227results about How to "Meet the needs of large-scale industrial production" patented technology

The invention discloses a method for preparing thermal-stability perovskite CsPbI3 by a dual-amino organic matter. The method comprises the following steps of dissolving HPbI3, CsI and EDA12 in a DMF solution according to a mole ratio being 1:1:(0.0125-0.05) to obtain a precursor solution A; and spin-coating the precursor solution A on a solar cell substrate, and afterwards performing low-temperature annealing to obtain a perovskite thin film with a smooth surface. Such a type of battery is relatively high in photoelectric conversion efficiency and also is excellent in thermal stability.

The invention discloses an ilicis routundae cortex medicinal composition for preventing and treating alcoholic liver damage, alcoholic fatty liver, non-alcoholic fatty liver and hyperlipidemia. The composition is extracted and refined from natural ilicis routundae cortex and is not chemically modified, and is characterized by comprising substances such as pedunculoside, syringin, rotundicacid and the like. The invention also discloses a preparation method of the ilicis routundae cortex composition and application to preparation of a medicament for preventing and treating the alcoholic liver damage, the alcoholic fatty liver and the non-alcoholic fatty liver and lowering blood fat.

The invention provides a hydrochloric acid-assisted method for preparing an organic and inorganic hybrid perovskite material. The organic and inorganic hybrid perovskite material is prepared through a one-step spin-coating method or a continuous deposition method. The method comprises the following steps: mixing concentrated hydrochloric acid, lead halide PbX2 and corresponding halogenated methylamine MAX at a certain ratio, and then obtaining a high-quality perovskite spin-coating film through spin-coating and annealing; or mixing the concentrated hydrochloric acid with the lead halide PbX2 at the certain ratio and then preparing the high-quality perovskite spin-coating film through spin-coating film formation and soaking growth. By the hydrochloric acid-assisted method, the perovskite film which is good in crystallinity and compact and smooth in surface can be prepared. The preparation method can be carried out at normal temperature, and is convenient to operate, relatively low in cost and good in film-forming property; and large-scale factory production is convenient to achieve.

The invention relates to a method for preparing N<2>-(3-methyl-8-quinoline sulfonyl)- N-nitryl-L-arginine as the intermediate of argatroban. The method comprises the following steps that the reaction of N-nitryl-L-arginine and a 3-methyl-8-quinoline sulfonyl chloride-THF solution is carried out in an aqueous solution of sodium carbonate ; after the reaction ends, THP is collected through evaporation, and the water layer is extracted with an organic solvent, then THF is added with pH adjusted to 2-3, and then a solid saturated water layer of inorganic salt is added; THF is separated and a desiccant is added and stirred for 10-24 hours, with water content of THF measured to be less than 1 percent, then a molecular sift is added for drying, with the water content of THF controlled within 0.2 percent, and then THF reacts with (2R, 4R) 4MPE directly. The invention solves well the control on the water content of N<2>-(3-methyl-8 quinoline sulfonyl)-N N-nitryl-L-arginine, ensures the successful implementation of amide acylation, and satisfies the requirement of the large-scale industrial production.

An instant active whole-value bone powder with nano-class granularity contains collagen (more than 13%), Ca (more than 15%) and minerals (more than 45%). Its preparing process is also disclosed.

The invention belongs to the technical field of biological enzyme engineering, and particularly relates to a nicotinamide riboside kinase mutant with enhanced thermal stability and activity, an encoding gene of the nicotinamide riboside kinase mutant, and application. Compared with wild nicotinamide riboside kinase of which the amino acid sequence is disclosed by SEQ ID NO:4, the amino acid sequence of the nicotinamide riboside kinase mutant is characterized in that one-point or multiple-point combined mutation is carried out on any one or a plurality of sites in 15 pieces of sites of the amino acid sequence disclosed by SEQ ID NO:4. The nicotinamide riboside kinase mutant provided by the invention can be used for synthesis and preparation of [beta]-nicotinamide mononucleotide. Compared with wild enzymes, the nicotinamide riboside kinase mutant constructed by the invention is characterized that the thermal stability and the unit enzyme activity of the mutant are greatly improved, so that the reaction temperature of the enzyme can be obviously improved, a reaction rate is quickened, reaction time is shortened, production cost is lowered, an NMN yield is improved, and the nicotinamide riboside kinase mutant has a wide prospect of large-scale industrial application.

