113results about How to "Prevent hyperglycemia" patented technology

The invention discloses a method of increasing the content of resistant starch in rice through genome editing and sgRNA special for the same. The method provides a method of increasing the content of resistant starch and/or amylase in rice seeds. The method includes the following steps that expression of SBEIIb genes in the rice is inhibited; the SBEIIb genes are genes of encoding SBEIIb protein. The invention further provides a method of increasing the content of resistant starch in rice and includes the step of inhibiting the activity of the SBEIIb protein in the rice. By using the CRISPR/Cas9 technology, the rice SBEIIb genes are edited at fixed points, the rice SBEIIb genes are knocked off by causing frameshift mutation, and the new generation of new rice germplasm with the content of amylase and resistant starch obviously increased is obtained.

The invention discloses a culture method of black fungus rich in seabuckthorn flavonoids and a culture medium thereof and relates to the culture method of the black fungus and the culture medium thereof. The culture method can solve the problems that the hyphae growth speed during the culture process by using the existing culture method is slow, and the content of total flavonoids of the obtainedblack fungus is low. The method is as follows: 1, preparing the culture medium; 2, carrying out high-pressure or normal-pressure damp heat sterilization after bagging and sealing the culture medium, and then carrying out natural cooling; and 3, inoculating a black 29 secondary strain into a bacterial bag after cooling, then disinfecting the bacterial bag, cutting an opening, carrying out centralized germination and growing management, harvesting till a fruiting body of the black fungus grows to 80% of mature and drying in the air, thereby obtaining the black fungus rich in seabuckthorn flavonoids. The obtained black fungus rich in seabuckthorn flavonoids can effectively treat and prevent hypertension and hyperglycemia, suppress platelet aggregation and heart failure and increase the healthcare effect of the black fungus. The hyphae growth speed during the culture process is fast. The obtained product has high yield.

The invention relates to a glede tea beverage and a preparation method thereof. According to the preparation method, glede tea, which accounts for 0.6 to 0.8 percent of the total weight of the beverage, is crushed into tea powder, sieved by a 50-mesh sieve and then weighed. After that, water accounting for 8 to 10 times of the weight of the glede tea powders is added into an extraction tank, heated to 75 to 90 DEG C at the room temperature, added with the tea powders for stirring extraction for 8 to 12 minutes. Then the materials are filtered by a filter screen being 200 to 300 meshes to obtain filter liquid (1). Water accounting for 4 to 6 times of the weight of the filter residue is adopted for extracting for 4 to 6 minutes under the same conditions of the filter residue. The filtering operation is carried out by the filter screen being 200 to 300 meshes to obtain filter liquid (2). The filter liquids (1) and (2) are merged and added into the extraction tank. The filter liquid is heated to 60 to 80 DEG C and the pressure thereof is reduced the to -15kPa to 20kPa for concentration. Condensed liquid, i.e. aromatic water, is collected. The collecting of the condensed liquid is stopped until the weight of the condensed liquid is 1 to 1.5 times of that of the tea powder. Then concentration is continuously carryed out until the weight is 1/4 to 1/3 of the total filter liquid weight. The spray drying is carryed out to obtain dry powder. The prepared dry powder, the aromatic water, the white granulated sugar and the citric acid are mixed and prepared. The glede tea beverage has the advantages that the tea beverage has the effects of relieving summer heat and quenching the thirst, helping digestion and enhancing the human body immunity, the quality is easy to control, and in addition, the taste is good.

The invention relates to an isulin analogue having quick response and stability under acidic condition, and a medicinal composition and a medicinal preparation thereof. Asparagine (Asn) at the A 21 position of the chain A of the isulin analogue is mutated into glycine (Gly), the isulin analogue can be mixed with a long-acting isulin analogue such as insulin glargine to form a premixed preparationwith two functions of quick-acting sugar reduction and stable long-acting sugar reduction, and the problems that the conventional natural insulin (of pigs, cows and human) and quick-acting isulin analogues are unstable in the acidic environment, and the conventional isulin premixed preparation is not clarified and needed to be introduced with a foreign protein (such as protamine) serving as a slow release preparation so as to easily cause immune reaction, and is needed to be injected twice each day, namely in the morning and evening are solved, so that the safety of the preparation is higher.

