791 results about "Acide succinique" patented technology

The invention discloses a pharmaceutical composition containing melogabalin besylate and a preparation method of the pharmaceutical composition. Belongs to the technical field of pharmaceutical preparations. Comprising melogabalin besylate and pharmaceutically acceptable auxiliary materials, the pharmaceutically acceptable auxiliary materials comprise a filler, a disintegrating agent, an adhesive, an antioxidant and a lubricant, the antioxidant comprises vitamin E succinic acid polyethylene glycol ester, and the lubricant comprises vitamin E succinic acid polyethylene glycol ester. The melogabalin besylate as the active ingredient accounts for 2-15% by weight of the pharmaceutical composition, preferably 2-10% by weight of the pharmaceutical composition. According to the pharmaceutical composition, antioxidant particles are prepared by adopting a fluidized bed granulation process, raw material medicines, the antioxidant particles and other auxiliary materials are mixed, tableted and coated, an antioxidant comprises vitamin E succinic acid polyethylene glycol ester and tartaric acid, and the prepared tablet has good stability.

The invention discloses a green phosphorus-free and nitrogen-free corrosion and scale inhibitor, and relates to the technical field of energy-saving and environment-friendly water treatment agents. The corrosion and scale inhibitor is prepared from polyaspartic acid, hydrolytic polymaleic acid, acrylic acid / hydroxypropyl acrylate copolymer, polyepoxysuccinic acid, delta-valerolactam, sodium borate, zinc sulfate heptahydrate and benzotriazole according to a specific proportion. The preparation method comprises the following steps: preparing the modified polyaspartic acid, adding other components, mixing the modified polyaspartic acid and other components, adjusting the pH value, homogenizing, filtering, filling and the like. The corrosion and scale inhibitor has excellent corrosion and scale inhibition performance, the corrosion inhibition efficiency of the corrosion and scale inhibitor reaches up to 88.6%, and the scale inhibition rate ranges from 90.5% to 92.4%. Compared with a contrast agent, the efficient corrosion and scale inhibition performance is provided, meanwhile, the water treatment agent has the advantages of being environmentally friendly, economical and the like, and is a green water treatment agent with great application prospects.

The invention relates to a phosphorus-free zinc-free seawater special-purpose scale and corrosion inhibitor, which comprises, by weight, 20-25% of sulfonic acid modified polyaspartic acid, 8-12% of quaternized chitosan, 5-10% of a sulfonate copolymer, 5-10% of polyepoxysuccinic acid, 1-3% of benzotriazole or methyl benzotriazole, 0.5-1% of sodium tungstate, and the balance of deionized water. According to the formula, traditional corrosion inhibitors such as phosphorus and zinc are completely abandoned, functions are achieved through natural polymer derivatives such as sulfonic acid modified polyaspartic acid and quaternized chitosan, and the scale and corrosion inhibitor has the following environmental protection advantages that the scale and corrosion inhibitor does not contain phosphorus and zinc elements at all, and water eutrophication and heavy metal accumulation caused by a traditional phosphorus and zinc formula are avoided.

The invention relates to a crystal type mild cleansing cream and a preparation method thereof, and belongs to the technical field of cosmetics. The crystalline mild cleansing cream is prepared from the following components: glycerol, a mixed amino acid surfactant, lauryl hydroxyl sulfobetaine, disodium lauryl sulfosuccinate, a chelating agent, citric acid, a preservative, a skin conditioning component and water, wherein the mixed amino acid surfactant is formed by mixing solid potassium cocoyl glycinate, solid sodium cocoyl glycinate and a sodium cocoyl glycinate aqueous solution; the cleansing cream comprises the following components in percentage by mass: 25%-35% of glycerol, 18%-25% of active ingredients of the mixed amino acid surfactant, 3%-4.5% of lauryl hydroxyl sulfobetaine and 1%-3% of disodium lauryl sulfosuccinate. According to the crystal type mild cleansing cream, no extra thickening agent component is used, the cream body which is good in texture and stable is obtained only through synergistic thickening of the three amino acid surfactants, irritation is small, sensitive skin friendliness is achieved, the preparation technology is simple, and cost is low.

