33results about How to "High response controllability" patented technology

The invention discloses a preparation method of shape memory polyurethane based on lactide and 1, 4-p-dioxanone. The preparation method comprises the following steps of: firstly carrying out vacuum melting reaction on the 1, 4-p-dioxanone, stannous octoate and small molecule diol to generate hydroxyl-terminated polybutadiene (1, 4-p-dioxanone), carrying out vacuum melting reaction on the hydroxyl-terminated polybutadiene and the lactide as well as the stannous octoate to prepare the hydroxyl-terminated polybutadiene (lactide-co-1, 4-p-dioxanone), then reacting the hydroxyl-terminated polybutadiene with diisocyanate as well as the stannous octoate in a benzene solvent to generate prepolymer, and then reacting the prepolymer with an isopropyl alcohol solution of chain extender small molecule diol or small molecule diamine to prepare shape memory polyurethane. The invention adopts a tow-step method to prepare hydroxyl-terminated polybutadiene (lactide-co-1, 4-p-dioxanone), takes the benzene solvent as a pre-polymerization reaction solvent, introduces isopropanol as a cosolvent in the chain extension reaction, and can enhance reaction controllability, reduce by-product production, enhance product yield and obtain high molecular weight chain-shaped shape memory polyurethane with excellent shape memory performance.

The invention provides a composite edible gel material capable of forming into a thermal irreversible gel by means of thermal melting. The composite edible gel material comprises the components in weight percent: 10-60% of microcapsule particles, 2%-20% of retarder and 30%-70% of alginate. The invention further provides a preparation method of the composite edible gel material capable of forming the thermal irreversible gel by means of thermal melting. The preparation method of the composite edible gel material comprises the step of mixing the microcapsule particles, the alginate with the phosphate according to a certain proportion. The composite edible gel material is added into the water to be heated up to the dissolving temperature of the microcapsule wall material, the packed gel agent is released out of the microcapsule particles, the packed gel agent is reacted with the alginate under the delayed coagulation of the phosphate to form the irreversible calcium alginate gel, and thecalcium alginate gel can not be melted only according to the heat change, so that the special flavor and the quality structure of the hot food can be kept; and the gel forming time can be controlled according to the practical situation in the specific production process, so that the requirement of the production operation can be met.

The invention discloses a new preparation method of O-methyl isourea methyl sulfate. The method includes the following steps that a certain amount of dimethyl sulphate is added in a 500-mL three-mouthreaction bottle, quantitative urea is added in batches, after reaction liquid is clear, a thermal insulation reaction is conducted for a certain time, and the product, namely O-methyl isourea methylsulfate, is obtained. Urea and dimethyl sulphate are adopted as raw materials for the reaction under the microwave effect to prepare O-methyl isourea methyl sulfate. The method has the advantages thatthe reaction can smoothly occur at the low temperature at which a conventional method is difficult to conduct, the reaction time is largely shortened, and the reaction efficiency and the product purity are improved; the temperature is controlled to be 45-70 DEG C, reduction of the reaction temperature not only can reduce the safety risk, but also can reduce side reactions in the production process, and the product yield is thus increased to 80%.

The invention provides a method for preparing a titanium nitride nano film on a substrate surface, a substrate with the film and application thereof, and belongs to the technical field of secondary electron emission suppression. The method comprises the following steps: transferring a substrate to a reaction chamber through a pre-vacuum chamber, and vacuuming the reaction chamber; introducing an inert gas into the reaction chamber, annealing the substrate; returning the annealed substrate to the pre-vacuum chamber, and using an ammonia gas plasma and a gaseous titanium source for a plurality of gas washing cycles of the reaction chamber; sending the substrate back to the reaction chamber, maintaining the temperature of the reaction chamber at 150 to 220 DEG C, and using the ammonia gas plasma and the gaseous titanium source for plasma enhanced titanium nitride atomic layer deposition reaction to obtain the substrate with the titanium nitride nano film. The ultrathin film prepared by the method has strong controllability, bonding strength between the film and the substrate is high, surface conformality is good, and surface uniformity in complex structures such as plane and porous structures is high.

