile extract and Gynostemma pentaphylla are compounded to effectively realize reduction and avoiding of human body fatigue.

The present invention discloses mind refreshing and brain benefiting syrup and relates to the technical field of food. The mind refreshing and brain benefiting syrup is prepared from the following raw materials in parts by weight: 3-6 parts of rosemary, 20-40 parts of jasmine flowers, 15-30 parts of chamomile, 20-40 parts of rose flowers, 1-2 parts of mint leaves, 1-2 parts of Chinese wolfberry fruits, 10-20 parts of lemon juice, 200-400 parts of white granulated sugar and 100-200 parts of clean water. The mind refreshing and brain benefiting syrup has the effects of refreshing mind and stimulating brains, enhancing memory, eliminating fatigue, nourishing and protecting skin, and clearing heat and relieving toxins, and also has functions of lowering blood sugar, lowering blood pressure and preventing aging in a regular consumption.

The invention discloses fermented black purslane soy sauce and a preparation method thereof. The fermented black purslane soy sauce is prepared by blending fermented black purslane soy sauce decoction with the conventional soy sauce, wherein the blending ratio of the fermented black purslane soy sauce decoction to the soy sauce is 1:15. The fermented black purslane soy sauce is prepared by the following steps: fermenting purslane under the specific conditions of constant temperature and constant humidity to prepare black purslane; decocting the fermented black purslane into the fermented black purslane decoction; and blending the fermented black purslane decoction with the conventional fermented soy sauce. The product has fragrant flavor and delicious taste, can meet requirements on seasoning and color mixing by people during daily dish cooking, improves the nutritional ingredients of the soy sauce and opens up a new way for application of the purslane. The production process of the product is simple, easy in industrialized production and low in production cost, can form good economic benefit, and is favorable for popularization of the product.

The invention discloses a production method of a pine nut-tea vinegar beverage and relates to the technical field of beverage processing. The pine nut-tea vinegar beverage is prepared from pine nuts, a tea, grosvenor momordica fruits and white sugar. The production method comprises putting the above raw materials into a pot, adding mountain spring water into the pot, carrying out boiling, carrying out cooling, carrying out filtration to obtain extract, inoculating the extract with acetic acid bacteria, carrying out uniform stirring, carrying out sealing fermentation, carrying out acid modulation on the fermented material liquid so that the total acid content of the material liquid is in a range of 0.3g / 100ml-1g / 100ml and soluble solid content is in a range of 3-5%, carrying out disinfection on the material liquid subjected to acid modulation and carrying out vacuum aseptic loading. The pine nut-tea vinegar beverage is a multifunctional beverage with nutrition and health care functions. Extract sweet water of vegetal pine nuts, a tea and grosvenor momordica fruits is used as an acetic acid bacterium medium for fermentation so that plant characteristics are fully performed and various fragrant components and nutrition components are retained. The pine nut-tea vinegar beverage has a delicious taste and an appropriate sour flavor.

The invention provides a formula and making method of tartarian buckwheat milk. Tartarian buckwheat juice obtained through processing tartarian buckwheat, performing residue removal and performing extraction is added and compounded with milk together, and the milk is divided into two kinds of formulas of a pop-top milk formula and a Tetra Pak pack milk formula. The problem of combining the tartarian buckwheat with the milk is solved. A milk beverage which is compounded from the tartarian buckwheat and the milk is made for the first time in the market, so that the milk is rich in mouth feel andgood in taste; on one hand, rich minerals and rich protein of the milk are maintained, and besides, calcium absorption is facilitated; on the other hand, the tartarian buckwheat is also added, can benefit qi and force, benefit ears and eyes, enable qi to flow downwards, ease the intestines, invigorate the stomach, improve body conditions, reduce the attack rate of high blood sugar, high blood pressure and high blood lipid and prevent and treat diabetes, and has definite effects of resisting oxidation, resisting ageing and resisting cancer, so that the tartarian buckwheat milk is suitable forpeople of all ages and both sexes to drink; and besides, the whole making technological process is simple, the production efficiency is high, the making cost is low, and batch production can be realized.

