85 results about "P-methoxybenzaldehyde" patented technology

The invention relates to a mixture of compounds having the sensory properties of winter-green, to fragrance and flavoring compositions containing said mixture and to flavored and perfumed products containing said mixture, to a method of adding a wintergreen flavor, odor or note to (non-wintergreen) flavored or perfumed products. Further the present invention relates to the use of said mixture as an enhancement, or as complete or partial replacement for methyl salicylate, in particular in chewing gum, foods, dentrifices, mouthwashes and other orally consumable products. The mixture comprises or consists of dihydroanethole, o-anisaldehyde, 1,3-dimethoxybenzene, 2′-hydroxyacetophenone, and optionally 2-methoxyacetophenone.

The present invention relates to oral care compositions comprising stannous ions, a mint-type flavor oil, a protectant component that prevents generation of off odor and off taste in the composition, and orally acceptable carriers. The mint-type oils include peppermint, spearmint and corn mint. Suitable protectant components include copper salts and carbonyl compounds such as ascorbic acid; cis-jasmone; 2,5-dimethyl-4-hydroxy-3(2H)-furanone; 5-ethyl-3-hydroxy-4-methyl-2(5H)-furanone; vanillin; ethyl vanillin; anisaldehyde; 3,4-methylenedioxybenzaldehyde; 3,4-dimethoxybenzaldehyde; 4-hydroxybenzaldehyde; 2-methyoxybenzaldehyde; 4-methoxybenzaldehyde; benzaldehyde; cinnamaldehyde (3-phenyl-2-propenal); hexyl cinnamaldehyde; α-methyl cinnamaldehyde; ortho-methoxy cinnamaldehyde; α-amyl cinnamaldehyde; and combinations thereof. The oral care composition may be a dentifrice.

The invention discloses a preparation method for (Z)-3'-hydroxyl-3,4,4',5-tetramethoxyl diphenyl ethylene. A diphenyl ethylene framework structure is built by the Perkin reaction method, and natural aniseed fat-soluble components and propenyl anisole (anethole) are taken as raw materials, and oxidized to obtain anisaldehyde; dichlorocarbene insertion reaction is carried out on the anisaldehyde to obtain p-methoxyl-mandelic acid which is reduced to obtain methoxyl-phenylacetic acid, the methoxyl-phenylacetic acid is brominized to obtain 3-bromo-4-methoxyl-phenylacetic acid. The compound and the natural 3,4,5-trimethoxybenzaldehyde (nutgall extract derivative) carry out Perkin reaction to build a cis-form diphenyl ethylene framework which is further converted and decarboxylated by functional groups to obtain the (Z)-3'-hydroxyl-3,4,4',5-tetramethoxyl diphenyl ethylene. The raw materials of the invention are reproducible natural resources-anethole which are rich in China and 3,4,5-trimethoxybenzaldehyde, and replace non-renewable petrochemical materials which are used by the prior art and become less and less so that the method has the advantages of good sustainable development capability as well as remarkable economic, environmental and ecological benefits.

The invention relates to a co-production method for preparing corresponding alcohol, ester, aldehyde and acid by oxidizing p-methoxyl methylbenzene by oxygen. The method comprises the following steps: adding p-methoxyl methylbenzene, a catalyst I and a solvent into an oxidizing reaction kettle, and introducing oxygen to react; after oxidizing reaction, recovering the solvent and optionally selecting to apply mechanically, and then adding water to wash the catalyst I to obtain an organic phase I and an aqueous phase I; adding alkali into the organic phase I, decompressing and evaporating an organic phase II, after adding water to the bottom, adjusting the pH value by an acid, and filtering to obtain p-methoxybenzoic acid; distilling the water phase I to recover water, optionally selecting to apply mechanically, further adding the catalyst I and the solvent at the bottom, and optionally selecting to apply mechanically in oxidizing reaction; rectifying the organic phase II to obtain a product p-methoxybenzaldehyde and anisyl acetate; carrying out basic hydrolysis on anisyl acetate to obtain an anisic alcohol crude product; and rectifying to obtain an anisic alcohol pure product. The co-production method provided by the invention has the advantages of greenness and environment protection, mild reaction condition, low cost and less three waste, and is easy to industrially produce, and the obtained product is widely applied to the fields of foods, medicines and daily chemicals.

