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34 results about "Guanidine hcl" patented technology

Guanidine HCl is a freely soluble chaotropic agent routinely used for protein denaturation and folding.

Method for preparing uramine-type macromolecule anti-bacterial agent

The invention relates to a method for preparing an uramine-type macromolecule anti-bacterial agent, comprising two steps as follows: A, mixing any one solution of guanidine hcl, Polyhexamethyleneguanidine chloride and polyhexamethylene biguanide hydrochloride with maleic anhydride solution; introducing nitrogen for constant-temperature water bath reaction to obtain functional uramine salt; B, mixing functional uramine salt solution with acrylamide and / or styrene for constant-temperature water bath reaction to obtain ivory-white stringy liquid; depositing soft white solid with solvent for vacuum drying to obtain ivory-white bulk uramine-type copolymer, i.e, uramine-type macromolecule anti-bacterial agent. The uramine-type macromolecule anti-bacterial agent has remarkable effect and simple synthesis process, ensures that the anti-bacterial group is hard to move and the processing thermal stability is excellent through copolymerization on macromolecule long chain. The invention can be widely used in fields of plastic, dope, powder dope, rubber, wood plastic, rubber plastic, spinning, water processing, and the like.
Owner:安徽合汇金源科技有限公司

Chitosan biguanide hydrochloride, preparation method and use thereof

InactiveCN101033264AStrong and broad-spectrum antibacterial activityRich sourcesBiocideDisinfectantsSolubilitySide effect
The invention provides a new chitosan derivate-chitosan biguanide muriate, its preparation and usage, in which, the repeat unit is 2-biguanide glucose muriate, the substitution degree of guanidine is 15-50%, and the molecular weight is 0.5-25 ten thousand. This invention uses the reaction of chitosan and dicyandiamide to prepare chitosan biguanide muriate, and has advantages of mild reaction conditions and fewer side effects. The product has good antibacterial activity and water solubility, and can be widely used in medicine, textile industry, agriculture and other fields.
Owner:WUHAN UNIV

Method for producing adipic acid, hexamethylenediamine hydrochloride and polyhexamethylene (di)guanidine chloride from nylon-66 through depolymerization

The invention discloses a method for producing adipic acid, hexamethylenediamine hydrochloride and polyhexamethylene (di)guanidine chloride from waste nylon-66 serving as a raw amerial through depolymerization, which is characterized by comprising the following steps of: depolymerizing the waste nylon-66 by using hydrochloric acid to obtain refined adipic acid and hexamethylenediamine hydrochloride; polymerizing the hexamethylenediamine hydrochloride and dicyandiamide (in a molar ratio of 1:1) at the temperature of between 170 and 190DEG C for 1 to 3 hours to obtain a white or pale yellow solid polyhexamethylene diguanidine chloride; and adding dicyandiamide and ammonium chloride powder in a molar ratio of 1:2 into a reactor, performing reaction at high temperature for 1 to 3 hours, slowly adding hexamethylenediamine hydrochloride powder, continuously reacting for 3 to 7 hours to obtain a white or pale yellow solid polyhexamethylene guanidine chloride. The method improves production efficiency, reduces production cost, and solves the problems of difficult separation of the product hexamethylenediamine due to depolymerization, low yield and poor benefit; and the technological process is environment-friendly, simple and convenient, and is suitable for industrial production.
Owner:NINGBO UNIV

Novel organophosphorus flame retardant and preparation method thereof

The invention discloses a novel organophosphorus flame retardant and a preparation method thereof, and the preparation method comprises the following steps: by taking 2-amino-4,6-dichloropyrimidine, allylamine, DOPO, a bifunctional epoxy compound and 1-aminohexyl guanidine hydrochloride as raw materials, carrying out substitution, addition, epoxy ring opening and other multi-step reactions to obtain a novel organophosphorus flame retardant material. The novel flame retardant not only effectively solves the problems that an existing common flame retardant has poor flame retardant effect, needs to be added in quantity and has single function, but also has efficient broad-spectrum antibacterial property, and does not influence the mechanical property of the final material. The material is particularly suitable for the fields of indoor decoration materials such as non-woven fabrics and synthetic leather, and is wide in application range.
Owner:东莞市道尔新材料科技有限公司

