The invention discloses a tellurobismuthite leaching method. The method comprises the steps that crude tellurobismuthite is subjected to crushing treatment, and grinding is conducted to enable the particle size to meet the requirement that 90% of ore powder can pass through a 200-mesh sieve; treated tellurobismuthite is put into a roasting furnace, roasting is conducted for 4 h to 6 h at the temperature ranging from 400 DEG C to 450 DEG C, and tellurobismuthite subjected to roasting is collected; grinding is continuously conducted to enable the particle size to meet the requirement that 90% of ore powder can pass through the 200-mesh sieve, pretreated tellurobismuthite is put into a sulfuric acid medium, ozone with the concentration ranging from 10 mg/h to 50 mg/h is introduced, an appropriate amount of surfactant is added, leaching is conducted at 70 DEG C to 80 DEG C, and leachate is obtained, wherein 100 r/min to 200 r/min mechanical stirring is conducted in the leaching process, and the leaching stirring time ranges from 3 h to 4 h. According to the tellurobismuthite leaching method, the technological process is simple, operation is convenient, no special equipment requirement exists, the cost is low, the method is suitable for industrial scale production, the leaching rate of tellurium is 98% or above, the leaching rate of bismuth is 97% or above, and tellurium and bismuth in tellurobismuthite are fully leached; meanwhile, leached leachate provides a good condition for extraction of downstream tellurium and bismuth.