Hydrophobically modified sodium alginate is obtained via acetalation reaction of sodium alginate with p-anisaldehyde (also called anisic aldehyde) in acid-catalyzed condition, and is prepared to be gel. Analysis of the product is performed by using fluorescence, transmission electron microscopy, scanning electron microscopy, UV, and thermal analysis, and analysis results shows that the anisic aldehyde successfully reacts with the sodium alginate. The gel can be used as a drug carrier for embedding and releasing bovine serum albumin, and results shows that drug loading ratio and releasing performance of the modified product are improved by some extent compared with the unmodified sodium alginate. The product of the present invention can be used as a drug carrier material to apply in the medical field.

The invention relates to lemon essence for water-based ink. The lemon essence is prepared from, by weight, 1%-30% of lemon essence, 5%-55% of compound modification oligosaccharide and deionized water. The lemon essence is composed of lemon oil, litsea cubeba oil, citral diethyl acetal, myrac aldehyde, bergamot aldehyde, lemonile, decanal, caprylic aldehyde, dodecanenitrile, citonellye nitrile, ethyl methylphenylglycidate, linalyl acetate, linalool, lilial, benzyl acetate, cyclamen aldehyde, terpilenol, terpinyl acetate, anisic aldehyde, verdyl acetate, geraniol, geranyl acetate, citronellol, citronellyl acetate, isocyclocitral, styralyl acetate, isoeugenol, ionone, heliotropin, iso-longitolanone, HHCB and ethyl alcohol. The invention further provides a preparation method of the lemon essence for the water-based ink. According to the lemon essence for the water-based ink and the preparation method of the lemon essence, the compound modification oligosaccharide is used as a wall material, the lemon essence is wrapped so that lemon nanocapsule slow-release essence can be formed, and therefore fragrance depositing and water solubility of the essence are improved.

The invention discloses a carbazolyl porous organic polymer-carried transition metal oxide catalyst and a method for preparing p-methoxybenzaldehyde by oxidizing p-methoxytoluene. The carbazolyl porous organic polymer-carried transition metal oxide catalyst is prepared by taking carbazolyl porous organic polymers as the carrier, carrying transition metal oxides on the carrier and performing calcination. The skeleton of the carbazolyl porous organic polymers is provided with uniformly-distributed nitrogen atoms, which can to some extent interact with metal, so that the uniformly-distributed nitrogen atoms can activate the active sites of the metal oxides on the one hand and reduce loss of active components during reaction on the other hand. The carbazolyl porous organic polymer-carried transition metal oxide catalyst can efficiently catalyze p-methoxytoluene to prepare p-methoxybenzaldehyde and achieve a conversion rate and selectivity up to higher than 70%. Compared with traditional heterogeneous catalysts, the carbazolyl porous organic polymer-carried transition metal oxide catalyst is high in thermal stability, better in catalytic activity, less prone to loss of active componentsand longer in service life.

The invention relates to a preparation method of 5,6,7,4'-tetramethoxy flavone of scutellarin and aglucone key intermediate thereof. The 5,6,7,4'-tetramethoxy flavones is prepared by utilizing 2-hydroxyl-4,5,6-trimethoxy hypnone as the raw material and comprising a reaction a step and a reaction b step, wherein in the reaction a, 2-hydroxyl-4,5,6-trimethoxy hypnone and p-methoxybenzaldehyde are condensed to prepare a chalcone derivative; and in the reaction b, the chalcone derivative is processed in a oxidative cyclization mode to prepare the 5,6,7,4'-tetramethoxy flavone. The method has the advantages of simple operation steps and high product yield.

The invention discloses a thrip attractant and an application thereof. The thrip attractant is prepared from ethyl 3-pyridinecarboxylate, anisaldehyde, p-tolualdehyde and p-methoxybenzaldehyde in a mass ratio being (1-20):(1-20):(1-20):(1-10) through mixing; the substances are dissolved in n-hexane and slowly released in a carrier, lure is prepared, and the lure carrier of the thrip attractant is suspended on a blue or yellow pest sticking board. Control tests indicate that under the application of the thrip attractant, the control effect is similar to that of independently applied pesticides, and the control effect can be improved 3-4.5 times compared with that of the independently applied pest sticking board. When applied to control for thrips, the thrip attractant has the characteristics of being stable in product performance, long in persistent period, efficient and environment-friendly, luring numerous varieties and the like, the use quantity of chemical pesticides is substantially reduced, the damage rate of vegetables, fruits or flowers is also effectively controlled, sustainable development of green products is promoted, and a new thought is provided for the integrated control technique of thrip pests.