Preparation method of antibacterial super absorbent resin

The invention provides a preparation method of antibacterial super absorbent resin. The preparation method comprises the following steps: under stirring conditions, atomizing and dispersing an antibacterial agent aqueous dispersion on the surfaces of super absorbent resin beads to obtain antibacterial super absorbent resin, wherein an antibacterial agent in the antibacterial agent aqueous dispersion is selected from one or more of chitosan, aloe freeze-dried powder, polyhexamethylene guanidine hydrochloride, nano-silver, nano-zinc oxide and quaternary ammonium salt; and the super absorbent resin beads are selected from partially hydrolyzed polyacrylamide and / or sodium polyacrylate. The partially hydrolyzed polyacrylamide and / or sodium polyacrylate are / is used as a super absorbent resin matrix, and the antibacterial super absorbent resin with excellent antibacterial performance is prepared by combining the super absorbent resin beads and the antibacterial agent, combining the super absorbent characteristics of the super absorbent resin beads, and utilizing the adsorption effect of the super absorbent resin on a water phase system through a simple mixing adsorption process to realizeadsorption compounding of the antibacterial agent in the super absorbent resin beads. The antibacterial rate of the antibacterial super absorbent resin on escherichia coli and staphylococcus aureus is up to 99%.
Owner:CHANGCHUN INST OF APPLIED CHEMISTRY - CHINESE ACAD OF SCI +2

Application of vanillin crosslinked chitosan oligosaccharide mono guanidine hydrochloride in preparation of anti-oxidation drugs

The invention discloses application of vanillin crosslinked chitosan oligosaccharide mono guanidine hydrochloride in preparation of anti-oxidation drugs. The application of the vanillin crosslinked chitosan oligosaccharide mono guanidine hydrochloride in the preparation of the anti-oxidation drugs comprises the following steps: taking a chitosan oligosaccharide product as a raw material, oxidizingunder double effects of hydrogen peroxide and concentrated sulfuric acid to obtain thiourea trioxide as a guanidination reagent, taking vanillyl alcohol as a crosslinking agent, carrying out liquid-phase synthetic reaction under a microwave condition to obtain a vanillin crosslinked chitosan oligosaccharide hydrochloride derivative with a mono guanidine group, repeatedly washing the vanillin crosslinked chitosan oligosaccharide hydrochloride derivative with the mono guanidine group to be neutral by using ethanol, and finally placing solid in a vacuum dryer and drying at the temperature of 40-80 DEG C until the water content of the material is smaller than 0.5%-10%. The method has the advantages of simplicity and easiness, less side reaction and the like, meanwhile, guanidyl and a crosslinked structure are introduced into chitosan oligosaccharide with good biological compatibility, thus, the bioactivity, stability and solubleness of the chitosan oligosaccharide are remarkably improved,and application in preparation of the anti-oxidation drugs is shown.
Owner:TIANJIN UNIV

Methods of protein purification and recovery

Improved methods for purification and recovery of interferon-beta (IFN-β) and compositions comprising substantially monomeric IFN-β are provided. In one purification method, substantially purified IFN-β or variant thereof is precipitated and then dissolved in a guanidine hydrochloride (HCl) solution. Renaturation of the protein occurs by dilution with a suitable buffer. A similar purification method absent the precipitation step is also provided. Following renaturation of the IFN-β residual guanidine HCl is removed by diafiltration or dialysis with a pharmaceutically acceptable buffer to prepare pharmaceutical compositions comprising substantially monomeric IFN-β.
Owner:NOVARTIS VACCINES & DIAGNOSTICS INC

Long-acting disinfectant stabilized by synergistic agent

The present invention provides a long-acting disinfectant stabilized by a synergistic agent. The synergistic agent mainly comprises polyethylene glycol long-chain alkylamine, benzalkonium chloride, polyhexamethylene guanidine hydrochloride, quaternary ammonium salt-73 and the like. The benzalkonium chloride, polyhexamethylene guanidine hydrochloride and quaternary ammonium salt-73 have bactericidal ability and can react with chlorine dioxide to disperse charges on oxygen atoms of chlorine dioxide, so that the stabilizing effect on chlorine dioxide is achieved. The polyethylene glycol long-chain alkylamine can effectively wrap chlorine dioxide, benzalkonium chloride, polyhexamethylene guanidine hydrochloride, quaternary ammonium salt-73 and other active ingredients through the coordinationeffect of a plurality of oxygen atoms of the polyethylene glycol long-chain alkylamine, and long-chain alkyl fragments have an isolation effect, so that the degradation speed of the active ingredientsis reduced, and long-acting disinfection is realized.
Owner:SHANGHAI COACHCHEM TECH

