53results about How to "Prevent Mutual Aggregation" patented technology

The invention discloses a drug-loaded saccule and a manufacture method thereof. The drug-loaded saccule comprises a saccule with a multivalve structure, wherein a drug-coated crystal layer is adhered to the surface of the saccule, and comprises an active drug and a drug mixture; the content of the active drug in the drug-coated crystal layer is gradually reduced from the surface of the saccule outward, while the content of the drug mixture is gradually increased from the surface of the saccule outward. The manufacture method comprises the following steps: firstly, folding the surface of the saccule; preparing drug-coating solutions with different proportions by using the active drug, the drug mixture and solvent as raw materials; then, sequentially coating the drug-coating solutions to the surface of the saccule according to a decreasing sequence of the content of the active drug, drying and crystallizing to obtain a multi-layer drug-coated crystal layer having the content of the active drug in a gradient descending shape inside-out; and finally, rolling and pressing the saccule to obtain the final drug-loaded saccule. The drug-loaded saccule has an excellent drug-loading performance, strong adhesion soundness and strong washing resistance.

The invention discloses a regulator for the growth of compound nutritional plants. The growth regulator consists of microelements of 3.2 to 6.0wt percent, medium elements of 2.3 to 3.6wt percent, trace elements of 3.79 to 6.25wt percent, organic complexing agent and surfactant. The regulator for the growth of the compound nutritional plants overcomes the various shortages of the existing plant yield stimulants with single function and has the advantages of plant growth regulator, multiplex trace elements fertilizer, anti-drought agent and anti-photosynthesis agent. Through experiments for a plurality of years and promoting demonstrations, the regulator for the growth of compound nutritional plants is proved to have yield promotion effect on all grain crops, economic crops, fruits and vegetables and flowers and trees with evident and stable growth rate of yield and safe use but no toxic side effect, no residues and no contamination.

The invention relates to a method for synthesizing powder of cadmium selenide quanta dots capable of emitting blue light, belonging to the technical field of processing nanometer inorganic compound material of semiconductor. With cadmium acetate dehydrate and sodium selenite as raw material, disodium ethylenediamintetraacetate as chelating agent, and in the aqueous solution with weak alkaline, cadmium selenide quanta dots are synthesized by being radiated by electron beams. The powder of cadmium selenide quanta dots is obtained after separating the synthesized product. The cadmium selenide powder prepared by the invention has extremely good water solubility, good monodispersity, and even size with an average particle size of three nanometers. The cadmium selenide powder emits blue light, has good fluorescence characteristics and is used for manufacturing biological fluorescence probe.

The invention discloses a method adopting linear poly N-isopropyl acrylamide adhesive to assist the renaturation of muramidase in vitro, comprising the following steps that: 1) the linear N-isopropyl acrylamide is prepared by a free radical polymerization method; 2) the linear poly N-isopropyl acrylamide is used to assist the renaturation of muramidase in vitro. The linear poly N-isopropyl acrylamide is taken as a novel protein in vitro additive which can increase the processing concentration of the renaturation muramidase, lower the production cost, and improve the activity recovery rate of the muramidase up to about 80 percent when the processing concentration is 600 Mug/mL; while the activity recovery rate of the dilution renaturation on the same condition is only 10 percent. The gel has the advantages of high efficiency, convenient operation and simple technique, etc., thereby having good potential application in the protein in vitro renaturation field.

The method for assisting lysozyme renaturation with temperature-sensitive poly N-isopropyl acrylamide gel includes the following steps: 1) compounding poly N-isopropyl acrylamide gel aqua; 2) preparing poly N-isopropyl acrylamide gel in reverse suspension process; and 3) assisting lysozyme renaturation with temperature-sensitive poly N-isopropyl acrylamide gel. The temperature-sensitive poly N-isopropyl acrylamide gel the present invention develops as one novel additive for extracorporeal renaturation of protein can raise the lysozyme activity recovering rate. The gel has high efficiency, less renaturation affecting parameters, convenient operation, relax requirement in instrument and apparatus, easy separation and recovery and other advantages. The present invention has excellent application foreground in extracorporeal renaturation of protein.