The invention discloses a dietary therapy formula with antioxidant and bacteriostatic effects and capable of enhancing cardiovascular and cerebrovascular functions and human immune function The formula is composed of the following components of soybean glycopeptide, resistant dextrin, maltodextrin, inulin, fructo-oligosaccharide, flaxseed oil microcapsule powder, corn oligopeptide powder, a black fungus extract, a radix puerariae extract, a fructus crataegi extract, a tartary buckwheat extract, cranberry fruit powder, gamma-aminobutyric acid, D-ribose, L-arabinose, taurine, selenium-enriched yeast powder and multivitamins. According to a product with the compound formula, various soybean glycopeptides are used as main raw materials, and various natural pure traditional chinese medicine components are matched for auxiliary use so that the blood pressure and blood fat can be effectively reduced; meanwhile, through antioxidant and bacteriostatic effects, the human immunocompetence can be well improved, and the effects of effectively resisting aging and delaying aging time are achieved; and particularly, by improving the cardiovascular and cerebrovascular functions, the occurrence of diseases caused by cardiovascular and cerebrovascular diseases is inhibited or reduced; and the product is a universal compound beverage product suitable for general drinking of the public.

The invention relates to a traditional Chinese medicine composition, a compound preparation as well as a preparation method and an application of the compound preparation. The traditional Chinese medicine composition comprises raw materials in percentage by weight as follows: 0.19%-0.56% of cordyceps, 2.96%-4.44% of radix panacis quinquefolii, 4.81%-6.30% of carapax trionycis, 1.48%-2.22% of pangolin scales, 4.81%-6.30% of herba dendrobii, 6.67%-8.15% of rhizoma polygoni cuspidati, 2.96%-4.44% of fructus amomi villosi, 2.96%-4.44% of wine-treated rhubarb, 18.52%-25.93% of radix astragali seu hedysari, 1.85%-2.59% of rhizoma coptidis, 2.96%-4.44% of baicalin, 4.81%-6.30% of fructus citri sarcodactylis, 9.63%-12.59% of herba lysimachiae, 6.67%-8.15% of radix paeoniae alba, 0.74%-1.48% of radix notoginseng, 4.81%-6.30% of fructus mori, 2.96%-4.44% of rhizoma dioscoreae and the like. The traditional Chinese medicine composition can treat and prevent hepatic fibrosis.

The invention relates to the technical field of beverage processing and discloses a wild jujube tea vinegar beverage production method. A wild jujube tea vinegar beverage is prepared from wild jujube, tea leaves, fructus momordicae and white sugar. The method includes: putting the raw materials into a pot, adding mountain spring water, boiling, cooling, filtering to obtain extract liquid, pouring the extract liquid into a clean container, performing inoculation of acetic acid bacteria, well mixing, sealing for fermentation, and adjusting acidity of feed liquid to control total acid content of the feed liquid to be 0.3g / 100ml-1g / 100ml and soluble solid content to be 3%-5%; sterilizing the feed liquid subjected to acidity adjustment, and performing vacuum sterile filling to obtain the wild jujube tea vinegar beverage. The wild jujube tea vinegar beverage is a multifunctional beverage integrating nutritional and healthcare functions, and by adoption of vegetable tea leaves and fructus momordicae extract sweet liquid as a acetic acid bacterium culture medium for fermentation, the produced tea vinegar beverage contains various flavor components and nutritional ingredients of tea leaves and fructus momordicae, further has nutritional ingredients and moderate sourness of acetic acid and is excellent in flavor and quality.

The invention relates to the technical field of foods, in particular to a functional plant beverage and a producing method thereof. The functional plant beverage is prepared from, by weight ratio, 20-25 parts of sedum aizoon L. extract, 10-15 parts of a germinated corn germ extracting solution, 12-16 parts of a germinated mung bean germ extracting solution, 15-20 parts of a germinated wheat germ extracting solution, 10-12 parts of a germinated oat germ extracting solution, 10-15 parts of germinated red rice germ extracting solution, 0.01 part of aspartame, 0.01 part of stevioside, 0.03 part of A-K sugar, 0.06 part of citric acid, 0.02 part of sodium citrate and 0.02 part of potassium sorbate. The functional plant beverage contains a variety of active substances having special physiological functions, the content of functional components in the extracting solutions can be increased to the most degree by adopting a germination and extraction method, and the functional plant beverage has cool, refreshing and good taste and is easily absorbed.