Co-extrusion type base-coat-free matt film with antibacterial function and preparation method of co-extrusion type base-coat-free matt film

The invention discloses a co-extrusion type base-coat-free matt film and a preparation method thereof, belonging to the technical field of pre-coated film composites. The film comprises a film body, wherein the film body sequentially comprises an antibacterial agent layer, a matt layer, an antistatic layer, a supporting layer, an adhesive layer and an anti-adhesion agent layer from top to bottom; antibacterial components of the antibacterial agent layer comprise one or more selected from a group consisting of graphene and derivatives thereof, sodium hypochlorite, nano-silver, cuprous oxide, zinc oxide, polyhexamethylene biguanide hydrochloride, polyhexamethylene guanidine hydrochloride, polyhexamethylene guanidine phosphate, organosilicon quaternary ammonium salt and a peony root bark extract. The co-extrusion type base-coat-free matt film with the antibacterial function has good antibacterial property and anti-pollution capacity.
Owner:山东顺凯复合材料有限公司

A high-efficiency compound guanidine-based fungicide for papermaking

ActiveCN110074105BImprove effective activityInhibition of mitotic functionBiocideFungicidesBiotechnologyCellulose
The invention provides a high-efficiency composite guanidine-based paper-making fungicide, which belongs to the technical field of paper-making fungicide production. In parts by weight, the fungicide comprises the following components: 10-30 parts of guanidine-based polymer, N-octyl 5-15 parts of isothiazolinone, 150-450 parts of diethylene glycol, 0.5-1.5 parts of dodecyl dimethyl benzyl ammonium chloride, 0.3-1.8 parts of hydroxymethyl cellulose, o-phenyl Potassium hydrogen diformate 0‑100 parts. The guanidine-based polymer is polyhexamethylene biguanide hydrochloride. Polyhexamethylene biguanide hydrochloride is broad-spectrum antibacterial, has killing ability to Gram-positive bacteria, Gram-negative bacteria, fungi and yeast, and can be used to produce antibacterial paper for health and hygiene products to replace silver-containing libraries At the same time, the polyhexamethylene biguanide hydrochloride solution also improves the physical properties of the paper, water absorption, strength after being wetted with water, and air permeability, so it is a papermaking fungicide with excellent performance. The synergistic effect is a compound TS-302 papermaking fungicide with high efficiency and broad spectrum.
Owner:甘肃泰升化工科技有限公司

Concentrated long-acting antibacterial and anti-fouling PC master batch and preparation method thereof

The invention belongs to the technical field of plastic master batches, and particularly relates to a concentrated long-acting antibacterial and anti-fouling PC master batch and a preparation method thereof. The concentrated long-acting antibacterial and anti-fouling PC master batch comprises the following raw materials in parts by weight: 30-100 parts of polycarbonate and 1-20 parts of an antibacterial agent. The antibacterial agent is prepared from the following raw materials in parts by weight: 10-35 parts of a cationic polymer, 30-80 parts of a compatilizer and 20-50 parts of organic amine. The cationic polymer is guanidine salt, and the compatilizer is selected from maleic anhydride copolymer. The maleic anhydride copolymer and polyhexamethylene biguanide hydrochloride react to generate chemical bonding between the polyhexamethylene biguanide hydrochloride and the maleic anhydride copolymer, the compatibility of the polyhexamethylene biguanide hydrochloride and the polycarbonate is improved, moreover, the inventor finds that polyhexamethylene biguanide hydrochloride cannot be separated out on the surface of polycarbonate and cannot be separated from polycarbonate, and by adding organic amine, chemical bonding is generated between the organic amine and the maleic anhydride copolymer, and the compatibility and mechanical properties of the whole material can be further improved.
Owner:EAST CHINA UNIV OF SCI & TECH

Preparation method of guanidine hydrochloride antibacterial agent modified maleic anhydride grafted co-polypropylene composite material