A method for preparing anisaldehyde by using natural anethole as a raw material comprises the following steps: 1, mixing natural anethole, ethanol and water to obtain a reaction raw material, adding the reaction raw material into a three-neck bottle, letting in a certain volume of oxygen, and carrying out an oxidation reaction to obtain a reaction product containing anisaldehyde; and 2, carrying out liquid separation treatment of a mixed solution, taking the obtained upper layer liquid, distilling the upper layer liquid to remove an organic solvent in order to obtain crude anisaldehyde, extracting the obtained lower layer liquid by an organic solvent, distilling the obtained extract liquid to obtain crude anisaldehyde, mixing the above obtained two groups of crude anisaldehyde, and rectifying the above obtained crude anisaldehyde mixture to obtain anisaldehyde. The method lays an environmentally friendly foundation for producing anisaldehyde.

The invention relates to a method for preparing p-methoxybenzaldehyde perfume in presence of metalloporphyrin through catalytic oxidation of p-methoxytoluene. The method comprises the steps of: by taking metalloporphyrin with the concentration of 10-100ppm as a catalyst, N-hydroxyphthalimide as a free radical initiator and, introducing oxygen under 0.1-1.0Mpa and reacting for 1-12h at 60-100 DEG C in an acetonitrile solvent to obtain p-methoxybenzaldehyde, wherein the molar ratio of N-hydroxyphthalimide to p-methoxytoluene is (0.01-0.1):1. The method has the advantages that the consumption of the catalyst is extremely low, separation and recovery are not needed, the catalyst is higher in activity and selectivity, and a reaction condition is mild. According to the method provided by the invention, not only can resources be utilized and saved effectively, but also environmental pollution is reduced and the purpose of reducing energy consumption is achieved to further realize energy saving and emission reduction in an all-round way, and thus, the method has a wide application prospect in the industry.

The invention discloses a preparation method of anisic aldehyde. The preparation method comprises the following steps: 1, firstly adding N,N-dimethyl formamide and pyridine in a reaction kettle, then at a low temperature, dropping triphosgene dissolved by chloroform and carrying out a reaction, after dropping of triphosgene is finished, carrying out heat preservation, and continuing the reaction for 0.2-1 h; 2, keeping the low temperature, adding aluminum trichloride into the reaction liquid in batches, and after completing addition of aluminum trichloride, carrying out heat preservation for 0.2-1 h; 3, steaming out chloroform in the kettle, making the kettle temperature reach 60-100 DEG C, and slowly dropping anisole with keeping the temperature; 4, after completing dropping of anisole, continuing to heat and stir for 6-10 h at the temperature of 60-100 DEG C; and 5, after the reaction is finished, quenching the reaction liquid with a liquid caustic soda solution, washing, extracting, desolventizing, and rectifying to obtain the final product anisic aldehyde. The method has the characteristics of simpleness, easy control and industrialized production; and the produced anisic aldehyde is safe and stable, and the production efficiency is improved.

The invention discloses purple yam essence, and a preparation method and application thereof. The purple yam essence is prepared from 2,3,5-trimethyl pyrazine, 2,3-dimethylpyrazine, dimethyl sulfide, butanedione, 3-hydroxy-2-butanone, 3-methylthiopropanal, 2-acetylpyrazine, 3-methylthio-propanol, butyryl butyl lactate, gamma-heptalactone, gamma-caprylolactone, ethyl maltol, maltol, anisic aldehyde, gamma-nonalactone, ethyl myristate, gamma-decalactone, delta-decalactone, mercaptan, delta-dodecalactone, ethyl vanillin, vanillin, trans-2-ethoxy-5-phenol and vanilla bean tincture are used as the main raw materials. the purple yam essence is prepared by adding all the raw materials into a container and uniformly agitating and mixing to obtain the purple yam essence. According to the purple yam essence, the raw materials are rich in source, so that the purple yam essence is coordinated and soft in aroma, has the natural featured aroma of prepared henry steudnera, and is rich in aroma, long in lasting time and stable. The purple yam essence can be used for adding the aroma of cakes, ice cream, milk products, drink and other products.