The invention discloses a method for preparing high-activity Pd nano particle-supported carbon nano catalyst by diglycol reduction process. In the method, diglycol is used as a solvent and a reducing agent, and Pd nano particle-supported carbon catalyst is obtained. Pd nano particles in the prepared catalyst are uniformly dispersed and average particle size is 2-5 nm; moreover, electro-catalytic property of the catalyst to methyl alcohol is obviously improved, and the catalyst has excellent electro-catalytic property and stability. The preparation method is simple and easy in operation, is energy-saved and environmental-friendly, has no pollution, high economic benefit and is very applicable to industrial large-scale production.

The invention discloses a method for preparing cationic polyacrylamide emulsion in an aqueous dispersion polymerization manner. The preparation method comprises the following steps: dissolving nonionic monomers, cationic monomers, a dispersion stabilizer, parital inorganic salts and additives in deionized water, stirring in a constant-temperature water bath at 40 to 70 DEG C to form a homogenous system, introducing nitrogen to remove oxygen, adding an initiator accounting for 50 to 80 percent of the total weight of an initiator raw material, continuously reacting for 3 to 6 h, adding the remaining initiator, then reacting, and adding the remaining inorganic salts, continuously stirring, thus obtaining the cationic polyacrylamide emulsion. A novel oxidization reduction initiator system is applied, the graphene oxide is used as a reducing agent, persulfate is used as an oxidant, and the cationic polyacrylamide emulsion is prepared by virtue of the aqueous dispersion polymerization method. The emulsion prepared by the method has the characteristics of instant solubility, high molecular weight, good mobility, good stability, no organic solvent in the polymerization process, environmental friendliness, nontoxicity, capability of adsorbing trace heavy metal ions and the like.

The invention provides an anticorrosive coating. The anticorrosive coating is composed of a component A and a component B, wherein based on 100% of the total mass of the component A, the component A comprises the following components in percentage by mass: 40-60% of graphene modified magnesium powder, 20-40% of epoxy resin, 0.6-3% of a dispersing agent, 2-10% of a filler, 0.5-5% of an anti-settling agent and 5-20% of an organic solvent; and based on 100% of the total mass of the component B, the component B comprises the following components in percentage by mass: 50-70% of a curing agent, 20-40% of an organic solvent, 1-10% of a coupling agent and 0.5-5% of a curing accelerator. The anticorrosive coating provided by the invention has strong adhesion to a base material, is not easy to falloff from the surface of a base material, and plays a good role in protecting the base material; and the coating has good salt water resistance, water resistance, salt mist resistance and acid and alkali resistance, and achieves a good anti-corrosion effect.

The invention provides methods for preparing and applying a high performance hydrophobic interaction chromatography (HPHIC) packing material with a special function. Amphiprotic functional molecule cholesterol on a cell membrane is taken as a stationary phase aglucon, and surface chemical modification is performed on silica matrix, thus obtaining the biomimetic HPHIC packing material. An HPHIC column filled with the packing material adopts salt-water as an elution system, and can be applied to natural protein separation and renaturation and simultaneous purification of denatured lysozyme, a recombined human Flt3 ligand (rhFL) inclusion body and a recombined human stem cell factor (rhSCF).

The invention discloses a high-elasticity putty paste which belongs to the technical field of building coating. The high-elasticity putty paste comprises the following components in parts by weight: 40-60 parts of construction emulsion or elastic emulsion, 0.5-1.5 parts of film-forming auxiliary agent, 0.1-0.3 part of dispersing agent, 0.1-0.3 part of mildewproof agent, 40-60 parts of bentonite, 20-30 parts of stuffing, 3-7 parts of garbage cotton and 40-60 parts of water. Because the dispersing agent is added into the prescription of the high-elasticity putty paste, mutual aggregation among insoluble particles is avoided, and the stable emulsion is formed after stirring the components with water, therefore, the stability of the putty paste is improved; since the garbage cotton is also added to the prescription and uniformly stirred into the putty paste, the elasticity and the tensile capacity of the putty paste are both improved so that the putty paste has the effect of cracking and water prevention.

