110 results about "Cordyceps scarabaeicola" patented technology

A bioactive substance for conditioning human constitution and regulating immunity is prepared from cordyceps through extracting, filtering, concentrating, evaporating, spray drying, high-speed centrifugal filtering or diatomite filtering, and loading in capsules or preparing wine or oral liquid.

The invention discloses a preparation method of high-purity plate-like cordycepin crystal. The method comprises the following steps: extracting cordycepin in a cordyceps militaris solid cultural medium residue, simultaneously enabling an extract to flow through macroporpous resin, and then carrying out recycling extraction and absorption on the cordyceps militaris solid cultural medium residue again; and eluting the cordycepin absorbed on the macroporpous resin, concentrating an eluent, crystallizing and recrystallizing to obtain the high-purity plate-like cordycepin crystal. The product obtained by the method has HPLC purity above 99.9% and is suitable for large-scale industrial production.

The invention discloses micro-ecological high-end pig feed ferment powder as well as a preparation method and an application method thereof and mainly relates to cultivation of a high-end pig by utilizing a micro-ecological technology. The micro-ecological high-end pig feed ferment powder is formed by fermentation of probiotics and comprises the following components: bacillus subtilis, bacillus licheniformis, enterococcus faecium, lactobacillus acidophilus, cordyceps sinensis and multiple pig intestinal probiotics as well as a health care nutrient solution prepared from Chinese herbal medicines. Probiotic powder/solution, corn flour, soybean meal, wheat bran, grass meal and the like are added with water and fermented to form a feed used for feeding pigs, and the health care nutrient solution is combined, so that feed-meat conversion rate can be (2.7-3.1):1; pork is good in taste and high in nutritional value, and content of a main nutrition ingredient unsaturated fattyacid (docosahexaenoic acid, DHA) can be 20mg/100g. The preparation method is low in energy consumption, equipment investment is low, strains are easy to purchase, the cost is low, learning and operation are easy, and pigs fed by the micro-ecological high-end pig feed ferment powder are healthy and drug-residue-free, so that the aim of producing high-end pork with cost for feeding common pigs is achieved.

The invention relates to a novel composite and a preparation method and application thereof. The novel composite comprises the following components in parts by weight: 0.5-50 parts of Lepidium meyenii walp, 0.5-30 parts of American ginseng, 0.1-20 parts of American ginseng, 5-100 parts of herba epimedii, 1-60 parts of raspberry, 5-100 parts of Rhizoma Dioscoreae, 1-100 parts of silkworm chrysalis, 3-90 parts of Semen Cuscutae, 1-60 parts of Eucommia ulmoides, 3-200 parts of acanthopanax, 5-50 parts of prepared rehmannia root and 2-80 parts of fingered citron. The composition takes effect of treating both principal and secondary aspects of diseases and is specific in effect such as regulating immunity of the organism, improving sexual functions, activating and regulating blood, strengthening tendons and bones, resisting oxidation and delaying ageing of the organism.

The invention belongs to the technical field of toxin expelling and health preserving beverages, and specifically relates to a five element toxin-expelling and health-preserving beverage and a preparation method thereof. The beverage provided by the invention aims at solving the problems that human body shapes and health can be influenced because of a difficult elimination of accumulated stool of human bodies, and the existing toxin-expelling drugs have a single effect of elimination of accumulated stool but no supplement of nutrition, or supplement of nutrition but no elimination of accumulated stool and do not have a long effect on toxin expelling. The five element toxin-expelling and health-preserving beverage is prepared from Cordyceps sinensis, wolfberry, epimeddium, acanthopanax, Ganoderma lucidum, belladonna, gen-seng, Codonopsis pilosula, pilose antler, Poria cocos, mulberry, cassia seed, fleece-flower root, morinda officinalis, root of large-flowered skullcap, prepared rehmannia root, carrot, white radish, white radish leaf, gold mushroom, burdock, green smoked plum, red date, wild jujube, wild jujube root, Chinese yam, brown rice tea, oat tea, grain tea, malt tea and sweet potato. The beverage provided by the invention has the advantages of thorough elimination of toxin, fast action, dual effects of toxin elimination and nutrition supplement, and high absorptivity.