The invention discloses a preparation method of a guanidine hydrochloride antibacterial agent modified maleic anhydride grafted polypropylene random copolymer composite material, which is characterized by comprising the following steps: adding 1,6-hexamethylenediamine into a liquid dispersion medium, and adding hydrochloric acid, a guanidine derivative and a carboxylic acid solution to obtain a guanidine hydrochloride antibacterial agent; swelling polypropylene random copolymer and a grafting aid, adding maleic anhydride, an antioxidant, a beta-nucleating agent and an initiator, and sequentially mixing, melting and granulating to obtain maleic anhydride grafted polypropylene random copolymer; and mixing the two substances with an organic solvent and a catalyst, and then carrying out melt extrusion and granulation. According to the antibacterial polypropylene random copolymer, the dispersity of PDMG in polypropylene random copolymer can be effectively improved, the antibacterial agent can stably exist in a PPR matrix, and the antibacterial effect is better and more stable; the molecular structure of the prepared composite material contains guanidyl and hydroxyl, so that the composite material has good hydrophilicity, no toxicity, stronger surface activity and permanent antibacterial activity.
Owner:SHANGHAI INST OF TECH

Reusable breathable antibacterial electrode plate and preparation method thereof

The invention discloses a reusable breathable antibacterial electrode plate and a preparation method thereof. The reusable breathable antibacterial electrode plate comprises an electrode plate body and a conductive film, the conductive film is sequentially composed of a hydrogel layer, a silver layer and a hydrocolloid layer from bottom to top, and the electrode plate body and the hydrocolloid layer are tightly bonded, the hydrogel layer is prepared from the following raw materials: eugenol, boron trifluoride diethyl etherate, triisopropylsilane, lipidosome, multi-walled carbon nanotubes, polydiallyldimethylammonium chloride, nanocellulose, polyacrylamide, ammonium persulfate, methacrylic anhydride, polyhexamethylene guanidine hydrochloride, octylphenol polyoxyethylene ether, Tween-80, anhydrous trifluoroacetic acid or boron trifluoride. According to the electrode plate, the composite conductive hydrogel is used as a conductive film, so that the electrode plate is good in conductivityand biological safety, and still has self-adhesion, air permeability, sweat absorbability and antibacterial property under the action of sweat, slight deformation can be achieved according to human skin elasticity, and electric signal stability is not affected, and the electrode plate is convenient to remove and can be repeatedly used.
Owner:THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV

Antibacterial transparent material, preparation method thereof, water storage container and dish washing machine

The invention relates to the field of high polymer materials, and provides an antibacterial transparent material, a preparation method thereof, a water storage container and a dish-washing machine. Raw materials of the antibacterial transparent material comprise transparent plastic particles and an antibacterial agent, and the antibacterial agent is one or more of polyhexamethylene guanidine hydrochloride, polyhexamethylene biguanide hydrochloride, isothiazolinone and a quaternary ammonium salt antibacterial agent. According to the invention, specific types of antibacterial agents, specifically at least one of polyhexamethyleneguanidine hydrochloride, polyhexamethylenebiguanide hydrochloride, isothiazolinone and quaternary ammonium salt antibacterial agents, are selected, so that the long-acting antibacterial effect is realized, and the light transmittance of the original transparent plastic particles is hardly reduced.
Owner:FOSHAN SHUNDE MIDEA WASHING APPLIANCES MFG CO LTD

Antibacterial coating liquid as well as preparation method and application thereof

The invention belongs to the technical field of antibacterial coating preparation, and particularly relates to antibacterial coating liquid as well as a preparation method and application thereof. The antibacterial coating liquid is prepared from the following raw materials: an organic antibacterial agent, an inorganic antibacterial agent, alcohol ester-12, emulsified methyl silicone oil, allyl-3-methylimidazolium chloride, silicone acrylic emulsion and water; wherein the organic antibacterial agent is a mixture of N-[(2-hydroxy-3-trimethylamine) propyl] chitosan chloride, polyhexamethylene guanidine hydrochloride, dodecyl guanidine monohydrochloride, isothiazolinone and salicylanilide; and the inorganic antibacterial agent is a mixture of modified nano zinc oxide and nano cerium oxide. According to the antibacterial coating liquid disclosed by the invention, the organic antibacterial agent and the inorganic antibacterial agent are added into the silicone acrylic emulsion, and the organic antibacterial agent and the inorganic antibacterial agent are compounded for use, so that the prepared antibacterial coating liquid is remarkable in antibacterial effect, lasting in effect, stable in performance and low in toxicity, and the application range is widened.
Owner:山东晶承净化科技有限公司

