15 results about "Ethylamine hydrochloride" patented technology

The invention discloses a preparation process of berberine hydrochloride, and belongs to the technical field of berberine production. The invention relates to a berberine hydrochloride preparation process, which comprises: S1, mixing a ferric sulfate-aluminum sulfate composite salt, sodium chloride, zinc chloride and anhydrous formic acid, pre-activating, adding N-2, 3-dimethoxybenzyl homopiperony lamine hydrochloride, dropwise adding a glyoxal mixed solution, and carrying out a reflux reaction. And S2, cooling the reaction liquid until a solid is separated out, filtering, adding a filter cake and diatomite into purified water, stirring, adjusting alkali, heating, and continuously stirring for 0.5-1 hour. Cooling and filtering, and reserving filtrate; s3, adjusting the acidity of the filtrate, cooling and growing crystals; and filtering, rinsing a filter cake, and carrying out vacuum drying on the filter cake to obtain berberine hydrochloride. The berberine hydrochloride prepared by the method is high in yield and purity, and the preparation process is safe, short in flow and friendly to human bodies and environment.

The invention discloses a methylamine-free perovskite thin film with high thermal stability and a preparation method of the methylamine-free perovskite thin film. The perovskite thin film is prepared from an FAPbI3 perovskite precursor solution doped with 2-(methylsulfonyl) ethylamine hydrochloride. A proper amount of 2-(methylsulfonyl) ethylamine hydrochloride is added into the perovskite precursor solution, the compact and uniform FAPbI3 perovskite thin film with photovoltaic activity is obtained under the condition that methylamine ions are not introduced, the thin film has excellent thermal stability, the service life of a perovskite solar cell can be prolonged, and the service life of the perovskite solar cell is prolonged. And the positive significance is realized on the commercialized application of the perovskite battery.

According to the invention, a novel ternary acidic deep eutectic solvent (DES) is prepared, ethylamine hydrochloride (EH) is used as a hydrogen bond acceptor (HBD), and DL-malic acid (MA) and polyethylene glycol-400 (PEG-400) are used as hydrogen bond donors (HBA). The DES solvent has good performance on wood fiber biomass refining pretreatment, and three major components of lignocellulose can be efficiently separated. The ternary acidic DES disclosed by the invention is easy to synthesize, good in stability and simple in use method, and an ideal separation effect can be achieved when high biomass solid content is treated, that is, most cellulose is reserved in a solid form, and most hemicellulose and lignin are converted into a liquid form through dissolution or partial degradation to be separated; and separating the lignin component from the hemicellulose by anti-solvent precipitation. The prepared DES can be recycled after being filtered and subjected to rotary evaporation, still has a separation effect equivalent to that of an original solvent after being recycled for six times, and has good industrial application prospect and value.

This invention discloses a highly selective method for preparing triethylenetetramine. The method uses 2-chloroethylamine hydrochloride and ethylenediamine as raw materials, reacting them in an aqueous solution. An aqueous solution of ethylenediamine with a concentration of 1-100 wt% is added dropwise to an aqueous solution of 2-chloroethylamine hydrochloride with a concentration of 1-100 wt%. The dropping rate of the ethylenediamine solution is 5% to 100% of its own mass per hour. The reaction temperature is 30-200 °C (oil bath temperature), and the reaction time is 2-20 hours (including the dropping time). The molar ratio of 2-chloroethylamine hydrochloride to ethylenediamine is 2:1 to 40:1. This invention is the first to propose a direct synthesis of triethylenetetramine from the bulk chemicals 2-chloroethylamine hydrochloride and ethylenediamine. Compared with the previously reported dichloroethane amination method and the nucleophilic substitution method between dichloroethane and ethylenediamine, this method offers milder reaction conditions, simpler operation, and higher selectivity, making it suitable for industrial production.

The application belongs to the technical field of electrolysis of water, and particularly relates to a NiFe bimetallic MOF self-supporting bifunctional electrode for electrolysis of water and a method for electrolysis of water. The electrode takes foamed nickel as a substrate, and the surface of the substrate is uniformly coated with NiFe bimetallic MOF. The coating method comprises the following steps: two pieces of foamed nickel after cleaning and pretreatment are taken as anodes, one piece of foamed nickel after cleaning and pretreatment is taken as a cathode, and the anodes and the cathode are immersed in an electrolyte; under the condition of a constant current of 14-16 mA of a direct current power supply, electrodeposition is performed for 15-55 min; the area of the anode foamed nickel is larger than that of the cathode; in the electrolyte, N,N-dimethylformamide is taken as a solvent, and nickel salt, iron salt, 1,3,5-benzene tricarboxylic acid and triethylamine hydrochloride are uniformly dissolved in the solvent; the molar ratio of Ni to Fe is 40-75:1; and the concentration of triethylamine hydrochloride is 0.01-0.1 mol L⁻¹. The application adopts a double-anode electrodeposition process to improve deposition uniformity, fully expose active sites and reduce electrodeposition energy consumption; and the synergistic effect of the Ni-Fe bimetallic MOF optimizes the HER and OER catalytic performance of the electrode.