The invention provides a method for extracting and separating cordycepin, belonging to the technical field of intensive process of agricultural products and aiming to solve the problems caused by easily-generated heat in existing cordycepin method that extraction rate and purity are low, only dry samples can be processed while high water content samples are difficult to process. The method comprises the steps of crushing snowflake cordyceps sinensis at low temperature; mixing the obtained material with water in a ratio of 1:5-1:20; after ultrasonic extraction under the condition of 20-30 kHz ultrasonic frequency, mixing and balancing in macroporous resin; purifying by using reverse phase high performance liquid chromatography; and finally obtaining the cordycepin concentrate through desalination using nanofiltration and drying. The method employs low-temperature liquid nitrogen for grinding, combining with low power low-frequency ultrasonic output to promote dissolution, so the mass content of the cordycepin can reach 98-99% at most and the recovery rate can reach 88-90%.

The invention disclose an artificial north aweto culture medium, which contains 33-38g of rice, 9-11g of milk, 17-23g of beef peptone, 0.45-0.55g of potassium dihydrogen phosphate, 4.5-5.5g of pearl powder, 0.25-0.35g of turtle shell powder, 0.25-0.35g of vitamin B1, 0.25-0.35g of vitamin B2, 0.25-0.35g of vitamin C, 0.25-0.35g of vitamin E2, 20-30g of sucrose, 6-10g pupa powder, and 800-1,200g mineral water. The north aweto culture medium and the preparation method thereof have the advantages of high cordyceps conversion, good quality and high yield. The physical and chemical results show that the north aweto contains 2.89% of cordycepin, 8.22% of cordycepin essence, 15.35% of cordycepic acid and 587.85u/mg of SOD enzyme activity, and the contents of north aweto are all higher than that of the natural aweto.

The invention discloses a preparation method of living nutrition powder. The method comprises the following steps: 1, selecting raw materials; 2, drying; 3, extracting; 4, filtering, and centrifuging; 5, carrying out vacuum concentration; and 6, drying. The living nutrition powder prepared in the invention contains a large amount of botanically active selenium, zinc, copper, chromium, rubidium and strontium, also contains multiple trace elements comprising manganese, iron, calcium, magnesium and fluorine beneficial to the health of human bodies and vitamins A, B, C and D, and also contains various amino acids beneficial to the human bodies, comparable with wild ginseng and Cordyceps sinensis in drug effects, so the mashed potato is a most effective selenium, zinc, copper, chromium, rubidium and strontium nutrition optimized-supplementing agent according with Chinese people's physique and absorbing level.

The invention relates to the technical field of corn planting, and particularly discloses a plant fermentation extract for improving corn planting and a preparation method thereof. The plant fermentation extract is characterized in that the plant fermentation extract is prepared from, by weight, 3-4 parts of matsutake, 1-2 parts of radix ginseng, 10-15 parts of Sophora flavescens, 10-15 parts of danshen roots, 5-10 parts of corn stigma, 10-15 parts of seaweed, 3-5 parts of dried tangerine peel, 2-5 parts of eucommia ulmoides, 1-2 parts of cordyceps sinensis, 15-17 parts of radix bupleuri, 0.03-0.05 part of zinc-enriched yeast and 1-2 parts of royal jelly through fermentation, extraction and powder preparation. Raw materials are easy to obtain, the preparation process is simple, and the plant fermentation extract can effectively improve the soil structure, increase the number and activity of effective microorganisms in soil, improve the soil enzyme content, facilitate corn growth, yieldincrease and quality improvement, and is suitable for wide application and popularization.

The invention belongs to the field of microorganism technology, and discloses a cordyceps sinensis fluid medium. The cordyceps sinensis fluid medium is prepared from 50 to 60g of a fibrous material, 50 to 60g of a vinasse hydrolysate, 70 to 80g of potato extraction solution, 30 to 40g of glucose, 2g of magnesium sulfate, 1g of streptomycin, 1g of penicillin, and 0.01g of vitamin B1. A preparationmethod comprises following steps: the above ingredients are delivered into a container, an obtained mixture is diluted with water to 1L, the pH value is adjusted to 6.5 to 6.8, sterilization in an autoclave is carried out, wherein the pressure is maintained for 15min when the temperature is increased to 121 DEG C, an obtained product is taken out from the autoclave, and is cooled to room temperature. The invention also discloses a method used for culturing cordyceps sinensis with the cordyceps sinensis fluid medium. The cordyceps sinensis fluid medium is reasonable in composition, and low in cost; and the quality of cultured products is improved greatly.

The invention relates to a capsule for clearing away turbid and tonifying kidneys. The capsule is prepared from the following raw materials by weight: 100g of cordyceps sinensis, 1400g of astragalus membranaceus, 280g of root of red-rooted salvia, 280g of flowers carthami, 280g of spina date seeds, 500g of semen cuscutae and 100g of rheum officinale. The applied capsule for clearing away turbid and tonifying the kidneys is used for treating both deficiency and excess and treating both symptoms and root causes, is accurate in curative effect, rigorous in formula, and simple and convenient to prepare, and has a broad application prospect.