The invention discloses a method for assisting the in vitro renaturation of lysozyme by using granular poly (N-isopropylacrylamide-sodium acrylate) copolymer gel, the specific steps are as follows: 1) the granular poly (N-isopropylacrylamide-sodium acrylate) copolymer gel is prepared by using the inverse suspension copolymerization; 2) the granular poly (N-isopropylacrylamide-sodium acrylate) copolymer gel is used for assisting the in vitro renaturation of the lysozyme. The granular poly (N-isopropylacrylamide-sodium acrylate) copolymer gel which is developed by the method is taken as a novel protein in vitro renaturation additive, thereby having the following advantages: (1) the activity recovery rate of a target protein can be significantly improved under the condition of high denatured protein concentration; (2) the separation and the recovery are convenient by utilizing the thermosensitive characteristic of the gel after the completion of the renaturation, and the gel can be repeatedly utilized; (3) the hydrophobic performance of the gel can be regulated by controlling the content of the co-monomer sodium acrylate, thereby changing the low critical dissolution temperature and the largest swelling ratio and being applicable to the different target proteins. Therefore, the gel has better application prospect in the field of the protein renaturation.

The invention discloses a supporting body for a microwave magnetron and relates to the technical field of metallized ceramic processing. The supporting body includes an annular ceramic matrix and a metallized layer, and is prepared from silicon carbide-triazole silane-aluminum nitride mesh matrix, blast furnace slag, strontium titanate, a dispersing agent, a defoaming agent and other raw materialsthrough the steps of silicon carbide-triazole silane-aluminum nitride mesh laminated matrix preparation, mixing, granulation, sintering and the like. Raw materials of the metallization layer comprisetitanium powder, aluminum powder, copper powder, clay and a binder. The invention further discloses a preparation method of the support body composed of the metallization layer and the annular ceramic matrix. The insulating ring for the microwave magnetron has high density and tensile strength, has excellent tensile strength, toughness, high temperature resistance and thermal conductivity, can reduce the cost of raw materials, and achieves the purposes of energy conservation and environmental protection.

The invention discloses a moderate-intensity electric field based treatment method for reducing oil absorption amount of fried food. The method comprises the following steps: oil is heated, materials are added for frying treatment, and moderate-intensity electric field treatment is applied in the frying treatment process, wherein the voltage range of the electric field treatment is 5-100 V, and the frequency range of the electric field treatment is 1-100 KHz; and the frying treatment temperature is 120-200 DEG C. According to the moderate-intensity electric field treatment based method for reducing the oil absorption amount of the fried food, the uniform and strong moderate-intensity electric field is formed after parallel polar plates in a frying pan are powered on, and after the materials are put into the frying pan to be fried, an electric field can affect bubbles generated by the materials and prevent the bubbles from being mutually gathered, so that the heat transfer efficiency is improved, the frying time is shortened, and splashing of oil droplets is reduced; and meanwhile, rapid heat transfer also accelerates rapid formation of hardened shells on the surfaces of the materials, evaporation of internal water is further inhibited, and the oil absorption amount is reduced.

The invention discloses an expandable polystyrene fireproof plate, and relates to the field of preparation of expandable polystyrene. The expandable polystyrene fireproof plate comprises the following raw materials in part by weight: 46-61 parts of internally used flame retardant, 64-98 parts of externally used flame retardant and 10 parts of cured expandable polystyrene particles, and is characterized in that the internally used flame retardant comprises the following ingredients in part by weight: 10-11 parts of ammonium phosphate, 0.8-1 part of antimonous oxide, 4-5 parts of aluminum chloride, 1-2 parts of zinc borate, 8-9 parts of magnesium chloride, 12-13 parts of citric acid and 15-21 parts of deionized water; and the externally used flame retardant comprises the following ingredients in part by weight: 20-25 parts of micro-encapsulation red phosphorus, 10-15 parts of aluminum hydroxide, 6-8 parts of expansible graphite, 10-15 parts of magnesium hydrate and 0.5-1 part of auxiliaries. By the scheme, the fireproof performance of the expandable polystyrene is fulfilled, and the original low heat conduction and the original high waterproofness of the expandable polystyrene are maintained.

