The invention discloses a snakegourd fruit vegetable protein beverage and a preparation method thereof, wherein the snakegourd fruit vegetable protein beverage comprises components with parts by weight: snakegourd fruit seed kernel meal 30-40 parts, citrus 3-5 parts, honeysuckles 4-5 parts, chrysanthemums 3-6 parts, acidulants 1-2 parts, flavouring agents 2-3 parts, vitamin C 6-10 parts, grape juice 10-12 parts, sweetening agents 2-4 parts, emulgator 1-1.5 parts, stabilizers 2-3 parts and water 60-80 parts. The method for preparing the snakegourd fruit vegetable protein beverage comprises steps: pretreatment of raw materials, defibrination, melting and mixing materials, constant volume, double homogeneous treatment, heating, filling, sterilization, concentration and packaging. Compared with the prior art, the snakegourd fruit vegetable protein beverage and the preparation method thereof have the beneficial effects that the snakegourd fruit vegetable protein beverage is high in protein content, low in fat content, high in nutritive value and better in taste, has obvious anti-hyperlipid and anti-thrombus effects, resists acute myocardial ischemia, reduces blood, enhances human immunity, delays senescence, soothes the nerves and nourishes and the like, is complete in care functions, and has the effects of discharging toxification and lubricating the intestines, beautifying the features and keeping fit.