The invention provides agilawood toothpaste. The agilawood toothpaste is prepared from agilawood, sarcandra glabra, flos chrysanthemi indici, rhizome imperatae, bamboo salt, almond, Japanese pagodatree juvenile branchlet, cortex moutan, herba violae, honeysuckle flower, flos caryophylli, green tea, root of pseudo-ginseng, leaf of chamomile, herba menthae, radix sophorae flavescentis, chamomile extract, glycerin, calcium titanate, sodium carboxymethylcellulose, sodium lauryl sulfate, sweetening agent, protective agent, stabilizer and deionized water. The agilawood toothpaste disclosed by the invention combines the traditional Chinese medicinal materials with a natural aromatic effect with a modern daily use chemical process, the agilawood is fresh and unique in smell, and meanwhile has the effects of promoting qi circulation to relieve pain, warming middle and arresting vomit, preventing asthma, tranquilizing mind by nourishing the heart, and dredging veins and depressing qi. The agilawood is compatible with other medicine materials to achieve better effects of diminishing inflammation and stopping bleeding, freshening breath and inhibiting dental ulcer. The toothpaste can uniformly and durably release fragrance after being used for tooth brushing; the fragrance is inhaled through the nasal cavity, and then enters a human body through the air exchange of the lung, thereby achieving the effect of treating the disease by smelling fragrance.