The invention relates to the technical field of scale and corrosion inhibitors, in particular to a preparation method and application of an enhanced boric acid efficient environment-friendly phosphorus-free scale and corrosion inhibitor, and the enhanced boric acid efficient environment-friendly phosphorus-free scale and corrosion inhibitor comprises the following components in parts by weight: 50-100 parts of a water-soluble polyol-boric acid mixture, 0-50 parts of polyepoxysuccinic acid, 0-50 parts of polyaspartic acid, 0-50 parts of benzotriazole and 0-50 parts of zinc chloride. The high intermiscibility of polyhydric alcohol, water and boric acid is utilized, the dosage of boric acid in a solution is effectively increased, the effects of boric acid on scale inhibition, corrosion inhibition, sterilization and the like are amplified, meanwhile, the freezing temperature of the scale and corrosion inhibitor is reduced due to the addition of polyhydric alcohol, the scale and corrosion inhibitor can be used in winter more easily, and the scale and corrosion inhibitor is suitable for popularization and application. The invention provides an implementation way of a novel efficient environment-friendly phosphorus-free scale and corrosion inhibitor, and the scale and corrosion inhibitor has the advantages of environment friendliness, convenience in use and good scale and corrosion inhibition performance.

The invention belongs to the technical field of anticorrosive coatings, and particularly relates to a high-temperature-resistant hydrophobic anticorrosive coating as well as a preparation method and application thereof. The invention provides a high-temperature-resistant hydrophobic anticorrosive coating, which is prepared from the following raw material components in parts by weight: 100 to 140 parts of epoxy resin; 3 to 7 parts of 2-benzothiazole thiosuccinic acid; 2 to 6 parts of hydrophobically modified ZIF-67 (at) MgAlCeFe-LDH (layered double hydroxide); 4-8 parts of a filler; 2-6 parts of a dispersant; 1-3 parts of a defoaming agent; 2-4 parts of a coalescing agent; 15-35 parts of a curing agent; 20 to 30 parts of water; and 10 to 20 parts of ethanol. The hydrophobic property of the coating can be improved by adding hydrophobic modified ZIF-67 (at) MgAlCeFe-LDH, and the corrosion resistance of the anticorrosive coating is remarkably improved by matching with 2-benzothiazole thiosuccinic acid and utilizing the interaction between the ZIF-67 (at) MgAlCeFe-LDH and the 2-benzothiazole thiosuccinic acid. The anti-corrosion coating prepared by the method has excellent corrosion resistance, hydrophobic performance and high temperature resistance.

The doxylamine succinate pyridoxine enteric-coated tablet comprises a tablet core and a coating layer, the coating layer comprises a first isolation layer, an enteric-coated layer and a second isolation layer, the materials of the enteric-coated layer comprise a plasticizer, an anti-sticking agent, a defoaming agent and a flexible coating material, and the flexible coating material accounts for 24-28% of the mass of the tablet core. By adding the flexible coating material, the stability of the pharmaceutical preparation is improved, the difference between batches is reduced, the drug dissolution rate reaches 90% or above, and the pharmaceutical preparation can be quickly released.

The invention belongs to the technical field of microorganisms, and particularly relates to saccharomyces cerevisiae, a fungicide, application and a screening method. The invention provides a saccharomyces cerevisiae strain DXMC847, which is classified and named as saccharomyces cerevisiae, and is preserved in China Center for Type Culture Collection on November 18, 2024, the preservation address is Wuhan University, Wuhan, China, and the preservation number is CCTCC NO: M 20242592. The saccharomyces cerevisiae strain BY4741 is used as an original strain, and a method of combining ultraviolet mutagenesis with flow sorting is utilized to realize high-throughput screening of acid-resistant strains, so that the acid-resistant strains can be efficiently screened, and the yield of the acid-resistant strains is improved. And finally obtaining the acid-resistant saccharomyces cerevisiae DXMC847. The result of the embodiment shows that the content of pyruvic acid, L-malic acid and succinic acid in the fermentation liquor of the saccharomyces cerevisiae DXMC847 is obviously improved compared with that of the saccharomyces cerevisiae BY4741.

