62results about How to "Experimental repeatability is strong" patented technology

The invention discloses a preparation method of calcium phosphate nanopowder with a controllable length-to-diameter ratio and calcium-to-phosphorus ratio. The method comprises the step: carrying out areaction by mixing phosphate or phosphoric acid with a calcium salt to prepare the calcium phosphate nanopowder, wherein the one-dimensional size of a calcium phosphate nanoparticle can be regulatedto be 50nm-5mu m and the length-to-diameter ratio can be regulated to be 2-50 by adding a pH regulator into a reactant, components and proportions of the calcium phosphate nanopowder serving as a product can be regulated by controlling the feeding ratio of the phosphate or phosphoric acid to the calcium salt to be 1.5-1.67, and the calcium phosphate nanopowder is beta-tricalcium phosphate and/or hydroxyapatite. According to the method disclosed by the invention, the length-to-diameter ratio of the product is regulated by controlling the proportion of weak bases and relatively strong bases in the pH regulator; the calcium-to-phosphorus ratio of the product is controlled by changing the feeding ratio of a calcium source to a phosphorus source; a supergravity technology is combined to enhancea micromixing effect, so that the calcium phosphate nanopowder is prepared; and the preparation method is low in production cost, simple in operation, good in repeatability, better in application performance and wider in application range.

The present invention discloses a nanometer hydroxyapatite dispersion body and a preparation process thereof. According to the nanometer hydroxyapatite dispersion body, nanometer hydroxyapatite particles are uniformly dispersed in a liquid phase medium, the solid content of the nanometer hydroxyapatite dispersion body is 1-5 wt%, the size of the nanometer hydroxyapatite particles is 40-60 nm, theaspect ratio of the nanometer hydroxyapatite particles is 1-5, and the liquid phase medium is water, an organic solvent, the mixture of a water-miscible organic solvent and water, or the mixture of different organic solvents. According to the present invention, by combining the hydrothermal method and the super gravity technology, the microcosmic mixing effect is strengthened, and the method has advantages of low production cost, simple operation and good repeatability; the prepared nanometer hydroxyapatite dispersion body has advantages of controlled particle size, good dispersion effect andgood stability; and with the technical scheme, the problems of easy agglomeration, poor dispersibility and the like of the nanometer hydroxyapatite particles can be solved, and the product can be endowed with the high application performance and the broad application range.

The invention relates to a method for preparing transparent aluminum hydroxide liquid dispersion. The method comprises the following steps: 1) dissolving an aluminum salt in water or in an organic solvent to prepare an aluminum salt solution and dissolving alkali in water or in another organic solvent so as to prepare alkali liquor; 2) adding the aluminum salt solution and the alkali liquor into a hypergravity rotation packed bed or sleeve type annular micro-channel reactor for precipitation and crystallization so as to prepare an aluminum hydroxide precursor suspension; 3) transferring the aluminum hydroxide precursor suspension into a hydro-thermal reaction vessel for water/solvent heat treatment; 4) subjecting slurry obtained after water/solvent heat treatment to standing, cooling, filtering and washing so as to obtain a filter cake; and 5) dispersing the cleaned filter cake in a liquid medium so as to obtain the transparent aluminum hydroxide liquid dispersion. The transparent aluminum hydroxide liquid dispersion prepared in the invention has good stability and has the characteristics of high ZETA potential, obvious Tyndall effect and thixotropic gelation.

The invention discloses a C21 steroid saponin aglycone derivative as well as a preparation method and an application thereof in preparing anti-tumor drugs. The structural formula of the C21 steroid saponin aglycone derivative is as shown in formula IX. The C21 steroid saponin aglycone derivative disclosed by the invention has the advantages of being better in bioactivity, higher in selectivity, lower in toxicity and the like. The C21 steroid saponin aglycone derivative has a significant inhibitory effect on human breast cancer cells, cervical cancer cells, lung cancer cells and liver cancer cells (as shown in Specification), wherein R1 is selected from H and F, R2 is selected from H and F, and R3 is selected from H and F.

The invention discloses a sapogenin derivative shown as a structural formula IX, a preparation method of the sapogenin derivative, and application thereof in preparation of antitumor drugs. The structural formula is as shown in the specification, wherein R1 is selected from H and CH3; R2 is selected from H and CH3; and n refers to 1 and 2. The sapogenin derivative disclosed by the invention has the advantages of high biological activity, high selectivity, low toxicity and the like and has obvious effects of inhibiting human breast cancer cells, cervical cancer cells, lung carcinoma cells and hepatoma carcinoma cells.