The present invention discloses a synthesis process of a novel silicon paste with high defoaming performance, and particularly relates to the technical field of defoaming agents, the novel silicon paste comprises the following raw materials by weight: 350-400 parts of silicone oil, 150-200 parts of hydrogen-containing silicone oil (the hydrogen content is 0.18%), 100-150 parts of vinyl silicone oil (the vinyl content is 0.8%), 50-70 parts of MQ resin, 20-40 parts of white carbon black, 0.02-0.06 part of a chloroplatinic acid-isopropanol solution (0.3 wt%), and 20-30 parts of a post-treatment agent Cat.2. The methyl silicone oil is used as a reaction dispersing agent and a defoaming component by combining hydrosilylation reaction, and meanwhile, the MQ resin and the white carbon black are introduced as a reinforcing agent and a defoaming active component, so that on one hand, the white carbon black has the effect of reducing the reaction activity to enable the cross-linking reaction to be controllable, and on the other hand, the silicon paste process is combined, and the time of the silicon paste preparation process is greatly shortened; and the high-performance silicon paste with simple process and high efficiency is obtained.

The invention relates to a preparation method of a key intermediate ((3R,6S)-1-benzyl-6-methyl piperidine-3-amine) of a JAK3 enzyme inhibitor, and particularly relates to a method for preparing the required intermediate by taking 6-methyl piperidine-3-amine as an initial raw material through Boc protection, catalytic hydrogenation, benzyl protection, trifluoroacetic acid Boc de-protection, salt forming and splitting, and dissociation. The salt forming and splitting method comprises the following steps: mixing a racemic mixture containing a compound enantiomer with a structure shown in the formula with a splitting reagent with definite stereo-specificity in a solvent to form a solution, wherein the splitting agent is capable of binding at least one but not all of said enantiomers to form a precipitate containing the at least one the stereo-specific form of enantiomers; and collecting and purifying the precipitate , or collecting a solution containing other enantiomers and recrystallizing the enantiomers contained in the solution. The preparation method has the advantages of cheap and easily available raw materials, mild reaction conditions, high reaction controllability and good industrial application prospect.

The invention discloses a method for cross coupling of N-arylamine and cyclic ketoxime ester C (sp3)-C (sp3) through photooxidation reduction catalysis. According to the method, cyclic ketoxime ester is taken as a cyanogen alkylation reagent, C (sp3)-C (sp3) cross-coupling reaction of N-arylamine and cyclic ketoxime ester is realized under the condition of no metal catalysis, various N-arylamine and cyclic ketoxime ester are converted into corresponding target compounds at good to excellent yield under mild conditions, and the method has a wide reaction substrate application range. The synthesis strategy can be applied to structural modification of d-aminocarbonyl compounds and oligopeptide compounds. According to the present invention, the catalytic reaction condition is mild and simple, the catalytic reaction can be smoothly performed at the room temperature by using the 3CzClIPN as the catalyst, the reaction controllability is high, the cost is low, the high regioselectivity can be obtained without using the metal catalyst, the alkali and/or the other ligand, and the method is suitable for the large-scale production;

The invention provides a preparation method of a 6-nitro-4-substituted aminoquinazoline derivative. The method comprises the following steps: carrying out an amidation reaction on 2-halo-5-nitrobenzoate and 4-(thiazole-2-yl)methoxy-3-chloroaniline in the presence of a catalyst to obtain N-[4-(thiazol-2-yl)methoxy-3-chlorphenyl]-2-halo-5-nitrobenzamide, and carrying out substitution and condensation reactions on the N-[4-(thiazol-2-yl)methoxy-3-chlorphenyl]-2-halo-5-nitrobenzamide and a formamidine salt through a one-pot process in the presence of an acid-binding agent to obtain 6-nitro-4-[4-(thiazol-2-yl)methoxy-3-chlorphenyl]aminoquinazoline. The method has the advantages of cheap and easily available raw materials, good raw material stability, high reaction selectivity, easiness in operation of the reactions, and high yield and high purity of the product.