The invention provides a manufacturing method of alloy steel section tubes. The method comprises the following steps: (1) forging steel ingots of alloy steel to a bar material; (2) after removing surface defects of the bar material, cutting the bar material to blank materials with predetermined lengths; (3) drilling the blank materials to manufacture tube blanks; (4) preheating the tube blanks to 600-900 DEG C, and broaching the tube blanks after the tube blanks are heated to 1000-1200 DEG C; (5) after the broached tube blanks are heated to 1100-1300 DEG C, performing extrusion molding to obtain the section tubes. By adopting the manufacturing method of the alloy steel section tubes, the production process can be simplified, the production cost can be largely reduced, the requirements of large-scale industrial production can be met, and the section tubes with the good quality are obtained.

The invention discloses a cabazitaxel intermediate as well as a preparation method and an application thereof. The intermediate has a chemical structure formula shown as formula I shown in the description, and TES in the formula is the abbreviation of triethylsilane. The preparation method of the intermediate comprises a step B or a step A and the step B in the following synthetic route shown in the description, wherein the step A means that the compound of a formula 1 is subjected to a methylation reaction with a methylation agent for preparation of the compound of a formula 2; and the step B means that the compound of the formula 2 is subjected to a condensation reaction with the compound of a formula 3 for preparation of the intermediate I. The intermediate is subjected to hydrolysis under an acidic condition for removing the triethylsilane protective group, and thus cabazitaxel is prepared. According to the technical scheme, high-purity cabazitaxel can be synthesized by utilizing cheap and easily-available raw materials and with a low cost, large-scale industrialized production requirement on cabazitaxel is satisfied, and the preparation method is applicable to industrial application and has practical value.

The present invention relates to a cake richly containing complete animal bone powder. It includes flour for making cake and additive, in which the animal bone powder is added. It is characterized by that its calcium content is high, and its animal bone powder grain size is up to nano-grade, so that it contains rich nutrients.

The present invention relates to a flavouring material richly containing animal bone powder. It is characterized by that in the flavouring material the nano-grade animal bone powder is added, so that its nutrients are rich and its calcium content is high.

The invention relates to a high-purity ammonium hydroxide absorption device and technology, and discloses an ammonia absorption device formed by high-purity materials. The high-purity ammonium hydroxide absorption device comprises a liquid ammonia tank, an ammonia gas deoiling device, an ammonia gas degranulation device, an ammonia absorption device and an ultra-clean high-purity ammonium hydroxide storage tank which are sequentially connected. The invention further discloses a method for preparing the ultra-clean high-purity ammonium hydroxide. The ammonia absorption device and the method for preparing the ultra-clean high-purity ammonium hydroxide have the advantages that the ultra-clean high-purity ammonium hydroxide can be prepared, the device is simple in structure, the number of needed processing procedures is small, the absorption is fast, the yield is high, the energy is saved, the efficiency is high, three wastes cannot be discharged, the requirement for environmental protection is met, the demand for industry large-scale manufacturing is met, and the device has good application value.

A boxing production line for a packing bag relates to a boxing production line and comprises a stand as well as a chain plate type conveying mechanism, a first driving mechanism, a packing bag extruding and boxing mechanism and a second driving mechanism which are respectively mounted on the stand, wherein the packing bag extruding and boxing mechanism comprises synchronous worktables, a packing bag removing mechanism, a packing bag extruding mechanism and a packing bag boxing mechanism; the synchronous worktables can be longitudinally mounted on the stand along the stand in a sliding way and are positioned on the front side and the back side of the chain plate type conveying mechanism; the second driving mechanism is connected with the synchronous worktables; and the packing bag removing mechanism, the packing bag extruding mechanism and the packing bag boxing mechanism are respectively mounted on the synchronous worktables. According to the boxing production line disclosed by the invention, the packing bags can be automatically finished and counted; the bagging bags with the preset quantity are arranged into a row; one row of packing bags are extruded and subjected to width reduction and are loaded into the packing box for work; and in addition, the work efficiency is greatly improved, the labor force can be greatly saved and the production cost is effectively reduced.