The invention relates to the technical field of glass cleaning agents, in particular to an environment-friendly cover plate glass cleaning agent and a preparation method thereof. The environment-friendly cover plate glass cleaning agent comprises the following raw materials in percentage by weight: 12-20% of inorganic base, 8-12% of a surfactant, 5-8% of a chelating agent, 3-5% of a humectant, 1-3% of an adsorbent, 1-3% of a dispersing agent, 0.3-1% of a buffering agent and the balance of deionized water, the surfactant is dodecyl glucoside and dodecyl ethyoxyl sulphobetaine, and the weight range ratio of the dodecyl glucoside to the dodecyl ethyoxyl sulphobetaine is (3-1): 1; the chelating agent is one or more of sodium gluconate, sodium polyaspartate and sodium polyepoxysuccinate. According to the present invention, the degradable surfactant and the degradable chelating agent are adopted, and the dispersant is added to modify the nanometer titanium dioxide, such that the low pollution property is achieved while the high decontamination efficiency and the anti-fingerprint ability are considered.

The invention belongs to the technical field of composite gel and application thereof, and relates to colon-targeted composite gel and a preparation method and application thereof.The preparation method of the colon-targeted composite gel comprises the following steps that S1, polysaccharide and protein are dissolved in water with the same volume, and a polysaccharide solution and a protein solution are correspondingly obtained; s2, mixing the protein solution and the polysaccharide solution, adding succinic acid and calcium chloride, and finally staying overnight at 4 DEG C to obtain the colon-targeted composite gel. Polysaccharide, protein, succinic acid and calcium chloride are adopted to form the colon-targeted composite gel, the colon-targeted composite gel has a compact and stable structure, the encapsulation efficiency of succinic acid is greatly improved, the targeted release rate of succinic acid in colon is facilitated, and precise targeted delivery of succinic acid in colon is realized.

The invention relates to the technical field of membrane separation treatment, in particular to a composite separation membrane and a preparation method and application thereof. The composite separation membrane comprises a hollow polymer base membrane and a modified layer attached to the outer surface of the hollow polymer base membrane, wherein the surface of the hollow polymer base membrane is provided with a plurality of membrane holes, and at least part of the modified layer forms recesses in the membrane holes; the modified layer comprises graphene oxide nanosheets, nanocellulose and sulfonated succinic acid; at least part of the nanocellulose is fixed between sheet layers of the graphene oxide nanosheets, and at least part of the sulfonated succinic acid is fixed between sheet layers of the graphene oxide nanosheets; the modified layer and the hollow polymer base membrane in the composite separation membrane have good bonding strength, and the composite separation membrane has the advantage of good stability, has good hydrophilicity and can effectively improve the separation efficiency.

The invention belongs to the technical field of bone repair hydrogel, and discloses a hydrogel band-aid for bone repair and a preparation method and application thereof, and the preparation method comprises the following steps: mixing a polyethylene glycol succinimide succinate solution with an alendronate solution, dialyzing, and freeze-drying to obtain alendronate modified polyethylene glycol succinimide succinate; and uniformly mixing alendronate modified polyethylene glycol succinimide succinate, polyphenol, metal ions and water in proportion, carrying out solid-liquid separation, and drying the solid to obtain the hydrogel. The preparation process provided by the invention has the advantages of simplicity, convenience and rapidness, not only simplifies the production process, but also enhances the bone regeneration, angiogenesis and immunoregulation capabilities.

The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to a melogabalin besylate tablet containing a stabilizer and a preparation method of the melogabalin besylate tablet. The melogaba besylate tablet containing the stabilizer comprises a coating and a tablet core, wherein the tablet core comprises the following components: melogaba besylate, the stabilizer, a disintegrating agent, a lubricating agent and the balance of a filling agent; and the coating is prepared from the following materials: an Intai W100 film coating premixing agent and acrylic resin IV. The filling agent comprises xylitol, pregelatinized starch and maltodextrin in a mass ratio of (3-4): 3: (1-2). The stabilizer is vitamin E succinic acid polyethylene glycol ester. The coating is prepared from the following materials: an Intai W100 film coating premixing agent and acrylic resin IV in a mass ratio of (1-1): (1-2). According to the melogabalin besylate tablet prepared by the invention, the stability and the dissolution performance can be synchronously improved.

Methods employing detergent compositions effective for reducing hard water scale and accumulation on hard surfaces, namely within food, beverage and pharmaceutical applications are disclosed. The detergent compositions employ phosphinosuccinic acid adducts in combination with an alkalinity source and optionally polymers, surfactants and / or oxidizers, providing alkaline compositions having a pH between about 10 and 13.5.