Polyhexamethylene guanidine silver ion composite disinfectant

PendingCN113940357AReduce the concentration of silver ionsImprove the bactericidal effectBiocideFungicidesAntichlorPolyhexamethylene guanidine
The invention relates to a polyhexamethylene guanidine silver ion composite disinfectant, which comprises a water-soluble silver salt, polyhexamethylene guanidine hydrochloride and an anti-tarnish factor, wherein in the composite disinfectant, the concentration of the water-soluble silver salt is 5 mg / L to 50 mg / L, the concentration of the polyhexamethylene guanidine hydrochloride is 0.5 g / L to 5 g / L, the concentration of the anti-tarnish factor is 100 mg / L to 500 mg / L, and the anti-tarnish factor comprises a water-soluble amine compound. According to the polyhexamethylene guanidine silver ion composite disinfectant, the concentration of silver ions is reduced while an excellent sterilization effect can be achieved, and the polyhexamethylene guanidine silver ion composite disinfectant has good discoloration resistance, including non-discoloration at high temperature, non-discoloration under sunlight exposure, chlorine resistance and the like.
Owner:NUOVO FILM SUZHOU CHINA INC

Cold compress gel as well as use method and application thereof

The invention discloses cold compress gel as well as a use method and application thereof. The cold compress gel is prepared from hydroxypropyl methyl cellulose, carbomer, sodium hyaluronate, glycerol, ceramide, a cooling agent, eucalyptus oil, glycyrrhetinic acid, sodium gualenate, turpentine, poloxamer, collagen, polyethylene glycol, octenidine hydrochloride, polyhexamethylene biguanide hydrochloride and water. According to the cold compress gel as well as the use method and application thereof, the cold compress gel can be used for physical fever abatement, detumescence, itching relieving and the like of a human body, can also be used for shrinking pores, and is wide in applicable crowd.
Owner:SHENZHEN CHANGER MEDICAL TECH CO LTD

Application of polyhexamethylene guanidine in citrus sour rot prevention and treatment, and citrus antistaling agent containing polyhexamethylene guanidine

The invention discloses application of polyhexamethylene guanidine in citrus sour rot prevention and treatment, and a citrus antistaling agent containing polyhexamethylene guanidine. The citrus antistaling agent containing polyhexamethylene guanidine comprises: by mass, 0.05 to 0.6% of polyhexamethylene guanidine, 0.05 to 0.2% one or more of imidazole bactericides and benzimidazole bactericides, 0.02 to 0.15% of a polyoxyethylene ether or a quaternary ammonium salt emulsifier, and the balance water. The citrus antistaling agent containing polyhexamethylene guanidine can obviously inhibit decomposition of citrus fruits such as sugar orange fruits and the like in storage, and especially, can inhibit sour rot. If sugar orange fruits treated by the citrus antistaling agent containing polyhexamethylene guanidine is stored at a normal temperature of 15 to 25 DEG C for 40 days, a sour rot incidence of the sugar orange fruits is below 15.4%, wherein a sour rot incidence of a control group is 76%. Therefore, the citrus antistaling agent containing polyhexamethylene guanidine obviously reduces a sour rot incidence of Citrus reticulate Blanco, and greatly improves citrus economic values.
Owner:SOUTH CHINA BOTANICAL GARDEN CHINESE ACADEMY OF SCI

Low-corrosivity peracetic acid disinfectant containing wetting agent and preparation method of low-corrosivity peracetic acid disinfectant

The invention discloses a wetting agent-containing low-corrosivity peracetic acid disinfectant and a preparation method thereof, and the peracetic acid disinfectant comprises the following components in percentage by mass: 15%-20% of hydrogen peroxide, 30%-40% of glacial acetic acid, 0.2%-2% of isomeric C10 alcohol polyoxyethylene polyoxypropylene ether, 0.5%-4% of an auxiliary agent, 0.2%-2% of persulfate, 1%-3% of a stabilizer and the balance of water. The auxiliary agent is selected from dodecyl guanidine hydrochloride or / and hexadecyl trimethyl ammonium chloride. The peracetic acid disinfectant provided by the invention has the advantages of rapid disinfection and sterilization and good effect, especially has the advantages of low corrosion to equipment, no residue, no toxicity, safety and reliability, and the peracetic acid disinfectant is simple in preparation process, convenient to operate and easy for industrial production.
Owner:广东环凯生物技术有限公司