The invention relates to a cordyceps sinensis freshness-retaining product taking Nitraria tangutorun polysaccharide as a natural bacteriostatic agent. The product is obtained by the steps of soaking 0.4g-0.8g of fresh cordyceps sinensis after sterilization treatment in a Nitraria tangutorun polysaccharide bacteriostatic agent with concentration of 5-10mg/ml and volume of 20mL, and then canning and sterilizing. The invention further discloses a preparation method of the product. According to the invention, the phenomenon of intoxication caused by adding of a chemical preservative is avoided, and Nitraria tangutorun polysaccharide plays a role of biological preservation and endows a certain physiological effect to the product, so that the product has the characteristics of being pure natural, green and safe.

The invention relates to an adenosine monophosphate (AMP) adenosine deaminase for synthesizing and metabolizing an inosine monophosphate from adenine nucleotide of Cordyceps sinensis(Berk.)Sacc. Hirsutella sinensis from 'Bailing' production strain, a gene coding the enzyme and application thereof. The AMP adenosine deaminase comprises the proteins shown in SEQ ID No. 1 and SEQ ID No. 2, and the coding gene of the AMP adenosine deaminase corresponds to the nucleotide sequence shown in SEQ ID No. 3 and SEQ ID No.4. According to the invention, the metabolizing way for synthesizing the inosine monophosphate from the adenine nucleotide is researched in detail from the principle, and the cloned DNA containing the nucleotide sequence provided by the invention can be transferred to an engineering strain by transduction, transformation, and combined transfer; the expression of the gene is biologically synthesized by regulating the inosine monophosphate, the host inosine monophosphate is endowed with high expressivity, an effective way is provided for increasing the yield of the inosine monophosphate, and the invention has a great application prospect.

The invention relates to a method capable of improving yield and quality of cordyceps sinensis. The method comprises the following steps: strain slant cultivation, primary fermentation, secondary fermentation and a solid-liquid separation process, wherein each of the primary fermentation and the secondary fermentation is divided onto an initial fermentation stage and a later fermentation stage; when the initial fermentation stage is ended, the later fermentation stage is entered after the material supplementing operation; at the initial fermentation stage and the later fermentation stage, a culture medium of a carbon source and a nitrogen source which are in different concentration ratio is adopted for fermentation. According to the artificial fermentation method disclosed by the invention, the yield and the quality of the product are improved, the fermentation period is shortened, and good economic benefits are brought for artificial industrial production of cordyceps sinensis.

[PROBLEMS] To provide a fraction containing the active ingredient contained in plant worms. To provide a means efficacious in immunopotentiation, an effective means of preventing or treating cancer and a composition useful in producing health foods. [MEANS FOR SOLVING PROBLEMS] It is intended to provide a precipitation fraction obtained by extracting plant worms mycelium with hot water and adding ethanol to the thus obtained extract. It is also intended to provide a composition for oral intake which contains the above precipitation fraction. It is further intended to provide foods, drinks, immunopotentiators, anticancer agents and so on containing the above composition for oral intake which are characterized by having an anticancer effect, an effect of preventing cancer or an immunopotentiation effect. It is furthermore intended to provide a method of effectively producing the above-described composition for oral intake.

The invention discloses a beauty and skincare capsule which is prepared by soaking, fermenting, grinding and filling 3 parts of fermentative cordycep fungal powder, 1 part of ganoderma lucidum powder, 1 part of lentinus edodes powder and 0.5-0.8 part of Brazil nut powder. According to the beauty and skincare capsule, four substances including fermentative cordycep fungal powder, ganoderma lucidum powder, lentinus edodes powder and Brazil nut powder work together to protect and repair the skin in an omnibearing manner, proper crosslinking formed by collagen can be promoted, an active oxygen free radical scavenger is inhibited, water-oil balance of the skin is adjusted, skin ageing is prevented, soft and smooth skin is kept, the collagen and elastin can also be stabilized, and the skin has elasticity. In addition, the beauty and skincare capsule also has the functions of detoxication and elimination of toxicants, and lesion or degeneration of the skin is prevented.

