The invention discloses a refractory sintered clay hollow brick, and belongs to the technical field of hollow bricks. The refractory sintered clay hollow brick comprises the following raw materials in parts by weight: 55 to 60 parts of clay, 12 to 16 parts of attapulgite, 10 to 14 parts of silica fume, 8 to 12 parts of glass fibers, 18 to 20 parts of ceramic microbeads, 5 to 9 parts of cement, 3 to 5 parts of corundum powder, 3 to 5 parts of quartz powder, 4 to 6 parts of aluminum oxide, 7 to 9 parts of yttrium oxide, 6 to 8 parts of brominated epoxy resin, 2 to 4 parts of organic bentonite, 1 to 3 parts of starch, 2 to 4 parts of chlorinated paraffin, 4 to 5 parts of melamine cyanurate, 5 to 6 parts of tricresyl phosphate, 1 to 3 parts of antioxidants, 1 to 2 parts of water reducers, 1 to 3 parts of preservatives and an appropriate amount of water. The invention further discloses a preparation method of the refractory sintered clay hollow brick. The refractory sintered clay hollow brick disclosed by the invention is simple to prepare, corrosion resistant and heat-insulated, relatively high in strength and fire resistance, and long in service life.