7 results about "Ethylamine hydrochloride" patented technology

This invention discloses a highly selective method for preparing triethylenetetramine. The method uses 2-chloroethylamine hydrochloride and ethylenediamine as raw materials, reacting them in an aqueous solution. An aqueous solution of ethylenediamine with a concentration of 1-100 wt% is added dropwise to an aqueous solution of 2-chloroethylamine hydrochloride with a concentration of 1-100 wt%. The dropping rate of the ethylenediamine solution is 5% to 100% of its own mass per hour. The reaction temperature is 30-200 °C (oil bath temperature), and the reaction time is 2-20 hours (including the dropping time). The molar ratio of 2-chloroethylamine hydrochloride to ethylenediamine is 2:1 to 40:1. This invention is the first to propose a direct synthesis of triethylenetetramine from the bulk chemicals 2-chloroethylamine hydrochloride and ethylenediamine. Compared with the previously reported dichloroethane amination method and the nucleophilic substitution method between dichloroethane and ethylenediamine, this method offers milder reaction conditions, simpler operation, and higher selectivity, making it suitable for industrial production.

The application belongs to the technical field of electrolysis of water, and particularly relates to a NiFe bimetallic MOF self-supporting bifunctional electrode for electrolysis of water and a method for electrolysis of water. The electrode takes foamed nickel as a substrate, and the surface of the substrate is uniformly coated with NiFe bimetallic MOF. The coating method comprises the following steps: two pieces of foamed nickel after cleaning and pretreatment are taken as anodes, one piece of foamed nickel after cleaning and pretreatment is taken as a cathode, and the anodes and the cathode are immersed in an electrolyte; under the condition of a constant current of 14-16 mA of a direct current power supply, electrodeposition is performed for 15-55 min; the area of the anode foamed nickel is larger than that of the cathode; in the electrolyte, N,N-dimethylformamide is taken as a solvent, and nickel salt, iron salt, 1,3,5-benzene tricarboxylic acid and triethylamine hydrochloride are uniformly dissolved in the solvent; the molar ratio of Ni to Fe is 40-75:1; and the concentration of triethylamine hydrochloride is 0.01-0.1 mol L⁻¹. The application adopts a double-anode electrodeposition process to improve deposition uniformity, fully expose active sites and reduce electrodeposition energy consumption; and the synergistic effect of the Ni-Fe bimetallic MOF optimizes the HER and OER catalytic performance of the electrode.

This invention provides a method for preparing androstane-3,6,17-trione (E,Z)-3-[O-(2-aminoethyl)]oxime hydrochloride, comprising the following steps: benzophenone oxime reacts with 2-chloroethylamine hydrochloride in dimethyl sulfoxide, followed by acid-base adjustment, toluene extraction, hydrolysis with concentrated hydrochloric acid to remove the protecting group, and crystallization to obtain high-purity 2-aminoethylamine hydrochloride; androstane-3,6,17-triol is used as a raw material and oxidized under the catalysis of sodium bromate and ruthenium oxide (IV), quenched, separated, washed with water, and crystallized by solvent replacement with isopropanol to obtain androstane-3,6,17-trione; the 2-aminoethylamine hydrochloride solution is mixed and reacted with the trione in tetrahydrofuran solution at low temperature, followed by salting out, filtration, separation, washing with saturated brine and drying with magnesium sulfate, and purification by solvent replacement, water dissolution and concentration, and cooling crystallization to obtain the high-purity target product. This invention significantly improves the yield of the target product by optimizing reaction conditions, while achieving readily available raw materials, low cost, and industrialized production through traditional chemical reaction pathways.

The application discloses a method for producing berberine by using recycled formic acid, and belongs to the technical field of preparation of medical chemical raw materials. The method comprises the following steps: 1, adding diatomite powder to a dilute hydrochloric acid solution to remove impurities, and preparing a water removing agent by acid pickling, roasting and dropwise adding phosphorus oxychloride; 2, adding anhydrous sodium sulfate to crude formic acid to pre-dehydrate, adding the water removing agent to remove water after filtering out the precipitate, and obtaining refined recycled formic acid; 3, adding copper chloride, refined recycled formic acid, N-2,3-dimethoxybenzyl piperidyl ethylamine hydrochloride into a reactor, dropwise adding 40% glyoxal, and performing cyclization reaction for 3-4 hours; 4, removing the cyclization mother liquor by suction filtration, retaining the solid, adjusting the alkali and heating, filtering out the precipitate and retaining the filtrate, adjusting the acid, cooling and crystallizing, filtering and retaining the solid, rinsing and drying, and obtaining berberine. The application realizes preparation of berberine by using recycled formic acid, and the production process is safe, and the product has high purity and high yield.

This invention discloses a method for recovering triethylamine hydrochloride and treating wastewater, aiming to solve the problems of recovering vinylene carbonate and triethylamine while reducing the cost of waste treatment. The method includes: Step 1: Soaking triethylamine hydrochloride in an organic solvent, ultrasonically cavitating and pulverizing the triethylamine hydrochloride, dissolving vinylene carbonate, filtering, and drying the triethylamine hydrochloride in stages under reduced pressure to recover vinylene carbonate and triethylamine; Step 2: Mixing the triethylamine hydrochloride with diatomaceous earth and subjecting it to high-temperature heat treatment; Step 3: Dissolving the heat-treated mixture of triethylamine hydrochloride and diatomaceous earth in water, filtering, alkaline hydrolysis, phase separation, and wastewater extraction; Step 4: Using an adsorbent to adsorb the wastewater, resulting in effluent with TOC < 10 ppm and TN < 5 ppm, which can be directly discharged into the sea after meeting the standards. Compared with traditional wastewater evaporation and salt precipitation operations, this method significantly reduces wastewater treatment costs. The recovered vinylene carbonate, after desolventizing and purification, can be sold as a product.

The application discloses a preparation process of berberine hydrochloride and belongs to the technical field of berberine production. The preparation process of the berberine hydrochloride comprises the following steps: S1, mixing iron sulfate-aluminum sulfate composite salt, sodium chloride, zinc chloride and anhydrous formic acid to pre-activate, adding N-2,3-dimethoxybenzyl piperidyl ethylamine hydrochloride, and dropwise adding a glyoxal mixed solution to perform reflux reaction; S2, cooling the reaction solution to precipitate solids, filtering, stirring the filter cake and diatomite in pure water, adjusting alkalinity, continuously stirring for 0.5-1 hours after temperature rising, cooling and filtering, and reserving the filtrate; S3, adjusting the filtrate to be acidic, cooling and crystallizing, filtering, rinsing the filter cake, vacuum drying the filter cake to obtain the berberine hydrochloride. The berberine hydrochloride prepared by the application has high yield and high purity, the preparation process is safe, the process is short, and the application is friendly to human bodies and the environment.