Preparation method of rectangular separation net for deep and far sea culture

The invention provides a preparation method of a rectangular separation net for deep and far sea culture, which comprises the following steps: preparing a blended antifouling composite material, preparing a light blue monofilament bundle, preparing a rectangular separation net, and mixing polypropylene granules, a polyhexamethylene guanidine hydrochloride grafted modified polypropylene antifouling material, nano copper powder, pyrithione copper powder, tetra [beta-(3, 3, 4-trimethyl-1, 3, 4-trimethyl-1, 3, 4-trimethyl-1, 3, 4-trimethyl-1, 3, 4-trimethyl-1, 3, 4-trimethyl-1, 3, 4-trimethyl-1, 3, 4- 2, 5-di-tert-butyl-4-hydroxyphenyl) propionic acid] pentaerythritol ester, tri (1, 2, 2, 6, 6-pentamethylpiperidinyl) phosphite, phthalocyanine blue pigment, titanium dioxide and turpentine are mixed and uniformly stirred, extrusion granulation is performed 2-3 times through a double-screw extruder to obtain a blended antifouling composite material, light blue monofilament tows are obtained after wire drawing and rolling, and the light blue monofilament tows are used as raw materials. And obtaining the rectangular separation net for deep and far sea culture by using a special rectangular separation net preparation method.
Owner:EAST CHINA SEA FISHERIES RES INST CHINESE ACAD OF FISHERY SCI

Bone protein extraction without demineralization

Embodiments of the invention relate generally to protein extraction and, more generally, to bone protein extraction methods that do not require demineralization. In one embodiment, the invention provides a method comprising: mixing a bone sample and a quantity of an extraction buffer comprising: ammonium phosphate dibasic; or ammonium phosphate dibasic and ammonium bicarbonate; or ammonium phosphate dibasic, ammonium bicarbonate, and guanidine HCl; or sodium phosphate dibasic and sodium bicarbonate; or sodium phosphate dibasic, sodium bicarbonate, and guanidine HCl; or potassium phosphate dibasic and potassium bicarbonate; or potassium phosphate dibasic, potassium bicarbonate, and guanidine HCl; and incubating the bone sample / extraction buffer mixture.
Owner:RENESSELAER POLYTECHNIC INST

Method for producing adipic acid, hexamethylenediamine hydrochloride and polyhexamethylene (di)guanidine chloride from nylon-66 through depolymerization

The invention discloses a method for producing adipic acid, hexamethylenediamine hydrochloride and polyhexamethylene (di)guanidine chloride from waste nylon-66 serving as a raw amerial through depolymerization, which is characterized by comprising the following steps of: depolymerizing the waste nylon-66 by using hydrochloric acid to obtain refined adipic acid and hexamethylenediamine hydrochloride; polymerizing the hexamethylenediamine hydrochloride and dicyandiamide (in a molar ratio of 1:1) at the temperature of between 170 and 190DEG C for 1 to 3 hours to obtain a white or pale yellow solid polyhexamethylene diguanidine chloride; and adding dicyandiamide and ammonium chloride powder in a molar ratio of 1:2 into a reactor, performing reaction at high temperature for 1 to 3 hours, slowly adding hexamethylenediamine hydrochloride powder, continuously reacting for 3 to 7 hours to obtain a white or pale yellow solid polyhexamethylene guanidine chloride. The method improves production efficiency, reduces production cost, and solves the problems of difficult separation of the product hexamethylenediamine due to depolymerization, low yield and poor benefit; and the technological process is environment-friendly, simple and convenient, and is suitable for industrial production.
Owner:NINGBO UNIV

A kind of preparation method of polyguanidine adipate hydrochloride

The invention relates to a preparation method of polyguanidine adipate hydrochloride. Mix adipic acid and guanidine hydrochloride evenly, heat and melt, heating temperature is 120-160°C; add catalyst; add molecular weight regulator; the whole reaction process is subjected to water separation step, after the reaction is completed, immediately add to absolute ethanol and cool to room temperature , recrystallized, and filtered to obtain polyadipate-based guanidine hydrochloride. The polyguanidine adipate hydrochloride of the present invention improves the structure of the polyguanidine disinfectant, and introduces an electron-withdrawing group acyl group to make the guanidine group more positively charged, so its bactericidal ability is stronger.
Owner:JILIN YUNFEI PHARMA CO LTD
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