The invention discloses an efficient synthetic method for medicinal high-purity dehydrocholic acid. The method is characterized by comprising the following steps: A,
cholic acid is evenly dispersed by using
acetone, then concentrated
sulfuric acid is added for dissolving;
sodium hypochlorite is dripped, after the reaction is finished, water is added for mixing and filtering, and is used for washing until the neutral property is obtained, and then the
drying is implemented to obtain a crude
redox product; and B, after the
acetone is added in the crude product of the step A for dissolving, enough
silica gel is added for absorbing acid and
cholic acid derivative of the crude product, after the absorption is finished,
acetone solution of the dehydrocholic acid is obtained through filtering, the acetone solution is dried by
distillation, and is added with
sodium hydroxide solution for dissolving, then
acetic acid solution is dripped, and is crystallized to separate out a dehydrocholic acid
crystal, and then the
filtration and the
drying are implemented to obtain the finished product. The invention aims to overcome the defects in the prior art, and provides the efficient synthetic method for the medicinal high-purity dehydrocholic acid; and the method has the advantages of simple technique, high product purity, high yield, lower production cost, safety and reliability.