The invention discloses a synthetic process for p-methoxybenzaldehyde. The synthetic process comprises methylation reaction with p-hydroxybenzaldehyde as a raw material, methyl chloride gas as a methylation raw material and water as a solvent according to a certain feeding proportion. According to the invention, methyl chloride gas is used as the methylation raw material, so reaction is single; selectivity is up to 95%; yield of a target product reaches more than 90%; meanwhile, treatment of three wastes is simple, so the process belongs to clean and green chemical synthetic process.

What is provided includes a porous sol-gel material whose intrinsic pH is lower than 1 and comprising at least one probe molecule chosen from the group consisting of croconic acid, p-dimethyl-aminobenzaldehyde (DMABA), p-dimethyl aminocinnamaldehyde (DMACA), p-methoxybenzaldehyde (MOB) and 4-methoxy-1-naphtaldehyde (MON). In addition, a detection system containing the porous sol-gel material and a method of preparation and use of the porous sol-gel material for trapping and / or detecting and optionally quantifying at least one chemical compound such as indole and indole compounds are provided.

The invention relates to a method for preparing p-methoxybenzaldehyde by p-methoxybenzoic acid, which comprises the following steps: adding p-methoxybenzoic acid, o-phenylenediamine and a solvent in a condensation reaction kettle, wherein a catalyst is not used in the step, performing backflow water distribution when no water is generated; cooling, filtering to obtain 2-(4-methoxyphenyl)benzimidazole; adding a catalyst, absolute methanol and 2-(4-methoxyphenyl)benzimidazole in a hydrogenation reaction vessel, setting reaction temperature and hydrogen pressure, performing a hydrogenation reaction when hydrogen is unabsorbed, cooling to room temperature; recovering methanol from a filtrate, adding a sulfuric acid aqueous solution, performing backflow for reaction, then cooling to the temperature of 60-65 DEG C, separating the liquid to obtain an oil layer and a water layer, washing the oil layer to neutrality, and rectifying to obtain the final product. The preparation method has the advantages of mild reaction condition, low cost, less three wastes and easy realization of industrial production.

The invention discloses a preparation method of p-methoxybenzaldehyde, wherein the preparation method includes following steps: (A) with p-hydroxybenzaldehyde and dimethyl carbonate as raw materials, immobilized TEBA as a catalyst and chloroform as a solvent, adding sodium carbonate and performing a reaction under a microwave / ultrasonic combination condition; (B) adding 1-2 mol of p-hydroxybenzaldehyde, 1.5-3 mol of dimethyl carbonate, 3-5 mol of chloroform to dissolve the raw materials, adding 0.05-2 mol of the immobilized TEBA and 0.1-0.5 mole of sodium carbonate, and performing a reflux reaction under a microwave and ultrasonic condition; (C) when the solution is boiled and reflux liquid begins to drop from a condenser, regulating a heat source to enable reflux speed to be normal; (D) when the reaction is finished, cooling the liquid to room temperature, performing filtration to recycle the sodium carbonate, moving a filtrate to a distillation flask, performing pressure-reduced fractionation to remove the top layer liquid, and performing pressure-reduced distillation to collect the fraction in the range of -0.098 MPa - 0.1 MPa and 100-120 DEG C to obtain p-methoxybenzaldehyde. The method is simple in operations and is less in by-product. The catalyst is low in cost, is easy to obtain and is less in pollution. The method is low in requirement on production equipment and is suitable for being carried out in large-scale production.

The invention provides a selective synthesis method of diltiazem chiral intermediate. The method is as below: using anisic aldehyde, chloroacetyl chloride and L-menthol as raw materials; first subjecting chloroacetyl chloride and L-menthol to an esterification reaction to obtain an intermediate 1; then subjecting the intermediate 1 with anisic aldehyde to a Darzens condensation reaction to produce diastereomer intermediates 2 and 3; refining to obtain an optically pure intermediate 3; reacting the intermediate 3 with o-aminothiophenol to obtain an intermediate 4; hydrolyzing the intermediate 4 to obtain an intermediate 5; and cyclizing the intermediate 5 to obtain a product. The invention has the advantages that the ester formed by chloroacetyl chloride and L-menthol is selective in the Darzens condensation reaction with anisic aldehyde to generate the more target product, and solubility difference between the target product and the isomer is used to directly obtain optically pure intermediate, without a complicated resolution process, and the yield is greatly improved. The method substantially increases the utilization rate of the main raw material anisic aldehyde and reduces cost.

