The invention discloses a sterilizing protective brush for a shopping mall escalator, and relates to related technical field of elevator materials. The sterilizing protective brush for the shopping mall escalator disclosed by the invention is prepared from the following components: acrylic resin, Hu mulberry powder, turpentine, paraffin, trisodium phosphate, ethyl alcohol, deionized water, propylene bituminous resin, alkali solution, polycarbonate, broussonetia papyrifera bark powder, sandalwood bark powder, reed straw powder, an adhesive, a stabilizing agent, carbohydrase, blood enzyme, an active auxiliary agent, polyethylene wax, carboxymethyl cellulose, pyridine butadiene rubber, an anti-aging agent, camphor, staphylococcus aureus-dissolving enzyme, superoxide dismutase, lysozyme, matrigel, and 0.1 mol/l phosphate buffer solution. The sterilizing protective brush disclosed by the invention achieves a protecting effect when an escalator is used, can also inhibit the production of bacteria, and can purify the environment; moreover, the sterilizing protective brush has high efficiency, impact resistance, environment friendliness, toughness, bacterium removing property, and fatigueresistance.