The invention provides a method for improving stability of a perovskite film through sulphuring treatment. The perovskite film is processed by sulfur-containing inorganic salts to form a protection layer on the surface of the perovskite film, thereby improving stability of the film. The method comprises the following steps: applying a solution containing sulfur ions to a lead halide perovskite film under a certain condition, and then, carrying out annealing processing to obtain the perovskite film wrapped by the lead sulfide. The method can improve humidity resistance and stability of the perovskite film obviously, and has great significance to practical application.

The invention relates to an extraction process of traditional Chinese medicine, in particular to an extraction process of polysaccharide in poria cocos. The extraction process of polysaccharide in poria cocos is low in time consumption and high in extraction rate. The extraction process includes the process steps of performing pretreatment; performing extraction, wherein distilled water is added into degreased poria cocos powder at the material-liquid ratio of 1:15-1:25, and ultrasonic extraction is performed for 25-30 min at 60-80 DEG C at the ultrasonic power of 200-280 w; performing suction filtration, decoloration and concentration; performing deproteinization, wherein crude polysaccharide is dissolved in double-distilled water, the mixture is added into mixed liquor of chloroform and n-butyl alcohol at the mass ratio of 4:1-5:1 after even mixing, the ratio of m chloroform to m n-butyl alcohol in the mixed liquor is 5:1, supernatant liquor is taken after shaking, 3-5-volume fold ethyl alcohol with the mass fraction of 95% is added, the mixture is placed in a refrigerator for 24 h of standing, and then deproteinized poria cocos polysaccharide is obtained through centrifugation; performing washing to obtain poria cocos polysaccharide.

The invention belongs to the field of biological medicament, and specifically relates to a NDM-1 type metallo-beta-lactamase tripeptide inhibitor with an amino acid sequence of Phe-Cys-D-Phe. Pharmacodynamical experiments prove that the peptide provided by the invention is applicable to preparation of antibacterial medicaments for preventing and treating drug-resistance bacterial infection.

The invention relates to an electron cyclotron resonance (ECR) plasma sputtering device and discloses a cavity structure of the ECR plasma sputtering device, which is capable of conveniently changing particle sources. The cavity structure comprises a left vacuum cavity (1), a right vacuum cavity (2) and at least two target cavities (3, 4); wherein, the target cavities (3, 4) are connected between the left vacuum cavity and the right vacuum cavity (1, 2) and are internally provided with targets. The cavity structure is characterized in that a washer (5) is arranged between adjacent target cavities (3, 4) and is provided with a driving rod (17) in the radial direction; the inner end of the driving rod (17) is provided with a gear (18); a sliding check ring (15) is arranged in the adjacent target cavities (3, 4); the outer wall of the check ring (15) is inlaid with a rack (16) in the axial direction; the rack (16) is meshed with the gear (18) and a dynamic sealing equipment is arranged between the washer (5) and the driving rod (17).

The invention provides a method for preparing simple and controllable nanoscale silver-loaded monox. The method comprises the specific steps that (1) monodispersed spherical nanometer SiO<2> particles are prepared through a Stober method; (2) a reducibility group is decorated on the surface of a nanometer SiO<2> sphere; (3) silver particles with the diameter of 1-3 nm are reduced on the surface of the nanometer SiO<2> sphere. The obtained silver-loaded monox is regular in form and even in particle size, and the particle size and density of the silver particles on the surface of the silver-loaded monox can be regulated and controlled easily; the overall preparation technology is easy and feasible, a product system is stable, and the industrial preparation potential is achieved.