This invention provides a method for preparing androstane-3,6,17-trione (E,Z)-3-[O-(2-aminoethyl)]oxime hydrochloride, comprising the following steps: benzophenone oxime reacts with 2-chloroethylamine hydrochloride in dimethyl sulfoxide, followed by acid-base adjustment, toluene extraction, hydrolysis with concentrated hydrochloric acid to remove the protecting group, and crystallization to obtain high-purity 2-aminoethylamine hydrochloride; androstane-3,6,17-triol is used as a raw material and oxidized under the catalysis of sodium bromate and ruthenium oxide (IV), quenched, separated, washed with water, and crystallized by solvent replacement with isopropanol to obtain androstane-3,6,17-trione; the 2-aminoethylamine hydrochloride solution is mixed and reacted with the trione in tetrahydrofuran solution at low temperature, followed by salting out, filtration, separation, washing with saturated brine and drying with magnesium sulfate, and purification by solvent replacement, water dissolution and concentration, and cooling crystallization to obtain the high-purity target product. This invention significantly improves the yield of the target product by optimizing reaction conditions, while achieving readily available raw materials, low cost, and industrialized production through traditional chemical reaction pathways.

The invention discloses an integral centrifugal column for enriching S-nitrosopeptide as well as a preparation method and application of the integral centrifugal column, and belongs to the technical field of SNO proteomics analysis. The method disclosed by the invention comprises the following steps: adding an integral material pre-polymerization solution into a closed blank centrifugal column, and carrying out in-situ thermal initiation polymerization reaction to obtain a substrate integral material centrifugal column; and swelling the substrate integral material centrifugal column, adding a phosphate buffer solution of pyridine dithio ethylamine hydrochloride, standing and cleaning to obtain the integral material centrifugal column for enriching the SNO peptide. The centrifugal column can realize integrated reduction, marking and enrichment of SNO peptides, and is applied to SNO proteomics analysis in complex biological samples. The method solves the technical problem that the existing method is difficult to simultaneously reduce / mark / enrich SNO protein or peptide in a complex sample, effectively reduces the loss and degradation of the SNO peptide in the sample treatment process through the integrated sample treatment process, and obviously improves the identification scale of the SNO protein and the modification site.

The invention discloses metal surface anticorrosive paint and a preparation method thereof, and relates to the field of metal anticorrosive paint. When the metal surface anticorrosive paint is prepared, modified castor oil and triethylamine hydrochloride react to prepare a castor oil-based cross-linking agent; the preparation method comprises the following steps: carrying out epoxidation reaction on hexafluorobisphenol A and epoxy chloropropane to prepare an epoxy prepolymer; reacting the epoxy prepolymer with protocatechuic acid to obtain modified epoxy resin; the preparation method comprises the following steps: reacting 2-aminobenzothiazole with isocyanate propyl triethoxy silane to prepare modified silane; and uniformly mixing the modified epoxy resin, the modified silane and the mixed solvent, and adding the flatting agent and the castor oil-based cross-linking agent to prepare the metal surface anticorrosive paint. The metal surface anticorrosive paint prepared by the invention has excellent corrosion resistance, antibacterial property and high adhesive force.

The application discloses a method for producing berberine by using recycled formic acid, and belongs to the technical field of preparation of medical chemical raw materials. The method comprises the following steps: 1, adding diatomite powder to a dilute hydrochloric acid solution to remove impurities, and preparing a water removing agent by acid pickling, roasting and dropwise adding phosphorus oxychloride; 2, adding anhydrous sodium sulfate to crude formic acid to pre-dehydrate, adding the water removing agent to remove water after filtering out the precipitate, and obtaining refined recycled formic acid; 3, adding copper chloride, refined recycled formic acid, N-2,3-dimethoxybenzyl piperidyl ethylamine hydrochloride into a reactor, dropwise adding 40% glyoxal, and performing cyclization reaction for 3-4 hours; 4, removing the cyclization mother liquor by suction filtration, retaining the solid, adjusting the alkali and heating, filtering out the precipitate and retaining the filtrate, adjusting the acid, cooling and crystallizing, filtering and retaining the solid, rinsing and drying, and obtaining berberine. The application realizes preparation of berberine by using recycled formic acid, and the production process is safe, and the product has high purity and high yield.

