93 results about "P-toluidine" patented technology

The invention relates to a hole-transporting blue color compound, which is a fluorine derivative based on 9, 9-bi-(4-(bi-p-methypheny) aminophenyl). The preparation method is to first mix 9, 9-bi-[4-(N, N-bi-p-toluidine) phenyl]-2-dibromofluorine and boric acid pinacol ester of conjugate radicle, or to mix 9, 9-bi-[4-(N, N-bi-p-tolyl-amino) phenyl] fluorine -2, 7-bi-boric acid pinacol ester and bromide of conjugate radicle; and then add in toluene, potash solution, aliquat336 and catalyst tetrakis (triphenylphosphine) palladium, and heat and reflow for 10 to 30 hours in nitrogen environment; when the reaction is done, decompress, remove the solution and get the target product, the derivative based on 9, 9-bi-(4-(bi-p-methypheny) aminophenyl) fluorine substituted by unilateral conjugate radical. The compound can be used as the hole-transporting layer and the luminescent layer as well in electroluminescent devices.

The invention discloses a gene detecting film strip for multiple bacteria and a primer thereof. Ten common bacteria are selected as detected objects and 16SrRNA (Ribosomal Ribonucleic Acid) is used as a detection target gene; and a detection probe of the ten common bacteria and a matched primer thereof are designed. A cellulose nitrate thin film strip is used as a substrate for fixing the probe and used for preparing a gene detecting film strip of the ten common bacteria. The 16SrRNA gene segment of the bacteria and a biotin mark are subjected to PCR (Polymerase Chain Reaction) amplification.After the PCR amplified segment is hybridized with the film strip, the biotin mark is detected by streptavidin marked by alkaline phosphatase and then an NBT (Nitroblue Tetrazolium)/BCIP (5-bromo-4-chloro-3'-indolyphosphate P-toluidine salt) color development is carried out. The result shows that the film strip can independently detect any one or more of the ten bacteria. The invention successfully researches the gene detecting film strip for the ten common bacteria and establishes a method for detecting bacteria by the film strip; and the method provided by the invention has the advantages of high throughput, high speed, accuracy and lower cost and has a good clinical application prospect.

The invention discloses a method for preparing borate by utilizing p-toluidine lithium. The method comprises the following steps: in a water-free and oxygen free environment and in an inert gas atmosphere, adding boron into a reaction bottle subjected to dehydration and deoxygenation treatment, then adding a catalyst (p-toluidine lithium), uniformly mixing, then adding ketone, carrying out hydroboration reaction, and carrying out termination reaction by being exposed to the air, so that borate is obtained, wherein the ketone is aromatic ketone or heterocyclic ketone. The invention firstly finds that p-toluidine lithium can catalyze the hydroboration reaction on the aromatic ketone or heterocyclic ketone and borane, and a new scheme is provided for preparation of borate by carrying out thehydroboration reaction on a carbonyl compound and borane.

The invention provides a preparation method of 1-hydroxy-4-(p-toluidino)anthraquinone. 1,4-dihydroxy anthraquinone, p-toluidine, ether solvents and a condensation catalyst are added to a reaction kettle, a system is gradually heated for a reaction, a product is filtered after the reaction ends, a filter cake is washed, dried and treated with a refining process, and a finished product, namely, 1-hydroxy-4-(p-toluidino)anthraquinone is obtained.

The invention discloses a 4-methyl-2-nitroaniline synthesis method, which comprises: carrying out amino protection with ethyl chloroformate by using 4-methylaniline as a raw material to generate N-(p-toluene)ethyl carbamate; adding an oxidant and a copper salt catalyst, and carrying out a reaction for a certain time at a temperature of 50-120 DEG C in a reaction solvent by using a nitroso-containing compound as a nitrating agent to prepare a corresponding protected o-nitro-p-toluidine; and carrying out hydrolysis to obtain the target product. According to the present invention, the method hasadvantages of simple preparation process, mild reaction condition, high yield and environment protection.

The invention relates to a cooked food packaging film and relates to the technical field of processing and production of a film. The cooked food packaging film is characterized by being prepared fromthe following materials in parts by weight: 14 to 20 parts of resin, 5 to 9 parts of calcium sulfate, 1 to 3 parts of polyhydroxyalkanoate, 4 to 9 parts of nano-silicon dioxide, 22 to 27 parts of hardened oil, 6 to 11 parts of p-toluidine, 9 to 13 parts of artemisia desterorum spreng gum, 60 to 68 parts of purple sweet potato starch, 7 to 12 parts of pullulan, 4 to 9 parts of sorbitol, 9 to 14 parts of an accelerant and 20 to 26 parts of biological aid. The method is reasonable and convenient in operation, the cooked food packaging film is easy to degrade, and damage to the environment is avoided.