The invention discloses an anti-fatigue detection method for a structural member made of a high polymer material, and belongs to the field of material detection.The anti-fatigue detection method comprises the following steps that S1, a thermoplastic high polymer raw material for preparing the structural member is heated to be in a molten state, and a first intermediate is formed; s2, preparing a shell layer by taking polylactic acid, Y-type polyethylene glycol succinic acid, acetylsalicylic acid and a DCP catalyst as raw materials, and preparing fluorescent color developing agent microspheres by taking a high-temperature-resistant liquid fluorescent color developing agent as a core material; s3, adding fluorescent color developing agent microspheres into the first intermediate, uniformly stirring, heating, continuously stirring, uniformly mixing the color developing agent with the first intermediate after the color developing agent is released to obtain a second intermediate, and performing injection molding, molding, curing and cooling on the second intermediate to obtain a structural part sample; and S4, carrying out fatigue detection on the structural member sample by adopting a fatigue testing machine. The method solves the problems that closed cracks or internal defects are difficult to directly recognize from the inside and the initiation and expansion process of the internal cracks of the component cannot be captured at present.

The present invention relates to a dispersant for graphite and graphene and its application. The composition is a synergistic combination of alkyl sulfosuccinate and polyalkylene glycol. Appropriate adding amount thereof can quickly and easily disperse graphite and graphene in the medium, improve its dispersion uniformity and stability, delay its sedimentation, and inhibit its re-accumulation. Furthermore, the present invention can apply graphite and graphene to other media besides non-water-based or organic solvents. The composition of the present invention does not contain flammable volatile chemicals, any fluorine-, silicon- or phosphorus-based compounds, or any aromatic substances. The present invention can not only reduce environmental pollution but also improve the operational safety of relevant personnel.

The invention relates to a method for preparing lithium sulfide through a high-temperature solid-phase reaction. Weighing lithium carbonate and powdered sulfur, and putting the lithium carbonate and the powdered sulfur into an agate mortar for grinding; transferring the ground mixture into a high-temperature-resistant ceramic crucible, and putting the ceramic crucible into a vacuum tube furnace for presintering; after the presintering is finished, carrying out high-temperature reaction; after the reaction is finished, turning off a heating power supply of the vacuum tube furnace, and naturally cooling the crucible to room temperature in the furnace; after cooling is completed, opening a furnace door, and taking out the crucible to obtain a lithium sulfide crude product; putting the lithium sulfide crude product and the wear-resistant dispersing agent into the mortar, and grinding and crushing again; then screening by a standard screen to obtain lithium sulfide powder products with different particle sizes; the wear-resistant dispersing agent is prepared by reacting dioctadecylamine, an epoxy succinic acid polymer and ethidene diamine; the lithium sulfide prepared by the method disclosed by the invention has relatively high purity and yield.

The invention discloses a PSA electrotinning insoluble anode system and a production method of an electrotinning plate, and relates to the technical field of electrotinning. The PSA tin electroplating insoluble anode system comprises an electroplating additive which is composed of benzotriazole, N-oleoyl sarcosine, S-carboxyethyl thiosuccinic acid and sodium citrate. The problems of serious black ash and poor coating performance of an electroplated tin plate product are solved, the tin plating stability of a plating solution in an electroplating bath is improved, the black ash on the surface of the electroplated tin plate product can be effectively reduced, the requirements of low black ash and high adhesive force on the surface of an electroplated tin plate of a PSA (Pressure Swing Adsorption) electroplated tin insoluble anode system are met, and the service life of the electroplated tin plate is prolonged. The electroplated tin plate produced through the PSA electroplated tin insoluble anode system is bright and clean in plating layer surface, and after the tin layer surface with the thickness of 8.4 g / m < 2 > and below is wiped through test paper, the reduction percentage of the test paper whiteness caused by black ash is smaller than or equal to 10%.

A diesel fuel composition including (a) a quaternary ammonium salt additive; and (b) one or more nitrogen-free detergents; wherein the quaternary ammonium salt additive includes the quaternised reaction product of a hydrocarbyl substituted succinic acid derived acylating agent and a compound able to react with said acylating agent and which includes a tertiary amine group; wherein each molecule of the hydrocarbyl substituted succinic acid derived acylating agent includes on average at least 1.2 succinic acid moieties.