The invention provides a method for preparing apigenin, which comprises the following steps: performing the condensation reaction of the raw material of 2,4-dimethoxy-6-hydroxyacetophenone with p-methoxybenzaldehyde with the catalysis of an alkali to obtain a compound II; performing the cyclization reaction with the presence of a catalyst to obtain a compound III; heating to remove the methoxy group at an oxygen-isolated and acidic condition so as to obtain apigenin. The invention prepares apigenin by chemical synthesis, and has the advantages of simple process, easy processing for product separation and purification, high yield, mass production potential, abundant raw material sources, and low cost.

The invention discloses cherry essence and essence microcapsules. The cherry essence comprises musk, abelmoschus esculentus lactone, methyl dihydrojasmonate, triethyl citrate, gamma-undecalactone, phenyl-1-hexanol, 3-Methyl-3-phenylglycidic acid ethyl ester, phenoxyethyl isobutyrate, dimethyl benzyl carbinyl butyrate, beta-ionone, natural anisylacetone, fructose ester, ethyl vanillin, tricyclodecenyl acetate, damascenone, methyl cinnamate, phenylethyl acetate, blackcurrant essence, high-cis o-tert-butyl cyclohexyl acetate, anisic aldehyde, phenoxyethanol, ethyl maltol, styrallyl acetate, ligustral, isononyl acetate, benzyl acetate, benzaldehyde, hexyl acetate, ethyl 2-methylvalerate, 2-methyl butyl acetate and the like. The cherry essence prepared by the invention not only has strong cherry fragrance, but also has natural soft feeling and high harmony, and the cherry essence microcapsules prepared by taking the cherry essence as a raw material can keep excellent flavor quality of the cherry essence in long-term storage.

The invention relates to a process for preparing food of shredded pepper, wherein the constituents of the raw materials include (by weight percent) shredded pepper 30-50%, Artemsia dracunculus L. 10-20%, edible oil 20-30%, pricklyash peel 1%, piper nigrum 0.1%, gourmet powder 2-5%, salt 3-5%, soy sauce 5-10%, and balancing water. The food contains nutrients including carotene, vitamin C, alkaloid and volatile oil of sabinene, geraniolene and anisaldehyde.

The invention relates to a medical suture and a preparation method thereof. The medical suture consists of the following ingredients in parts by mass: 35-55 parts of polyglycollide, 3-16 parts of chitin, 2-13 parts of collagen fibers, 1-8 parts of pigskin collagen, 0.5-4.5 parts of sodium alginate, 0.3-1.5 parts of glucose, 0.5-2.5parts of anisaldehyde, 0.1-0.4 parts of sodium polyacrylate, 0.1-0.4 parts of saccharin, 0.2-0.8 parts of nano cellulose, 0.1-0.5 parts of vinyl silicon oil, 0.1-0.4 parts of polytetrafluoroethylene and 0.1-0.4 parts of glutaraldehyde. The medical suture provided by the invention is excellent in degradation and absorption properties as well as biocompatibility; meanwhile, the medical suture can develop a bacteriostatic effect for a long time; and the medical suture, after being used for stitching wound, is free from the generation of inflammations and is not easy to cause scars.

The invention relates to an industrial sewage treating agent which comprises the following components in parts by mass: 20-40 parts of anisaldehyde, 20-40 parts of sodium borate, 10-30 parts of montmorillonite, 15-30 parts of sodium gluconate, 40-60 parts of zinc acetate, 10-20 parts of benzoin ethyl ether, 20-40 parts of active diatomite, 5-15 parts of dimethyl diallyl ammonium chloride, 10-30 parts of triethylammonium acetate and 50-100 parts of deionized water. The industrial sewage treating agent is high in reaction speed and does not generate hazardous gas in the reaction process; the product generated after reaction is stable and cannot be decomposed into toxic substances; the industrial sewage treating agent is efficient and nontoxic, is safe to a human body before and after reaction, and is non-corrosive to equipment; the use method of the industrial sewage treating agent is simple and convenient, the process flow is not changed, and no extra equipment or additional material is needed; the sewage treatment effect is obvious and the industrial sewage treating agent is convenient to use.

