155results about How to "Simplified separation steps" patented technology

The invention discloses a method and a device for co-preparing di(C1-3) alkyl carbonate and di(C1-3) alkyl oxalate. The method comprises the following steps of: a) separating a product of a di(C1-3) alkyl carbonate synthesis reactor into a first liquid phase and a first gas phase; b) separating a product of a di(C1-3) alkyl oxalate synthesis reactor into a second liquid phase and a second gas phase; c) conveying the first liquid phase to a first rectifying tower from the tower top, conveying the combined first gas phase and second gas phase to the first rectifying tower from the middle lower part of the tower, conveying the second liquid phase to the first rectifying tower from the tower bottom, and generating basically pure di(C1-3) alkyl oxalate fraction from the bottom of the first rectifying tower during rectifying; d) separating the overhead fraction produced in the first rectifying tower into a third liquid phase and a third gas phase; and e) conveying the third liquid phase to a second rectifying tower from the middle part of the tower, and generating basically pure di(C1-3) alkyl carbonate from the bottom of the second rectifying tower. Only three rectifying towers are designed in the whole process through reasonable process design, so the energy requirement and operation expense are effectively reduced, and the equipment investment expense is saved.

The invention provides a pretreatment method of detection on malachite green, crystal violet and residues of malachite green and crystal violet in eels, belonging to the field of analytical chemistry. The method comprises the operations of weighing of a sample to be detected, homogenization, solid phase extraction, elution and the like; instruments used in the method comprise a constant temperature oscillator, a high speed dispersing homogenizer, a centrifugal machine and the like. A sample solution prepared by using the pretreatment method can be directly detected by using a liquid chromatogram-tandem mass spectrometry method; compared with the prior art, the pretreatment method has the advantages of simple and effective operation, less time consumption, low cost, good reproducibility and the like, and has very strong operability, so that the pretreatment method has the hope to be widely popularized and applied in a large scale in industries such as environment protection, commodity inspection, entry and exit inspection and quarantine and the like, with significant economic benefits.

The invention discloses an extraction device of a plant active ingredient. The device comprises a homogenate equipment tank body (1) and an end cover arranged at the upper end, wherein the end cover (13) and the homogenate equipment tank body (1) are sealed through a C-shaped clamp and a gasket; a feed funnel (12), an anchor agitator (6), a high-speed shearing agitator (9) and an ultrasonic generator (8) are mounted on the end cover (13); an agitating paddle of the anchor agitator (6), the high-speed shearing agitator (9) and a probe (10) of the ultrasonic generator all extend into a working cavity of the homogenate equipment tank body (1) from the end cover (13); the anchor agitator (6) comprises a motor (7) providing power, a rotation shaft and an agitating paddle; the high-speed shearing agitator (9) and the probe (10) of the ultrasonic generator are located between the agitating paddle and the rotation shaft; and a detachable blade (11) is mounted on the rotation shaft. The device disclosed by the invention has a simple structure and is easy to clean; and the working efficiency is high, and the operation range is wide.

The invention discloses an antibody conjugated medicine and a preparation method and application thereof. The antibody conjugated medicine is formed by connecting an antibody and a medicine through a connecting arm. The antibody is an anti-CD20 monoclonal antibody with heavy chain containing LPXTG sequence. The medicine is aplysiatoxin or a derivative thereof. The connecting arm contains a short-peptide linker for connecting the antibody and a self-elimination linker for connecting the medicine. The short-peptide linker contains at least 1-3 continuous glycines. The antibody conjugated medicine has high uniformity and can achieve higher in-vitro and in-vivo antineoplastic activity with less drug loading capacity (DAR) than CD20 targeting ADC prepared by other chemical methods. IC50 (median inhibitory concentration) for Ramos cells can reach 0.005 nanogram/milliliter.

The present invention relates to a method for separating ammonia carbon in melamine tail gas. The method is characterized by comprising absorption, distillation, rectification, decarbonization and other steps. The method has the following advantages that: the low pressure steam produced by the triamine urine washing tower is utilized at a maximum, and the heat of the urine washing tower is recovered by adopting the forced circulation way so as to reduce the steam consumption during the separation process; and the separated water is adopted to replace the desalted water and is supplemented into the urine washing tower steam chest so as to be recycled, such that the apparatus achieves no wastewater discharge so as to provide characteristics of water saving and environment protecting.