The invention discloses an F3 polypeptide targeted nano organic metal frame material (nMOFs) and a preparation method thereof. A transition element Zr and an organic ligand BDC-N3 are synthesized intoa nano-carrier UIO-66-N3, and then two PEGs of which the tail ends are modified by alkynyl are loaded on the surface of the UIO-66-N3 through a click chemical reaction, thereby avoiding the aggregation between nanoparticles, and increasing the long circulation effect of the nanoparticles; then an F3 polypeptide is conjugated on the surface of the UIO-66-N3 to give the UIO-66-N3 targeting. In thewhole chemical transformation process, the structure of a framework of the UIO-66-N3 is retained and loaded with DOX to prepare a fluorescent imaging agent for treatment, and the nanoparticles of thesynthesized DOX/UIO-66-PEG-F3 have the effects of treatment and targeting. The F3 polypeptide targeted nano organic metal frame material (nMOFs) has potential clinical application value, and providesmore powerful technical support for the treatment of malignant tumors.

The present invention discloses black sesame seed plant protein drink. The drink comprises the following raw materials in weight percentages: 2.5%-5% of black sesame seeds, 0.5%-2% of peanuts, 0.5%-2%of puffed rice flour, 0.2%-0.5% of a stabilizer, 0.2%-0.5% of an emulsifier, 0.11%-0.1% of phosphate and 0.01%-0.2% of edible essence. The black sesame seed plant protein drink preserves all the nutrients of the black sesame seeds in the raw materials and is also good in stability in shelf life, free of precipitation and gelling phenomena, also delicate in mouthfeel and good in uniformity. The present invention also discloses a preparation method of the black sesame seed plant protein drink.

The invention discloses a magnesium-doped calcium silicate crystal nucleus early strength agent with long-term stability and a preparation method of the magnesium-doped calcium silicate crystal nucleus early strength agent. The magnesium-doped calcium silicate crystal nucleus early strength agent is prepared from the following components in parts by mass: 0.1-5 parts of acid liquor; 1-20 parts of a dispersant; 0.2 to 5 parts of soluble magnesium salt; 3 to 30 parts of soluble calcium salt; and 3-30 parts of soluble silicate. Magnesium ions easily enter the structure of the silicate polymer and react to generate a hydrated magnesium silicate gel network, and the gel network increases steric hindrance and can prevent mutual aggregation of crystal nucleus particles, so that the effect of stabilizing the crystal nucleus particles is achieved, and the crystal nucleus suspension is kept stable for a long time. Meanwhile, after magnesium ions are doped, unreacted dispersing agent molecules can be complexed, so that the reaction rate of the dispersing agent is increased, the specific surface area of the nanocrystal nucleus is also increased, the cement hydration promoting effect of the nanocrystal nucleus is improved, and the early strength of cement is improved.

The invention relates to the technical field of anticorrosive materials, and discloses a high-performance solvent-free epoxy heavy-duty anticorrosive material, which is prepared from the following components in percentage by mass: 20 to 30 percent of polyester resin, 5 to 10 percent of epoxy resin, 10 to 15 percent of polyamide, 2 to 5 percent of calcium carbonate, 4 to 7 percent of dispersing agent, 0.5 to 2 percent of coupling agent and filler, and is good in dispersion property and capable of preventing mutual aggregation of filler particles; proper compatibility with resin and filler is realized; the thermal stability is good; the flowability is good during forming processing; color drift is not caused; according to the present invention, the product performance is not affected, the viscosity of the synthetic resin melt can be reduced during the processing process, and the dispersity of the filler can be improved so as to improve the processing performance, such that the product has good surface quality and good mechanical, thermal and electrical properties. The material has the characteristics of low viscosity, good mechanical property, excellent chemical property and the like, and the properties such as heat resistance, water (moisture) resistance, insulation and the like, especially the processing (operation) and mechanical properties, are remarkably improved.