The invention provides self-adhesive modified asphalt, a self-adhesive modified asphalt waterproof coiled material and a preparation method of the self-adhesive modified asphalt waterproof coiled material, and belongs to the technical field of asphalt and waterproof coiled materials. The self-adhesive modified asphalt is prepared from the following components in percentage by weight: 3 to 30 weight percent of matrix asphalt, 20 to 30 weight percent of aromatic hydrocarbon oil, 3 to 5 weight percent of thermoplastic elastomer, 5 to 8 weight percent of rubber modifier, 5 to 10 weight percent of tackifying resin, 3 to 8 weight percent of dioctyl sodium sulfosuccinate, 1 to 3 weight percent of polyaluminum ferric chloride, 1 to 3 weight percent of ferroferric oxide and 0.5 to 1 weight percent of limestone powder, and 10 to 30 wt% of an inorganic filler.

The invention discloses a method for constructing an atrial fibrillation small animal model through succinic acid induction and application, and the method comprises the following steps: in an animal model construction period, enabling a small animal to ingest an aqueous solution containing succinic acid or all pharmaceutically acceptable salts of succinic acid every day, and finishing the modeling period to obtain the animal model. Compared with a traditional angiotensin AngII administration method, the atrial fibrillation small animal model has the advantages that the cost of a medicine for constructing the animal model is lower, the economic benefit is higher, and the atrial fibrillation induction effect is better; the model represents the most common atrial fibrillation type in clinic, and compared with an acute transient atrial fibrillation model, the research and application range is wider; compared with tail vein injection, intraperitoneal injection, subcutaneous pump burying and other modes, the non-creative model has the advantages that damage to small animals is smaller, and the requirement for the operation technology is low.

Provided is a catalyst for polymerization of an olefin, capable of easily producing a propylene homopolymer with an excellent melt flow rate and moldability, as well as further excellent flexural modulus, despite containing a solid catalyst component for polymerization of an olefin comprising a compound other than phthalate esters as an internal electron-donating compound. A catalyst for polymerization of an olefin, comprising: a solid catalyst component for polymerization of an olefin, comprising magnesium, titanium, halogen, and a succinic acid diester compound, wherein a ratio (S / T), represented by a total content of an internal electron-donating compound with the succinic acid diester compound as a main component (S) to a content of the titanium (T), is 0.60 to 1.30 in a molar ratio, an organoaluminum compound, and one or more external electron-donating compounds selected from specific aminosilane compounds.

The polyester resin is described, which has repeating units derived from a diester component of a dicarboxylic acid; and a diol component. The diester of the aliphatic dicarboxylic acid includes a succinic acid diester, the diol component comprises 50 to 100 mol % of an anhydrosugar alcohol, based on 100 mol % of the total diol component, and the number average molecular weight (Mn) of the polyester resin is 10,000 g / mol or more. A method for preparing a polyester resin comprises (1) esterification or transesterification of a diester component of a dicarboxylic acid comprising a diester of an aliphatic dicarboxylic acid and a diester of an aromatic dicarboxylic acid and a diol component comprising an anhydrosugar alcohol; and (2) polycondensation of the reaction product obtained in step (1). The polyester resin has excellent heat resistance and mechanical properties and also has excellent biodegradability.

The invention provides a PVA-free laundry sheet and a preparation method thereof, and relates to the technical field of detergents. The laundry sheet disclosed by the invention is prepared from the following raw materials in parts by weight: 5 to 15 parts of cellulose, 10 to 30 parts of sodium dodecyl sulfate, 5 to 20 parts of sodium alpha-olefin sulfonate, 5 to 20 parts of sodium dioctyl sulfosuccinate, 5 to 10 parts of cocamidopropyl betaine, 2 to 10 parts of glycerol and 0.1 to 2 parts of chelating agent, the viscosity of the cellulose ranges from 100 mpa * s to 1000 mpa * s. Cellulose with specific viscosity is used as an adhesive and is mixed with a surfactant with specific components, and the prepared laundry sheet is good in forming effect, easy to demould and dry, high in breaking strength and excellent in washing effect.

The invention discloses a non-phosphorus reverse osmosis scale inhibitor and a preparation method thereof, and relates to the technical field of industrial water treatment.The non-phosphorus reverse osmosis scale inhibitor is prepared from, by weight, 10 parts of purified humic acid, 40-60 parts of alkalized acrylic acid-succinimide-hydroxypropyl methacrylate copolymer, 4-8 parts of sodium polyepoxysuccinate and 5-20 parts of water. Compared with the prior art, the scale inhibitor is high in environment-friendly compliance, excellent in scale inhibition performance, scientific and efficient in raw material treatment and high in product scale inhibition rate, meets the environment-friendly emission standard, and is suitable for reverse osmosis membrane scale inhibition treatment in the industries of electric power, chemical engineering, seawater desalination and the like.