The invention provides a production method of an original kudzu vine root product and products of the production method. The production method comprises the following steps of: peeling cleaned kudzu vine root, cleaning by spring water with the temperature below 10 DEG C whiling peeling, collecting washing liquor to obtain original kudzu vine root liquid, placing the peeled original kudzu vine root for about 12h at the temperature below 10 DEG C, slicing into kudzu vine root pieces, drying the kudzu vine root pieces till the water content is less than 13%, cutting up to the kudzu vine root pieces, smashing through a screen of 500 meshes, screening to obtain original kudzu vine root fiber finished product, smashing the screened kudzu vine root semi-finished product again, screening through a screen of 80 meshes to obtain original kudzu vine root fiber powder, and screening through a screen of 120 meshes to obtain the original kudzu vine root product. After the invention is used, the temperature, the moisture and the time are controlled, the structure can be broken without the application of an external force, the activation and the decomposition of the cell bud can be avoided, the loss of the original substance of the kudzu vine root can be controlled, and the original kudzu vine root product is guaranteed to have the original quality, original taste, and edible, health-care and medical components of the kudzu vine root. On the same production line, the plurality of original kudzu vine root products can be produced and processed.

The invention relates to a novel compound propolis preparation and a preparation method thereof. The compound propolis product is prepared form the following ingredients: supercritical propolis, supercritical perilla frutescens seed oil, supercritical glossy ganoderma spore oil and ethanol extracted supercritical propolis residue. A main technical method has the following steps: removing impurities from raw materials; pulverizing raw materials; carrying out CO2 supercritical extraction; preparing microcapsule emulsion; carrying out vacuum freeze drying; carrying out pulverization; stirring and mixing all ingredients; and carrying out sterilization, capsule filling and package. The product of the invention belongs to the health care food with higher nutritional value, and has various health care effects of blood pressure reduction, blood fat reduction, antioxidation, immunity improvement and the like.

The invention provides corn stigma effervescent tablets which comprise the following components in parts by weight: 30-40 parts of sodium hydrogen carbonate, 30-35 parts of citric acid, 15-20 parts of corn stigma extract, 5-10 parts of starch and 3-5 parts of magnesium stearate. The corn stigma effervescent tablets are made by the steps of sieving, premixing, pelleting, granulating, tabletting and packaging. The corn stigma effervescent tablets have the functions of relieving summer heat and clearing heat as well as mitigating edema and inducing diuresis, and also can be used for preventing diseases such as hyperglycemia, hyperlipidemia, hypertension, etc.

A method of treating and preventing type 2 diabetes and obesity an animal, including mammals and humans, in which a therapeutically effective amount of catalpic acid to the animal is administered orally or parentally.

The invention belongs to the field of quick-frozen food industry, and particularly relates to tartary buckwheat sweet dumplings capable of controlling blood glucose and a making method. The mass dosage ratio of sweet dumpling wrappers to sweet dumpling stuffing is (1.5-3.5):1; the sweet dumpling stuffing is made from 25%-45% of maltitol, 15%-30% of sesame seeds, 205-30% of vegetable oil, 5%-15% of common wheat flour, 8%-15% of water and 0.2%-10% of olive oil, wherein the percentage content sum of all the components is 100%; the sweet dumpling wrappers are made from 45%-75% of glutinous rice flour, 20%-50% of tartary buckwheat powder, 2.5%-10% of wheat starch and additives comprising, by total mass of the glutinous rice flour, the tartary buckwheat powder and the wheat starch, 2%-10% of vegetable oil, 0.1%-2.5% of wheat dietary fiber powder, 0.5%-0.75% of a quick-frozen sweet dumpling modifying agent and 55%-80% of water. The sweet dumplings are soft, glutinous, fine and smooth in mouthfeel, fragrant and sweet in sesame seed stuffing and low in blood glucose increasing index and can effectively help a diabetic patient to better control the postprandial blood glucose.