The invention belongs to the technical field of pharmacy, and particularly relates to a blood glucose reducing composition and application thereof. The composition is prepared from the following components in parts by weight: 10-30 parts of cordyceps sinensis, 50-80 parts of ginseng, 150-200 parts of fructus swietenia macrophylla, 30-60 parts of bitter gourd and 25-55 parts of cactus. The blood glucose reducing composition has the beneficial effects that regarding treatment on type 2 diabetes, the relationship among liver, bile, pancreas, stomach and kidney can be comprehensively balanced, the comprehensive metabolic capability can be gradually improved, the hemoglobin level can be smoothly restored and reduced, and the status of diabetic complications can be reduced. The blood glucose reducing composition does not have toxic or side effects, and is safe and reliable for long-term administration.

The invention relates to a medicinal preparation and a preparation method thereof and in particular relates to a compound Chinese medicament for treating cancer and a preparation method thereof. The compound Chinese medicament for treating cancer is produced into spray and aerosol, the sprayed mist-state liquid is mixed with negative oxygen ions to both act on the nasal cavity, or directly produced into oral solution. The medicament is prepared from fermentative cordycep fungal powder and ganoderma lucidum powder at a weight ratio of 1:(0.8-1.2). The preparation method comprises the following steps: weighing the fermentative cordycep fungal powder and ganoderma lucidum powder according to the weight ratio; sealing with deionized water and heating to 80-100 DEG C, extracting for 1 hour, and filtering to obtain an extract; sealing with deionized water and heating to 80-100 DEG C, filtering to obtain an extract; combining the two extracts, heating to 80 DEG C, concentrating into a medicinal concentrated solution; and cooling to normal temperature to prepare the medicinal concentrated solution of the compound Chinese medicament for treating cancer.

The invention relates to an inosine monophosphate (IMP) dehydrogenase from 'Bailing' producing strain Cordyceps sinensis Hirsutella sinensis for participating in anabolism on IMP to obtain a xanthylic acid, a gene for encoding the dehydrogenase and application of the dehydrogenase. The IMP dehydrogenase comprises a protein shown by SEQ ID No.1 and a protein shown by SEQ ID No.2, and the coding gene of the protein shown by SEQ ID No.1 and the coding gene of the protein shown by SEQ ID No.2 respectively correspond to a nucleotide sequence shown by SEQ ID No.3 and a nucleotide sequence shown by SEQ ID No.4. According to the invention, the metabolic pathway of the IMP to synthetize the xanthylic acid is traversed from the principle; the cloning deoxyribonucleic acids (DNA) of the nucleotide sequences provided by the invention can be transferred into engineering bacteria through a transduction method, a transformation method and a conjugal transfer method; and through regulating the expression of the biosynthetic gene of the xanthylic acid, the high expressivity of a host xanthylic acid is endowed, and an effective way for increasing the yield of the xanthylic acid is provided. The IMP dehydrogenase has a great application prospect.

The invention relates to a delta-5-desaturase from a Corbrin-production bacterium cordyceps sinensis hirsutella sinensis. The delta-5-desaturase participates in eicosapentaenoic coenzyme A anabolism started from eicosatetraenoic coenzyme A. The invention also relates to a gene coding the enzyme, and an application thereof. The amino acid sequence of the delta-5-desaturase has more than 90% homology with a sequence represented by SEQ ID No.1 or SEQ ID No.3. From the principle, the invention carries out detailed researches upon the metabolic pathway of eicosatetraenoic coenzyme A to synthesizing the eicosapentaenoic coenzyme A. A cloned DNA comprising the nucleotide sequence provided by the invention can be transferred to engineering bacteria through methods of transduction, transformation, and combined transferring. Through the regulation upon eicosapentaenoic coenzyme A biosynthetic gene expression, high expression of a host delta-5-desaturase is provided, an effective approach is provided for increasing eicosapentaenoic acid yield. The application has an important application prospect.

The invention discloses a liquid crystal slow-release system for promoting transdermal absorption of cordyceps sinensis as well as a preparation method and an application thereof. A liquid crystal skin care system comprises a liquid crystal sustained-release system and a cordyceps sinensis extract, the liquid crystal slow-release system comprises a liquid crystal emulsifier, fatty alcohol, polyol,grease, a skin conditioner and water, and the mass content of the cordyceps sinensis extract in the liquid crystal skin care system is 1-10%. The liquid crystal skin care system has the advantages that through the synergistic effect of the liquid crystal slow-release system and the cordyceps sinensis extract, a liquid crystal structure can enable cordyceps sinensis cyclic peptide, cordyceps polysaccharide, cordycepic acid, cordycepin adenosine and SOD enzyme which serve as cordyceps sinensis active matters to sequentially permeate into an epidermal layer, a basal layer and a corium layer, sothat the activity of the active matters is fully exerted, the transdermal absorption rate is improved, and the effects of protecting a barrier, whitening, moisturizing and resisting ageing are achieved.