The invention relates to an indium aluminum zinc oxide thin film transistor based on a gate dielectric layer with high dielectric constant and a full room temperature preparation method thereof. The indium aluminum zinc oxide thin film transistor includes a P<+>-Si substrate, a Ta2O5 gate dielectric layer, double active layers, a source electrode and a drain electrode which are arranged in turn from bottom to top. The preparation method includes the following steps: (1) growing a Ta2O5 gate dielectric layer on a P<+>-Si substrate; (2) growing a first layer of IAZO film on the Ta2O5 gate dielectric layer; (3) growing a second layer of IAZO film on the first layer of IAZO film; and (4) growing a source electrode and a drain electrode on the second layer of IAZO film. An IAZO TFT with excellent performance is prepared in a room temperature environment by exploring and optimizing the sputtering preparation conditions of the Ta2O5 gate dielectric layer. The prepared IAZO TFT shows extremelyhigh electrical performance, and has a broad application prospect in flexible display and integrated circuits in the future.

The invention relates to an experimental device and method for measuring the efficiency of replacing crude oil with supercritical carbon dioxide in a tight oil core. The invention belongs to the technical field of oil-gas field development. The device comprises a constant-temperature box, an intermediate container containing crude oil and CO2, a rock core holder and a replacement intermediate container, saturated crude oil operation and CO2 pressurization and injection operation are conducted on a rock core through a displacement pump, the amount of crude oil replaced by CO2 under different pressures and different pressure drops is measured, and the CO2 utilization rate and the CO2 crude oil replacement efficiency are calculated. Compared with the prior art, according to the invention, themeasurement of the efficiency of replacing crude oil in a compact rock core with supercritical CO2 at high temperature and high pressure is realized; gas expansion errors caused by adopting a traditional rock core weighing method are reduced, the limitation that the traditional method can only measure the replacement efficiency from formation pressure to atmospheric pressure is broken through, and measurement of the crude oil replacement amount under different pressure drops and gas-oil separation and accurate metering in the pressure drop process are achieved. The device is low in construction cost, wide in application range, high in precision, high in experiment repeatability and easy to popularize.

The invention belongs to the technical field of biological medicine, and particularly discloses a preparing method of a chondriosome-targeted multilayer tumor deep-penetration sound sensitizer with sound responsiveness. The method comprises the following steps of 1, synthesizing an adipose membrane with IR780; 2, hydrating the adipose membrane obtained in step 1, adding PFP, and conducting sonic vibration and centrifugation under an ice bath to prepare the sound sensitizer IR780-NDs. The sound sensitizer prepared by means of the preparing method can deeply penetrate through tumors at multiplelayers, and is uniformly distributed in the tumors.

The invention provides a device and a method for simulating hydrate decomposition induced by invasion of drilling fluid into a reservoir. The device comprises a high-pressure reaction kettle (34), a high-low-temperature water bath temperature control system (102), a high-low-temperature constant-temperature air bath box (21), a drilling fluid pumping system (104), a gas control system (105), a back-pressure unloading system (106) and a data acquisition system (107), wherein the reaction kettle is arranged in the high-low-temperature constant-temperature air bath box, a reaction temperature ofthe reaction kettle and a gas temperature in the gas control system are respectively controlled by the high-low-temperature water bath temperature control system, and the drilling fluid pumping systemis connected to the reaction kettle through a pipeline, the back-pressure unloading system and the gas control system communicate with the interior of the reaction kettle through pipelines and air inlet/outlet holes (10) formed in the upper part of the reaction kettle, and the back-pressure unloading system is used for separately controlling the pressure balance of the reaction kettle, the gas control system and the outside.

The invention discloses a preparation method of a bioactive medical dressing. The method comprises the following steps of S1, taking raw material solutions for later use, and performing printing through a microfluidic 3D printing assembly; and S2, introducing contents into all channels in a multi-channel coaxial jet head, controlling the flow speed, setting parameters of a 3D printer, and using the 3D printer to control a micro-fluidic chip to print the three-dimensional diabetic foot ulcer functional medical dressing, wherein the raw material solutions comprise an alginate solution, a first high-molecular polymer solution, a bioactive component solution and a second high-molecular polymer solution. According to the method, the process is simple, subsequent treatment of the dressing is not needed, the production efficiency is high, the cost is low, the product is stable, the precision is high, and the experimental repeatability is high.

The invention discloses an intelligent floating-structure mooring and broken cable experiment simulation system. The intelligent floating-structure mooring and broken cable experiment simulation system comprises an experiment module, an intelligent broken cable device, a mooring cable and an intelligent control and monitoring system, wherein the intelligent broken cable device is fixedly arrangedat a position of a cable guide hole of the experiment model, one end of the mooring cable is fixedly arranged at the bottom of a pool, the other end of the mooring cable is connected to the intelligent broken cable device, the mooring cable is connected to the position of the cable guide hole of the experiment model by the intelligent broken cable device, the mooring cable and the experiment modelcan be disconnected by the intelligent broken cable device, the intelligent broken cable device is controlled to achieve broken cable control of the mooring cable by the intelligent control and monitoring system, and dynamic response monitoring of the experiment model and instantaneous tension monitoring of the mooring cable are achieved. Broken cable control of a floating mooring structure is simulated under an experiment condition, the instantaneous dynamic response of a floating body and the dynamic characteristic of the mooring cable can be accurately simulated when the mooring cable is broken, and the problem of broken cable instantaneous control and monitoring under the experiment condition is solved.