The invention relates to a low-sugar tea oil emulsion and a preparation method, belonging to the technical field of modern agricultures. The preparation method comprises the following steps of: respectively heating a component A and a component B to 50-90 DEG C, adding the component A into the component B, stirring for 25-40 min, adding a component C after naturally cooling to 25-40 DEG C, stirring and mixing, and cooling to room temperature so as to obtain uniform emulsion. Compared with the prior art, a technological method by using the emulsion and Chinese herbal medicine combined emulsified tea oil is provided; therefore, novel use of the tea oil is developed; and simultaneously, the nutritional components of the low-sugar tea oil are increased and the effects of lowering blood pressure, blood fat and blood glucose are also achieved.

The invention provides a Litsea coreana sugar-free buccal tablet, which comprises a Litsea coreana extract, vitamin C, mint, dextrin, xylitol and stervioside. The preparation method comprises the following steps: (1) crushing Litsea coreana into tea powder, screening by a sieve of 60 meshes, respectively extracting the screened Litsea coreana powder by ethanol and water, concentrating and spray drying to prepare the Litsea coreana extract; (2) mixing the Litsea coreana extract, vitamin C, mint, dextrin, xylitol and stervioside according to weight percentage for granulating; (3) pressing the buccal tablet and packaging. According to the invention, the Litsea coreana sugar-free buccal tablet is capable of effectively developing the application field of Litsea coreana, the traditional liquid tea of Litsea coreana is changed into a novel tea drinking method-tea buccal tablet taking. The Litsea coreana buccal tablet has the effects of relieving heat and quenching thirst, promoting and eliminating indigestion, detoxifying, deswelling, promoting the urination, improving eyesight, strengthening stomach and brainstorming, and is capable of enhancing the immunity of human body and resisting electromagnetic radiation, and also can be a health product for preventing and treating hypertension, hyperlipemia and hyperglycemia.

The invention discloses a drug for treating diabetes and hyperlipidemia, in particular to the drug which takes Chinese herbal medicines as a formula for treating diabetes and hyperlipidemia. The invention adopts the following technical proposal: a traditional Chinese medicine for treating diabetes and hyperlipidemia takes gynura root as a monarch drug and takes gynostemma pentaphyllum as a minister drug, the dose is 2.8-3.3: 1 by weight percentage for compatibility, and the optimal formula is that the dose of the gynura root and the gynostemma pentaphyllum is 3: 1 by weight percentage for compatibility. The drug has great effects for more than 80 percent of patients with type II diabetes and significant effects for preventing and treating a variety of complications caused in late stage of the diabetes; the effects for the patients with high blood sugar and hyperlipidemia are even better, and more than 80 percent of people do not need to take any other drug.

The invention relates to the field of nutritional functional foods and provides an instant food capable of preventing and lowering hyperglycemia, hyperlipidemia and hypertension, and specifically relates to an instant food capable of preventing and reducing the hyperglycemia, the hyperlipidemia and the hypertension. The instant food is prepared by mixing oats, barley, wheat, buckwheat, rye, tartary buckwheat, inulin, L-arabinose, polydextrose, xylooligosaccharide, a fructus momordicae charantiae extract, a fructus lycii extract, a hawthorn extract, a radix puerariae extract, a grosvenor momordica fruit extract, a mulberry leaf extract, a ginkgo extract, rhizoma dioscoreae powder, pumpkin powder, barley seedling powder, rivier giantarum rhizome powder and a compound nutrient. The instant food is rich in nutrition, can regulate blood sugar, blood fat and blood pressure, can well promote metabolism of a human body, is beneficial to intestinal health, is matched according to the traditional Chinese medicine principle and a dietary nutrition rule, does not have the hypersensitivity and toxic or side effects and is safe and reliable after being eaten.

