The invention discloses bio-antibacterial body wash. The bio-antibacterial body wash comprises raw materials in parts by weight as follows: 3-8 parts of water extraction fermentation broth of tea saponin, 4-10 parts of water extraction fermentation broth of Chinese soapberry fruit, 5-9 parts of octenyl succinate glucose ester, 0.3-0.5 parts of hydrogenated castor oil, 10-15 parts of goat whey enzymatic hydrolysate, 5-10 parts of nano-degraded chitosan, 0.05-0.1 parts of sodium polyaspartate, 0.2-0.6 parts of anhydrous citric acid, 4-12 parts of medical stone powder, 3-6 parts of inactivated probiotics and 42-75 parts of deionized water. The bio-antibacterial body wash is prepared with a simple method, contains non-toxic or extremely low-toxic components, is non-irritant to skin, safe to use and low-residue, cannot threaten health, has light tea oil aroma, can adsorb dirt and grease in deep layer of the skin and clean the skin sufficiently on one hand, and has the effects of moisturizing, whitening, aging delaying, inflammation diminishing, repairing, bacterial resisting and the like on the other hand.