50results about How to "Increase the amount of binding" patented technology

The invention provides a boron and nitrogen co-doping activated carbon which is prepared through utilizing biomass. The boron and nitrogen co-doping chitosan-base activated carbon takes chitosan and boric acid as raw materials, wherein boron in the activated carbon accounts for 1-3wt%, nitrogen in the activated carbon accounts for 4.1-9.2wt%, the specific surface area is 500-1000m<2>/g, and the pore size distribution is 0.46-2nm. The boron and nitrogen co-doping chitosan-base activated carbon takes the chitosan and the boric acid as raw materials and is prepared through co-pyrolysis. According to a method, the combining quantity of the boron in a carbon source and the dispersion degree of the boron in the carbon source are increased under the mutual action of the protonated chitosan and the boric acid, and the boron and nitrogen co-doping chitosan-base activated carbon is obtained through the co-pyrolysis. An environmental-friendly technology for preparing the activated carbon without consuming strong acid and strong alkali is realized, so that a costly and non-environmental-friendly process which consumes a great deal of activating agent and water during the traditional process for preparing the activated carbon is avoided. Moreover, the boron and nitrogen co-doping chitosan-base activated carbon has the advantages of short time consumption, simplicity in preparation technology, simplicity and easiness in equipment and the like.

The invention discloses niraparib granules with a high utilization efficiency and a preparation method thereof, and belongs to the technical field of medicine production. The components of the niraparib granules include niraparib, glucose, vitamin C and a carboxylesterase inhibitor. A granule packaging machine adopted in the preparation method comprises a storage bin and a transparent upper discharge pipe, wherein the transparent upper discharge pipe penetrates through the storage bin, the two sides of the upper discharge pipe are provided with an infrared emitter and an infrared receiver respectively, the infrared emitter and the infrared receiver are capable of lifting and lowering, a turntable is arranged below the upper discharge pipe, a curved through hole is formed in the turntable,a retractable stop block with a proximity switch is arranged on one side of the turntable, and a curved groove is formed in the turntable. By adopting the niraparib granules, the amount of niraparib discharged along with excretion can be reduced, and the pharmacodynamic effect of the niraparib can be maintained; valve-related components of the granule packaging machine adopted in the preparation process of the niraparib granules have longer service life, it can be ensured that the amount of the material discharged each time is sufficient, the remaining granules with a remaining amount less than a set value are remained in the upper discharge pipe, and the application is convenient.

This invention provides an ecological tanning method. The method comprises: pre-tanning with aldehyde tanning agent, tanning with tetrahydroxymethyl phosphonium salt, and then adding collagen to enhance the bonding of the tanning agents. The method utilizes the reaction among aldehyde tanning agent, tetrahydroxymethyl phosphonium salt and collagen to enhance the bonding of the tanning agents as well as increase the shinkage temperature. Besides, the addition of collagen can improve the comprehensive properties of leather and reduce the aldehyde content in leather. The method can be used to replace chrome tannage, thus can avoid the harm of chrome salt to human body and environment.

The invention in particular discloses an EVA (Ethylene Vinyl Acetate) master batch. The EVA master batch is prepared from the following raw materials in percentage by mass: 40 percent to 50 percent of EVA, 30 percent to 40 percent of luminous powder, 1.0 percent to 1.5 percent of kaolin, 2.0 percent to 3.0 percent of a dispersant, 2.5 percent to 4.0 percent of an anti-ageing agent and 10 percent to 12 percent of a compound organic coating agent, wherein the luminous powder is alkaline earth aluminate system long afterglow luminous powder, and the grain size is 12mu m to 20mu m. According to the EVA master batch, a maleic anhydride organic ligand is introduced to the surface of the luminous powder, and the luminous powder more uniformly and densely coats the surface of the luminous powder by utilizing a gemini surfactant, so that contact between the luminous powder and external moisture or metal is reduced, and a product does not turn black; meanwhile, the combination firmness of the luminous powder and the organic ligand is improved, the hydrolyzing resistance of the product and the compatibility between the product and the EVA are greatly improved, and the influences on luminous performance of the luminous powder are very small.