The invention discloses plant effective component extraction equipment for medical material preparation. An ultrafine grinding mechanism is arranged in a mounting case, and an effective component extraction mechanism is arranged on the lower portion of the ultrafine grinding mechanism and comprises a leacher and an efficient cleaning device. The leacher comprises a leaching vessel, the bottom of the leaching vessel is connected with a dry powder guide pipe and a water pulp guide pipe through pipes, and the upper portion of the leaching vessel is connected with a leach liquid adding box which is connected with a filling pipe. The efficient cleaning device comprises an ultrasonic wave generator, an ultrasonic transducer and an ultrasonic amplification rod. An output end of the ultrasonic wave generator is electrically connected with an input end of the ultrasonic transducer, an output end of the ultrasonic transducer is electrically connected with an electric energy input end of the ultrasonic amplification rod, and the ultrasonic amplification rod penetrates the lower bottom surface of the leaching vessel to extend into the leaching vessel. The plant effective component extraction equipment has advantages that separation of impurities and effective components in to-be-extracted plants is realized, and the step of subsequent separation of the effective components in the to-be-extracted plants is simplified.

The invention discloses a harmless treatment method for dead animal bodies, and relates to the technical field of animal harmless treatment. The harmless treatment method comprises the following steps of: conveying the dead animal bodies into a crushing and stirring device to crush; in a crushing process, starting a heating device on the bottom of the crushing and stirring device, heating and drying the dead animal bodies; when a heating temperature reaches a preset value, smelting out oil in the dead animal bodies; discharging grease and residues generated after dead animal body smelting into a spiral conveying device; and in a conveying process of the spiral conveying device, realizing separation of grease and residues. The harmless treatment method disclosed by the invention is relatively low in cost; and the residues subjected to harmless treatment can be used for preparing products capable of being recycled, so that a resource utilization rate is increased.

The invention relates to application of a microorganism material in detection of environmental pollutants, in particular to a fluorescent iron carrier secreted by pseudomonas aeruginosa (Pseudomonas aeruginosa) PA1 and application thereof. The pseudomonas aeruginosa PA1 is registered and preserved in China General Microbiological Culture Collection Center (CGMCC); the preservation date is April, 28th, 2011; and the number is CGMCC No.4799. When the fluorescent iron carrier secreted by pseudomonas aeruginosa (Pseudomonas aeruginosa)PA1, related by the invention, is used for detecting furazolidone in the environment, the fluorescent iron carrier has the advantages of high specificity and fastness, and the furazolidone is quickly and sensitively detected on the basis of optimization of experimental conditions.

The invention provides a magnetic organic solid base catalyst. Magnetic nanospheres with a uniform particle size are prepared by miniemulsion polymerization, and an organic base is supported on the microspheres to obtain the novel magnetic organic solid base catalyst. The method provided by the invention avoids the problem of loss of active sites of a conventional supported catalyst, maintains high efficiency of the catalyst, and effectively prolongs service life of the catalyst; at the same time, separation of the catalyst and a reaction system can be realized under an external magnetic field, and a separation step of the catalyst is greatly simplified; the magnetic organic solid base catalyst can be applied to a transesterification, esterification or aldol condensation reaction; and thepreparation method provided by the invention is simple, and the prepared catalyst has the characteristics of having high efficiency, saving energy, and being non-toxic, easy to separate and recyclable.

The invention belongs to the technical field of a synthesis compound, and provides a sulfoacid resin catalyst and a method for continuously producing (methyl) hydroxyethyl acrylate and (methyl) diester acrylate. The continuous production method comprises the following steps of (1) contacting dihydric alcohol, (methyl) methyl acrylate and polymerization inhibitors to form reaction liquid; continuously injecting the materials into a reaction device containing the sulfoacid resin catalyst for reaction so as to obtain coarse reaction liquid; (2) injecting the coarse reaction liquid obtained in thestep (1) into a phase splitting tank; performing double-solvent extraction; respectively obtaining a water phase containing (methyl) hydroxyethyl acrylate and an oil phase containing (methyl) diesteracrylate; (3) respectively performing rectification on the water phase and the oil phase in the step (2) to obtain (methyl) hydroxyethyl acrylate and (methyl) diester acrylate products. The method has the advantages that the product separation step is simplified; the separation temperature is low and the product purity is high.