The invention relates to the technical field of surfactants, and particularly discloses a preparation method and application of a sulfosuccinate type surfactant, and the preparation method specifically comprises the following steps: (1) esterification reaction: under the protection of inert gas, adding fatty alcohol and carboxylic acid anhydride, introducing gas for 10-20 minutes, adding a difunctional acidic site catalyst, heating to 95-105 DEG C, and reacting for 2-3 hours to obtain an esterification product; and (2) sulfonation reaction: cooling the esterification product to 70-80 DEG C, dropwise adding 20-40wt% of sulfonating agent aqueous solution, preserving heat for 1-2 hours after dropwise adding, and then performing post-treatment to obtain the sulfosuccinate type surfactant. In the preparation process, one-pot preparation is realized by regulating and controlling process conditions and developing a catalyst to efficiently catalyze esterification and sulfonation, intermediate products do not need to be separated between esterification and sulfonation, material loss caused by transfer and separation is avoided, the adopted catalyst can be used for inhibiting premature oxidation of a sulfur source in the sulfonation process, and the sulfonation efficiency is improved. The generation of byproducts is reduced, and the yield is improved.

The present invention discloses a combined flotation regulator for high-mud lead-zinc oxide ores and its application method. The combined regulator consists of regulator A and regulator B in a mass ratio of 1:(3-10); regulator A is a high-molecular polysaccharide substance; regulator B consists of B1 and B2, with B1 being 80-90 parts by mass and B2 being 10-20 parts by mass; B1 is sodium silicate, and B2 is at least one of polyaminopolyether methylene phosphonic acid, polyepoxysuccinic acid, and 2-butanephosphonate-1,2,4-tricarboxylic acid. The application method is as follows: grinding the raw ore, sequentially adding sodium carbonate, regulator A, regulator B, and sodium sulfide for slurry mixing, and finally adding a collector for zinc oxide mineral flotation to obtain a zinc oxide coarse concentrate. The present invention can effectively recover zinc oxide minerals in high-mud lead-zinc oxide ores, the reagent components are non-toxic and harmless, the application method is simple, and it is convenient for large-scale production management.

The invention relates to a cyclic utilization method of a maleic anhydride epoxidation catalyst. The method comprises the following steps: completely introducing a synthesized epoxy succinic acid reaction solution into an anion exchange column, adsorbing anions of a catalyst by using anion exchange resin, leaching the anion exchange column by using pure water, applying leacheate and the adsorbed reaction solution to synthesis of polyepoxysuccinic acid, adding quantitative maleic anhydride and water into a reaction kettle, and reacting for 2-4 hours at the temperature of 60-80 DEG C; and dropwise adding liquid alkali for hydrolysis, adding anion resin adsorbing the catalyst, heating, dropwise adding an aqueous hydrogen peroxide solution, then carrying out suction filtration, separating the anion resin from the epoxy succinic acid reaction solution, and continuously using the obtained anion resin and epoxy succinic acid reaction solution according to the steps to complete the recycling of the catalyst. According to the method, the specific anion resin is used for adsorbing the catalyst in the reaction system, and the catalyst and the adsorption resin can be recycled for multiple times only by adding the resin adsorbing the tungsten and molybdenum catalysts into the reaction system.

Provided is a biodegradable rubber composition which includes biodegradable materials instead of some rubber components to achieve high biodegradation efficiency. The biodegradable rubber composition includes a polyalkylene succinate adipate (PASA) resin, a peroxide crosslinking agent, and a rubber capable of being crosslinked by the peroxide crosslinking agent.

The invention discloses a picromerite collecting agent and application thereof. The collecting agent is one or a mixture of more of alcohol ether sulfosuccinic acid monoester disodium salt, lauryl sulfonated succinic acid monoester disodium salt and lauryl alcohol polyoxyethylene ether sulfosuccinic acid monoester disodium salt. The flotation collecting agent is mainly used for flotation separation of picromerite and can be selectively adsorbed on the surface of picromerite mineral, floatability difference between the picromerite mineral and impurity minerals such as sodium chloride is increased, floatability of the picromerite mineral is enhanced, and flotation efficiency is improved.