The invention discloses a preparation method of an enzyme immobilization carrier and application of the enzyme immobilization carrier. According to the preparation method of the enzyme immobilization carrier, a polyelectrolyte ball brush is taken as a carrier, an enzyme is immobilized by using a method of carrying out electrostatic adsorption and then carrying out chemical coupling, and the prepared compound is applied to immunoassay. By virtue of the preparation method of the enzyme immobilization carrier, high binding capacity and high activity of the enzyme are achieved; the sensitivity of the enzyme-linked immunoassay can be remarkably improved when the enzyme immobilization carrier is applied to the enzyme-linked immunoassay.

The invention discloses artificial antigen presenting cells and a preparation method and application thereof. According to the preparation method of the artificial antigen presenting cells, a polymermicrosphere surface topological structure morphological control method is established, an antigen presenting function of microspheres is achieved through signal molecule modification, and thus the microspheres can be used for stimulating immune cell amplification and activation. According to the artificial antigen presenting cells, adopted materials have biocompatibility and biodegradability, andthe preparation method of the microspheres with a rough surface structure is easy to operate, environmentally friendly and good in reproducibility.

The invention discloses a method for processing and producing down jackets with aromatic odor. The method comprises the following steps of 1, selecting down feathers, and pre-treating the down feathers, so that micron-sized holes are distributed in the surfaces of the down feathers; 2, selecting essential oil with aromatic smell, and performing high magnetization treatment on the essential oil to make essential oil particles micronized; 3, soaking the down feather treated in the step 1 in the essential oil treated in the step 2, pressurizing a soaking system in the soaking process, separating the down feather after soaking, and naturally airing the down feather; 4, uniformly spraying a mesoporous material on the surface of the down feather treated in the step 3 to form a slow-release coating; and 5, selecting the down feather treated in the step 4, and producing and processing the down feather to obtain the down jacket with aromatic odor. The down jacket prepared by the method can effectively prolong the fragrance emission time, the emission rate is uniform, and the phenomenon that the fragrance is too strong in the early stage is effectively avoided.

The invention discloses a preparation method and applications of a Ni-NTA modified silicon dioxide coated ferroferric oxide magnetic nano functional assembly, and belongs to the field of materials. The preparation method comprises the following steps: preparing Fe3O4 nanoclusters by a solvothermal method; preparing Fe3O4@SiO2 magnetic nanoparticles by a St-ber sol-gel method; adding a silane coupling agent, and carrying out surface carboxylation of Fe3O4@SiO2 (Fe3O4@SiO2@COOH) through a chemical method; introducing an activating agent, and completing NTA modification (Fe3O4@SiO2@COOH@NTA) on the surfaces of the carboxylated Fe3O4@SiO2 magnetic nanoparticles; and adding Ni<2+> to prepare the assembly. According to the invention, the steps are clear, and the prepared magnetic nano functionalassembly is rich in surface groups, large in Ni<2+> binding capacity, high in binding force with His tag protein and high in separation efficiency.

The invention discloses a sensitization test strip for rapidly detecting cronobacter sakazakii and application of the sensitization test strip, and belongs to the technical field of detection of cronobacter sakazakii. The sensitization test strip comprises a sample pad, a gold standard pad, an NC film, an absorbent pad and a bottom plate, wherein the NC film is provided with a detection line and acontrol line, the control line is coated with a goat anti-mouse secondary antibody, and a detection line solution coating the detection line is obtained by incubating colloidal gold and an anti-cronobacter sakazakii capture antibody. The sensitization test strip has the characteristic of being capable of improving the protein binding quantity on the NC film, thereby enhancing the capture rate; the colloidal gold added at the detection line can improve aggregation coloration, thereby improving the detection effect; and the sensitivity is improved by 100 times compared with a traditional test strip, and the sensitization test strip has high specificity, short detection time, easy manufacture and a low cost, and is easy to carry and suitable for on-site detection of cronobacter sakazakii.

