The invention discloses a book printing production technology and a book printing production line, and relates to the technical field of book printing. The production line comprises a bookblock manufacturing assembly, a book cover manufacturing assembly and an adhesive binding machine, the bookblock manufacturing assembly comprises a bookblock printer, a folding machine and a collating machine, the collating machine is connected with the adhesive binding machine, the book cover manufacturing assembly comprises a book cover printer and a paper cutting machine, and further comprises a mark folding device connected with the paper cutting machine, the mark folding device comprises a rack and a supporting sheet, and the rack is provided with a middle seam folding assembly and an adhesive-binding face folding assembly; the middle seam folding assembly comprises a connecting plate and a pressing plate, and the connecting plate is provided with a measuring assembly; and the adhesive-binding face folding assembly comprises two indentation plates, an abutting plate is arranged at the end, away from the indentation plates, of the supporting sheet, two positioning plates are arranged on the two sides of the abutting plate, a crossbeam is fixed to the upper end of the rack and provided with a sliding groove, and the abutting plate and the pressing plate are slidably connected to the slidinggroove. Binding of bookblocks and covers is facilitated, generation of defective books is effectively reduced, and the phenomenon of waste of raw materials is reduced.