The invention relates to a nano intelligent health powder coating. The nano intelligent health powder coating is prepared from the material components: dispersible film-forming materials, inorganic functional element materials, negative ion powder, sea-foam powder, diatomite, titanium dioxide, germanite powder, carbon fiber powder, nano titanium dioxide, nano-silica, nano-zinc oxide, microcapsules, cellulose, dispersan, antifoaming agents and the like; the nano intelligent health powder coating is prepared by the following steps of preparation of activated microporous materials, nano-slurry dispersion and powdering, mixing and stirring, melt extrusion, ball milling separation and sieving and the like; interior wall powder coating, exterior wall powder coating, thermosetting powder coating;in addition to fully complying with national standards, the coating also has new functions of temperature regulation, humidity control, sound insulation, heat preservation, air purification, anti-corrosion, antibacterial sterilization, anti-mold, anti-condensation, anti-radiation, anti-static, permanent release; negative ions, trace elements, far-infrared, bio-current, and permanent adsorption offormaldehyde, benzene, odor, smoke and harmful gases; the coating can be widely used for wall painting of habitable rooms, classrooms, offices, hospitals and the like.