The invention provides a printing process, which comprises preparation of anhydrous reactive dye printing paste, printing, drying and aftertreatment. The preparation of the anhydrous reactive dye printing paste comprises the following steps: S1, taking a predetermined amount of dimethylformamide (DMF) and adding a predetermined amount of polyurethane into the dimethylformamide; and S2, taking a predetermined amount of polyurethane solution prepared in the step S1, adding a predetermined amount of reactive dye and a predetermined amount of halogenated hydrocarbon into the polyurethane solutionand continuously stirring for 10 to 30 minutes to obtain the anhydrous reactive dye printing paste. The anhydrous reactive dye printing paste consists of the following components in percentage by weight: 35 to 47.5 percent of dimethylformamide, 2.5 to 15 percent of polyurethane, 0.5 to 1.5 percent of reactive dye and 37.5 to 62.5 percent of halogenated hydrocarbon. Thus, in a paste system of halogenated hydrocarbon/DMF/polyurethane, reactive dye molecules are rapidly pushed and attracted to fiber and then are adsorbed by the fiber at once, and the obtained printing textile product has clear boundary and has high color fastness; and the anhydrous reactive dye printing paste has simple components and is simple in preparation process.

The invention discloses bread rich in litchi bonded phenol and a preparation method thereof The bread comprises the following raw materials in parts by mass: 2 to 25 parts of litchi bonded phenol fruit powder, 1 to 5 parts of dry yeast, 1 to 5 parts of cane sugar, 1 to 5 parts of salt, 40 to 60 parts of egg liquid, 55 to 85 parts of high gluten flour and 200 to 300 parts of water, wherein a preparation method of the litchi bonded phenol fruit powder comprises the following steps of: S1, after peeling, denucleating and cleaning litchis, carrying out juicing, and centrifuging to remove supernatant so as to obtain litchi pomace; S2, carrying out intermittent process and heat pump infrared combined drying on the litchi pomace; and S3, carrying out superfine grinding on the dried litchi pomace to obtain the litchi bonded phenol fruit powder with the particle size less than 500 mum. According to the bread prepared by adopting the litchi fruit powder rich in litchi bonded phenol, which is disclosed by the invention, under the condition of keeping the content of dietary fibers, the content of the bonded phenol in the bread is increased, and the effects of supplementing dietary polyphenol and improving the taste, flavor and water holding capacity of the bread are taken.

The invention discloses tetracycline hollow double-imprinted layer magnetic nanospheres as well as a preparation method and application thereof and belongs to the technical field of preparation of nanomaterials and application in environmental chemistry. The preparation method comprises the following steps: firstly, synthesizing magnetic nanoparticles with a small particle size by using a co-precipitation method at one step; synthesizing silicon spheres by using a method; further adding the silicon spheres, magnetic spheres, dopamine and tetracycline to a Tris-HCl buffer, performing sufficientstirring at room temperature, performing washing, separation and vacuum drying on the product, and repeating a wrapping step; and finally etching off the silicon spheres by using sodium carbonate soas to form a polymer of a hollow structure, separating out the generated polymer by using external magnetic spheres, and performing elution and vacuum drying, so as to obtain the tetracycline hollow double-imprinted layer magnetic nanospheres. The tetracycline hollow double-imprinted layer magnetic nanospheres disclosed by the invention are uniform in particle size, good in structure stability, strong in magnetic responsiveness, good in reusability, large in selective adsorption capacity for tetracycline, large in adsorption capacity, fast in mass transfer rate, high in recovery rate, meanwhile, low in material cost and simple to prepare.

The invention discloses a difunctional monomer testosterone molecularly imprinted magnetic nanosphere with double imprinted layers as well as a preparation method and application of the magnetic nanosphere, and belongs to the technical field of nano-material preparation and nano-medicine. Magnetic nanospheres modified by amphiphilic functional groups are used as carriers, testosterone is used as template molecules, 3aminopropyltriethoxysilane and phenyltrimethoxysilane are used as bifunctional monomers, and the bifunctional monomer double-imprinting-layer testosterone molecularly imprinted magnetic nanospheres are prepared by adopting a method of combining a two-step fixed template and surface imprinting. The difunctional monomer double-imprinting-layer testosterone molecularly imprinted magnetic nanospheres prepared by the method disclosed by the invention are uniform in particle size, good in structural stability, high in selectivity, rich in functional monomer groups and good in biological safety; and the method is a new method for preparing the testosterone molecularly imprinted polymer with high adsorption capacity and high selectivity, the testosterone in cells is removed through full adsorption, the efficiency of castration treatment of the prostate cancer can be remarkably improved, and a new thought is provided for endocrine treatment of the prostate cancer.