The invention discloses a kind of leather shoes for losing weight and preventing three highs, which comprises a sole and an insole. The upper surface of the sole is provided with several elastic massage bodies, and the elastic massage bodies are arranged corresponding to different acupoints on the soles of the feet. Massage magnet, the top surface of the massage magnet is 4-16mm higher than the top surface of the elastic massage body, the insole pad is arranged on the sole, and the lower surface is provided with the same number and corresponding positions as the elastic massage body. The pits cover the elastic massage body and the massage magnet. The present invention stimulates the acupuncture points on the soles of the feet corresponding to various parts of the body through the elastic massage body and the massage magnet, which can promote blood circulation, accelerate metabolism, and expedite the elimination of toxins and wastes deposited around the tissues. The role of lipids and hyperglycemia.

It has been found that an extracellular polypeptide derived from Akkermansia municiphila is capable of modulating and/or promoting gut mucosal immune system function and/or maintaining and/or restoring metabolic status and/or increasing the physical integrity of the gut mucosal barrier in a mammal. The polypeptide or host cells including such polypeptide may be employed to prevent and/or treat a variety of conditions that benefit from an increased physical integrity of the gut mucosal barrier and/or an improved gut mucosal immune system function and metabolic status.

The invention discloses new long-acting GLP-1 (glucagonlike peptide-1) compounds, a medicine composition containing the compounds, wherein the compound is used for (1) treatments of hyperglycemia, type 2 diabetes, type 1 diabetes, impaired glucose tolerance, obesity, hypertension, X syndrome, dyslipidemia, cognitive disorder, myocardial infarction, coronary heart disease and other vascular diseases, apoplexy, dyspepsia and gastric ulcer, (2) or reducing food intake and beta-cell apoptosis, enhancing beta-cell function and beta-cell quantity , and or, recovering the glucose sensitivity of beta-cell.

The invention belongs to a mechanical harvesting processing technology for husbandry, namely a harvesting and processing technology for producing high-quality ultra-micro edible alfalfa powder. In order to solve the problems of low nutritious value, high fiber content, pollution and mold caused by cutting, raking and turning, picking and chopping, and transport in a full-plant alfalfa harvesting and processing technology for producing high-quality alfalfa powder, and problems that nutrients are lost, fibers are coarse and large, the digestion rate is low and the product is only suitable to serve as a feed caused by high temperature processing and a common crushing method, the technology adopts a head cutting and non-landing harvesting and loading and transporting mode; and after alfalfas are cut, the heads of the alfalfas containing rich nutrients are cut off and pressed into square bundles, the square bundles are directly loaded and transported to a processing factory, and the heads of the alfalfas are subjected to solar low temperature drying, chopping, airflow ultra-micro low temperature crushing and microwave low temperature sterilization treatment to form the high-quality ultra-micro edible alfalfa powder which is pollution-free and mold-free, effectively maintains bioactivity and nutrients of fresh alfalfas, contains rich dietary fibers, has good water solubility and mouthfeel, is easy to digest and absorb, and has the fineness of 150-200 meshes.

The invention discloses a liver-clearing, cholagogic and detoxifying electuary. The electuary comprises 8 to 15 parts of Cyclea hypoglauca, 2 to 4 parts of gynostemma pentaphylla, 2 to 4 parts of Mussaenda philippica, 1 to 3 parts of giant knotweed rhizome, 1 to 3 parts of silvervine, 0.5 to 1.5 parts of licorice, 1 to 3 parts of Indian damnacanthus herb and 1 to 3 parts of Polygala fallax Hemsl. The invention further discloses a preparation method for the liver-clearing, cholagogic and detoxifying electuary. The method comprises the following steps: respectively crushing Cyclea hypoglauca, gynostemma pentaphylla, Mussaenda philippica, giant knotweed rhizome, silvervine, licorice, Indian damnacanthus herb and Polygala fallax Hemsl into fine powder with a size of 120 meshes; and uniformly mixing the powders obtained in the previous step according to respective weight parts so as to obtain the liver-clearing, cholagogic and detoxifying electuary. The liver-clearing, cholagogic and detoxifying electuary is hermetically soaked in water with a temperature of 80 to 100 DEG C for 10 min before drinking, has heat-clearing, dampness-draining, detoxifying, liver-clearing, cholagogic, diuresis-inducing and strangury-freeing effects and can prevent hypertension, hyperlipidemia and hyperglycemia after long-term drinking of the electuary.