The invention discloses a heavy metal resisting type filtering device used for an air cleaner, and an installing and using method thereof. The device comprises a coarse filtration layer, an adsorption layer and a fine filtration layer disposed successively along airflow direction, and also comprises a GSE powder layer, a bacteriostatic and disinfectant layer, a bacillus laterosporus culture medium and a frame; a culture medium installing table is also disposed on the frame while between the coarse filtration layer and the adsorption layer; the bacteriostatic and disinfectant layer is disposed between the adsorption layer and the fine filtration layer; the GSE powder layer is disposed behind the fine filtration layer, and contains a purified water bag wrapped by a hydrophobic gas-permeable membrane; and the bacillus laterosporus culture medium is arranged on the culture medium installing table disposed between the coarse filtration layer and the adsorption layer. The filtering device disclosed by the invention achieves the advantages of excellent gas permeability, high filter capacity and comfort, has the functions of bacteriostasis, disinfection and disease-resistance, can enduringly maintain a negative ion environment suitable for human body, and is beneficial to human health.

The invention discloses a traditional Chinese medicine for treating chronic renal insufficiency. The traditional Chinese medicine is prepared from the following raw materials by weight: 15g of herba epimedii, 20g of fructus lycii, 10g of roasted rhizoma atractylodis macrocephalae, 15g of rhizoma smilacis glabrae, 20g of radix cynanchi paniculati, 20g of raw rhubarb, 10g of pericarpium citri reticulatae, 10g of caulis bambusae in taeniam, 15g of semen plantaginis, 15g of herba leonuri and 9g of radix aconiti lateralis preparata. The traditional Chinese medicine solves the problems that the existing western medicine has no special treatment means for chronic renal insufficiency and is limited to the dilemma of symptomatic support treatment, and is suitable for treating chronic renal insufficiency; and through years of clinical application, the traditional Chinese medicine can quantify urine protein of a patient within 24 hours, reduce the serum creatinine level, increase the endogenous creatinine clearance rate, the erythrocyte count and the hemoglobin level, significantly protect the renal function, reduce the anemia degree of the patient, significantly improve the clinical symptomsof the patient and improve the life quality of the patient.

The invention belongs to the field of building engineering construction and in particular relates to self-adhesive stress cloth. The self-adhesive stress cloth comprises base cloth and a waterproof layer, wherein the base cloth is composed of alkali-free glass fiber yarns and polyester glass fiber cloth. The self-adhesive stress cloth disclosed by the invention can be constructed in autumn and winter or rainy seasons, and the seasonal construction problem is solved; the self-adhesive stress cloth disclosed by the invention is low temperature resistant, normal construction can be performed at atemperature of 0 DEG C or below, and the problem of construction difficulty at a low temperature is solved; the construction efficiency is effectively improved, the construction process is relativelycomplicated in the traditional construction process, while the construction process in the invention is simple; the self-adhesive stress cloth disclosed by the invention has ultrahigh tensile strength, namely two-way tensile strength reaching 50-150KN, and tearing strength, and also has creep resistance, aging resistance and corrosion resistance.

The invention discloses a dry surface modification method for electronic grade super-fine silicon micro-powder, comprising the following steps: selecting super-fine silicon micro-powder with the D50 of 3-50 microns as raw materials; preparing a surface modification mixed solution from the following raw materials by weight percent: 80-90% of silane coupling agent, 6-12% of silane surfactant and 2-8% of polymeric dispersant; heating the raw materials to 80-145 DEG C, and adding the surface modification mixed solution accounting for 0.3-3.0% of the weight of raw materials into the raw materials; carrying out a coating modification on the raw materials; keeping temperature for 30-120 minutes, discharging and cooling to obtain the electronic grade super-fine silicon micro-powder with modified surface. The invention modifies the surface of the super-fine powder, effectively solves the problem of dispersity of the super-fine powder and greatly improves the dispersity, the compatibility of the super-fine powder and an organic polymer i.e. oxygen resin and the binding force of inorganic super-fine powder and organic materials.