49 results about "Poly(methacrylic acid)" patented technology

The invention is directed to transfection reagents for the delivery of nucleic acids into neural cells, compositions including the reagents, methods of preparation of such reagents, methods of transfecting cells with such reagents, and uses thereof. In preferred embodiments the reagents comprise horseradish peroxidase and/or a polycarboxylic acid such as poly(acrylic acid) or poly(methacrylic acid).

The present invention relates to a liquid mixture comprising a first polymer, which is a poly(acid), a second polymer, which is a poly(ether), and at least one salt, wherein the molecular weight of the poly(acid) is in the range of 1000-100,000 Da. The second polymer is selected to be capable of forming immiscible aqueous phases in the presence of the poly(acid) and salt. The poly(acid) may be selected from the group consisting of poly(acrylic acid) and poly(methacrylic acid), and the second synthetic polymer may comprise ethylene oxide. The invention may be used for separation of biomolecules, cells or particles.

A seed or seedling is coated with underivatized guar, cationic hydroxypropyl guar, polyacrylamide, poly(methacrylic acid), poly(acrylic acid), polyacrylate, polyethylene glycol), polyethyleneoxide, poly(vinyl alcohol), polyglycerol, polytetrahydrofuran, polyamide, hydroxypropyl guar, carboxymethyl guar, carboxymethylhydroxypropyl guar, underivatized starch, cationic starch, corn starch, wheat starch, rice starch, potato starch, tapioca, waxy maize, sorghum, waxy sorghum, sago, dextrin, chitin, chitosan, xanthan gum, carageenan gum, gum karaya, gum arabic, pectin, cellulose, hydroxycellulose, hydroxyalkyl cellulose, hydroxyethyl cellulose, carboxymethylhydroxyethyl cellulose, or hydroxypropyl cellulose, the coated seed or seedling having a shelf-life at room temperature in ambient conditions in an unsealed container to at least two months.

The present invention provides a porous hollow silica micro- or nanoparticle with a polymer grafted thereon, wherein the polymer is selected from poly(methacrylic acid) and copolymers thereof. The polymer may be covalently linked to the silica particle via a bridging group. Provided is also a method of covalently coupling a poly(methacrylic acid) to a silica surface of a hollow silica particle. The method comprises contacting a silica surface of a hollow silica particle that carries amino functional or halogen functional groups with a poly(methacrylic acid) or a copolymer or a respective monomer thereof. The method further comprises allowing the carboxyl group of the monomer or the poly(methacrylic acid) and an amino functional group or a halogen functional group on the silica surface to undergo a coupling reaction, thereby covalently coupling the polymer to the silica surface.

A seed or seedling is coated with a cross-linked biopolymer and, optionally, a second binder selected from underivatized guar, cationic hydroxypropyl guar, polyacrylamide, poly(methacrylic acid), poly(acrylic acid), polyacrylate, poly(ethylene glycol), polyethyleneoxide, polyamide, hydroxypropyl guar, carboxymethyl guar, carboxymethylhydroxypropyl guar, underivatized starch, cationic starch, corn starch, wheat starch, rice starch, potato starch, tapioca, waxy maize, sorghum, waxy sarghum, sago, dextrin, chitin, chitosan, xanthan gum, carageenan gum, gum karaya, gum arabic, pectin, cellulose, hydroxycellulose, hydroxyalkyl cellulose, hydroxyethyl cellulose, carboxymethylhydroxyethyl cellulose, or hydroxypropyl cellulose. The seed coating composition is characterized by a dust value, as measured using a Heubach dustmeter device, which is lower by at least 30% as compared to an analogous composition that does not contain the crosslinked biopolymer.

The invention provides a method for preparing narrow-dispersion high-magnetic chitosan sub-micron particles. The method comprises the following steps: synthesizing sub-micron spherical Fe3O4 colloidal nanocrystal clusters (MCNCs) with carboxylic groups on the surfaces according to a solvothermal method; dispersing the MCNCs in aqueous solution including chitosan and acrylic acid/methacrylic acid; adding initiator, so as to coat chitosan-polyacrylic acid/polymethacrylic acid compound shells on the surfaces of the MCNCs through radical polymerization reaction; adding cross linking agent, so that cross linking reaction is carried out between the MCNCs and part of amino groups in chitosan molecular chains; and finally, washing out polyacrylic acid or polymethacrylic acid with alkali aqueous solution. The method has the advantages that the quantity of organic solvent used during the preparation process is low, so that organic material residue is low; the sizes of magnetic polymer particles depend on those of the pre-prepared MCNCs, so that the regulation and the control are easy, and the particle size distribution is narrow; the magnetic content of the magnetic polymer particles is uniform and high; superparamagnetism is realized; and the method is particularly suitable for being applied to separation, analysis, enzyme immobilization, catalysis and the like.

The invention discloses a catalyst for selectively oxidizing methacrylaldehyde to prepare methacrylic acid and preparation and application methods thereof. The catalyst for selectively oxidizing the methacrylaldehyde to prepare the methacrylic acid is composed of PaMobVcXxYyZz1HhOg1-Zz2Og2, wherein X is a combination of at least two from sodium, potassium, rubidium and cesium, Y is a mixture of one or at least two from calcium, magnesium, chromium, manganese, iron, cobalt, copper, nickel, zinc, aluminum, silicon, germanium, antimony, bismuth, lanthanum or cerium, and Z comprises titanium and/or zirconium. Compared with traditional phosphovanadomolybdate catalysts. The catalyst for selectively oxidizing the methacrylaldehyde to prepare the methacrylic acid can be higher in activity when applied to selectively oxidizing the methacrylaldehyde to prepare the methacrylic acid, and during the catalytic process, when the methacrylaldehyde converting rate is 90%, and the selectivity to the methacrylic acid can reach up to 93%, so that the catalyst for selectively oxidizing the methacrylaldehyde to prepare the methacrylic acid can meet the demands of practical industrial production.