The invention discloses a method for separating ovalbumin from egg white. The method comprises 1) taking fresh eggs and collecting an egg white stock solution, 2) adding a dilution buffer into the solution to obtain an egg white diluent A, 3) adding octanoic acid into the egg white diluent A and carrying out standing to obtain an egg white diluent B, 4) adding hydrophobic charge-induced agnetic beads into the egg white diluent B and carrying out shaking to adsorb ovalbumin, 5) washing the beads with the dilution buffer multiple times to obtain the hydrophobic charge-induced magnetic beads adsorbing the ovalbumin, 6) adding an elution buffer into the magnetic beads, carrying out shaking and collecting an ovalbumin solution, and 7) carrying out freeze-drying to obtain an ovalbumin solid product having purity greater than 98%. The method designs a simple and fast separation process, realizes separation of ovalbumin from egg white, is characterized by directly separating ovalbumin from egg white and has the advantages of simple operation processes and high separation efficiency.

The invention relates to preparation and applications of a magnetic composite porous network adsorbing material, wherein the preparation method comprises: (a) preparing a magnetic porous organic framework material with strong adsorbability and large specific surface area by adopting an in-situ growth method, and (b) synthesizing a novel composite porous network adsorbing material with a core-shellstructure through a sonogashira coupling reaction so as to achieve the selective adsorption and efficient enrichment of food and environment pollutants. According to the present invention, the prepared magnetic composite porous network adsorbing material has good particle size uniformity and significantly efficient adsorption capacity on target pollutants, the separation step during solid-phase extraction is greatly simplified due to the magnetic characteristic of the material, and the microporous organic coating changes the hydrophobicity of the surface of the material, such that the material has high stability in a humid environment, can well play a role in an organic solvent, and is suitable for adsorption and enrichment of various food pollutants.

The invention discloses a method for separating immune globulin IgY(delta Fc) from goose blood. The method comprises the following steps: 1) degreased plasm preparation, wherein fresh blood is selected to be centrifuged to remove erythrocyte, and then is degreased to obtain the degreased plasm; 2) octanoic acid precipitate, wherein octanoic acid is added to the plasm to reach a certain concentration, hybrid protein is precipitated and removed, and is centrifugally separated to obtain supernate; 3) column chromatography, wherein the supernate is separated by a chromatographic column which is filled with hybrid mode adsorbent to collect elution peak; and 4) desalination and drying, wherein the collected fluid is desalinated, refrigerated and dried to obtain the immune globulin IgY(delta Fc) with purity of over 95 percent. The method is characterized in that a new separation process is designed, the immune globulin IgY (delta Fc) can be separated from the goose blood; and the key of the method is that the immune globulin IgY (detal Fc) can be directly extracted from the supernate which is precipitated from the octanoic acid. The method has the advantages of simple operation steps and high separation and purification factors, and can be popularized and applied to treatment of blood of other waterfowls.

The invention discloses a method for extracting magnolol and honokiol from magnolia officinalis; the method includes that: magnolia officinalis powder and solid phase weak base reagent are mixed according to the weight ratio of 1:0.01-1, the mixture is grinded to obtain powder with granularity analysis result D90 of 10-200 um, and then water is added to the powder, the mixture is stirred sufficiently and is centrifuged to obtain sediment A and supernate A, acid X with pH value of 1.0-6.0 is added to the supernate A, then the supernate is centrifuged after standing to obtain sediment B as magnolol extractive. The invention firstly adopts mechanical chemical reaction technique to extract magnolol, and then adopts alkaline process to extract honokiol, has the advantages of high extraction rate, good separation effect of magnolol and honokiol, and short production cycle, and is the extraction and separation process with good popularization and application prospect.