The invention provides a therapeutic drug for treating uterine fibroid, adenomyosis, cervical polyp and human papillomavirus (HPV). The drug comprises the following components: 10-20 parts of herba boschniakia rossica, 5-10 parts of lucid ganoderma, 5-10 parts of alumen, 5-10 parts of wild ginseng, 10-20 parts of semen persicae, 10-20 parts of saffron, 10-20 parts of motherwort herb, 10-15 parts of borneol, and 5-10 parts of radix sophorae flavescentis. The drug has inhbiting effects on staphylococcus aureus, escherichia coli, candida albicans and human papillomavirus, and can be used for inhibiting and resisting microbes and daily bacteriostatic nursing of cleaning gynecological wastes in the treatment of uterine fibroid, adenomyosis, cervical polyp, human papillomavirus. The invention also provides a technological process for the therapeutic drug for treating uterine fibroid, adenomyosis, cervical polyp and human papillomavirus, and the process comprises selecting the raw materials,pretreating the raw materials, drying, pulverizing, bagging, packaging and warehousing, and the technological process is simple in operation, the raw materials are simple and easy to obtain, the costis low and the process is worth promoting.