The invention relates to a method for preparing para methoxy phenyl acetonitrile, which comprises the following steps: firstly adopting p-methoxybenzaldehyde as the raw material to generate anisyl alcohol under the action of a reducing agent; after drying the obtained reaction product, carrying out chlorination on the dried reaction product by thionyl chloride to obtain benzyl chloride; and carrying out cyanoethylation reaction on the obtained benzyl chloride under the alkaling conndition and under the action of a phase transfer catalyst to obtain the para methoxy phenyl acetonitrile, wherein the total yield of the para methoxy phenyl acetonitrile reaches over 85 percent.

The invention relates to the field of essence, and particularly discloses oriental flower flavored essence and a preparation method thereof. The oriental flowery flavor essence consists of a main flavor, a modifier, a mixing agent, a fixative and a solvent. The main flavor is prepared from the following components: linalool, benzyl alcohol, phenethyl alcohol, benzyl acetate, methyl anthranilate, methyl benzoate, methyl salicylate, iso-methyl ionone, alpha-hexylcinnamic aldehyde, anisic aldehyde, hydroxycitronellal, undecan-4-olide, specially pure vanillin, ethyl maltol, eugenol and limonene. The modifier is prepared from the following components: cinnamic alcohol, rose ether and cedar wood oil. The oriental flower flavored essence has the advantages that the oriental flower flavored essence has a comfortable and natural feeling while generating complicated fragrance change.

The invention belongs to the technical field of chemical application, and particularly relates to a method for preparing anisaldehyde through micro-channel continuous ozone oxidation. According to themethod, anethole is used as a raw material, ozone is used as an oxidizing agent, sodium hydrogen sulfite is used as a reducing agent, micro-channel equipment is adopted for mixing, a continuous reaction is carried out, anise oil is oxidized by ozone in the presence of a solvent or in the absence of a solvent, oxydol is reduced by sodium hydrogen sulfite, and the target product anisaldehyde is obtained. Compared with the present synthesis technology in the prior art, the method has the advantages of realization of continuous reaction, easiness in automatic control, simplicity, convenience andsafety in operation, mild reaction conditions, few byproducts, low cost and less pollution and is suitable for industrial production.

The invention provides a method for preparing and purifying a diltiazem chiral isomer. The method comprises the steps of taking p-methoxybenzaldehyde as a starting raw material, carrying out Darzens condensation, a reaction with o-aminobenzenethiol and a cyclization reaction to prepare an intermediate, carrying out chiral column separation on the intermediate, then carrying out an alkylation and acetylation reaction separately to obtain a diltiazem chiral isomer impurity I. The method is simple to operate and short in period, and the purity of the obtained diltiazem chiral isomer impurity is high, so that a reference substance is provided for quality research and drug synthesis process research of diltiazem drugs, and the method has important significance in control and checking of the chiral purity in the pharmaceutical research of diltiazem.

The invention relates to a glue-spraying type pest attractant. The attractant comprises the following components in parts by weight: 90-95 parts of pest sticking glue, 3-8 parts of insect pheromone, 0.1-3 parts of 3-phenylpropionaldehyde and 0.1-3 parts of eucalyptol. The insect pheromone is prepared from anisaldehyde, p-tolualdehyde, ethyl 3- piperidinecarboxylate, 4-anisaldehyde, citronellol andeugenol according to the mass ratio of (1-15):(1-15):(1-15):(1-5):(1-5):(1-5). According to the invention, the compounded 3-phenylpropionaldehyde and the eucalyptol are used as plant-source synergists and can improve the attracting effect of the insect pheromone by 20%-35%. Meanwhile, the oily glue is utilized as a release agent and is sprayed on appliance surfaces, and when a diluent is volatilized, the high binding character of the colloid is utilized for high efficiently attracting and killing pests. The pest attractant provided by the invention meets the urgent requirements of glue-spraying type pest attractants with no public nuisance, high efficient attraction, good stickiness, high strength, good stability, simple and convenient operation and low cost on the market, and has a widemarket prospect.