The invention relates to the field of compound preparation and particularly relates to a novel crystal form of N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(3-(4-methyl-1,4-azaphosphine-1-yl)propyl-1-alkynyl)quinazoline-4-p-toluidine sulfonate as well as a preparation method and application of the novel crystal form. The novel crystal form of N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(3-(4-methyl-1,4-azaphosphine-1-yl)propyl-1-alkynyl)quinazoline-4-p-toluidine sulfonate having a better treating effect for excessive proliferative diseases is further obtained through crystallizing a mixed solvent prepared by mixing water and methanol, ethanol, n-propanol, isopropanol, acetone, acetonitrile, tetrahydrofuran or dioxane according to different proportions, so that not only is the pharmaceutical activity of the phosphorus-containing substituted quinazoline derivative improved, but also the bioavailability of the phosphorus-containing substituted quinazoline derivative is increased, and the blank for researching a drug with the crystal form of the phosphorus-containing substituted quinazoline derivative is made up.

The invention relates to an application of lithium p-toluidine, in particular to a method for preparing borate from aliphatic aldehyde. Borane is added to a reaction bottle subjected to dehydration and deoxidation treatment in a water-free and oxygen-free environment in an inert gas atmosphere, then, a lithium p-toluidine catalyst is added, the mixture is uniformly mixed, aldehyde is added, a hydroboration reaction is conducted, the reaction is ended by exposing the mixture to the air, and product borate is obtained. The aldehyde is selected from aliphatic aldehyde. It is found for the first time that lithium p-toluidine can extremely efficiently catalyze the hydroboration reaction of borane with cyclohexanecarboxaldehyde, propionaldehyde and n-heptaldehyde, and a new scheme is provided for preparing borate through the hydroboration reaction of a carbonyl compound and borane.

The invention relates to a method for preparing a compound methanol gasoline additive, which is characterized in that the compound methanol gasoline additive has hydrotropy, anti-rubber swelling property, oxidation resistance, metal corrosion resistance and combustion-supporting property. The additive comprises 10-55% of methyl tert-butyl ether, 0.05-10% of BTA, 15-60% of isopropyl alcohol, 0.03-25% of p-toluidine, 0.02%-12% of octadecylamine and 0.1-15% of 2,6 di-t-butyl-p-cresol. When the additive is used, firstly the prepared additive is mixed with methanol, and then mixed with a certain proportion of base gasoline uniformly to obtain methanol gasoline fuel. No ash is generated after the methanol gasoline prepared from the compound additive is combusted, and the emission of harmful substances in the exhaust can be greatly reduced. The additive has good low-temperature stability and dynamic performance, the normal operation of the engine system can not be affected on the premise of not changing the structure of the engine condition. The compound methanol gasoline additive has wide sources of raw materials, simple process and easy popularization.

This invention provides a cure promoter composition with suppressed solids forming tendencies. The composition is formed from components which prior to use in forming the composition are comprised of: a) N-methyl-N-(2-hydroxyethyl)-p-toluidine or N,N-bis(2-hydroxyethyl)-p-toluidine, or both; and b) at least one liquid monomeric ester of acrylic acid and/or at least one liquid monomeric ester of methacrylic acid; a) and b) being proportioned such that the a):b) weight ratio is in the range of about 50:50 to about 99:1.

A dual-cure curable material kit comprising: (A) a radical-polymerizable monomer component; (B) a photopolymerization initiator component comprising (b1) an α-diketone compound, (b2) an aliphatic tertiary amine compound having a tertiary amino group in which three saturated aliphatic groups are bonded to a nitrogen atom and one of the saturated aliphatic groups has an electron-withdrawing group as a substituent, and (b3) an s-triazine compound having a trihalomethyl group as a substituent, or a diaryliodonium salt compound; and a chemical polymerization initiator component (C) comprising (c1) an organic peroxide, and (c2) an N,N-di(hydroxyalkyl)-p-toluidine compound; which is packed separately at least in two packages so that the component (b2) and the component (b3) of the photopolymerization initiator component (B) are not packed together in a single package and the component (c1) and the component (c2) of the chemical polymerization initiator component (C) are not packed together in a single package.