The invention discloses an acid-base bifunctional solid catalyst and a synthetic method of chlorphenesin, and belongs to the technical field of organic chemical preparation. The acid-base bifunctional solid catalyst is prepared by the following steps: 1) dispersing UiO-66-NH2 in dimethylformamide, adding 2-chloroethylamine hydrochloride, and carrying out a reaction, so as to obtain imidization modified UiO-66-NH2; 2) dispersing the imidization modified UiO-66-NH2 in methanol, adding formaldehyde, and carrying out a reaction to obtain a solid product; and 3) dispersing the solid product in acetonitrile, adding hypophosphorous acid, and carrying out a reaction to obtain the acid-base bifunctional solid catalyst. When the acid-base bifunctional catalyst provided by the invention is used for synthesizing chlorphenesin, the catalyst is easy to recover, environment-friendly and non-corrosive to production equipment, the loss of raw materials and equipment can be effectively reduced, and side reaction can be effectively inhibited.

This invention discloses a method for recovering triethylamine hydrochloride and treating wastewater, aiming to solve the problems of recovering vinylene carbonate and triethylamine while reducing the cost of waste treatment. The method includes: Step 1: Soaking triethylamine hydrochloride in an organic solvent, ultrasonically cavitating and pulverizing the triethylamine hydrochloride, dissolving vinylene carbonate, filtering, and drying the triethylamine hydrochloride in stages under reduced pressure to recover vinylene carbonate and triethylamine; Step 2: Mixing the triethylamine hydrochloride with diatomaceous earth and subjecting it to high-temperature heat treatment; Step 3: Dissolving the heat-treated mixture of triethylamine hydrochloride and diatomaceous earth in water, filtering, alkaline hydrolysis, phase separation, and wastewater extraction; Step 4: Using an adsorbent to adsorb the wastewater, resulting in effluent with TOC < 10 ppm and TN < 5 ppm, which can be directly discharged into the sea after meeting the standards. Compared with traditional wastewater evaporation and salt precipitation operations, this method significantly reduces wastewater treatment costs. The recovered vinylene carbonate, after desolventizing and purification, can be sold as a product.

The utility model discloses a triethylamine hydrochloride wastewater pretreatment device, which relates to the technical field of wastewater pretreatment and comprises a stirring tank. A first motor for driving the rotating shaft to rotate is mounted at the top of the stirring tank, a stirring part is mounted on the outer side of the rotating shaft and close to the bottom, a purification box for pretreating wastewater is mounted on the other side of the stirring tank, and a filtering part is mounted on the inner side of the purification box through multiple groups of locking fasteners; according to the sewage treatment device disclosed by the utility model, large-particle impurities in sewage are filtered and purified in advance through the filtering piece in the purification box, and a purified aqueous solution is pumped into the stirring tank by utilizing the liquid pump; the stirring piece is used for fully stirring and mixing the aqueous solution and the medicine, the PH value adjusting speed is increased, the brushing piece can be used for brushing and cleaning the filtering piece, impurity accumulation is avoided, and the filtering piece can be taken out, disassembled, replaced or fixedly installed through the locking piece.

The invention belongs to the field of organic chemistry, and particularly relates to a synthetic method of berberine hydrochloride. The method comprises the following steps: taking 3, 4-dimethoxyphenylethylamine hydrochloride and 3, 4-methylenedioxybenzaldehyde as starting raw materials, carrying out three-step reaction in sequence, sequentially carrying out oxidative cyclization, selective reduction and quaternization ring closing, and finally directly obtaining the target product berberine hydrochloride through acid treatment. The technical scheme has the characteristics of high efficiency, simplicity and high industrial cost performance in synthesis of berberine hydrochloride, the whole reaction is green and safe, the reaction conditions are mild, the reaction process has extremely high selectivity, and a berberine hydrochloride product with higher purity can be obtained.

The application discloses a preparation process of berberine hydrochloride and belongs to the technical field of berberine production. The preparation process of the berberine hydrochloride comprises the following steps: S1, mixing iron sulfate-aluminum sulfate composite salt, sodium chloride, zinc chloride and anhydrous formic acid to pre-activate, adding N-2,3-dimethoxybenzyl piperidyl ethylamine hydrochloride, and dropwise adding a glyoxal mixed solution to perform reflux reaction; S2, cooling the reaction solution to precipitate solids, filtering, stirring the filter cake and diatomite in pure water, adjusting alkalinity, continuously stirring for 0.5-1 hours after temperature rising, cooling and filtering, and reserving the filtrate; S3, adjusting the filtrate to be acidic, cooling and crystallizing, filtering, rinsing the filter cake, vacuum drying the filter cake to obtain the berberine hydrochloride. The berberine hydrochloride prepared by the application has high yield and high purity, the preparation process is safe, the process is short, and the application is friendly to human bodies and the environment.