A composite material includes at least one layer of fibrous material; and at least one biodegradable polymer layer composed of at least one biodegradable polymer, at least one biodegradable copolymer or both at least one biodegradable polymer and at least one biodegradable copolymer. The biodegradable polymer and biodegradable copolymer are each composed of a polymer block selected from the group consisting of poly(alkylene glycol), poly(alkylene oxide), poly(ethylene imine), polyalkylene, polyvinyl, polyvinylether, poly(vinylacetate), polyvinylpyrrolidine, polyester, polylactide, polyglycolide, polycaprolactone, poly(hydroxyalkanoate), poly(meth)acrylates, poly(acrylic acid) and salts thereof, polyether, polyurethane, poly(methacrylic acid) and salts thereof, polyacrylamide, polyepoxide, polyol, polysaccharide, and latex.

The invention discloses a continuous production method for isobornyl methacrylate. The method comprises the following steps: (1) putting methacrylic acid and camphene into a reaction kettle, after themethacrylic acid and the camphene are completely dissolved at room temperature, adding a polymerization inhibitor and a catalyst, performing a reaction, and performing filtration to obtain a reactionmixed liquid; (2) replenishing a polymerization inhibitor into the reaction mixed liquid, performing distillation to obtain unreacted methacrylic acid and camphene under negative pressure of 0.01-0.05 MPa, and collecting a fraction at the temperature of 113-120 DEG C and pressure of 0.6 kPa to obtain the isobornyl methacrylate; (3) putting the unreacted methacrylic acid and camphene into a secondary reaction kettle, performing a reaction, and performing filtration to obtain a secondary reaction mixed liquid; and (4) performing the step (2) and the step (3) on the secondary reaction mixed liquid repeatedly in sequence to realize continuous production of the isobornyl methacrylate. The method disclosed by the invention has the advantages of having a high utilization ratio of raw materials,reducing loss of the raw materials, improving a conversion rate of the raw materials, and improving product quality.

The invention provides a preparation method for an anode device of a microbial fuel cell. The preparation method comprises the following steps of dissolving methacrylic acid in dichloromethane; adding dicyclohexylcarbodiimide and alkylamine osmium bipyridine chlorate for reaction; drying an organic phase to obtain a monomer Y after washing; dissolving 2-methacryloyloxyethyl phosphorylcholine, 2-butyl methacrylate, 4-vinylbenzene boronic acid and the monomer Y in absolute ethyl alcohol; adding azodiisobutyronitrile for reaction; depositing a product in a chloroform/ethyl ether mixed solvent, dissolving the product in deionized water, and carrying out reduced pressure distillation to obtain a copolymer PMBVY; mixing the copolymer PMBVY and a culture solution loaded with Shewanella to obtain a constituent I; mixing polyvinyl alcohol and a sterile culture solution to obtain a constituent II; placing an electrode in a die; adding the constituents I and II in same volume; uniformly mixing the constituents I and II until a sol is cured; and combing the electrode, an electrode plate, a substrate and a filter net to obtain the anode device. By the method, materials are recycled, and the anode device is convenient to maintain.

The invention provides a polymer capable of responding to acid and oxidation-reduction environment, namely, a poly-methacrylic acid derivative coupled chitosan polymer. The polymer is a high-molecularsubstance, wherein the molecular weight of a hydrophobic poly-methacrylic acid derivative is 4.1 to 18.8kDa; the molecular weight of chitosan oligosaccharide is 5 to 20kDa; the deacetylation degree is 70 to 100 percent. Chitosan and the poly-methacrylic acid derivative are subjected to an amide reaction with 3,3'-dithiodipropionic acid to obtain poly-methacrylic acid derivative coupled chitosan.Nanoparticles formed by the polymer are stable in structure, and have a good passive tumor targeting effect and high in-vivo stability. The structure contains a large quantity of tertiary amine groupsand disulfide bonds capable of responding to the oxidation-reduction environment, the nanoparticles have the capability of rapidly escaping from lysosome in tumor cells and rapidly releasing medicaments in plasma, and the curative effect of an antitumor medicament in tumor treatment is enhanced.

The invention relates to a preparation method of methacrylic acid bentonite with a structure of vertically and crossly distributed lamellas. The preparation method of methacrylic acid bentonite is characterized in that alkaline calcium base soil and methacrylic acid act as raw materials, and cyclohexene acts as a dispersing agent. The preparation method comprises the following steps: putting alkaline calcium base bentonite into a three-opening flask, adding a proper amount of cyclohexene, and carrying out ultrasonic dispersion with the power of 50-900W for 1-150 minutes; then putting the three-opening flask into a water bath pot at 30-100 DEG C, and carrying out thermostatic waterbath mechanical stirring, adding a mixed solution of methacrylic acid, alcohol and residual cyclohexene dropwise, then condensing and backflowing, carrying out water diversion reaction for 0.5-12 hours, carrying out suction filtration, drying, and cooling naturally to room temperature, thereby obtaining the methacrylic acid bentonite. The organic content of methacrylic acid bentonite is as high as 30%-50%. The methacrylic acid bentonite is novel organic bentonite. Meanwhile, the preparation method enables the reaction to be more uniform and full, so that the favorable bentonite with vertically, crossly and uniformly distributed lamellas can be obtained, and moreover, the organic content is as high as 44.1%.