The invention discloses a sea-buckthorn pleurotus citrinopileutus culture medium which comprises the following components in parts by weight: 40-50 parts of sea-buckthorn saw dust, 5-15 parts of sea-buckthorn fruit dregs, 25-35 parts of crushed corncobs, 10-14 parts of wheat bran, 0.5-1.5 parts of corn meal, 0.5-1.5 parts of lime and 0.5-1.5 parts of gypsum. According to the culture medium, human nutrients and pleurotus citrinopileutus nutrients contained in the sea-buckthorn fruit dregs and the sea-buckthorn saw dust are organically combined together under the action of microorganisms to obtain pleurotus citrinopileutus rich in sea-buckthorn flavone; the pleurotus citrinopileutus rich in sea buckthorn flavone can be used for treating and preventing hypertension, hyperglycemia and cardiac failure and restricting the platelet aggregation, and the health function of the pleurotus citrinopileutus is increased.

The invention discloses a solid drink for preventing senile dementia. The solid drink is prepared from the following components in parts by weight: 10-15 parts of a food composition, 50-75 parts of corn flour, 20-30 parts of sweet potato flour, 3-8 parts of non-dairy creamer, 5-8 parts of citric acid, 2-3 parts of CMC-Na and 5-10 parts of a natural sweetener, wherein the food composition includes the following components in parts by weight: 10-20 parts of garlic extract, 5-15 parts of porphyra haitanensis extract and 2-8 parts of kudzuvine root extract. The solid drink provided by the invention is formulated through scientific and reasonable compatibility of the components and has the advantages of a reasonable formula, high pertinence, relatively good taste, easy consumption, high digestibility, easy absorption and good brewing performance. The solid drink has the efficacy of effectively delaying aging, preventing the senile dementia, etc. and is greatly suitable for the middle-aged and elderly people to take.

The invention discloses application of phellinus linteus polysaccharides in the field of the preparation of medicines and health care food. The product has the functions of lowering the levels of fasting blood-glucose and insulin, improving liver phospholipid balance and the one carbon unit metabolism of a human body and enhancing insulin sensitivity. The product can be used for treating or preventing chronic metabolic diseases including insulin resistance, hyperglycemia, hyperinsulinemia, type 2 diabetes, fatness, non-alcoholic fatty liver, high blood pressure, hyperlipidemia and the like.

The present invention relates to a semen trichosanthis oil emulsion and a preparation method thereof, and belongs to the technical field of modern agriculture. The semen trichosanthis oil emulsion includes the following components in weight proportions: semen trichosanthis oil 20%-45%, solvents 47%-57%, emulsifiers 10%-30%, aromatic agents 0.5%-1.5%, flavoring agents 0.5%-1.5% and antiseptic agents 0.5%-1.5%. The preparation method comprises the following steps of firstly, adding the semen trichosanthis oil into a blending kettle, then proportionally adding the solvents into the blending kettle, and stirring and dissolving the mixture, under the normal temperature condition; and then successively and proportionally adding the emulsifiers, the aromatic agents, the flavoring agents and antiseptic agents into the blending kettle, and fully and evenly stirring and mixing the mixture, thereby obtaining the semen trichosanthis oil emulsion. The semen trichosanthis oil emulsion can prevent and treat high blood pressure, high blood sugar and high blood lipids, and is characterized in that the semen trichosanthis oil emulsion is high in bioavailability and convenient to use.

Aiming at the problem of inconvenience in subcutaneous injection and administration of liraglutide in the prior art, the invention provides an alternative liraglutide administration mode, on one hand, the invention provides a polypeptide composition, and the polypeptide composition comprises a therapeutically effective amount of polypeptide, N-(8-(2-hydroxybenzoyl) amino) caprylate and fish oil. On the other hand, the invention provides application of the polypeptide composition in preparation of drugs for treating or preventing hyperglycemia, type 2 diabetes mellitus, type 1 diabetes mellitus, obesity and glucose tolerance reduction.