A technology for synthesizing and purifying p-toluidine-3-sulfonic acid comprises the following steps: adding p-toluidine in concentrated sulfuric acid with the same amount, stirring to react for 2-5 hours at 210-220 DEG C, cooling, curing to obtain crude 4B acid; adding the crude 4B acid in water to stir, adding alkali to neutralize at 10-50 DEG C to ensure that the PH value of the neutralized solution is 7-9 and the 4B acid is completely dissolved; in 4B acid solution, adding activated carbon at 10-50 DEG C and stirring for 30-60 minutes to absorb impurities and decolor, filtering to obtain purified aqueous solution of 4B acid, wherein the content of activated carbon is 30-50wt% of the purified 4B acid; and adding acid in the discolored 4B acid under stirring to ensure that the pH value is 1-2 and white crystals are precipitated, filtering, and washing with water to obtain high purity 4B acid. The method has the advantages of easy method, low cost and high product purity.

The invention relates measuring method of monoamine oxidase activity and its diagnostic kit, comprising the following steps: using the benzylamine, p-toluidine red-ª‰-azo naphthol, butyl amine, amyl amine, ª‰-phenylethylamine, tyramine and other aminated compounds as substrate, it reacted with monoamine oxidase to produce auricome, then auricome carried out coupling reaction with hydrogen peroxidase and aldehyde dehydrogenase, carrying out the reaction to turn the oxidation type coenzyme to reduction type coenzyme, detecting the ascending velocity of absorbance of main wavelength 340nm to reflect the activity of monoamine oxidase in sample by definite quantity. The method has high specificity, good accuracy. The diagnostic kit is made to double agents or tri-agent to reduce the across impact and keep the agent stability and be good for long term storage. The method can be rapidly detected by the ultra-violet/visible light analysis meter or semi-automatic/full-automatic biochemical analysis meter, so the method is easy to spread and use.

The invention relates to a medical denture material and its molding technology. The molding technology comprises the following steps: mixing 30-40 parts by weight of a urethane dimethacrylate matrix, 2-3 parts by weight of 1,6-ethylene glycol dimethacrylate, 1-2 parts by weight of N,N'-dihydroxyethyl-p-toluidine, 1-2 parts by weight of 2,6-di-tert-butyl-p-cresol, 0.5-1 part by weight of benzoyl peroxide, 1-2 parts by weight of camphorquinone, 1-2 parts by weight of dimethylamino neopentyl glycol acrylate, 1-2 parts by weight of metacrylic acid ester, 40-45 parts by weight of a fumed silica excipient, 0.1-0.2 part by weight of a shrinkage control copolymer powder, 0.2-0.3 parts by weight of a silane coupling agent and 0.3-0.5 part by weight of synthetic fibre, uniformly stirring, and vibrating to remove bubbles; coating a mixture obtained with a layer of a surface air-isolating agent composed of water-soluble matrigel and sodium sulfite or sorbitol, and carrying out photopolymerization; letting conversion rate reach 70% after 5 minutes of photopolymerization and letting conversion rate reach 95% and above after 24 hours of photopolymerization; and washing with cold water. The material of the invention has excellent performance, Brinell hardness and friction wear ability and has good biocompatibility.

The invention belongs to the technical field of solvent pigment 5B green, and particularly relates to solvent pigment 5B green and a preparation method thereof. The solvent pigment 5B green is prepared from the following raw materials in parts by weight: 35 to 48 parts of 1,4-dihydroxy anthraquinone; 24 to 32 parts of p-toluidine; 1-3 parts of boric acid; and 1-3 parts of hydrochloric acid, wherein the mass fraction of the hydrochloric acid is 27%-35%. The preparation method of the solvent pigment 5B green comprises the following steps: firstly, carrying out a condensation reaction on the 1,4-dihydroxy anthraquinone and the p-toluidine to prepare the solvent pigment 5B green, and carrying out primary filter pressing, refining, secondary filter pressing and drying on the solvent pigment 5Bgreen to prepare the solvent pigment 5B green. The solvent pigment 5B green has the advantages of good heat resistance, good light-resistant stability, good migration resistance and good coloring performance; tests show that the heat resistance of the solvent pigment 5B green in PS reaches 310 DEG C, the light fastness of the solvent pigment 5B green in PS can reach the 7-8 level, the migration resistance reaches the 4-5 level, and the tinting strength is larger than or equal to 99.8%.